Dedifferentiated leiomyosarcoma: Clinicopathological analysis of 18 cases

Histopathology

Volumn 59, Issue 6, 2011, Pages 1135-1143

  Chen, Eleanor ^a   O'Connell, Fionnuala ^b   Fletcher, Christopher D M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b University College Cork and INFANT Centre   (Ireland)

Author keywords

Dedifferentiation; Leiomyosarcoma; Sarcoma; Soft tissue

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER GRADING; CANCER MORTALITY; CANCER RECURRENCE; CANCER SIZE; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL STRUCTURE; CLINICAL ARTICLE; DEDIFFERENTIATED LEIOMYOSARCOMA; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; LEIOMYOSARCOMA; LIMB; MALE; METASTASIS; PRIORITY JOURNAL; PROSTATE; RETROPERITONEUM; TRUNK; UTERUS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELL DIFFERENTIATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LEIOMYOSARCOMA; MALE; MIDDLE AGED; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84855955187     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2011.04070.x     Document Type: Article

References (34)

1. Bertoni F, Bacchini P, Staals EL et al. Dedifferentiated parosteal osteosarcoma: the experience of the Rizzoli Institute. Cancer 2005; 103; 2373-2382.
2. McCormick D, Mentzel T, Beham A, Fletcher CD. Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. Am. J. Surg. Pathol. 1993; 18; 1213-1223.
3. Brooks JJ. The significance of double phenotypic patterns and markers in human sarcomas. A new model of mesenchymal differentiation. Am. J. Pathol. 1986; 125; 113-123.
4. Dahlin DC, Beabout JW. Dedifferentiation of low-grade chondrosarcomas. Cancer 1971; 28; 461-466.
5. Dervan PA, O'Loughlin J, Hurson BJ. Dedifferentiated chondrosarcoma with muscle and cytokeratin differentiation in the anaplastic component. Histopathology 1988; 12; 517-526.
6. Evans HL. Liposarcoma. A study of 55 cases with a reassessment of its classification. Am. J. Surg. Pathol. 1979; 3; 507-523.
7. Henricks WH, Chu YC, Goldblum JR et al. Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation. Am. J. Surg. Pathol. 1997; 21; 271-281.
8. Meis JM, Raymond AK, Evans HL et al. 'Dedifferentiated' chordoma. A clinicopathologic and immunohistochemical study of three cases. Am. J. Surg. Pathol. 1987; 11; 516-525.
9. Mosquera JM, Fletcher CD. Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component-is this dedifferentiated SFT? Am. J. Surg. Pathol. 2009; 33; 1314-1321.
10. Reith JD, Bauer TW, Fischler DF et al. Dedifferentiated chondrosarcoma with rhabdomyosarcomatous differentiation. Am. J. Surg. Pathol. 1996; 20; 293-298.
11. Shuhaibar H, Friedman L. Dedifferentiated parosteal osteosarcoma with high-grade osteoclast-rich osteogenic sarcoma at presentation. Skelet. Radiol. 1998; 27; 574-577.
12. Takeuchi K, Morii T, Yabe H et al. Dedifferentiated parosteal osteosarcoma with well-differentiated metastases. Skelet. Radiol. 2006; 35; 778-782.
13. Di Palma S, Corletto V, Lavarino C et al. Unilateral aneuploid dedifferentiated acinic cell carcinoma associated with bilateral-low grade diploid acinic cell carcinoma of the parotid gland. Virchows Arch. 1999; 434; 361-365.
14. Henley JD, Geary WA, Jackson CL et al. Dedifferentiated acinic cell carcinoma of the parotid gland: a distinct rarely described entity. Hum. Pathol. 1997; 28; 869-873.
15. Nagao T, Gaffey TA, Kay PA et al. Dedifferentiation in low-grade mucoepidermoid carcinoma of the parotid gland. Hum. Pathol. 2003; 34; 1068-1072.
