Lacosamide use in refractory idiopathic primary generalized epilepsy

Epilepsy and Behavior

Volumn 23, Issue 1, 2012, Pages 79-80

  Zangaladze, Andro ^a   Skidmore, Christopher ^b  

^a Virtua Health   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Idiopathic primary generalized epilepsy; Juvenile myoclonic epilepsy; Lacosamide

Indexed keywords

CLONAZEPAM; ETIRACETAM; HARKOSERIDE; LAMOTRIGINE; OXCARBAZEPINE; TOPIRAMATE; VALPROIC ACID; ZONISAMIDE;

ADD ON THERAPY; ADJUVANT THERAPY; ADULT; ANTICONVULSANT THERAPY; ARTICLE; CASE REPORT; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAPHY; ELECTROGRAPHY; EPILEPTIC DISCHARGE; FEMALE; HUMAN; MYOCLONUS SEIZURE; REMISSION; TONIC CLONIC SEIZURE; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ACETAMIDES; ANTICONVULSANTS; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; HUMANS; YOUNG ADULT;

EID: 84855905606     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2011.10.023     Document Type: Article

References (7)

1. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989, 30:389-399.
2. Marson A.G., Al-Kharusi A.M., Alwaidh M., et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet 2007, 369:1016-1026.
3. Berkovic S.F., Knowlton R.C., Leroy R.F., Schiemann J., Falter U. for the LevetiracetamN01057 Study Group. Placebo controlled study of levetiracetam in idiopathic generalized epilepsy. Neurology 2007, 69:1751-1760.
4. Cossette P. Channelopathies and juvenile myoclonic epilepsy. Epilepsia 2010, 51(Suppl. 1):30-32.
5. Scheffer I.E., Berkovic S.F. Generalized epilepsy with febrile seizures plus: a genetic disorder with heterogenous phenotypes. Brain 1997, 120:479-490.
6. Beyreuther B.K., Freitag J., Heers C., Krebsfänger N., Scharfenecker U., Stöhr T. Lacosamide: a review of preclinical properties. CNS Drug Rev 2007, 13:21-42.
7. Montegazza M., Curia G., Giuseppe B., Ragsdale D., Avoli M. Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders. Lancet Neurol 2010, 9:413-424.