-
1
-
-
0038387389
-
Hit and lead generation: Beyond high-throughput screening
-
DOI 10.1038/nrd1086
-
Bleicher KH, B̈ohm HJ, M̈uller K, Alanine AI. 2003. Hit and lead generation: beyond high-throughput screening. Nat. Rev. Drug Discov. 2:369-78 (Pubitemid 37361707)
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, Issue.5
, pp. 369-378
-
-
Bleicher, K.H.1
Bohm, H.-J.2
Muller, K.3
Alanine, A.I.4
-
3
-
-
11144318686
-
New methods for automated phenotyping of complex cellular behaviors
-
Conference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004
-
Hack A, Ahouse J, Roberts P, Garakani A. 2004. New methods for automated phenotyping of complex cellular behaviors. Conf. Proc. IEEE Eng. Med. Biol. Soc. 7:5124-26 (Pubitemid 40035011)
-
(2004)
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
, vol.26
, pp. 5124-5126
-
-
Hack, A.A.1
Ahouse, J.2
Roberts, P.G.3
Garakani, A.M.4
-
4
-
-
33644858668
-
In vitro screening of drug metabolism during drug development: Can we trust the predictions?
-
Pelkonen O, Raunio H. 2005. In vitro screening of drug metabolism during drug development: can we trust the predictions? Expert Opin. Drug Metab. Toxicol. 1:49-59
-
(2005)
Expert Opin. Drug Metab. Toxicol.
, vol.1
, pp. 49-59
-
-
Pelkonen, O.1
Raunio, H.2
-
5
-
-
0142167588
-
Zebrafish-Based small molecule discovery
-
DOI 10.1016/j.chembiol.2003.10.003
-
MacRae CA, Peterson RT. 2003. Zebrafish-based small molecule discovery. Chem. Biol. 10:901-8 (Pubitemid 37316907)
-
(2003)
Chemistry and Biology
, vol.10
, Issue.10
, pp. 901-908
-
-
MacRae, C.A.1
Peterson, R.T.2
-
6
-
-
12144273121
-
In vivo drug discovery in the zebrafish
-
DOI 10.1038/nrd1606
-
Zon LI, Peterson RT. 2005. In vivo drug discovery in the zebrafish. Nat. Rev. Drug Discov. 4:35-44 (Pubitemid 40109588)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.1
, pp. 35-44
-
-
Zon, L.I.1
Peterson, R.T.2
-
7
-
-
33845769956
-
Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens
-
DOI 10.1016/j.drudis.2006.10.006, PII S1359644606004284
-
Perrimon N, Friedman A, Mathey-Prevot B, Eggert US. 2007. Drug-target identification in Drosophila cells: combining high-throughput RNAi and small-molecule screens. Drug Discov. Today 12:28-33 (Pubitemid 46014477)
-
(2007)
Drug Discovery Today
, vol.12
, Issue.1-2
, pp. 28-33
-
-
Perrimon, N.1
Friedman, A.2
Mathey-Prevot, B.3
Eggert, U.S.4
-
8
-
-
77953708536
-
Cardiac arrhythmia: In vivo screening in the zebrafish to overcome complexity in drug discovery
-
MacRae CA. 2010. Cardiac arrhythmia: In vivo screening in the zebrafish to overcome complexity in drug discovery. Expert Opin. Drug Discov. 5:619-32
-
(2010)
Expert Opin. Drug Discov.
, vol.5
, pp. 619-632
-
-
MacRae, C.A.1
-
9
-
-
0346728473
-
Systematic genome-wide screens of gene function
-
DOI 10.1038/nrg1248
-
Carpenter AE, Sabatini DM. 2004. Systematic genome-wide screens of gene function. Nat. Rev. Genet. 5:11-22 (Pubitemid 38055332)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.1
, pp. 11-22
-
-
Carpenter, A.E.1
Sabatini, D.M.2
-
10
-
-
0036244951
-
The art and design of genetic screens: Drosophila melanogaster
-
DOI 10.1038/nrg751
-
St Johnston D. 2002. The art and design of genetic screens: Drosophila melanogaster. Nat. Rev. Genet. 3:176-88 (Pubitemid 34506586)
-
(2002)
Nature Reviews Genetics
, vol.3
, Issue.3
, pp. 176-188
-
-
St Johnston, D.1
-
11
-
-
0035657098
-
The art and design of genetic screens: Zebrafish
-
DOI 10.1038/35103567
-
Patton EE, Zon LI. 2001. The art and design of genetic screens: zebrafish. Nat. Rev. Genet. 2:956-66 (Pubitemid 33691092)
-
(2001)
Nature Reviews Genetics
, vol.2
, Issue.12
, pp. 956-966
-
-
Patton, E.E.1
Zon, L.I.2
-
12
-
-
0038010068
-
Chemical genetics: Adding to the developmental biology toolbox
-
DOI 10.1016/S1534-5807(03)00200-4, PII S1534580703002004
-
Yeh JR, Crews CM. 2003. Chemical genetics: adding to the developmental biology toolbox. Dev. Cell 5:11-19 (Pubitemid 36827338)
-
(2003)
Developmental Cell
, vol.5
, Issue.1
, pp. 11-19
-
-
Yeh, J.-R.J.1
Crews, C.M.2
-
13
-
-
0034331004
-
Chemical genetics: Ligand-based discovery of gene function
-
Stockwell BR. 2000. Chemical genetics: ligand-based discovery of gene function. Nat. Rev. Genet. 1:116-25
-
(2000)
Nat. Rev. Genet.
