Development of a new screening method for the detection of antibiotic residues in muscle tissues using liquid chromatography and high resolution mass spectrometry with a LC-LTQ-Orbitrap instrument

Food Additives and Contaminants - Part A

Volumn 28, Issue 10, 2011, Pages 1340-1351

  Hurtaud Pessel, D ^a   Jagadeshwar Reddy, T ^a   Verdon, E ^a  

^a FRENCH AGENCY FOR FOOD   (France)

Author keywords

animal products, meat; LC MS; veterinary drug residues, antibiotics

Indexed keywords

AMIDES; ANIMALS; CHROMATOGRAPHIC ANALYSIS; DATA HANDLING; DIAGNOSIS; HISTOLOGY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; MUSCLE; SULFUR COMPOUNDS; TISSUE ENGINEERING; VETERINARY MEDICINE;

ANIMAL PRODUCTS , MEATS; ANTIBIOTIC RESIDUES; AUTOMATED DATA PROCESSING; EXTRACTION PROTOCOLS; HIGH RESOLUTION MASS SPECTROMETRY; LC/MS; LIQUID CHROMATOGRAPHY-HIGH RESOLUTION MASS SPECTROMETRIES; VETERINARY DRUG RESIDUES , ANTIBIOTICS;

ANTIBIOTICS;

AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; APRAMYCIN; CEFAPIRIN; CEFAZOLIN; CEFQUINOME; CEFTIOFUR; CIPROFLOXACIN; CLOXACILLIN; DIFLOXACIN; FLUMEQUINE; KANAMYCIN; LINCOMYCIN; NALIDIXIC ACID; NORFLOXACIN; OXACILLIN; PAROMOMYCIN; PENICILLIN G; SPECTINOMYCIN; SPIRAMYCIN; STREPTOMYCIN; SULFADIAZINE; SULFADOXINE; SULFATHIAZOLE; TETRACYCLINE; TILMICOSIN; TULATHROMYCIN; TYLOSIN; UNINDEXED DRUG;

ANIMAL TISSUE; ARTICLE; COMPUTER PROGRAM; DATA PROCESSING; DRUG ISOLATION; DRUG SCREENING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MASS SPECTROMETRY; MUSCLE TISSUE; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT;

ANIMALIA;

EID: 84855973161     PISSN: 19440049     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/19440049.2011.605772     Document Type: Article

References (24)

