(-)-Epigallocatechin-3-gallate protects against neuronal cell death and improves cerebral function after traumatic brain injury in rats

NeuroMolecular Medicine

Volumn 13, Issue 4, 2011, Pages 300-309

  Itoh, Tatsuki ^a   Imano, Motohiro ^a   Nishida, Shozo ^a   Tsubaki, Masahiro ^a   Hashimoto, Shigeo ^b   Ito, Akihiko ^a   Satou, Takao ^a,c  

^a KINKI UNIVERSITY   (Japan)

^b PL Hospital   (Japan)

^c KINDAI UNIVERSITY HOSPITAL   (Japan)

Author keywords

Apoptosis; Epigallocatechin; Neuroprotection; Oxidative stress; Traumatic brain injury

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; EPIGALLOCATECHIN GALLATE; MALONALDEHYDE; NEURON SPECIFIC NUCLEAR PROTEIN; SINGLE STRANDED DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DYSFUNCTION; BRAIN FUNCTION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; MICROMORPHOLOGY; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TRAUMATIC BRAIN INJURY; TREATMENT DURATION;

ANIMALS; APOPTOSIS; BRAIN INJURIES; CATECHIN; CEREBRAL CORTEX; COGNITION DISORDERS; DNA, SINGLE-STRANDED; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; TEA;

RATTUS; RATTUS NORVEGICUS;

EID: 84855894108     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-011-8162-x     Document Type: Article

References (32)