, vol.1
, pp. 116-125
-
-
Stockwell, B.R.1
-
14
-
-
77249135113
-
Rapid behavior-based identification of neuroactive small molecules in the zebrafish
-
Kokel D, Bryan J, Laggner C, White R, Cheung CY, et al. 2010. Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nat. Chem. Biol. 6:231-37
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 231-237
-
-
Kokel, D.1
Bryan, J.2
Laggner, C.3
White, R.4
Cheung, C.Y.5
-
15
-
-
33749208029
-
Morphants: A new systematic vertebrate functional genomics approach
-
DOI 10.1002/1097-0061(200012)17:4<302::AID-YEA53>3.0.CO;2-#
-
Ekker SC. 2000. Morphants: a new systematic vertebrate functional genomics approach. Yeast 17:302-6 (Pubitemid 32051423)
-
(2000)
Comparative and Functional Genomics
, vol.17
, Issue.4
, pp. 302-306
-
-
Ekker, S.C.1
-
16
-
-
0031884192
-
Zebrafish: Genomics on the fast track
-
Beier DR. 1998. Zebrafish: genomics on the fast track. Genome Res. 8:9-17 (Pubitemid 28066110)
-
(1998)
Genome Research
, vol.8
, Issue.1
, pp. 9-17
-
-
Beier, D.R.1
-
17
-
-
0034947209
-
The zebrafish as a novel system for functional genomics and therapeutic development applications
-
Nasevicius A, Ekker SC. 2001. The zebrafish as a novel system for functional genomics and therapeutic development applications. Curr. Opin. Mol. Ther. 3:224-28 (Pubitemid 32624569)
-
(2001)
Current Opinion in Molecular Therapeutics
, vol.3
, Issue.3
, pp. 224-228
-
-
Nasevicius, A.1
Ekker, S.C.2
-
19
-
-
33846338473
-
Modeling human muscle disease in zebrafish
-
DOI 10.1016/j.bbadis.2006.07.003, PII S092544390600127X
-
Guyon JR, Steffen LS, Howell MH, Pusack TJ, LawrenceC,Kunkel LM. 2007. Modeling human muscle disease in zebrafish. Biochim. Biophys. Acta 1772:205-15 (Pubitemid 46127824)
-
(2007)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1772
, Issue.2
, pp. 205-215
-
-
Guyon, J.R.1
Steffen, L.S.2
Howell, M.H.3
Pusack, T.J.4
Lawrence, C.5
Kunkel, L.M.6
-
20
-
-
34247186766
-
Animal models of human disease: Zebrafish swim into view
-
DOI 10.1038/nrg2091, PII NRG2091
-
Lieschke GJ, Currie PD. 2007. Animal models of human disease: zebrafish swim into view. Nat. Rev. Genet. 8:353-67 (Pubitemid 46625809)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.5
, pp. 353-367
-
-
Lieschke, G.J.1
Currie, P.D.2
-
21
-
-
0038636259
-
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish
-
DOI 10.1210/me.2002-0392
-
Liu NA, Huang H, Yang Z, Herzog W,Hammerschmidt M, et al. 2003. Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Mol. Endocrinol. 17:959-66 (Pubitemid 36539584)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.5
, pp. 959-966
-
-
Liu, N.-A.1
Huang, H.2
Yang, Z.3
Herzog, W.4
Hammerschmidt, M.5
Lin, S.6
Melmed, S.7
-
24
-
-
0036527963
-
Zebrafish as a cancer model system
-
DOI 10.1016/S1535-6108(02)00052-1
-
Amatruda JF, Shepard JL, Stern HM, Zon LI. 2002. Zebrafish as a cancer model system. Cancer Cell 1:229-31 (Pubitemid 41039146)
-
(2002)
Cancer Cell
, vol.1
, Issue.3
, pp. 229-231
-
-
Amatruda, J.F.1
Shepard, J.L.2
Stern, H.M.3
Zon, L.I.4
-
25
-
-
0041817808
-
Zebrafish: A new model on the pharmaceutical catwalk
-
DOI 10.1002/bies.10326
-
Langheinrich U. 2003. Zebrafish: a new model on the pharmaceutical catwalk. BioEssays 25:904-12 (Pubitemid 37081756)
-
(2003)
BioEssays
, vol.25
, Issue.9
, pp. 904-912
-
-
Langheinrich, U.1
-
26
-
-
0037453021
-
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish
-
DOI 10.1161/01.CIR.0000061912.88753.87
-
Milan DJ, Peterson TA, Ruskin JN, Peterson RT, MacRae CA. 2003. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation 107:1355-58 (Pubitemid 36350731)
