Risk factors, clinical features, and outcomes of toxoplasmosis in solid-organ transplant recipients: A matched case-control study

Clinical Infectious Diseases

Volumn 54, Issue 3, 2012, Pages 355-361

  Fernàndez Sabé, Núria ^a   Cervera, Carlos ^b   Fariñas, M Carmen ^c   Bodro, Marta ^a   Muñoz, Patricia ^d   Gurguí, Mercè ^e   Torre Cisneros, Julián ^f   Martín Dávila, Pilar ^g   Noblejas, Ana ^h   Len, Óscar ⁱ   García Reyne, Ana ^j   Del Pozo, José Luis ^k   Carratalà, Jordi ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^d HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^e UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^f HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^g HOSPITAL RAMÓN Y CAJAL   (Spain)

^h HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

ⁱ HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^j HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^k UNIVERSITY CLINIC OF NAVARRA   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE; CYCLOSPORIN; METHYLPREDNISOLONE; PREDNISONE; PYRIMETHAMINE; TACROLIMUS;

ADULT; AGED; ARTICLE; AUTOPSY; BRAIN ABSCESS; CASE CONTROL STUDY; CHORIORETINITIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; CRUDE MORTALITY RATE; DYSPNEA; FACTUAL DATABASE; FEMALE; FEVER; GRAFT RECIPIENT; GRAFT VERSUS HOST REACTION; HEADACHE; HEART TRANSPLANTATION; HISTOPATHOLOGY; HUMAN; IMMUNOPROPHYLAXIS; INFECTION RISK; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; LYMPHADENOPATHY; MALE; MENINGITIS; MORTALITY; MULTICENTER STUDY; MYOCARDITIS; ORGAN TRANSPLANTATION; PATIENT IDENTIFICATION; PNEUMONIA; POLYMERASE CHAIN REACTION; PRIMARY INFECTION; PRIORITY JOURNAL; RISK FACTOR; SEROCONVERSION; SEROLOGY; SOLID ORGAN TRANSPLANT; SPAIN; TOXOPLASMOSIS; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; ANTI-INFECTIVE AGENTS; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; ORGAN TRANSPLANTATION; PREDNISONE; RISK FACTORS; TOXOPLASMOSIS; YOUNG ADULT;

EID: 84855897466     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cir806     Document Type: Article

References (35)

1. Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med 2007;357:2601-14. (Pubitemid 350294226)
2. De Ory Manchòn F. Seroepidemiological surveys of non vaccinepreventable diseases and their interest in public health. Rev Esp Salud Publica 2009;83:645-57.
3. Boto de los Bueis A, Vega Alemàn D, Gàlvez Acebal J, Merino Muñoz D, Creagh Cerquera R, Pujol de la Llave E. [Prevalence of latent toxoplasma infection in HIV infection patients]. An Med Interna 1998;15:298-300.
4. Innes EA. A brief history and overview of Toxoplasma gondii. Zoonoses Public Health 2010;57:1-7.
5. Morris MI, Fischer SA, Ison MG. Infections transmitted by transplantation. Infect Dis Clin North Am 2010;24:497-514.
6. Rogers NM, Peh CA, Faull R, Pannell M, Cooper J, Russ GR. Transmission of toxoplasmosis in two renal allograft recipients receiving an organ from the same donor. Transpl Infect Dis 2008;10:71-4. (Pubitemid 351171317)
7. Gallino A, Maggiorini M, Kiowski W, et al. Toxoplasmosis in heart transplant recipients. Eur J Clin Microbiol Infect Dis 1996;15:389-93. (Pubitemid 26181638)
8. Orr KE, Gould FK, Short G, et al. Outcome of Toxoplasma gondii mismatches in heart transplant recipients over a period of 8 years. J Infect 1994;29:249-53. (Pubitemid 24365180)
9. Wreghitt TG, Hakim M, Gray JJ, et al. Toxoplasmosis in heart and heart and lung transplant recipients. J Clin Pathol 1989;42:194-9. (Pubitemid 19048478)
10. McGregor CG, Fleck DG, Nagington J, Stovin PG, Cory-Pearce R, English TA. Disseminated toxoplasmosis in cardiac transplantation. J Clin Pathol 1984;37:74-7. (Pubitemid 14218068)
11. Renoult E, Biava MF, Hulin C, Frimat L, Hestin D, Kessler M. Transmission of toxoplasmosis by renal transplant: a report of four cases. Transpl Proc 1996;28:181-3. (Pubitemid 26073692)
12. Luft BJ, Naot Y, Araujo FG, Stinson EB, Remington JS. Primary and reactivated toxoplasma infection in patients with cardiac transplants. Clinical spectrum and problems in diagnosis in a defined population. Ann Intern Med 1983;99:27-31. (Pubitemid 13066653)
13. Campbell AL, Goldberg CL, Magid MS, Gondolesi G, Rumbo C, Herold BC. First case of toxoplasmosis following small bowel transplantation and systematic review of tissue-invasive toxoplasmosis following noncardiac solid organ transplantation. Transplantation 2006;81:408-17. (Pubitemid 43255727)
14. Martina MN, Cervera C, Esforzado N, et al. Toxoplasma gondii primary infection in renal transplant recipients. Two case reports and literature review. Transpl Int 2011;24:e6-12.
15. Humar A, Michaels M. AST ID Working Group on Infectious Disease Monitoring. American Society of Transplantation recommendations for screening, monitoring and reporting of infectious complications in immunosuppression trials in recipients of organ transplantation. Am J Transplant 2006;6:262-74. (Pubitemid 43382161)
16. Schoorndermark-van de Ven E, Galama J, Kraaijeveld C, van Druten J, Meuwissen J, Melchers W. Value of the polymerase chain reaction for the detection of Toxoplasma gondii in cerebrospinal fluid from patients with AIDS. Clin Infect Dis 1993;16:661-6. (Pubitemid 23136565)
17. Hosmer DW, Lemeshow S. Logistic regression: variable selection. In: Hosmer DW, Lemeshow S, eds. Applied logistic regression. 2nd ed. New York, NY: John Wiley & Sons, 2000.
18. Muñoz P, Arencibia J, Rodrìguez C, et al. Trimethoprim-sulfamethoxazole as toxoplasmosis prophylaxis for heart transplant recipients. Clin Infect Dis 2003;36:932-3. (Pubitemid 36403529)
19. Gourishankar S, Doucette K, Fenton J, et al. The use of donor and recipient screening for toxoplasma in the era of universal trimethoprim sulfamethoxazole prophylaxis. Transplantation 2008;85:980-5. (Pubitemid 351543161)
20. Fishman JA. Prevention of infection caused by Pneumocystis carinii in transplant recipients. Clin Infect Dis 2001;33:1397-405. (Pubitemid 32955195)
21. Fernàndez-Sabè N, Cervera C, Lòpez-Medrano F, et al. Risk factors, clinical features, and outcomes of listeriosis in solid-organ transplant recipients: a matched case-control study. Clin Infect Dis 2009;49:1153-9.
22. Baden LR, Katz JT, Franck L, et al. Successful toxoplasmosis prophylaxis after orthotopic cardiac transplantation with trimethoprimsulfamethoxazole. Transplantation 2003;75:339-43. (Pubitemid 36222959)
23. Baran DA, Alwarshetty MM, Alvi S, et al. Is toxoplasmosis prophylaxis necessary in cardiac transplantation? Long-term follow-up at two transplant centers. J Heart Lung Transpl 2006;25:1380-2. (Pubitemid 44692500)
24. Keogh A, Macdonald P, Richens D, Harvison A, Spratt P. Mini-dose trimethoprim with sulphamethoxazole prevents pneumocystis and toxoplasmosis infections after heart transplantation. Transpl Proc 1992;24:2263.
25. Renoult E, Georges E, Biava MF, et al. Toxoplasmosis in kidney transplant recipients: report of six cases and review. Clin Infect Dis 1997;24:625-34. (Pubitemid 27143556)
26. Manz T, Grotz W, Orszagh M, Volk B, Kirste G, Neumann HP. A patient with neurological deficits and seizures after renal transplantation. Nephrol Dial Transpl 2001;16:631-3. (Pubitemid 32229304)
27. Singh N, Husain S. Infections of the central nervous system in transplant recipients. Transpl Infect Dis 2000;2:101-11.
28. Barcàn LA, Dallurzo ML, Clara LO, et al. Toxoplasma gondii pneumonia in liver transplantation: survival after a severe case of reactivation. Transpl Infect Dis 2002;4:93-6.
29. Singh N, Gayowski T, Marino IR. Toxoplasma gondii pneumonitis in a liver transplant recipient: implications for diagnosis. Liver Transpl Surg 1996;2:299-300. (Pubitemid 26243441)
30. Patel R. Disseminated toxoplasmosis after liver transplantation. Clin Infect Dis 1999;29:705-6.
31. Lappalainen M, Jokiranta TS, Halme L, et al. Disseminated toxoplasmosis after liver transplantation: case report and review. Clin Infect Dis 1998;27:1327-8. (Pubitemid 29242497)
32. Kotton CN, Lattes R. AST Infectious Diseases Community of Practice. Parasitic infections in solid organ transplant recipients. Am J Transpl 2009;9(Suppl 4): S234-51.
33. Martino R, Bretagne S, Einsele H, et al. Early detection of Toxoplasma infection by molecular monitoring of Toxoplasma gondii in peripheral blood samples after allogenic stem cell transplantation. Clin Infect Dis 2005;40:67-78. (Pubitemid 40053461)
34. Patrat-Delon S, Gangneux JP, Lavouè S, et al. Correlation of parasite load determined by quantitative PCR to clinical outcome in a heart transplant patient with disseminated toxoplasmosis. J Clin Microbiol 2010;48:2541-5.
35. Botterel F, Ichai P, Feray C, et al. Disseminated toxoplasmosis, resulting from infection of allograft, after orthotopic liver transplantation: usefulness of quantitative PCR. J Clin Microbiol 2002;40:1648-50. (Pubitemid 34493133)