Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis

American Journal of Pathology

Volumn 180, Issue 2, 2012, Pages 798-810

  Mori, Shuuichi ^a   Kubo, Sachiho ^a   Akiyoshi, Takuyu ^a,b   Yamada, Shigeru ^a   Miyazaki, Tsuyoshi ^a   Hotta, Harumi ^a   Desaki, Junzo ^c   Kishi, Masahiko ^d   Konishi, Tetsuro ^e   Nishino, Yuri ^f,g,h   Miyazawa, Atsuo ^f,g,h   Maruyama, Naoki ^a   Shigemoto, Kazuhiro ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOHO UNIVERSITY   (Japan)

^e UTANO NATIONAL HOSPITAL   (Japan)

^f RIKEN SPring 8 Center   (Japan)

^g UNIVERSITY OF HYOGO   (Japan)

^h JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ANTIBODY; COLLAGEN; COLLAGEN Q; COMPLEMENT COMPONENT C5; IMMUNOGLOBULIN G1; MUSCLE SPECIFIC KINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAPHY; ENZYME ACTIVITY; FEMALE; IMMUNIZATION; MOUSE; MUSCLE WEAKNESS; MYASTHENIA GRAVIS; MYOTUBE; NEUROMUSCULAR SYNAPSE; NONHUMAN; PATHOPHYSIOLOGY; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN FUNCTION; STRAIN DIFFERENCE; SYNAPSE; WEIGHT REDUCTION;

ANIMALS; AUTOANTIBODIES; CHOLINESTERASE INHIBITORS; COMPLEMENT C5; IMMUNOGLOBULIN G; MICE; MICE, INBRED STRAINS; MUSCLE STRENGTH; MUSCLE WEAKNESS; MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL; NEUROMUSCULAR JUNCTION; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SYNAPSES; SYNAPTIC TRANSMISSION; WEIGHT LOSS;

EID: 84856022505     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.031     Document Type: Article

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