-
(2003)
Circulation
, vol.107
, Issue.10
, pp. 1355-1358
-
-
Milan, D.J.1
Peterson, T.A.2
Ruskin, J.N.3
Peterson, R.T.4
MacRae, C.A.5
-
27
-
-
0041326750
-
Development of the heart: (3) Formation of the ventricular outflow tracts, arterial valves, and intrapericardial arterial trunks
-
Anderson RH, Webb S, Brown NA, Lamers W, Moorman A. 2003. Development of the heart: (3) Formation of the ventricular outflow tracts, arterial valves, and intrapericardial arterial trunks. Heart 89:1110-18 (Pubitemid 37046862)
-
(2003)
Heart
, vol.89
, Issue.9
, pp. 1110-1118
-
-
Anderson, R.H.1
Webb, S.2
Brown, N.A.3
Lamers, W.4
Moorman, A.5
-
29
-
-
0036389722
-
Construction of a zebrafish cDNA microarray: Gene expression profiling of the zebrafish during development
-
Ton C, Stamatiou D, Dzau VJ, Liew CC. 2002. Construction of a zebrafish cDNA microarray: gene expression profiling of the zebrafish during development. Biochem. Biophys. Res. Commun. 296:1134-42
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 1134-1142
-
-
Ton, C.1
Stamatiou, D.2
Dzau, V.J.3
Liew, C.C.4
-
30
-
-
33746238115
-
Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish
-
DOI 10.1124/mol.106.025304
-
Carney SA, Chen J, Burns CG, Xiong KM, Peterson RE, Heideman W. 2006. Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish. Mol. Pharmacol. 70:549-61 (Pubitemid 44092316)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.2
, pp. 549-561
-
-
Carney, S.A.1
Chen, J.2
Burns, C.G.3
Xiong, K.M.4
Peterson, R.E.5
Heideman, W.6
-
31
-
-
0033780376
-
Effective targeted gene "knockdown" in zebrafish
-
Nasevicius A, Ekker SC. 2000. Effective targeted gene "knockdown" in zebrafish. Nat. Genet. 26:216-20
-
(2000)
Nat. Genet.
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
32
-
-
0037025203
-
Target-selected inactivation of the zebrafish rag1 gene
-
DOI 10.1126/science.1071762
-
Wienholds E, Schulte-Merker S, Walderich B, Plasterk RH. 2002. Target-selected inactivation of the zebrafish rag1 gene. Science 297:99-102 (Pubitemid 34743101)
-
(2002)
Science
, vol.297
, Issue.5578
, pp. 99-102
-
-
Wienholds, E.1
Schulte-Merker, S.2
Walderich, B.3
Plasterk, R.H.A.4
-
33
-
-
44949162060
-
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
-
DOI 10.1038/nbt1398, PII NBT1398
-
Meng X, Noyes MB, Zhu LJ, Lawson ND, Wolfe SA. 2008. Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat. Biotechnol. 26:695-701 (Pubitemid 351809594)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.6
, pp. 695-701
-
-
Meng, X.1
Noyes, M.B.2
Zhu, L.J.3
Lawson, N.D.4
Wolfe, S.A.5
-
34
-
-
74949084393
-
Targeted mutagenesis in zebrafish using customized zinc-finger nucleases
-
Foley JE, Maeder ML, Pearlberg J, Joung JK, Peterson RT, Yeh JR. 2009. Targeted mutagenesis in zebrafish using customized zinc-finger nucleases. Nat. Protoc. 4:1855-67
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1855-1867
-
-
Foley, J.E.1
Maeder, M.L.2
Pearlberg, J.3
Joung, J.K.4
Peterson, R.T.5
Yeh, J.R.6
-
35
-
-
0036254584
-
The art and design of genetic screens: Caenorhabditis elegans
-
DOI 10.1038/nrg794
-
Jorgensen EM, Mango SE. 2002. The art and design of genetic screens: Caenorhabditis elegans. Nat. Rev. Genet. 3:356-69 (Pubitemid 34506717)
-
(2002)
Nature Reviews Genetics
, vol.3
, Issue.5
, pp. 356-369
-
-
Jorgensen, E.M.1
Mango, S.E.2
-
36
-
-
0034331003
-
Capitalizing on large-scale mouse mutagenesis screens
-
Justice MJ. 2000. Capitalizing on large-scale mouse mutagenesis screens. Nat. Rev. Genet. 1:109-15
-
(2000)
Nat. Rev. Genet.
