Single-flap approach for surgical debridement of deep intraosseous defects: A randomized controlled trial

Journal of Periodontology

Volumn 83, Issue 1, 2012, Pages 27-35

  Trombelli, Leonardo ^a   Simonelli, Anna ^a   Schincaglia, Gian Pietro ^b   Cucchi, Alessandro ^a   Farina, Roberto ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Alveolar bone loss; Periodontitis; Reconstructive surgical procedures; Surgical flaps

Indexed keywords

ADULT; ALVEOLAR BONE LOSS; ANALYSIS OF VARIANCE; ARTICLE; CHI SQUARE DISTRIBUTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GINGIVA DISEASE; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MINIMALLY INVASIVE SURGERY; ORAL SURGERY; PERIODONTICS; PLASTIC SURGERY; PREVENTIVE DENTISTRY; RADIOGRAPHY; RANDOMIZED CONTROLLED TRIAL; SUTURING METHOD; TREATMENT OUTCOME;

ADULT; ALVEOLAR BONE LOSS; ANALYSIS OF VARIANCE; CHI-SQUARE DISTRIBUTION; DENTAL SCALING; FEMALE; GINGIVAL RECESSION; HUMANS; MALE; MIDDLE AGED; ORAL SURGICAL PROCEDURES; PERIODONTAL DEBRIDEMENT; PERIODONTAL INDEX; SURGICAL FLAPS; SURGICAL PROCEDURES, MINIMALLY INVASIVE; SUTURE TECHNIQUES; TREATMENT OUTCOME;

EID: 84855990773     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2011.110045     Document Type: Article

References (47)

