Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption

Oral Oncology

Volumn 48, Issue 1, 2012, Pages 40-48

  Hwang, Young Sun ^a   Lee, Sun Kyoung ^a   Park, Kwang Kyun ^a   Chung, Won Yoon ^a  

^a Yonsei University   (South Korea)

Author keywords

IL 6; IL 8; Lysophosphatidic acid; Oral squamous cell carcinoma; Osteoclastogenesis; RANKL

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 8; LAMIN C; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PARATHYROID HORMONE RELATED PROTEIN RECEPTOR; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE B; PROTEIN P50; RECOMBINANT INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 8; STAT3 PROTEIN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE METASTASIS; CANCER GROWTH; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; MOUTH CARCINOMA; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SQUAMOUS CELL CARCINOMA;

ANIMALS; BIOLOGICAL ASSAY; BLOTTING, WESTERN; BONE NEOPLASMS; BONE RESORPTION; CARCINOMA, SQUAMOUS CELL; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LYSOPHOSPHOLIPIDS; MICE; MOUTH NEOPLASMS; OSTEOCLASTS; RANK LIGAND; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84855884172     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.08.022     Document Type: Article

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