, vol.1
, pp. 109-115
-
-
Justice, M.J.1
-
37
-
-
0141732260
-
Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening
-
DOI 10.1021/ja035334d
-
Khersonsky SM, Jung DW, Kang TW, Walsh DP, Moon HS, et al. 2003. Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening. J. Am. Chem. Soc. 125:11804-5 (Pubitemid 37175399)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.39
, pp. 11804-11805
-
-
Khersonsky, S.M.1
Jung, D.-W.2
Kang, T.-W.3
Walsh, D.P.4
Moon, H.-S.5
Jo, H.6
Jacobson, E.M.7
Shetty, V.8
Neubert, T.A.9
Chang, Y.-T.10
-
39
-
-
0035797939
-
Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul
-
DOI 10.1016/S0960-9822(01)00482-1
-
Peterson RT, Mably JD, Chen JN, Fishman MC. 2001. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr. Biol. 11:1481-91 (Pubitemid 32931009)
-
(2001)
Current Biology
, vol.11
, Issue.19
, pp. 1481-1491
-
-
Peterson, R.T.1
Mably, J.D.2
Chen, J.-N.3
Fishman, M.C.4
-
40
-
-
2342454415
-
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation
-
DOI 10.1038/nbt963
-
Peterson RT, Shaw SY, Peterson TA, Milan DJ, Zhong TP, et al. 2004. Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat. Biotechnol. 22:595-99 (Pubitemid 38585912)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.5
, pp. 595-599
-
-
Peterson, R.T.1
Shaw, S.Y.2
Peterson, T.A.3
Milan, D.J.4
Zhong, T.P.5
Schreiber, S.L.6
MacRae, C.A.7
Fishman, M.C.8
-
41
-
-
37249010753
-
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
-
DOI 10.1038/nchembio.2007.54, PII NCHEMBIO200754
-
Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, et al. 2008. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat. Chem. Biol. 4:33-41 (Pubitemid 350273653)
-
(2008)
Nature Chemical Biology
, vol.4
, Issue.1
, pp. 33-41
-
-
Yu, P.B.1
Hong, C.C.2
Sachidanandan, C.3
Babitt, J.L.4
Deng, D.Y.5
Hoyng, S.A.6
Lin, H.Y.7
Bloch, K.D.8
Peterson, R.T.9
-
42
-
-
38949180229
-
AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression
-
DOI 10.1242/dev.008904
-
Yeh JR, Munson KM,Chao YL, Peterson QP,Macrae CA, Peterson RT. 2008. AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. Development 135:401-10 (Pubitemid 351228431)
-
(2008)
Development
, vol.135
, Issue.2
, pp. 401-410
-
-
Yeh, J.-R.J.1
Munson, K.M.2
Chao, Y.L.3
Peterson, Q.P.4
MacRae, C.A.5
Peterson, R.T.6
-
43
-
-
33645729418
-
Notch1b and neuregulin are required for specification of central cardiac conduction tissue
-
Milan DJ, Giokas AC, Serluca FC, Peterson RT,MacRae CA. 2006. Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development 133:1125-32
-
(2006)
Development
, vol.133
, pp. 1125-1132
-
-
Milan, D.J.1
Giokas, A.C.2
Serluca, F.C.3
Peterson, R.T.4
MacRae, C.A.5
-
44
-
-
22544471264
-
Animal models for arrhythmias
-
DOI 10.1016/j.cardiores.2005.06.012, PII S0008636305002889
-
Milan DJ, MacRae CA. 2005. Animal models for arrhythmias. Cardiovasc. Res. 67:426-37 (Pubitemid 41019550)
-
(2005)
Cardiovascular Research
, vol.67
, Issue.3
, pp. 426-437
-
-
Milan, D.J.1
MacRae, C.A.2
-
45
-
-
57349171954
-
BMP type i receptor inhibition reduces heterotopic [corrected] ossification
-
Yu PB, Deng DY, Lai CS, Hong CC, Cuny GD, et al. 2008. BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat. Med. 14:1363-69
-
(2008)
Nat. Med.
