Wound healing following regenerative procedures in furcation degree III defects: Histomorphometric outcomes

Clinical Oral Investigations

Volumn 16, Issue 1, 2012, Pages 239-249

  Gkranias, Nikolaos D ^a   Graziani, Filippo ^a,b   Sculean, Anton ^c   Donos, Nikolaos ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF PISA   (Italy)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Furcation degree III defects; Regenerative procedures; Wound healing

Indexed keywords

CHELATING AGENT; COLLAGEN; EDETIC ACID; ENAMEL MATRIX PROTEINS; ENAMEL PROTEIN; POLYGLACTIN; RESOLUT;

ANIMAL; ARTICLE; ARTIFICIAL MEMBRANE; BIODEGRADABLE IMPLANT; BONE MARROW; CEMENTUM; CLASSIFICATION; COMPARATIVE STUDY; IMAGE PROCESSING; JAW; JAW DISEASE; MACACA FASCICULARIS; MALE; METHODOLOGY; MOLAR TOOTH; PATHOLOGY; PERIODONTAL DISEASE; PERIODONTAL LIGAMENT; PERIODONTICS; PHYSIOLOGY; PLASTIC SURGERY; PREVENTIVE DENTISTRY; TOOTH DEVELOPMENT; TOOTH ROOT; TREATMENT OUTCOME; WOUND HEALING;

ABSORBABLE IMPLANTS; ALVEOLAR PROCESS; ANIMALS; BONE MARROW; CEMENTOGENESIS; CHELATING AGENTS; COLLAGEN; DENTAL CEMENTUM; DENTAL ENAMEL PROTEINS; DENTAL SCALING; EDETIC ACID; FURCATION DEFECTS; GUIDED TISSUE REGENERATION, PERIODONTAL; IMAGE PROCESSING, COMPUTER-ASSISTED; MACACA FASCICULARIS; MALE; MANDIBULAR DISEASES; MEMBRANES, ARTIFICIAL; MOLAR; PERIODONTAL LIGAMENT; POLYGLACTIN 910; ROOT PLANING; SURGICAL FLAPS; TOOTH ROOT; TREATMENT OUTCOME; WOUND HEALING;

EID: 84855923702     PISSN: 14326981     EISSN: 14363771     Source Type: Journal    
DOI: 10.1007/s00784-010-0478-7     Document Type: Article

References (24)

1. Esposito M, Grusovin MG, Coulthard P, Worthington HV (2005) Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects. Cochrane Database Syst Rev (4).
2. Needleman I, Worthington H, Giedrys-Leeper E, Tucker R (2006) Guided tissue regeneration for periodontal infra-bony defects. Cochrane Database Syst Rev 19(2).
3. Jepsen S, Eberhard J, Herrera D, Needleman I (2002) A systematic review of guided tissue regeneration for periodontal furcation defects. What is the effect of guided tissue regeneration compared with surgical debridement in the treatment of furcation defects? J Clin Periodontol 29(Suppl 3): 103-116.
4. Jepsen S, Heinz B, Jepsen K, Arjomand M, Hoffmann T, Richter S, Reich E, Sculean A, Gonzales JR, Bodeker RH, Meyle J (2004) A randomized clinical trial comparing enamel matrix derivative and membrane treatment of buccal Class II furcation involvement in mandibular molars. Part I: study design and results for primary outcomes. J Periodontol 75: 1150-1160.
5. Araújo M, Berglundh T, Lindhe J (1996) The periodontal tissues in healed degree III furcation defects. An experimental study in dogs. J Clin Periodontol 23: 532-541.
6. Araújo MG, Berglundh T, Lindhe J (1997) On the dynamics of periodontal tissue formation in degree III furcation defects. An experimental study in dogs. J Clin Periodontol 24: 738-746.
7. Graziani F, Laurell L, Tonetti M, Gottlow J, Berglundh T (2005) Periodontal wound healing following GTR therapy of dehiscence-type defects in the monkey: short-, medium- and long-term healing. J Clin Periodontol 32: 905-914.
8. Laurell L, Bose M, Graziani F, Tonetti M, Berglundh T (2006) The structure of periodontal tissues formed following guided tissue regeneration therapy of intra-bony defects in the monkey. J Clin Periodontol 33: 596-603.
9. Hammarström L, Heijl L, Gestrelius S (1997) Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins. J Clin Periodontol 24: 669-677.
10. Heijl L (1997) Periodontal regeneration with enamel matrix derivative in one human experimental defect. A case report. J Clin Periodontol 24: 693-696.
11. Araújo MG, Lindhe J (1998) GTR treatment of degree III furcation defects following application of enamel matrix proteins. An experimental study in dogs. J Clin Periodontol 25: 524-530.
12. Sculean A, Donos N, Windisch P, Brecx M, Gera I, Reich E, Karring T (1999) Healing of human intrabony defects following treatment with enamel matrix proteins or guided tissue regeneration. J Periodontal Res 34: 310-322.
13. Sculean A, Donos N, Brecx M, Reich E, Karring T (2000) Treatment of intrabony defects with guided tissue regeneration and enamel-matrix proteins. An experimental study in monkeys. J Clin Periodontol 27: 466-472.
14. Sculean A, Donos N, Brecx M, Karring T, Reich E (2000) Healing of fenestration-type defects following treatment with guided tissue regeneration or enamel matrix proteins. An experimental study in monkeys. Clin Oral Investig 4: 50-56.
15. Donos N, Sculean A, Glavind L, Reich E, Karring T (2003) Wound healing of degree III furcation involvements following guided tissue regeneration and/or Emdogain. A histologic study. J Clin Periodontol 30: 1061-1068.
16. Bosshardt DD, Sculean A, Windisch P, Pjetursson BE, Lang NP (2005) Effects of enamel matrix proteins on tissue formation along the roots of human teeth. J Periodontal Res 40: 158-167.
17. Bosshardt DD, Sculean A, Donos N, Lang NP (2006) Pattern of mineralization after regenerative periodontal therapy with enamel matrix proteins. Eur J Oral Sci 114(Suppl 1): 225-231.
18. Schroeder HE, Münzel-Pedrazzoli S (1973) Correlated morphometric and biochemical analysis of gingival tissue. Morphometric model, tissue sampling and test of stereologic procedures. J Microsc 99(3): 301-329.
19. Gestrelius S, Andersson C, Johansson AC, Persson E, Brodin A, Rydhag L, Hammarstrom L (1997) Formulation of enamel matrix derivative for surface coating. Kinetics and cell colonization. J Clin Periodontol 24: 678-684.
20. Listgarten MA (1972) Electron microscopic study of the junction between surgically denuded root surfaces and regenerated periodontal tissues. J Periodontal Res 7: 68-90.
21. Bosshardt DD, Nanci A (2003) Immunocytochemical characterization of ectopic enamel deposits and cementicles in human teeth. Eur J Oral Sci 111: 51-59.
22. ElDeeb ME, Andreasen JO (1991) Histometric study of the effect of occlusal alteration on periodontal tissue healing after surgical injury. Endod Dent Traumatol 7: 158-163.
23. McGuire MK, Nunn ME (1996) Prognosis versus actual outcome. III. The effectiveness of clinical parameters in accurately predicting tooth survival. J Periodontol 67: 666-674.
24. Donos N, Glavind L, Karring T, Sculean A (2004) Clinical evaluation of an enamel matrix derivative and a bioresorbable membrane in the treatment of degree III mandibular furcation involvement: a series of nine patients. Int J Periodontics Restor Dent 24: 362-369.