1. Ates, O., Cayli, S., Altinoz, E., Gurses, I., Yucel, N., Sener, M., et al. (2007). Neuroprotection by resveratrol against traumatic brain injury in rats. Molecular and Cellular Biochemistry, 294, 137-144. (Pubitemid 46188894)
2. Buffo, A., Rolando, C., & Ceruti, S. (2010). Astrocytes in the damaged brain: Molecular and cellular insights into their reactive response and healing potential. Biochemical Pharmacology, 79, 77-89.
3. Chan, P. H., Fishman, R. A., Longar, S., Chen, S., & Yu, A. (1985). Cellular and molecular effects of polyunsaturated fatty acids in brain ischemia and injury. Progress in Brain Research, 63, 227-235.
4. Chirumamilla, S., Sun, D., Bullock, M. R., & Colello, R. J. (2002). Traumatic brain injury induced cell proliferation in the adult mammalian central nervous system. Journal of Neurotrauma, 19, 693-703. (Pubitemid 34761333)
5. Gage, F. H. (2000). Mammalian neural stem cells. Science, 287, 1433-1438. (Pubitemid 30127128)
6. Hall, E. D., & Braughler, J. M. (1989). Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radical Biology and Medicine, 6, 303-313. (Pubitemid 19076496)
7. Hong, J. T., Ryu, S. R., Kim, H. J., Lee, J. K., Lee, S. H., Kim, D. B., et al. (2000). Neuroprotective effect of green tea extract in experimental ischemia-reperfusion brain injury. Brain Research Bulletin, 53, 743-749. (Pubitemid 32120278)
8. Itoh, T., Imano, M., Nishida, S., Tsubaki, M., Hashimoto, S., Ito, A., et al. (2011). Exercise inhibits neuronal apoptosis and improves cerebral function following rat traumatic brain injury. Journal of Neural Transm, 118, 1263-1272.
9. Itoh, T., Satou, T., Hashimoto, S., & Ito, H. (2005). Isolation of neural stem cells from damaged rat cerebral cortex after TBI. Neuroreport, 16, 1687-1691. (Pubitemid 41805804)
10. Itoh, T., Satou, T., Hashimoto, S., & Ito, H. (2007). Immature and mature neurons coexist among glial scars after rat traumatic brain injury. Neurological Research, 29, 734-742. (Pubitemid 350086074)
11. Itoh, T., Satou, T., Nishida, S., Tsubaki, M., Hashimoto, S., & Ito, H. (2009a). Improvement of cerebral function by anti-amyloid precursor protein antibody infusion after traumatic brain injury in rats. Molecular and Cellular Biochemistry, 324, 191-199.
12. Itoh, T., Satou, T., Nishida, S., Tsubaki, M., Hashimoto, S., & Ito, H. (2009b). The novel free radical scavenger, edaravone, increases neural stem cell number around the area of damage following rat traumatic brain injury. Neurotoxicity Research, 16, 378-389.
13. Itoh, T., Satou, T., Nishida, S., Tsubaki, M., Imano, M., Hashimoto, S., et al. (2010). Edaravone protects against apoptotic neuronal cell death and improves cerebral function after traumatic brain injury in rats. Neurochemical Research, 35, 348-355.
14. Jang, S., Jeong, H. S., Park, J. S., Kim, Y. S., Jin, C. Y., Seol, M. B., et al. (2010). Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition. Brain Research, 1313, 25-33.
15. Kawamata, T., Katayama, Y., Hovda, D. A., Yoshino, A., & Becker, D. P. (1995). Lactate accumulation following concussive brain injury: The role of ionic fluxes induced by excitatory amino acids. Brain Research, 674, 196-204.
16. Kontos, H. A. (1985). George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury. Circulation Research, 57, 508-516. (Pubitemid 16233117)
17. Lee, H., Bae, J. H., & Lee, S. R. (2004). Protective effect of green tea polyphenol EGCG against neuronal damage and brain edema after unilateral cerebral ischemia in gerbils. Journal of Neuroscience Research, 77, 892-900. (Pubitemid 39187072)
18. Lee, S. Y., Kim, C. Y., Lee, J. J., Jung, J. G., & Lee, S. R. (2003). Effects of delayed administration of (-)-epigallocatechin gallate, a green tea polyphenol on the changes in polyamine levels and neuronal damage after transient forebrain ischemia in gerbils. Brain Research Bulletin, 61, 399-406.
19. Lee, E. J., Lee, M. Y., Chen, H. Y., Hsu, Y. S., Wu, T. S., Chen, S. T., et al. (2005). Melatonin attenuates gray and white matter damage in a mouse model of transient focal cerebral ischemia. Journal of Pineal Research, 38, 42-52.
20. Loren, D. J., Seeram, N. P., Schulman, R. N., & Holtzman, D. M. (2005). Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxicischemic brain injury. Pediatric Research, 57, 858-864. (Pubitemid 40727118)
21. McGraw, J., Hiebert, G. W., & Steeves, J. D. (2001). Modulating astrogliosis after neurotrauma. Journal of Neuroscience Research, 63, 109-115. (Pubitemid 32041861)
22. Park, J.W., Jang, Y.H., Kim, J.M., Lee, H., Park, W.K., Lim, M.B., et al. (2009). Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia. Journal of Neuroscience Research, 87, 567-575.
23. Rice, A. C., Khaldi, A., Harvey, H. B., Salman, N. J., White, F., Fillmore, H., et al. (2003). Proliferation and neuronal differentiation of mitotically active cells following traumatic brain injury. Experimental Neurology, 183, 406-417. (Pubitemid 37205082)
24. Sakurai, M., Nagata, T., Abe, K., Horinouchi, T., Itoyama, Y., & Tabayashi, K. (2003). Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits. Journal of Vascular Surgery, 37, 446-452. (Pubitemid 36236926)
25. Sugawara, T., Noshita, N., Lewen, A., Gasche, Y., Ferrand-Drake, M., Fujimura, M., et al. (2002). Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. Journal of Neuroscience, 22, 209-217. (Pubitemid 34036536)
26. Wang, X., Karlsson, J. O., Zhu, C., Bahr, B. A., Hagberg, H., & Blomgren, K. (2001). Caspase-3 activation after neonatal rat cerebral hypoxia-ischemia. Biology of the Neonate, 79, 172-179. (Pubitemid 32247082)
27. Weinreb, O., Amit, T., Mandel, S., & Youdim, M. B. (2009). Neuroprotective molecular mechanisms of (-)-epigallocatechin-3-gallate: A reflective outcome of its antioxidant, iron chelating and neuritogenic properties. Genes & Nutrition, 4, 283-296.
28. Weissman, L., de Souza-Pinto, N. C., Stevnsner, T., & Bohr, V. A. (2007). DNA repair, mitochondria, and neurodegeneration. Neuroscience, 145, 1318-1329. (Pubitemid 46602727)
29. Won, M. H., Kang, T., Park, S., Jeon, G., Kim, Y., Seo, J. H., et al. (2001). The alterations of N-Methyl-D-aspartate receptor expressions and oxidative DNA damage in the CA1 area at the early time after ischemia-reperfusion insult. Neuroscience Letters, 301, 139-142. (Pubitemid 32206705)
30. Xiong, Y., Gu, Q., Peterson, P. L., Muizelaar, J. P., & Lee, C. P. (1997). Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. Journal of Neurotrauma, 14, 23-34. (Pubitemid 27100278)
31. Xiong, Y., Mahmood, A., Lu, D., Qu, C., Kazmi, H., Goussev, A., et al. (2008). Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system. Brain Research, 1230, 247-257.
32. Yu, J., Jia, Y., Guo, Y., Chang, G., Duan, W., Sun, M., et al. (2010). Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level. FEBS Letter, 584, 2921-2925.