, vol.14
, pp. 1363-1369
-
-
Yu, P.B.1
Deng, D.Y.2
Lai, C.S.3
Hong, C.C.4
Cuny, G.D.5
-
46
-
-
51449091152
-
Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
-
Hao J, Daleo MA, Murphy CK, Yu PB, Ho JN, et al. 2008. Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS ONE 3:e2904
-
(2008)
PLoS ONE
, vol.3
-
-
Hao, J.1
Daleo, M.A.2
Murphy, C.K.3
Yu, P.B.4
Ho, J.N.5
-
47
-
-
23844494458
-
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis
-
DOI 10.1038/nature03876
-
Gunsalus KC, Ge H, Schetter AJ, Goldberg DS, Han JD, et al. 2005. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature 436:861-65 (Pubitemid 41160646)
-
(2005)
Nature
, vol.436
, Issue.7052
, pp. 861-865
-
-
Gunsalus, K.C.1
Ge, H.2
Schetter, A.J.3
Goldberg, D.S.4
Han, J.-D.J.5
Hao, T.6
Berriz, G.F.7
Bertin, N.8
Huang, J.9
Chuang, L.-S.10
Li, N.11
Mani, R.12
Hyman, A.A.13
Sonnichsen, B.14
Echeverri, C.J.15
Roth, F.P.16
Vidal, M.17
Piano, F.18
-
48
-
-
0037137446
-
Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline
-
DOI 10.1016/S0960-9822(02)01279-4, PII S0960982202012794
-
Walhout AJ, Reboul J, Shtanko O, Bertin N, Vaglio P, et al. 2002. Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Curr. Biol. 12:1952-58 (Pubitemid 35426710)
-
(2002)
Current Biology
, vol.12
, Issue.22
, pp. 1952-1958
-
-
Walhout, A.J.M.1
Reboul, J.2
Shtanko, O.3
Bertin, N.4
Vaglio, P.5
Ge, H.6
Lee, H.7
Doucette-Stamm, L.8
Gunsalus, K.C.9
Schetter, A.J.10
Morton, D.G.11
Kemphues, K.J.12
Reinke, V.13
Kim, S.K.14
Piano, F.15
Vidal, M.16
-
49
-
-
70849128432
-
Applications of small molecule BMP inhibitors in physiology and disease
-
Hong CC, Yu PB. 2009. Applications of small molecule BMP inhibitors in physiology and disease. Cytokine Growth Factor Rev. 20:409-18
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 409-418
-
-
Hong, C.C.1
Yu, P.B.2
-
50
-
-
0035544476
-
Green fluorescent protein (GFP) transgenic fish and their applications
-
DOI 10.1023/A:1013796810782
-
Gong Z, Ju B, Wan H. 2001. Green fluorescent protein (GFP) transgenic fish and their applications. Genetica 111:213-25 (Pubitemid 34115225)
-
(2001)
Genetica
, vol.111
, Issue.1-3
, pp. 213-225
-
-
Gong, Z.1
Ju, B.2
Wan, H.3
-
51
-
-
67649393372
-
Imaging zebrafish embryos by two-photon excitation time-lapse microscopy
-
Carvalho L, Heisenberg CP. 2009. Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. Methods Mol. Biol. 546:273-87
-
(2009)
Methods Mol. Biol.
, vol.546
, pp. 273-287
-
-
Carvalho, L.1
Heisenberg, C.P.2
-
52
-
-
33645972938
-
Purification of hearts from zebrafish embryos
-
Burns CG, MacRae CA. 2006. Purification of hearts from zebrafish embryos. Biotechniques 40:278-82
-
(2006)
Biotechniques
, vol.40
, pp. 278-282
-
-
Burns, C.G.1
MacRae, C.A.2
-
53
-
-
0035907008
-
Genetic analysis of digestive physiology using fluorescent phospholipid reporters
-
DOI 10.1126/science.1060418
-
Farber SA, Pack M, Ho SY, Johnson ID, Wagner DS, et al. 2001. Genetic analysis of digestive physiology using fluorescent phospholipid reporters. Science 292:1385-88 (Pubitemid 32476227)
-
(2001)
Science
, vol.292
, Issue.5520
, pp. 1385-1388
-
-
Farber, S.A.1
Pack, M.2
Ho, S.-Y.3
Johnson, I.D.4
Wagner, D.S.5
Dosch, R.6
Mullins, M.C.7
Hendrickson, H.S.8
Hendrickson, E.K.9
Halpern, M.E.10
-
54
-
-
79951983956
-
FLIM FRET technology for drug discovery: Automated multiwell-plate high-content analysis, multiplexed readouts and application in situ
-
Kumar S, Alibhai D, Margineanu A, Laine R, Kennedy G, et al. 2011. FLIM FRET technology for drug discovery: automated multiwell-plate high-content analysis, multiplexed readouts and application in situ. ChemPhysChem 12:609-26
-
(2011)
ChemPhysChem
, vol.12
, pp. 609-626
-
-
Kumar, S.1
Alibhai, D.2
Margineanu, A.3
Laine, R.4
Kennedy, G.5
-
55
-
-
55949096258
-
2+ exchanger monitored by FRET in transgenic zebrafish heart
-
DOI 10.1152/ajpcell.00178.2008
-
Xie Y, Ottolia M, John SA, Chen JN, Philipson KD. 2008. Conformational changes of a Ca2+binding domain of the Na? exchanger monitored by FRET in transgenic zebrafish heart. Am. J. Physiol. Cell Physiol. 295:C388-93 (Pubitemid 352755764)
-
(2008)
American Journal of Physiology - Cell Physiology
, vol.295
, Issue.2
-
-
Xie, Y.1
Ottolia, M.2
John, S.A.3
Chen, J.-N.4
Philipson, K.D.5
-
56
-
-
66149128896
-
Transcriptome transfer produces a predictable cellular phenotype
-
Sul JY,WuCW, Zeng F, Jochems J, LeeMT, et al. 2009. Transcriptome transfer produces a predictable cellular phenotype. Proc. Natl. Acad. Sci. USA 106:7624-29
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 7624-7629
-
-
Sul, J.Y.1
Wu, C.W.2
Zeng, F.3
Jochems, J.4
Lee, M.T.5
-
57
-
-
67649158624
-
A novel application ofmetabolomics in vertebrate development
-
Hayashi S, Akiyama S, Tamaru Y, Takeda Y, Fujiwara T, et al. 2009. A novel application ofmetabolomics in vertebrate development. Biochem. Biophys. Res. Commun. 386:268-72
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.386
, pp. 268-272
-
-
Hayashi, S.1
Akiyama, S.2
Tamaru, Y.3
Takeda, Y.4
Fujiwara, T.5
-
58
-
-
60649084394
-
A multi-analytical approach for metabolomic profiling of zebrafish (Danio rerio) livers
-
Ong ES, Chor CF, Zou L, Ong CN. 2009. A multi-analytical approach for metabolomic profiling of zebrafish (Danio rerio) livers. Mol. Biosyst. 5:288-98
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 288-298
-
-
Ong, E.S.1
Chor, C.F.2
Zou, L.3
Ong, C.N.4
-
59
-
-
16644370612
-
Genetic backgrounds, standard lines, and husbandry of zebrafish
-
Trevarrow B,Robison B. 2004. Genetic backgrounds, standard lines, and husbandry of zebrafish. Methods Cell Biol. 77:599-616
-
(2004)
Methods Cell Biol.
