Modelling of mouse experimental colitis by global property screens: A holistic approach to assess drug effects in inflammatory bowel disease

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Gottfries, Johan ^a   Melgar, Silvia ^b   Michaëlsson, Erik ^c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; AZ 15188; AZ 37328; AZ 63233; DEXTRAN SULFATE; LIVER X RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; UNCLASSIFIED DRUG; AUTACOID; BIOLOGICAL MARKER; CYTOKINE; HAPTOGLOBIN; LIVER X RECEPTOR; ORPHAN NUCLEAR RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLITIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DRUG EFFICACY; FEMALE; GLOBAL PROPERTY SCREENING; MOUSE; NONHUMAN; PREDICTION; PRINCIPAL COMPONENT ANALYSIS; TREATMENT RESPONSE; ANIMAL; BAGG ALBINO MOUSE; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; COLON; DRUG EFFECT; DRUG POTENTIATION; ENTERITIS; HUMAN; METABOLISM; PATHOLOGY; PHILOSOPHY;

ANIMALIA; MUS;

ANIMALS; BIOLOGICAL MARKERS; COLITIS; COLON; CYTOKINES; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; FEMALE; HAPTOGLOBINS; HOLISTIC HEALTH; HUMANS; INFLAMMATION MEDIATORS; INFLAMMATORY BOWEL DISEASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; PPAR ALPHA; PPAR GAMMA; PRINCIPAL COMPONENT ANALYSIS;

EID: 84855955921     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030005     Document Type: Article

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