To PRESERVE and protect: Targeting the microcirculation in prevention of diabetes and its complications

Journal of Hypertension

Volumn 29, Issue 10, 2011, Pages 1859-1860

  Eringa, Etto C ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; INSULIN; VALSARTAN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DRUG DERIVATIVE; TETRAZOLE DERIVATIVE; VALINE;

ADIPOSE TISSUE; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; DIABETES MELLITUS; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; HEART; HEART MUSCLE CELL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MICROCIRCULATION; MUSCLE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NOTE; OBESITY; PRIORITY JOURNAL; TISSUE PERFUSION; VASCULAR RESISTANCE; DRUG EFFECT; FEMALE; MALE; MICROVASCULATURE; PHYSIOLOGY;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; FEMALE; HUMANS; INSULIN RESISTANCE; MALE; MICROVESSELS; TETRAZOLES; VALINE;

EID: 84856010577     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e32834b6228     Document Type: Note

References (14)

1. Levy BI, Schiffrin EL, Mourad JJ, Agostini D, Vicaut E, Safar ME, et al. Impaired tissue perfusion: a pathology common to hypertension, obesity, and diabetes mellitus. Circulation 2008;118:968-976.
2. Clerk LH, Vincent MA, Jahn LA, Liu Z, Lindner JR, Barrett EJ. Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle. Diabetes 2006;55:1436-1442. (Pubitemid 44195384)
3. Kondo I, Mizushige K, Hirao K, Nozaki S, Tsuji T, Masugata H, et al. Ultrasonographic assessment of coronary flow reserve and abdominal fat in obesity. Ultrasound Med Biol 2001;27:1199-1205. (Pubitemid 32916333)
4. Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, et al. Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metabolism 2011;13:294-307.
5. Velloso LA, Folli F, Sun XJ, White MF, Saad MJ, Kahn CR. Cross-talk between the insulin and angiotensin signaling systems. Proc Natl Acad Sci U S A 1996;93:12490-12495. (Pubitemid 26367171)
6. Cole BK, Keller SR, Wu R, Carter JD, Nadler JL, Nunemaker CS. Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice. Hypertension 2010;55:715-721.
7. Pscherer S, Heemann U, Frank H. Effect of renin-angiotensin system blockade on insulin resistance and inflammatory parameters in patients with impaired glucose tolerance. Diabetes Care 2010;33:914-919.
8. Fogari R, Preti P, Zoppi A, Mugellini A, Corradi L, Lazzari P, et al. Effect of Valsartan addition to amlodipine on insulin sensitivity in overweight-obese hypertensive patients. Intern Med 2008;47:1851-1857.
9. McMurray JJ, Holman RR, Haffner SM, Bethel MA, Holzhauer B, Hua TA, et al. Effect of Valsartan on the incidence of diabetes and cardiovascular events. N Engl J Med 2010;362:1477-1490.
10. van der Zijl NJ, Serné EH, Goossens GH, Moors C C M, IJzerman RG, Blaak EE, Diamant M. Valsartan-induced improvement in insulin sensitivity is not paralleled by changes in microvascular function in individuals with impaired glucose metabolism. J Hypertens 2011;29:1955-1962.
11. Yasue S, Masuzaki H, Okada S, Ishii T, Kozuka C, Tanaka T, et al. Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy. Am J Hypertens 2010;23:425-431.
12. Xu ZG, Lanting L, Vaziri ND, Li Z, Sepassi L, Rodriguez-Iturbe B, et al. Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade. Circulation 2005;111:1962-1969. (Pubitemid 40570216)
13. Pu Q, Brassard P, Javeshghani DM, Iglarz M, Webb RL, Amiri F, et al. Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP. J Hypertens 2008;26:322-333.
14. Savoia C, Touyz RM, Endemann DH, Pu Q, Ko EA, De CC, et al. Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients. Hypertension 2006;48:271-277. (Pubitemid 44309823)