Autophagy is involved in the early step of japanese encephalitis virus infection

Microbes and Infection

Volumn 14, Issue 2, 2012, Pages 159-168

  Li, Jin Kun ^a,b   Liang, Jian Jong ^b   Liao, Chin Len ^a   Lin, Yi Ling ^a,b,c  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

Autophagosome; Autophagy; Japanese encephalitis virus; Viral entry

Indexed keywords

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; BECLIN 1; DOUBLE STRANDED RNA; RAPAMYCIN;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; DOWN REGULATION; ENDOSOME; HUMAN; HUMAN CELL; JAPANESE ENCEPHALITIS; JAPANESE ENCEPHALITIS VIRUS; LIFE CYCLE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS PARTICLE; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; AUTOPHAGY; CELL LINE; CRICETINAE; ENCEPHALITIS VIRUS, JAPANESE; ENCEPHALITIS, JAPANESE; HUMANS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; RECOMBINANT FUSION PROTEINS; RNA, VIRAL; VIRUS REPLICATION; VIRUS UNCOATING;

FLAVIVIRUS; JAPANESE ENCEPHALITIS VIRUS;

EID: 84855997100     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2011.09.001     Document Type: Article

References (44)

1. Kroemer G., Marino G., Levine B. Autophagy and the integrated stress response. Mol. Cell 2010, 40:280-293.
2. Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
3. Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
4. Yang Z., Klionsky D.J. Eaten alive: a history of macroautophagy. Nat. Cell Biol. 2010, 12:814-822.
5. Yang Z., Klionsky D.J. Mammalian autophagy: core molecular machinery and signaling regulation. Curr. Opin. Cell Biol. 2010, 22:124-131.
6. Cuervo A.M. Autophagy: in sickness and in health. Trends Cell Biol. 2004, 14:70-77.
7. Lum J.J., DeBerardinis R.J., Thompson C.B. Autophagy in metazoans: cell survival in the land of plenty. Nat. Rev. Mol. Cell Biol. 2005, 6:439-448.
8. Sir D., Ou J.H. Autophagy in viral replication and pathogenesis. Mol. Cells 2010, 29:1-7.
9. Lin L.T., Dawson P.W., Richardson C.D. Viral interactions with macroautophagy: a double-edged sword. Virology 2010, 402:1-10.
10. Kim H.J., Lee S., Jung J.U. When autophagy meets viruses: a double-edged sword with functions in defense and offense. Semin. Immunopathol. 2010, 32:323-341.
11. Dreux M., Chisari F.V. Viruses and the autophagy machinery. Cell Cycle 2010, 9:1295-1307.
12. English L., Chemali M., Duron J., Rondeau C., Laplante A., Gingras D., Alexander D., Leib D., Norbury C., Lippe R., Desjardins M. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat. Immunol. 2009, 10:480-487.
13. King N.J., Getts D.R., Getts M.T., Rana S., Shrestha B., Kesson A.M. Immunopathology of flavivirus infections. Immunol. Cell Biol. 2007, 85:33-42.
14. Solomon T. Flavivirus encephalitis. N. Engl. J. Med. 2004, 351:370-378.
15. Lee Y.R., Lei H.Y., Liu M.T., Wang J.R., Chen S.H., Jiang-Shieh Y.F., Lin Y.S., Yeh T.M., Liu C.C., Liu H.S. Autophagic machinery activated by dengue virus enhances virus replication. Virology 2008, 374:240-248.
16. Khakpoor A., Panyasrivanit M., Wikan N., Smith D.R. A role for autophagolysosomes in dengue virus 3 production in HepG2 cells. J. Gen. Virol. 2009, 90:1093-1103.
17. Panyasrivanit M., Khakpoor A., Wikan N., Smith D.R. Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes. J. Gen. Virol. 2009, 90:448-456.
18. Panyasrivanit M., Khakpoor A., Wikan N., Smith D.R. Linking dengue virus entry and translation/replication through amphisomes. Autophagy 2009, 5:434-435.
19. Heaton N.S., Randall G. Dengue virus-induced autophagy regulates lipid metabolism. Cell Host Microbe 2010, 8:422-432.
20. Ait-Goughoulte M., Kanda T., Meyer K., Ryerse J.S., Ray R.B., Ray R. Hepatitis C virus genotype 1a growth and induction of autophagy. J. Virol. 2008, 82:2241-2249.
21. Sir D., Chen W.L., Choi J., Wakita T., Yen T.S., Ou J.H. Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response. Hepatology 2008, 48:1054-1061.
22. Dreux M., Gastaminza P., Wieland S.F., Chisari F.V. The autophagy machinery is required to initiate hepatitis C virus replication. Proc. Natl. Acad. Sci. USA 2009, 106:14046-14051.