, vol.77
, pp. 599-616
-
-
Trevarrow, B.1
Robison, B.2
-
60
-
-
37049028158
-
Automated, quantitative screening assay for antiangiogenic compounds using transgenic zebrafish
-
DOI 10.1158/0008-5472.CAN-07-3126
-
Tran TC, Sneed B, Haider J, Blavo D,White A, et al. 2007. Automated, quantitative screening assay for antiangiogenic compounds using transgenic zebrafish. Cancer Res. 67:11386-92 (Pubitemid 350248566)
-
(2007)
Cancer Research
, vol.67
, Issue.23
, pp. 11386-11392
-
-
Tran, T.C.1
Sneed, B.2
Haider, J.3
Blavo, D.4
White, A.5
Aiyejorun, T.6
Baranowski, T.C.7
Rubinstein, A.L.8
Doan, T.N.9
Dingledine, R.10
Sandberg, E.M.11
-
61
-
-
33644824638
-
High-throughput assay for small molecules that modulate zebrafish embryonic heart rate
-
Burns CG, Milan DJ, Grande EJ, Rottbauer W, MacRae CA, Fishman MC. 2005. High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nat. Chem. Biol. 1:263-64
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 263-264
-
-
Burns, C.G.1
Milan, D.J.2
Grande, E.J.3
Rottbauer, W.4
MacRae, C.A.5
Fishman, M.C.6
-
62
-
-
69549124105
-
Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization
-
Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, et al. 2009. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation 120:553-59
-
(2009)
Circulation
, vol.120
, pp. 553-559
-
-
Milan, D.J.1
Kim, A.M.2
Winterfield, J.R.3
Jones, I.L.4
Pfeufer, A.5
-
63
-
-
70949107133
-
Chondroitin sulfate expression is required for cardiac atrioventricular canal formation
-
Peal DS, Burns CG, Macrae CA, Milan D. 2009. Chondroitin sulfate expression is required for cardiac atrioventricular canal formation. Dev. Dyn. 238:3103-10
-
(2009)
Dev. Dyn.
, vol.238
, pp. 3103-3110
-
-
Peal, D.S.1
Burns, C.G.2
MacRae, C.A.3
Milan, D.4
-
64
-
-
32344448950
-
Statistical practice in high-throughput screening data analysis
-
DOI 10.1038/nbt1186, PII NBT1186
-
Malo N, Hanley JA, Cerquozzi S, Pelletier J, Nadon R. 2006. Statistical practice in high-throughput screening data analysis. Nat. Biotechnol. 24:167-75 (Pubitemid 43221699)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.2
, pp. 167-175
-
-
Malo, N.1
Hanley, J.A.2
Cerquozzi, S.3
Pelletier, J.4
Nadon, R.5
-
65
-
-
43749109828
-
Development of enteric and vagal innervation of the zebrafish (Danio rerio) gut
-
DOI 10.1002/cne.21705
-
OlssonC,HolmbergA,Holmgren S. 2008. Development of enteric and vagal innervation of the zebrafish (Danio rerio) gut. J. Comp. Neurol. 508:756-70 (Pubitemid 351693559)
-
(2008)
Journal of Comparative Neurology
, vol.508
, Issue.5
, pp. 756-770
-
-
Olsson, C.1
Holmberg, A.2
Holmgren, S.3
-
66
-
-
0036478894
-
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin
-
Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, et al. 2002. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nat. Genet. 30:205-9
-
(2002)
Nat. Genet.
, vol.30
, pp. 205-9
-
-
Xu, X.1
Meiler, S.E.2
Zhong, T.P.3
Mohideen, M.4
Crossley, D.A.5
-
67
-
-
0036478897
-
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
-
Gerull B, Gramlich M, Atherton J, McNabb M, Trombitas K, et al. 2002. Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy. Nat. Genet. 30:201-4
-
(2002)
Nat. Genet.