1. Bohm, DA, Stachel, CS and Gowik, P. 2009. Multi-method for the determination of antibiotics of different substance groups in milk and validation in accordance with Commission Decision 2002/657/EC. J Chromatogr A, 1216(46): 8217-8223.
2. Commission Decision. 2002/657/EC of 12 August 2002. Off J Eur Commun. L221:8-36
3. Commission Regulation No. 37/2010 (EU) of 22 December 2009. Off J Eur Commun. L15:1-72
4. Dervilly-Pinel, G, Weigel, S, Lommen, A, Chereau, S, Rambaud, L and Essers, M. Antignac J-P, Nielen MWF, Le Bizec B. 2011. Assessment of two complementary liquid chromatography coupled to high resolution mass spectrometry metabolomics strategies for the screening of anabolic steroid treatment in calves. Anal Chim Acta. 700(1-2): 144-154
5. European Union. 2010. Community Reference Laboratories. Guidelines for the validation of screening methods for residues of veterinary medicines. Available from: http://ec.europa.eu/food/food/chemicalsafety/residues/lab_analysis_en.htm
6. Gaudin, V, Hedou, C, Rault, A and Verdon, E. 2010. Validation of a five plate test, the STAR protocol, for the screening of antibiotic residues in muscle from different animal species according to European Decision 2002/657/EC. Food Addit Contam A, 27(7): 935-952.
7. Gaugain-Juhel, M, Delépine, B, Gautier, S, Fourmond, MP, Gaudin, V, Hurtaud-Pessel, D, Verdon, E and Sanders, P. 2009. Validation of a liquid chromatography-tandem mass spectrometry screening method to monitor 58 antibiotics in milk: a qualitative approach. Food Addit Contam A, 26(11): 1459-1471.
8. Gerssen, A, Mulder, P and De Boer, J. 2011. Screening of lipophilic marine toxins in shellfish and algae: development of a library using liquid chromatography coupled to orbitrap mass spectrometry. Anal Chim Acta, 685: 176-185.
9. Granelli, K and Branzell, C. 2007. Rapid multi-residue screening of antibiotics in muscle and kidney by liquid chromatography-electrospray ionization-tandem mass spectrometry. Anal Chim Acta, 586: 289-295.
10. Hogenboom, AC, van Leerdam, JA and de Voogt, P. 2009. Accurate mass screening and identification of emerging contaminants in environmental samples by liquid chromatography-hybrid linear ion trap Orbitrap mass spectrometry. J Chromatogr A, 1216(3): 510-519.
11. Hurtaud-Pessel, D, Gautier, S, Gaugain-Juhel, M and Verdon, E. 2008. Screening of veterinary antibacterial residues in muscle using liquid chromatography-tandem mass spectrometry: method validation. Proceedings of the EuroResidue VI Conference on residues of veterinary drugs in food. 2008. vol. 3, p. 1317-1322
12. Inchauspe, G, Delrieu, P, Dupin, P, Laurent, M and Samain, D. 1987. Mechanism of selectivity in ion-pair high performance liquid chromatography of aminoglycoside antibiotics using perfluorinated pairing ions. J Chromatogr, 404: 53-66.
13. Kaufmann, A, Butcher, P, Maden, K and Widmer, M. 2007. Ultra-performance liquid chromatography coupled to time of flight mass spectrometry (UPLC-TOF): a novel tool for multiresidue screening of veterinary drugs in urine. Anal Chim Acta, 586(1-2): 13-21.
14. Kaufmann, A, Butcher, P, Maden, K and Widmer, M. 2008. Quantitative multiresidue method for about 100 veterinary drugs in different meat matrices by sub 2-μm particulate high-performance liquid chromatography coupled to time of flight mass spectrometry. J Chromatogr A, 1194(1): 66-79.
15. Kilinc, B, Meyer, C and Hilge, V. 2007. Evaluation of the EEC four-plate test and Premi test for screening antibiotic residues in trout (Salmo trutta). Int J Food Sci Technol, 42: 625-628.
16. Moulard, Y, Bailly-Chouriberry, L, Boyer, S, Garcia, P, Popot, M-A and Bonnaire, Y. 2011. Use of benchtop exactive high resolution and high mass accuracy orbitrap mass spectrometer for screening in horse doping control. Anal Chim Acta, 700(1-2): 126-136.
17. Ortelli, D, Cognard, E, Jan, P and Edder, P. 2009. Comprehensive fast multiresidue screening of 150 veterinary drugs in milk by ultra-performance liquid chromatography coupled to time of flight mass spectrometry. J Chromatogr B, 877(23): 2363-2374.
18. Peters, RJB, Bolck, YJC, Rutgers, P, Stolker, AAM and Nielen, MWF. 2009. Multi-residue screening of veterinary drugs in egg, fish and meat using high-resolution liquid chromatography accurate mass time-of-flight mass spectrometry. J Chromatogr A, 1216(46): 8206-8216.
19. Petrovic, M, Gros, M and Barcelo, D. 2006. Multi-residue analysis of pharmaceuticals in wastewater by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. J Chromatogr A, 1124(1-2): 68-81.
20. Pikkemaat, MG. 2009. Microbial screening methods for detection of antibiotic residues in slaughter animals. Anal Bioanal Chem, 395: 893-905.
21. Pikkemaat, MG, Rapallini, ML, Oostra-van Dijk, S and Elferink, JWA. 2009. Comparison of three microbial screening methods for antibiotics using routine monitoring samples. Anal Chim Acta, 637: 298-304.
22. Skrabakova, Z, O'Halloran, J, Van Pelt, F and James, K. 2010. Food contaminant analysis at ultra-high mass resolution: application of hybrid linear ion trap-orbitrap mass spectrometry for the determination of the polyether toxins, azaspiracids, in shellfish. Rapid Commun Mass Spectrom, 24: 2966-2974.
23. Stolker, AAM, Rutgers, P, Oosterink, E, Lasaroms, JJP, Peters, RJB, Van Rhijn, JA and Nielen, MWF. 2008. Comprehensive screening and quantification of veterinary drugs in milk using UPLC-ToF-MS. Anal Bioanal Chem, 391(6): 2309-2322.
24. Yamada, R, Kozono, M, Ohmori, T, Morimatsu, F and Kitayama, M. 2006. Simultaneous determination of residual veterinary drugs in bovine, porcine, and chicken muscle using liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Biosci Biotechnol Biochem, 70(1): 54-65.