Reinitiation of Anticoagulation After Warfarin-Associated Intracranial Hemorrhage and Mortality Risk: The Best Practice for Reinitiating Anticoagulation Therapy After Intracranial Bleeding (BRAIN) Study

Canadian Journal of Cardiology

Volumn 28, Issue 1, 2012, Pages 33-39

  Yung, Derek ^a   Kapral, Moira K ^b,c   Asllani, Eriola ^b   Fang, Jiming ^b   Lee, Douglas S ^a,b,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

WARFARIN;

ADULT; AGED; ANTICOAGULATION; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CLINICAL PRACTICE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEART VALVE PROSTHESIS; HOSPITAL PATIENT; HUMAN; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; MORTALITY; PHASE 3 CLINICAL TRIAL; RETREATMENT; STROKE; SUBARACHNOID HEMORRHAGE; THROMBOSIS; TREATMENT OUTCOME;

AGED; ANTICOAGULANTS; CAUSE OF DEATH; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTRACRANIAL HEMORRHAGES; MALE; ONTARIO; PROGNOSIS; PROSPECTIVE STUDIES; RETREATMENT; RISK FACTORS; THROMBOSIS; WARFARIN;

EID: 84856024245     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cjca.2011.10.002     Document Type: Article

References (30)

1. Flaherty M.L., Kissela B., Woo D., et al. The increasing incidence of anticoagulant-associated intracerebral hemorrhage. Neurology 2007, 68:116-121.
2. Hart R.G., Boop B.S., Anderson D.C. Oral anticoagulants and intracranial hemorrhage. Facts and hypotheses. Stroke 1995, 26:1471-1477.
3. Rosand J., Eckman M.H., Knudsen K.A., Singer D.E., Greenberg S.M. The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage. Arch Int Med 2004, 164:880-884.
4. Gage B.F., Yan Y., Milligan P.E., et al. Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF). Am Heart J 2006, 151:713-719.
5. Radberg J.A., Olsson J.E., Radberg C.T. Prognostic parameters in spontaneous intracerebral hematomas with special reference to anticoagulant treatment. Stroke 1991, 22:571-576.
6. Sjoblom L., Hardemark H.G., Lindgren A., et al. Management and prognostic features of intracerebral hemorrhage during anticoagulant therapy: a Swedish multicenter study. Stroke 2001, 32:2567-2574.
7. Franke C.L., de J.J., van Swieten J.C., Op de Coul A.A.W., van G.J. Intracerebral hematomas during anticoagulant treatment. Stroke 1990, 21:726-730.
8. Bailey R.D., Hart R.G., Benavente O., Pearce L.A. Recurrent brain hemorrhage is more frequent than ischemic stroke after intracranial hemorrhage. Neurology 2001, 56:773-777.
9. Kapral M., Silver F., Richards J., et al. Registry of the Canadian Stroke Network: Progress Report 2001-2005 2005, Institute of Clinical Evaluative Sciences, Toronto.
10. Silver F.L., Kapral M.K., Lindsay M.P., Tu J.V., Richards J.A. International experience in stroke registries: lessons learned in establishing the Registry of the Canadian Stroke Network. Am J Prev Med 2006, 31:S235-S237.
11. Kokotailo R.A., Hill M.D. Coding of stroke and stroke risk factors using international classification of diseases, revisions 9 and 10. Stroke 2005, 36:1776-1781.
12. Arnason T., Wells P.S., van W.C., Forster A.J. Accuracy of coding for possible warfarin complications in hospital discharge abstracts. Thromb Res 2006, 118:253-262.
13. Gage B.F., Waterman A.D., Shannon W., et al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA 2001, 285:2864-2870.
14. Phan T.G., Koh M., Wijdicks E.F. Safety of discontinuation of anticoagulation in patients with intracranial hemorrhage at high thromboembolic risk. Arch Neurol 2000, 57:1710-1713.
15. Zubkov A.Y., Mandrekar J.N., Claassen D.O., et al. Predictors of outcome in warfarin-related intracerebral hemorrhage. Arch Neurol 2008, 65:1320-1325.
16. Butchart E.G., Gohlke-Barwolf C., Antunes M.J., et al. Recommendations for the management of patients after heart valve surgery. Eur Heart J 2005, 26:2463-2471.
17. Sacco R.L., Adams R., Albers G., et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Circulation 2006, 113:e409-e449.
18. Butler A.C., Tait R.C. Restarting anticoagulation in prosthetic heart valve patients after intracranial haemorrhage: a 2-year follow-up. Br J Haematol 1998, 103:1064-1066.
19. Wijdicks E.F., Schievink W.I., Brown R.D., Mullany C.J. The dilemma of discontinuation of anticoagulation therapy for patients with intracranial hemorrhage and mechanical heart valves. Neurosurgery 1998, 42:769-773.
20. Bushnell C.D., Johnston D.C., Goldstein L.B. Retrospective assessment of initial stroke severity: comparison of the NIH Stroke Scale and the Canadian Neurological Scale. Stroke 2001, 32:656-660.
21. Flibotte J.J., Hagan N., O'Donnell J., Greenberg S.M., Rosand J. Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 2004, 63:1059-1064.
22. Jauch E.C., Lindsell C.J., Adeoye O., et al. Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhage. Stroke 2006, 37:2061-2065.
23. Cucchiara B., Messe S., Sansing L., Kasner S., Lyden P. Hematoma growth in oral anticoagulant related intracerebral hemorrhage. Stroke 2008, 39:2993-2996.
24. Wagner K.R., Xi G., Hua Y., et al. Lobar intracerebral hemorrhage model in pigs: rapid edema development in perihematomal white matter. Stroke 1996, 27:490-497.
25. Xi G., Wagner K.R., Keep R.F., et al. Role of blood clot formation on early edema development after experimental intracerebral hemorrhage. Stroke 1998, 29:2580-2586.
26. Morgenstern L.B., Hemphill J.C., Anderson C., et al. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2010, 41:2108-2129.
27. Bertram M., Bonsanto M., Hacke W., Schwab S. Managing the therapeutic dilemma: patients with spontaneous intracerebral hemorrhage and urgent need for anticoagulation. J Neurol 2000, 247:209-214.
28. Hansen M.L., Sorensen R., Clausen M.T., et al. Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation. Arch Intern Med 2010, 170:1433-1441.
29. Shireman T.I., Howard P.A., Kresowik T.F., Ellerbeck E.F. Combined anticoagulant-antiplatelet use and major bleeding events in elderly atrial fibrillation patients. Stroke 2004, 35:2362-2367.
30. Connolly S.J., Ezekowitz M.D., Yusuf S., et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009, 361:1139-1151.