16. Nagao T, Gaffey TA, Serizawa H et al. Dedifferentiated adenoid cystic carcinoma: a clinicopathologic study of 6 cases. Mod. Pathol. 2003; 16; 1265-1272.
17. Piana S, Cavazza A, Pedroni C et al. Dedifferentiated acinic cell carcinoma of the parotid gland with myoepithelial features. Arch. Pathol. Lab. Med. 2002; 126; 1104-1105.
18. Stanley RJ, Weiland LH, Olsen KD et al. Dedifferentiated acinic cell (acinous) carcinoma of the parotid gland. Otolaryngol. Head Neck Surg. 1988; 98; 155-161.
19. Bovee JV, Cleton-Jansen AM, Rosenberg C et al. Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis. J. Pathol. 1999; 189; 454-462.
20. Hameed M, Ulger C, Yasar D et al. Genome profiling of chondrosarcoma using oligonucleotide array-based comparative genomic hybridization. Cancer Genet. Cytogenet. 2009; 192; 56-59.
21. Grote HJ, Schneider-Stock R, Neumann W et al. Mutation of p53 with loss of heterozygosity in the osteosarcomatous component of a dedifferentiated chondrosarcoma. Virchows Arch. 2000; 436; 494-497.
22. He M, Aisner S, Benevenia J et al. Epigenetic alteration of p16INK4a gene in dedifferentiation of liposarcoma. Pathol. Res. Pract. 2009; 205; 386-394.
23. Fukuda T, Ohnishi Y, Watanabe H et al. Dedifferentiated leiomyosarcoma of the intestinal tract: histological, ultrastructural and immunohistochemical examinations. Virchows Arch. 1992; 420; 313-320.
24. Grabellus F, Sheu SY, Schmidt B et al. Recurrent high-grade leiomyosarcoma with heterologous osteosarcomatous differentiation. Virchows Arch. 2006; 448; 85-89.
25. Hashimoto H, Daimaru Y, Tsuneyoshi M et al. Leiomyosarcoma of the external soft tissues. A clinicopathologic, immunohistochemical, and electron microscopic study. Cancer 1986; 57; 2077-2088.
26. Hashimoto H, Daimaru Y, Tsuneyoshi M et al. Soft tissue sarcoma with additional anaplastic components. A clinicopathologic and immunohistochemical study of 27 cases. Cancer 1990; 66; 1578-1589.
27. Nicolas MM, Tamboli P, Gomez JA et al. Pleomorphic and dedifferentiated leiomyosarcoma: clinicopathologic and immunohistochemical study of 41 cases. Hum. Pathol. 2010; 41; 663-671.
28. Oda Y, Miyajima K, Kawaguchi K et al. Pleomorphic leiomyosarcoma: clinicopathologic and immunohistochemical study with special emphasis on its distinction from ordinary leiomyosarcoma and malignant fibrous histiocytoma. Am. J. Surg. Pathol. 2001; 25; 1030-1038.
29. Brady MS, Perino G, Tallini G et al. Malignant mesenchymoma. Cancer 1996; 77; 467-473.
30. Mentzel T, Fletcher CD. Malignant mesenchymomas of soft tissue associated with numerous osteoclast-like giant cells mimicking the so-called giant cell variant of 'malignant fibrous histiocytoma'. Virchows Arch. 1994; 424; 539-545.
31. Newman PL, Fletcher CD. Malignant mesenchymoma. Clinicopathologic analysis of a series with evidence of low-grade behaviour. Am. J. Surg. Pathol. 1991; 15; 607-614.
32. Binh MB, Guillou L, Hostein I et al. Dedifferentiated liposarcomas with divergent myosarcomatous differentiation developed in the internal trunk: a study of 27 cases and comparison to conventional dedifferentiated liposarcomas and leiomyosarcomas. Am. J. Surg. Pathol. 2007; 31; 1557-1566.
33. Dewit L, Albus-Lutter CE, De Jong AS et al. Malignant schwannoma with a rhabdomyoblastic component, a so-called triton tumor. A clinicopathologic study. Cancer 1986; 58; 1350-1356.
34. Ducatman BS, Scheithauer BW. Malignant peripheral nerve sheath tumors with divergent differentiation. Cancer 1984; 54; 1049-1057.