Spontaneous graft versus host disease occurring in a patient with multiple myeloma after autologous stem cell transplant

American Journal of Hematology

Volumn 87, Issue 2, 2012, Pages 219-221

  Fidler, Christian ^a   Klumpp, Thomas ^a   Mangan, Kenneth ^a   Martin, Maryellen ^a   Sharma, Manish ^a   Emmons, Robert ^a   Lu, Meina ^a   Kropf, Patricia ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BORTEZOMIB; CYCLOPHOSPHAMIDE; DEXAMETHASONE; GRANULOCYTE COLONY STIMULATING FACTOR; HYPERTENSIVE FACTOR; MELPHALAN; METHYLPREDNISOLONE SODIUM SUCCINATE; METRONIDAZOLE; PREDNISONE; PREGABALIN; TACROLIMUS; VANCOMYCIN;

ADULT; ANOREXIA; ANTIBIOTIC THERAPY; AUTOLOGOUS STEM CELL TRANSPLANTATION; CASE REPORT; CLOSTRIDIUM DIFFICILE INFECTION; DEATH; DIARRHEA; DISEASE SEVERITY; DRUG DOSE INCREASE; DRUG MEGADOSE; ENGRAFTMENT; EOSINOPHILIA; ERYTHEMA; ERYTHRODERMA; FEMALE; FEVER; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTUBATION; LETTER; MUCOSA INFLAMMATION; MULTIPLE MYELOMA; NAUSEA; NEUROPATHY; PANCYTOPENIA; PRIORITY JOURNAL; RASH; SEPSIS; SKIN BIOPSY; SKIN EXFOLIATION; SKIN ULCER; TREATMENT RESPONSE;

FATAL OUTCOME; FEMALE; GASTROINTESTINAL TRACT; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MIDDLE AGED; MULTIPLE MYELOMA; SKIN; TRANSPLANTATION, AUTOLOGOUS;

EID: 84855912585     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.22227     Document Type: Letter

References (13)

1. Jones RJ, Vogelsang GB, Jones RJ, et al. Induction of graft versus host disease after autologous bone marrow transplantation. Lancet 1989; 1: 754-757.
2. Drobyski WR, Hari P, Keever-Taylor C, et al. Severe autologous GVHD after hematopoietic progenitor cell transplantation for multiple myeloma. Bone Marrow Transplant 2009; 43: 169-177.
3. Lazarus, HM, Sommers SR, Arfons LM, et al. Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: Flow cytometric analysis of hematopoietic progenitor cell grafts. Biol Blood Marrow Transplant 2011; 17: 970-978.
4. Yeager AM, Vogelsang GB, Jones RJ, et al. Induction of cutaneous graft versus host disease by administration of cyclosporine to patients undergoing autologous bone marrow transplantation for acute myeloid leukemia. Blood 1992; 80: 2948-2950.
5. Giralt S, Weber D, Colome M, et al. Phase I trial of cyclosporine-induced autologous graft versus host disease in patients with multiple myeloma undergoing high dose chemotherapy with autologous stem cell rescue. J Clin Oncol 1997; 15: 667-673.
6. Fischer AC, Ruvolo PP, Burt R, et al. Characterization of the autoreactive T-cell repetoire in cyclosporine-induced syngeneic graft versus host disease, a highly conserved repertoire mediates autoaggression. J Immunol 1995; 154: 3713-3725.
7. Hess AD, Thoburn CJ, Chen W, Horwitz LR. Complexity of effector mechanisms in cyclosporine-induced syngeneic graft versus host disease. Biol Blood Marrow Transplant 2000; 6: 13-24.
8. Holmberg L, Kikuchi K, Gooley TA, et al. Gastrointestinal graft versus host disease in recipients of autologous hematopoietic stem cells: Incidence, risk factors and outcome. Biol Blood Marrow Transplant 2006; 12: 226-234
9. Tzung S-P, Hackman RC, Hockenberry DM, et al. Lymphocytic gastritis resembling graft versus host disease following autologous hematopoietic cell transplantation. Biol Blood Marrow Transplant 1998; 4: 43-48.
10. Saunders MD, Shulman HM, Murakami CS, et al. Bile duct apoptosis and cholestasis resembling acute graft versus host disease after autologous hematopoietic cell transplantation. Am J Surg Pathol 2000; 24: 1004-1008.
11. Hood AF, Vogelsang GB, Black LP, et al. Acute graft versus host disease: Development following autologous and syngeneic bone marrow transplantation. Arch Dermatol 1987; 123: 745-750.
12. Adams J, Palombella VJ, Sausville EA, et al. Proteasome inhibitors: A novel class of potent and effective antitumor agents. Cancer Res 1999; 59: 2615-2622.
13. Stuart L, Hughes J. Apoptosis and autoimmunity. Nephrol Dial Transplant 2002; 17: 697-700.