, vol.30
, pp. 201-4
-
-
Gerull, B.1
Gramlich, M.2
Atherton, J.3
McNabb, M.4
Trombitas, K.5
-
68
-
-
0028803128
-
Gridlock, a localized heritable vascular patterning defect in the zebrafish
-
Weinstein BM, Stemple DL, Driever W, Fishman MC. 1995. gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat. Med. 1:1143-47
-
(1995)
Nat. Med.
, vol.1
, pp. 1143-1147
-
-
Weinstein, B.M.1
Stemple, D.L.2
Driever, W.3
Fishman, M.C.4
-
69
-
-
77951160785
-
ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish
-
Ren B, Deng Y, Mukhopadhyay A, Lanahan AA, Zhuang ZW, et al. 2010. ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish. J. Clin. Investig. 120:1217-28
-
(2010)
J. Clin. Investig.
, vol.120
, pp. 1217-1228
-
-
Ren, B.1
Deng, Y.2
Mukhopadhyay, A.3
Lanahan, A.A.4
Zhuang, Z.W.5
-
71
-
-
84861409753
-
Rapidmutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN)
-
Foley JE, Yeh JR, Maeder ML,Reyon D, Sander JD, et al. 2009. Rapidmutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN). PLoS ONE 4:e4348
-
(2009)
PLoS ONE
, vol.4
-
-
Foley, J.E.1
Yeh, J.R.2
Maeder, M.L.3
Reyon, D.4
Sander, J.D.5
-
72
-
-
78751604246
-
Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen
-
Peal DS,Mills RW, Lynch SN,Mosley JM, Lim E, et al. 2011. Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen. Circulation 123:23-30
-
(2011)
Circulation
, vol.123
, pp. 23-30
-
-
Peal, D.S.1
Mills, R.W.2
Lynch, S.N.3
Mosley, J.M.4
Lim, E.5
-
73
-
-
11144297183
-
Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers
-
DOI 10.1016/j.ijrobp.2004.09.046, PII S036030160402680X
-
McAleer MF, Davidson C, DavidsonWR, Yentzer B, Farber SA, et al. 2005. Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers. Int. J. Radiat. Oncol. Biol. Phys. 61:10-13 (Pubitemid 40039099)
-
(2005)
International Journal of Radiation Oncology Biology Physics
, vol.61
, Issue.1
, pp. 10-13
-
-
McAleer, M.F.1
Davidson, C.2
Davidson, W.R.3
Yentzer, B.4
Farber, S.A.5
Rodeck, U.6
Dicker, A.P.7
-
74
-
-
70349439013
-
-
Lammer E, Kamp HG, Hisgen V, Koch M, Reinhard D, et al. 2009. Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Toxicol. In Vitro 23:1436-42
-
(2009)
Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Toxicol
, vol.23
, pp. 1436-1442
-
-
Lammer, E.1
Kamp, H.G.2
Hisgen, V.3
Koch, M.4
Reinhard, D.5
-
75
-
-
77953521553
-
In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays
-
Augustine-Rauch K, Zhang CX, Panzica-Kelly JM. 2010. In vitro developmental toxicology assays: a review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays. Birth Defects Res. C 90:87-98
-
(2010)
Birth Defects Res. C
, vol.90
, pp. 87-98
-
-
Augustine-Rauch, K.1
Zhang, C.X.2
Panzica-Kelly, J.M.3
-
77
-
-
79952201413
-
Evaluation of embryotoxicity using the zebrafish model
-
Truong L, Harper SL, Tanguay RL. 2011. Evaluation of embryotoxicity using the zebrafish model. Methods Mol. Biol. 691:271-79
-
(2011)
Methods Mol. Biol.
, vol.691
, pp. 271-279
-
-
Truong, L.1
Harper, S.L.2
Tanguay, R.L.3
-
78
-
-
0032552038
-
Mechanisms and management of proarrhythmia
-
Roden DM. 1998. Mechanisms and management of proarrhythmia. Am. J. Cardiol. 82:491-57
-
(1998)
Am. J. Cardiol.
, vol.82
, pp. 491-457
-
-
Roden, D.M.1
-
79
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
DOI 10.1016/S0092-8674(01)00243-4
-
Keating MT, Sanguinetti MC. 2001. Molecular and cellular mechanisms of cardiac arrhythmias. Cell 104:569-80 (Pubitemid 32201951)
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
80
-
-
0033916119
-
Congenital and acquired long QT syndrome
-
DOI 10.1053/euhj.2000.2222
-
Camm AJ, Janse MJ, Roden DM, Rosen MR, Cinca J, Cobbe SM. 2000. Congenital and acquired long QT syndrome. Eur. Heart J. 21:1232-37 (Pubitemid 30487770)
-
(2000)
European Heart Journal
, vol.21
, Issue.15
, pp. 1232-1237
-
-
Camm, A.J.1
Janse, M.J.2
Roden, D.M.3
Rosen, M.R.4
Cinca, J.5
Cobbe, S.M.6
-
81
-
-
0029002969
-
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
-
Sanguinetti MC, Jiang C, CurranME, KeatingMT. 1995. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81:299-307
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
Keating, M.T.4
-
82
-
-
0029761822
-
HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine
-
Roy M, Dumaine R, Brown AM. 1996. HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. Circulation 94:817-23 (Pubitemid 26289240)
-
(1996)
Circulation
, vol.94
, Issue.4
, pp. 817-823
-
-
Roy, M.-L.1
Dumaine, R.2
Brown, A.M.3
-
83
-
-
0034231822
-
Drugs that prolong QT interval as an unwanted effect: Assessing their likelihood of inducing hazardous cardiac dysrhythmias
-
Cavero I, Mestre M, Guillon JM, Crumb W. 2000. Drugs that prolong QT interval as an unwanted effect: assessing their likelihood of inducing hazardous cardiac dysrhythmias. Expert Opin. Pharmacother. 1:947-73
-
(2000)
Expert Opin. Pharmacother.
