Ring structure and aromatic substituent effects on the p K a of the benzoxaborole pharmacophore

ACS Medicinal Chemistry Letters

Volumn 3, Issue 1, 2012, Pages 48-52

  Tomsho, John W ^a   Pal, Arnab ^b   Hall, Dennis G ^b   Benkovic, Stephen J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

benzoboroxole; benzoxaborin; Benzoxaborole; boronic acid; diol binding; Hammett relationship; oxaborole; pK a prediction

Indexed keywords

3,3 DIMETHYL BENZOXABORALE; AROMATIC COMPOUND; BENZOXABORIN; BENZOXABOROLE; BORONIC ACID DERIVATIVE; CHEMICAL COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; EXAMINATION; IONIZATION; PHARMACOPHORE; PHYSIOLOGY; PKA; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

EID: 84855876297     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200215j     Document Type: Article

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