Guide to virtual screening: Application to the akt phosphatase PHLPP

Methods in Molecular Biology

Volumn 819, Issue , 2012, Pages 561-573

  Sinko, William ^a   Sierecki, Emma ^a   De Oliveira, César A F ^a   McCammon, J Andrew ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Akt phosphatase; Computer aided drug design; Docking; Drug discovery; PHLPP; Virtual screening

Indexed keywords

ENZYME INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE B;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER INTERFACE; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; HUMAN; METABOLISM; METHODOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY;

DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; PHOSPHOPROTEIN PHOSPHATASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-AKT; STRUCTURAL HOMOLOGY, PROTEIN; USER-COMPUTER INTERFACE;

EID: 84855962146     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-465-0_33     Document Type: Article

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