A sensitive liquid chromatographic method for the analysis of clarithromycin with pre-column derivatization: Application to a bioequivalence study

Iranian Journal of Basic Medical Sciences

Volumn 12, Issue 1, 2009, Pages 25-32

  Farshchi, Amir ^a,b   Ghiasi, Golbarg ^a,b   Bahrami, Gholamreza ^a,c  

^a KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Bioequivalence; Clarithromycin; High performance liquid chromatography; Macrolide antibiotics

Indexed keywords

AMANTADINE; CLARITHROMYCIN; PLACEBO;

ADULT; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD ANALYSIS; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STABILITY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MALE; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; NORMAL HUMAN; PH; PHARMACOKINETIC PARAMETERS; PRECOLUMN DERIVATIZATION; PRODUCT RECOVERY; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION PROCESS;

EID: 84855956237     PISSN: 20083866     EISSN: 20083874     Source Type: Journal    
DOI: 10.22038/IJBMS.2009.5131     Document Type: Article

References (15)

1. Chambers HF. Chloramphenicol, Tetracyclines, Macrolides, Clindamycin, and Streptogramins. In: Katzung BG. editor. Basic and clinical pharmacology. New York, NY: McGraw-Hill; 2004.p.760.
2. Chu SY, Sennello LT, Sonders RC. Simultaneous determination of clarithromycin and 14(R)-hydroxyclarithromycin in plasma and urine using high-performance liquid chromatography with electrochemical detection. J Chromatogr 1991; 57:199.
3. Hedenmo M, Eriksson BM. Liquid chromatographic determination of the macrolide antibiotics roxithromycin and clarithromycin in plasma by automated solid-phase extraction and electrochemical detection. J Chromatogr A 1995; 692:161.
4. Taninaka PC, Ohtani H, Hanada E, Kotaki H, Sato H, Iga T. Determination of erythromycin, clarithromycin, roxithromycin, and azithromycin in plasma by high-performance liquid chromatography with amperometric detection. J Chromatogr B 2000; 738:405.
5. Niopas I, Daftsios AC. Determination of clarithromycin in human plasma by HPLC with electrochemical detection: validation and application in pharmacokinetic study. Biomed Chromatogr 2001; 15:507.
6. Choi SJ, Kim SB, Lee H-Y, Na DH, Soon YS, Lee SS, et al. Column-switching high-performance liquid chromatographic determination of clarithromycin in human plasma with electrochemical detection. Talanta 2001; 54:377.
7. Pappa-Louisi A, Papageorgiou A, Zitrou A, Sotiropoulos S, Georgarakis E, Zougrou F. Study on the electrochemical detection of the macrolide antibiotics clarithromycin and roxithromycin in reversed-phase highperformance liquid chromatography. J Chromatogr B 2001; 755: 57.
8. Kees F, Spangler S, Wellnhofer M. Determination of macrolides in biological matrices by high-performance liquid chromatography with electrochemical detection J Chromatogr A 1998;812:287.
9. Wibawa JID, Shaw PN, Barrett DA. Quantification of clarithromycin, its 14-hydroxy and decladinose metabolites in rat plasma, gastric juice and gastric tissue using high-performance liquid chromatography with electrochemical detection. J Chromatogr B 2003; 783:359.
10. Van Rooyen GF, Smit MJ, De Jager AD, Hundt HKL, Swart KJ, Hundt AF. Sensitive liquid chromatography-tandem mass spectrometry method for the determination of clarithromycin in human plasma. J Chromatogr B 2002; 768:223.
11. Amini H, Ahmadiani A. Sensitive determination of clarithromycin in human plasma by high-performance liquid chromatography with spectrophotometric detection. J Chromatogr B 2005; 817:193.
12. Torano JS, Guchelaar HJ. Quantitative determination of the macrolide antibiotics erythromycin, roxithromycin, azithromycin and clarithromycin in human serum by high-performance liquid chromatography using pre-column derivatization with 9-fluorenylmethyloxycarbonyl chloride and fluorescence detection. J Chromatogr B 1998; 720: 89.
13. Bahrami Gh, Mirzaeei Sh, Kiani A. High performance liquid chromatographic determination of azithromycin in serum using fluorescence detection and its application in human pharmacokinetic studies. J Chromatogr B 2005; 820:277.
14. Bahrami Gh, Mohammadi B. A new on-line, in-tube pre-column derivatization technique for high performance liquid chromatographic determination of azithromycin in human serum. J Chromatogr B 2006; 830:355.
15. Hori T, Hashimoto H, Konishi M. Determination of erythromycin A in rat plasma and urine by highperformance liquid chromatography with chemiluminescence detection using Tris (2,2-bipyridine) ruthenium (II). Biomed Chromatogr 2006; 20:17.