Production of baculovirus defective interfering particles during serial passage is delayed by removing transposon target sites in fp25k

Journal of General Virology

Volumn 93, Issue 2, 2012, Pages

  Giri, Lopamudra ^a   Feiss, Michael G ^b   Bonning, Bryony C ^c   Murhammer, David W ^a  

^a IA United States   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ARTICLE; AUTOGRAPHA CALIFORNICA; BACULOVIRUS; CONTROLLED STUDY; DEFECTIVE VIRUS; FP25K GENE; GENE INSERTION; GENOME SIZE; NONHUMAN; PHENOTYPE; POLYHEDROSIS VIRUS; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; TRANSPOSON; VIRUS CULTURE; VIRUS GENE; VIRUS GENOME; VIRUS PARTICLE; VIRUS RECOMBINANT; ANIMAL; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; LEPIDOPTERA; ULTRASTRUCTURE; VIROLOGY; VIRULENCE;

AUTOGRAPHA CALIFORNICA MNPV; AUTOGRAPHA CALIFORNICA NUCLEOPOLYHEDROVIRUS; HEXAPODA;

ANIMALS; DEFECTIVE VIRUSES; DNA TRANSPOSABLE ELEMENTS; LEPIDOPTERA; NUCLEOPOLYHEDROVIRUS; SEQUENCE DELETION; SERIAL PASSAGE; VIRULENCE;

EID: 84855923049     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.036566-0     Document Type: Article

References (41)