23. Ke P.Y., Chen S.S. Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity invitro. J. Clin. Invest. 2011, 121:37-56.
24. Lin Y.L., Liao C.L., Yeh C.T., Chang C.H., Huang Y.L., Huang Y.Y., Jan J.T., Chin C., Chen L.K. A highly attenuated strain of Japanese encephalitis virus induces a protective immune response in mice. Virus Res. 1996, 44:45-56.
25. Chen L.K., Lin Y.L., Liao C.L., Lin C.G., Huang Y.L., Yeh C.T., Lai S.C., Jan J.T., Chin C. Generation and characterization of organ-tropism mutants of Japanese encephalitis virus invivo and invitro. Virology 1996, 223:79-88.
26. Liao C.L., Lin Y.L., Wang J.J., Huang Y.L., Yeh C.T., Ma S.H., Chen L.K. Effect of enforced expression of human bcl-2 on Japanese encephalitis virus-induced apoptosis in cultured cells. J. Virol. 1997, 71:5963-5971.
27. Liang J.J., Liao C.L., Liao J.T., Lee Y.L., Lin Y.L. A Japanese encephalitis virus vaccine candidate strain is attenuated by decreasing its interferon antagonistic ability. Vaccine 2009, 27:2746-2754.
28. Lin Y.L., Huang Y.L., Ma S.H., Yeh C.T., Chiou S.Y., Chen L.K., Liao C.L. Inhibition of Japanese encephalitis virus infection by nitric oxide: antiviral effect of nitric oxide on RNA virus replication. J. Virol. 1997, 71:5227-5235.
29. Wu Y.T., Tan H.L., Shui G., Bauvy C., Huang Q., Wenk M.R., Ong C.N., Codogno P., Shen H.M. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J. Biol. Chem. 2010, 285:10850-10861.
30. Welsch S., Miller S., Romero-Brey I., Merz A., Bleck C.K., Walther P., Fuller S.D., Antony C., Krijnse-Locker J., Bartenschlager R. Composition and three-dimensional architecture of the dengue virus replication and assembly sites. Cell Host Microbe 2009, 5:365-375.
31. Gordon P.B., Seglen P.O. Prelysosomal convergence of autophagic and endocytic pathways. Biochem. Biophys. Res. Commun. 1988, 151:40-47.
32. Pelkmans L., Helenius A. Insider information: what viruses tell us about endocytosis. Curr. Opin. Cell Biol. 2003, 15:414-422.
33. Mukhopadhyay S., Kuhn R.J., Rossmann M.G. A structural perspective of the flavivirus life cycle. Nat. Rev. Microbiol. 2005, 3:13-22.
34. Zhao Z., Date T., Li Y., Kato T., Miyamoto M., Yasui K., Wakita T. Characterization of the E-138 (Glu/Lys) mutation in Japanese encephalitis virus by using a stable, full-length, infectious cDNA clone. J. Gen. Virol. 2005, 86:2209-2220.
35. Chiou S.S., Chen W.J. Phenotypic changes in the Japanese encephalitis virus after one passage in Neuro-2a cells: generation of attenuated strains of the virus. Vaccine 2007, 26:15-23.
36. Yu C.Y., Hsu Y.W., Liao C.L., Lin Y.L. Flavivirus infection activates the XBP1 pathway of the unfolded protein response to cope with endoplasmic reticulum stress. J. Virol. 2006, 80:11868-11880.
37. Su H.L., Liao C.L., Lin Y.L. Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response. J. Virol. 2002, 76:4162-4171.
38. Hara T., Nakamura K., Matsui M., Yamamoto A., Nakahara Y., Suzuki-Migishima R., Yokoyama M., Mishima K., Saito I., Okano H., Mizushima N. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006, 441:885-889.
39. Komatsu M., Waguri S., Chiba T., Murata S., Iwata J., Tanida I., Ueno T., Koike M., Uchiyama Y., Kominami E., Tanaka K. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006, 441:880-884.
40. Orvedahl A., Levine B. Autophagy and viral neurovirulence. Cell. Microbiol. 2008, 10:1747-1756.
41. Liang X.H., Kleeman L.K., Jiang H.H., Gordon G., Goldman J.E., Berry G., Herman B., Levine B. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J. Virol. 1998, 72:8586-8596.
42. Orvedahl A., MacPherson S., Sumpter R., Talloczy Z., Zou Z., Levine B. Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe 2010, 7:115-127.
43. Orvedahl A., Alexander D., Talloczy Z., Sun Q., Wei Y., Zhang W., Burns D., Leib D.A., Levine B. HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe 2007, 1:23-35.
44. Leib D.A., Alexander D.E., Cox D., Yin J., Ferguson T.A. Interaction of ICP34.5 with Beclin 1 modulates herpes simplex virus type 1 pathogenesis through control of CD4+T-cell responses. J. Virol. 2009, 83:12164-12171.