A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 940-946

  Zheng, Yiwen ^a,b   Vagal, Shweta ^a,b   McNamara, Emily ^a,b   Darlington, Cynthia L ^a,b   Smith, Paul F ^a,b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Acoustic trauma; GABA B receptors; L baclofen; Rats; Tinnitus

Indexed keywords

BACLOFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY THRESHOLD; BROADBAND NOISE; CHRONIC TINNITUS; CONDITIONED LICK SUPPRESSION MODEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFECT; DRUG MEGADOSE; EVOKED BRAIN STEM AUDITORY RESPONSE; FREQUENCY DISCRIMINATION; HEARING; INSTRUMENTAL CONDITIONING; LOW DRUG DOSE; MALE; NOISE INJURY; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; RAT; STIMULUS; STIMULUS RESPONSE; SUPPRESSION RATIO; TINNITUS; WHITE NOISE;

ANIMALS; BACLOFEN; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GABA-B RECEPTOR AGONISTS; HEARING LOSS, NOISE-INDUCED; MALE; RATS; RATS, WISTAR; TINNITUS;

EID: 84855941150     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.09.027     Document Type: Article

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