A founder BRCA2 mutation in non-Afrikaner breast cancer patients of the Western Cape of South Africa

Clinical Genetics

Volumn 81, Issue 2, 2012, Pages 179-184

  van der Merwe, N C ^a,b   Hamel, N ^c,d   Schneider, S R ^b   Apffelstaedt, J P ^e   Wijnen, J T ^f   Foulkes, W D ^c,d,g  

^a UNIVERSITY OF THE FREE STATE   (South Africa)

^b NATIONAL HEALTH LABORATORY SERVICE   (South Africa)

^c RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^d MCGILL UNIVERSITY   (Canada)

^e STELLENBOSCH UNIVERSITY   (South Africa)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^g MCGILL UNIVERSITY   (Canada)

Author keywords

Gene flow; Haplotype; Hereditary cancer; Human genetics; Southern hemisphere

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER SCREENING; EXON; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENETIC SCREENING; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN TRUNCATION TEST; SOUTH AFRICA;

ADULT; AGED; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; EXONS; FEMALE; FOUNDER EFFECT; HAPLOTYPES; HUMANS; MIDDLE AGED; MUTATION; NEOPLASM STAGING; PREVALENCE; SOUTH AFRICA;

EID: 84855957413     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2010.01617.x     Document Type: Article

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