1. Linghorne WJ, O'Connell DC. Studies in the regeneration and reattachment of supporting structures of the teeth; soft tissue reattachment. J Dent Res 1950;29: 419-428.
2. Hiatt WH, Stallard RE, Butler ED, Badgett B. Repair following mucoperiosteal flap surgery with full gingival retention. J Periodontol 1968;39:11-16.
3. Polson AM, Proye MP. Fibrin linkage: A precursor for new attachment. J Periodontol 1983;54:141-147. (Pubitemid 13082334)
4. WikesjöUM, Claffey N, Egelberg J. Periodontal repair in dogs. Effect of heparin treatment of the root surface. J Clin Periodontol 1991;18:60-64.
5. Takei HH. Surgical techniques for reconstructive periodontics. Dent Clin North Am 1991;35:531-539.
6. Trombelli L. Flap designs and suturing techniques to optimize reconstructive outcomes. In: Sculean A, ed. Periodontal Regenerative Therapy. Berlin, Quintessenz Verlags-GmbH; 2010:241-258.
7. Trombelli L, Farina R. Flap design for periodontal healing. In: Larjava H, ed. Oral Wound Healing: Cell Biology and Clinical Management. Ames: Blackwell-Wiley; 2011; in press.
8. Tu YK, Tugnait A, Clerehugh V. Is there a temporal trend in the reported treatment efficacy of periodontal regeneration? A meta-analysis of randomized-controlled trials. J Clin Periodontol 2008;35:139-146.
9. Needleman IG, Worthington HV, Giedrys-Leeper E, Tucker RJ. Guided tissue regeneration for periodontal infra-bony defects. Cochrane Database Syst Rev 2006; 19:CD001724.
10. Esposito M, Grusovin MG, Papanikolaou N, Coulthard P, Worthington HV. Enamel matrix derivative (Emdogain( R)) for periodontal tissue regeneration in intrabony defects. Cochrane Database Syst Rev 2009;7: CD003875.
11. Trombelli L, Farina R, Franceschetti G, Minenna L. Single flap approach in periodontal reconstructive surgery (in Italian). Dent Cadmos 2007;8:15-25.
12. Trombelli L, Farina R, Franceschetti G, Minenna L. Management of the soft tissues according to the principles of the single flap approach in the treatment of periodontal intraosseous defects (in Italian). Dental Clinics 2008;3:1-8.
13. Trombelli L, Farina R, Franceschetti G, Calura G. Single-flap approach with buccal access in periodontal reconstructive procedures. J Periodontol 2009;80: 353-360.
14. Trombelli L, Simonelli A, Pramstraller M, WikesjöUM, Farina R. Single flap approach with and without guided tissue regeneration and a hydroxyapatite biomaterial in the management of intraosseous periodontal defects. J Periodontol 2010;81:1256-1263.
15. Mörmann W, Ciancio SG. Blood supply of human gingiva following periodontal surgery. A fluorescein angiographic study. J Periodontol 1977;48:681-692. (Pubitemid 8223416)
16. Mörmann W, Meier C, Firestone A. Gingival blood circulation after experimental wounds in man. J Clin Periodontol 1979;6:417-424. (Pubitemid 10218272)
17. Nobuto T, Imai H, Suwa F, et al. Microvascular response in the periodontal ligament following mucoperiosteal flap surgery. J Periodontol 2003;74:521-528. (Pubitemid 36553390)
18. Nobuto T, Suwa F, Kono T, et al. Microvascular response in the periosteum following mucoperiosteal flap surgery in dogs: Angiogenesis and bone resorption and formation. J Periodontol 2005;76:1346-1353. (Pubitemid 41245780)
19. Retzepi M, Tonetti M, Donos N. Comparison of gingival blood flow during healing of simplified papilla preservation and modified Widman flap surgery: A clinical trial using laser Doppler flowmetry. J Clin Periodontol 2007;34:903-911.
20. Cortellini P, Tonetti MS. Improved wound stability with a modified minimally invasive surgical technique in the regenerative treatment of isolated interdental intrabony defects. J Clin Periodontol 2009;36:157-163.
21. O'Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol 1972;43:38.
22. Cortellini P, Prato GP, Tonetti MS. The simplified papilla preservation flap. A novel surgical approach for the management of soft tissues in regenerative procedures. Int J Periodontics Restorative Dent 1999; 19:589-599.
23. Cortellini P, Prato GP, Tonetti MS. The modified papilla preservation technique. A new surgical approach for interproximal regenerative procedures. J Periodontol 1995;66:261-266.
24. Cortellini P, Tonetti MS. Clinical performance of a regenerative strategy for intrabony defects: Scientific evidence and clinical experience. J Periodontol 2005; 76:341-350. (Pubitemid 40668378)
25. Windisch P, Sculean A, Klein F, et al. Comparison of clinical, radiographic, and histometric measurements following treatment with guided tissue regeneration or enamel matrix proteins in human periodontal defects. J Periodontol 2002;73:409-417. (Pubitemid 34467356)
26. Trombelli L, Heitz-Mayfield LJ, Needleman I, Moles D, Scabbia A. A systematic review of graft materials and biological agents for periodontal intraosseous defects. J Clin Periodontol 2002;29(Suppl. 3):117-135, discussion 160-162. (Pubitemid 41719447)
27. Trombelli L. Which reconstructive procedures are effective for treating the periodontal intraosseous defect? Periodontol 2000 2005;37:88-105. (Pubitemid 43034333)
28. Lang NP. Focus on intrabony defects -Conservative therapy. Periodontol 2000 2000;22:51-58.
29. Harrel SK. A minimally invasive surgical approach for periodontal regeneration: Surgical technique and observations. J Periodontol 1999;70:1547-1557.
30. Harrel SK, Wilson TG, Nunn ME. Prospective assessment of the use of enamel matrix proteins with minimally invasive surgery. J Periodontol 2005;76:380-384. (Pubitemid 40668383)
31. Cortellini P, Tonetti MS. Minimally invasive surgical technique and enamel matrix derivative in intra-bony defects. I: Clinical outcomes and morbidity. J Clin Periodontol 2007;34:1082-1088.
32. Cortellini P, Pini Prato G, Tonetti MS. Periodontal regeneration of human intrabony defects with titanium reinforced membranes. A controlled clinical trial. J Periodontol 1995;66:797-803.
33. Cortellini P, Pini Prato G, Tonetti MS. Periodontal regeneration of human intrabony defects with bioresorbable membranes. A controlled clinical trial. J Periodontol 1996;67:217-223. (Pubitemid 126613560)
34. Trombelli L, Kim CK, Zimmerman GJ, WikesjöUM. Retrospective analysis of factors related to clinical outcome of guided tissue regeneration procedures in intrabony defects. J Clin Periodontol 1997;24:366-371. (Pubitemid 127731536)
35. Paolantonio M, D'Archivio D, Di Placido G, et al. Expanded polytetrafluoroethylene and dental rubber dam barrier membranes in the treatment of periodontal intrabony defects. A comparative clinical trial. J Clin Periodontol 1998;25:920-928. (Pubitemid 128706542)
36. Zucchelli G, Sforza NM, Clauser C, Cesari C, De Sanctis M. Topical and systemic antimicrobial therapy in guided tissue regeneration. J Periodontol 1999;70: 239-247. (Pubitemid 29180791)
37. Silvestri M, Ricci G, Rasperini G, Sartori S, Cattaneo V. Comparison of treatments of infrabony defects with enamel matrix derivative, guided tissue regeneration with a nonresorbable membrane and Widman modified flap. A pilot study. J Clin Periodontol 2000;27: 603-610.
38. Zucchelli G, Bernardi F, Montebugnoli L, De SM. Enamel matrix proteins and guided tissue regeneration with titanium-reinforced expanded polytetrafluoroethylene membranes in the treatment of infrabony defects: A comparative controlled clinical trial. J Periodontol 2002;73:3-12. (Pubitemid 34213452)
39. Trombelli L, Bottega S, Zucchelli G. Supracrestal soft tissue preservation with enamel matrix proteins in treatment of deep intrabony defects. J Clin Periodontol 2002;29:433-439. (Pubitemid 41697830)
40. Francetti L, Del Fabbro M, Basso M, Testori T, Weinstein R. Enamel matrix proteins in the treatment of intra-bony defects. A prospective 24-month clinical trial. J Clin Periodontol 2004;31:52-59. (Pubitemid 38623831)
41. Zanetta-Barbosa D, Klinge B, Svensson H. Laser Doppler flowmetry of blood perfusion in mucoperiosteal flaps covering membranes in bone augmentation and implant procedures. A pilot study in dogs. Clin Oral Implants Res 1993;4:35-38.
42. Vergara JA, Quiñones CR, Nasjleti CE, Caffesse RG. Vascular response to guided tissue regeneration procedures using nonresorbable and bioabsorbable membranes in dogs. J Periodontol 1997;68:217-224. (Pubitemid 127517392)
43. Sculean A, Kiss A, Miliauskaite A, Schwarz F, Arweiler NB, Hannig M. Ten-year results following treatment of intra-bony defects with an enamel matrix proteins and guided tissue regeneration. J Clin Periodontol 2008; 35:817-824.
44. Holm-Pedersen P, Löe H. Wound healing in the gingival of young and old individuals. Scand J Dent Res 1971; 79:40-53.
45. Garrett S. Periodontal regeneration around natural teeth. Ann Periodontol 1996;1:621-666.
46. Cortellini P, Labriola A, Tonetti MS. Regenerative periodontal therapy in intrabony defects: State of the art. Minerva Stomatol 2007;56:519-539.
47. Tal H. The prevalence and distribution of intrabony defects in dry mandibles. J Periodontol 1984;55:149-154.