1. Ayres, M. D., Howard, S. C., Kuzio, J., Lopez-Ferber, M. & Possee, R. D. (1994). The complete DNA sequence of Autographa californica nuclear polyhedrosis virus. Virology 202, 586-605.
2. Black, B. C., Brennan, L. A., Dierks, P. M. & Gard, I. E. (1997). Commercialization of baculoviral insecticides. In The Baculoviruses, pp. 341-388. Edited by L. K. Miller. New York: Plenum Press.
3. Burand, J. P. & Summers, M. D. (1982). Alteration of Autographa californica nuclear polyhedrosis virus DNA upon serial passage in cell culture. Virology 119, 223-229.
4. Burand, J. P., Wood, H. A. & Summers, M. D. (1983). Defective particles from a persistent baculovirus infection in Trichoplusia ni tissue culture cells. J Gen Virol 64, 391-398.
5. Carstens, E. B. (1987). Identification and nucleotide sequence of the regions of Autographa californica nuclear polyhedrosis virus genome carrying insertion elements derived from Spodoptera frugiperda. Virology 161, 8-17.
6. Cochran, M. A. & Faulkner, P. (1983). Location of homologous DNA sequences intercepted at five regions in the baculovirus AcMNPV genome. J Gen Virol 45, 961-970.
7. DuPont A (1996). Notification to conduct small-scale field testing of a genetically altered baculovirus. EPA No. 352-NMP-4.
8. Fraser, M. J., Smith, G. E. & Summers, M. D. (1983). Acquisition of host cell DNA sequences by baculoviruses: relationship between host DNA insertions and FP mutants of Autographa californica and Galleria mellonella nuclear polyhedrosis viruses. J Virol 47, 287-300.
9. Gard, I. E. (1997). Field testing a genetically modified baculovirus. In Brighton Crop Protection Conference Symposium Proceedings No. 68: Microbial Insecticides: Novelty or Necessity?, pp. 101-114.
10. Giri, L., Li, H., Sandgren, D., Feiss, M. G., Roller, R., Bonning, B. C. & Murhammer, D. W. (2010). Removal of transposon target sites from the Autographa californica multiple nucleopolyhedrovirus fp25k gene delays, but does not prevent, accumulation of the few polyhedra phenotype. J Gen Virol 91, 3053-3064.
11. Guarino, L. A., Gonzalez, M. A. & Summers, M. D. (1986). Complete sequence and enhancer function of the homologous DNA regions of Autographa californica nuclear polyhedrosis virus. J Virol 60, 224-229.
12. Harrison, R. L. & Summers, M. D. (1995). Mutations in the Autographa californica multinucleocapsid nuclear polyhedrosis virus 25 kDa protein gene result in reduced virion occlusion, altered intranuclear envelopment and enhanced virus production. J Gen Virol 76, 1451-1459.
13. Jarvis, D. L. & Garcia, A., Jr (1994). Long-term stability of baculoviruses stored under various conditions. Biotechniques 16, 508-513.
14. Kelly, B. J., King, L. A. & Possee, R. D. (2007). Introduction to baculovirus molecular biology. In Baculovirus and Insect Cell Expression Protocols, pp. 25-53. Edited by D. W. Murhammer. Totowa, New Jersey: Humana Press
15. Kompier, R., Tramper, J. & Vlak, J. M. (1988). A continuous process for the production of baculovirus using insect-cell cultures. Biotechnol Lett 10, 849-854.
16. Kool, M., Voncken, J. W., van Lier, F. L. J., Tramper, J. & Vlak, J. M. (1991). Detection and analysis of Autographa californica nuclear polyhedrosis virus mutants with defective interfering properties. Virology 183, 739-746.
17. Krell, P. J. (1996). Passage effect of virus infection in insect cells. Cytotechnology 20, 125-137.
18. Kumar, S. & Miller, L. K. (1987). Effects of serial passage of Autographa californica nuclear polyhedrosis virus in cell culture. Virus Res 7, 335-349.
19. Lee, H. Y. & Krell, P. J. (1992). Generation and analysis of defective genomes of Autographa californica nuclear polyhedrosis virus. J Virol 66, 4339-4347.
20. Miller, D. W. & Miller, L. K. (1982). A virus mutant with an insertion of a copia-like transposable element. Nature 299, 562-564.
21. Moscardi, F. (1999). Assessment of the application of baculoviruses for control of Lepidoptera. Annu Rev Entomol 44, 257-289.
22. Murhammer, D. W. (1996). Use of viral insecticides for pest control and production in cell culture. Appl Biochem Biotechnol 59, 199-220.
23. O'Reilly, D. R., Passarelli, A. L., Goldman, I. F. & Miller, L. K. (1990). Characterization of the DA26 gene in a hypervariable region of the Autographa californica nuclear polyhedrosis virus genome. J Gen Virol 71, 1029-1037.
24. Parekh, D. (2008). Development and Scale-up of Protein Production Using the Baculovirus Expression System. Boston, MA: Process Sciences, Diosynth Biotechnology, Baculovirus Technology.
25. Pfaller, M. A., Hollis, R. J. & Sader, H. S. (1994). Chromosomal restriction fragment analysis by pulsed field gel electrophoresis. In Clinical Microbiology Procedures Handbook, Suppl. 1, pp. 10.5c.1-10.5c12. Edited by H. D. Isenberg. Washington, DC: American Society for Microbiology.
26. Pijlman, G. P., van den Born, E., Martens, D. E. & Vlak, J. M. (2001). Autographa californica baculoviruses with large genomic deletions are rapidly generated in infected insect cells. Virology 283, 132-138.
27. Pijlman, G. P., Dortmans, J. C., Vermeesch, A. M. G., Yang, K., Martens, D. E., Goldbach, R. W. & Vlak, J. M. (2002). Pivotal role of the non-hr origin of DNA replication in the genesis of defective interfering baculoviruses. J Virol 76, 5605-5611.
28. Pijlman, G. P., van Schijndel, J. E. & Vlak, J. M. (2003). Spontaneous excision of BAC vector sequences from bacmid-derived baculovirus expression vectors upon passage in insect cells. J Gen Virol 84, 2669-2678.
29. Pijlman, G. P., de Vrij, J., van den End, F. J., Vlak, J. M. & Martens, D. E. (2004). Evaluation of baculovirus expression vectors with enhanced stability in continuous cascaded insect-cell bioreactors. Biotechnol Bioeng 87, 743-753.
30. Potter, K. N. & Miller, L. K. (1980). Correlating genetic mutation of a baculovirus with the physical map of the DNA genome. ICN-UCLA Symp Mol Cell Biol 18, 71-80.
31. Slansky, J. (2008). Generation of Antigen-specific Antitumor Immunity Using Insect Cells Infected with Recombinant Baculoviruses. Boston, MA: Health Sciences Center, University of Colorado, Baculovirus Technology.
32. Tramper, J. & Vlak, J. M. (1986). Some engineering and economic aspects of continuous cultivation of insect cells for the production of baculoviruses. Ann N Y Acad Sci 469, 279-288.
33. Vanarsdall, A. L., Mikhailov, V. S. & Rohrmann, G. F. (2007). Characterization of a baculovirus lacking the DBP (DNA-binding protein) gene. Virology 364, 475-485.
34. van Hulten, M. C. W., Witteveldt, J., Peters, S., Kloosterboer, N., Tarchini, R., Fiers, M., Sandbrink, H., Lankhorst, R. K. & Vlak, J. M. (2001). The white spot syndrome virus DNA genome sequence. Virology 286, 7-22.
35. van Lier, F. L. J., van den End, E. J., de Gooijer, C. D., Vlak, J. M. & Tramper, J. (1990). Continuous production of baculovirus in a cascade of insect-cell reactors. Appl Microbiol Biotechnol 33, 43-47.
36. van Lier, F. L. J., van der Meijs, W. C., Grobben, N. G., Olie, R. A., Vlak, J. M. & Tramper, J. (1992). Continuous b-galactosidase production with a recombinant baculovirus insect-cell system in bioreactors. J Biotechnol 22, 291-298.
37. van Lier, F. L. J., van Duijnhoven, G. C., de Vaan, M. M., Vlak, J. M. & Tramper, J. (1994). Continuous b-galactosidase production in insect cells with a p10 gene based baculovirus vector in a two-stage bioreactor system. Biotechnol Prog 10, 60-64.
38. Vaughn, J. L., Goodwin, R. H., Tompkins, G. J. & McCawley, P. (1977). The establishment of two cell lines from the insect Spodoptera frugiperda (Lepidoptera; Noctuidae). In Vitro 13, 213-217.
39. Vlak, J. M. & Smith, G. E. (1982). Orientation of the genome of Autographa californica nuclear polyhedrosis virus: a proposal. J Virol 41, 1118-1121.
40. Wickham, T. J., Davis, T., Granados, R. R., Hammer, D. A., Shuler, M. L. & Wood, H. A. (1991). Baculovirus defective interfering particles are responsible for variations in recombinant protein production as a function of multiplicity of infection. Biotechnol Lett 13, 483-488.
41. Zwart, M. P., Erro, E., van Oers, M. M., de Visser, J. A. G. M. & Vlak, J. M. (2008). Lowmultiplicity of infection in vivo results in purifying selection against baculovirus deletion mutants. J Gen Virol 89, 1220-1224.