The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities

Biochemical Journal

Volumn 441, Issue 3, 2012, Pages 803-812

  Brook, Matthew ^a,b   McCracken, Lora ^a,d   Reddington, James P ^b   Lu, Zhi Liang ^a,e   Morrice, Nicholas A ^c,f   Gray, Nicola K ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d SCOTTISH NATIONAL BLOOD TRANSFUSION SERVICE   (United Kingdom)

^e XI AN JIAOTONG LIVERPOOL UNIVERSITY   (China)

^f BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

mRNA translation; Poly(A) binding protein (PABP); Poly(A) binding protein interacting motif 2 (PAM2) poly(A) binding protein C terminal domain (PABC) interaction; Post transcriptional control; Post translational modification; RNA binding protein

Indexed keywords

ARGININE; ASPARTIC ACID; CYTOPLASM PROTEIN; GLUTAMIC ACID; LYSINE; MESSENGER RNA; POLYADENYLIC ACID BINDING PROTEIN; RIBONUCLEOPROTEIN;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL CYCLE; CONTROLLED STUDY; CYTOPLASM; EUKARYOTE; HUMAN; HUMAN CELL; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

ANIMALS; ARGININE; CELLS, CULTURED; HELA CELLS; HUMANS; KINETICS; METHYLATION; MICE; MODELS, MOLECULAR; POLY(A)-BINDING PROTEIN I; PROTEIN METHYLTRANSFERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EUKARYOTA;

EID: 84855911694     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111474     Document Type: Article

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