, vol.1
, pp. 947-973
-
-
Cavero, I.1
Mestre, M.2
Guillon, J.M.3
Crumb, W.4
-
84
-
-
0034710933
-
A structural basis for drug-induced long QT syndrome
-
Mitcheson JS, Chen J, Lin M, Culberson C, Sanguinetti MC. 2000. A structural basis for drug-induced long QT syndrome. Proc. Natl. Acad. Sci. USA 97:12329-33
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12329-12333
-
-
Mitcheson, J.S.1
Chen, J.2
Lin, M.3
Culberson, C.4
Sanguinetti, M.C.5
-
85
-
-
0034774943
-
Kr: Model systems and relevance to human arrhythmias
-
DOI 10.1097/00005344-200111000-00010
-
Yang T, Snyders D, Roden DM. 2001. Drug block of Ikr: model systems and relevance to human arrhythmias. J. Cardiovasc. Pharmacol. 38:737-44 (Pubitemid 32983280)
-
(2001)
Journal of Cardiovascular Pharmacology
, vol.38
, Issue.5
, pp. 737-744
-
-
Yang, T.1
Snyders, D.2
Roden, D.M.3
-
86
-
-
0035040834
-
Pharmacogenetics and drug-induced arrhythmias
-
DOI 10.1016/S0008-6363(00)00302-3, PII S0008636300003023
-
Roden DM. 2001. Pharmacogenetics and drug-induced arrhythmias. Cardiovasc. Res. 50:224-31 (Pubitemid 32382149)
-
(2001)
Cardiovascular Research
, vol.50
, Issue.2
, pp. 224-231
-
-
Roden, D.M.1
-
87
-
-
0033574273
-
MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
-
Abbott GW, Sesti F, Splawski I, Buck ME, Lehmann MH, et al. 1999. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell 97:175-87
-
(1999)
Cell
, vol.97
, pp. 175-187
-
-
Abbott, G.W.1
Sesti, F.2
Splawski, I.3
Buck, M.E.4
Lehmann, M.H.5
-
88
-
-
0032903775
-
Novel mechanism associated with an inherited cardiac arrhythmia: Defective protein trafficking by the mutant HERG (G601S) potassium channel
-
Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, et al. 1999. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel. Circulation 99:2290-94 (Pubitemid 29201136)
-
(1999)
Circulation
, vol.99
, Issue.17
, pp. 2290-2294
-
-
Furutani, M.1
Trudeau, M.C.2
Hagiwara, N.3
Seki, A.4
Gong, Q.5
Zhou, Z.6
Imamura, S.-I.7
Nagashima, H.8
Kasanuki, H.9
Takao, A.10
Momma, K.11
January, C.T.12
Robertson, G.A.13
Matsuoka, R.14
-
89
-
-
1442301518
-
The Utility of hERG and Repolarization Assays in Evaluating Delayed Cardiac Repolarization: Influence of Multi-Channel Block
-
DOI 10.1097/00005344-200403000-00007
-
Martin RL, McDermott JS, Salmen HJ, Palmatier J, Cox BF, Gintant GA. 2004. The utility of hERG and repolarization assays in evaluating delayed cardiac repolarization: influence of multi-channel block. J. Cardiovasc. Pharmacol. 43:369-79 (Pubitemid 38270603)
-
(2004)
Journal of Cardiovascular Pharmacology
, vol.43
, Issue.3
, pp. 369-379
-
-
Martin, R.L.1
McDermott, J.S.2
Salmen, H.J.3
Palmatier, J.4
Cox, B.F.5
Gintant, G.A.6
-
91
-
-
0032126163
-
Experimental models of torsade de pointes
-
DOI 10.1016/S0008-6363(98)00043-1, PII S0008636398000431
-
Eckardt L,Haverkamp W, BorggrefeM, BreithardtG. 1998. Experimental models of torsade de pointes. Cardiovasc. Res. 39:178-93 (Pubitemid 28322389)
-
(1998)
Cardiovascular Research
, vol.39
, Issue.1
, pp. 178-193
-
-
Eckardt, L.1
Haverkamp, W.2
Borggrefe, M.3
Breithardt, G.4
-
93
-
-
33750871081
-
"physiological genomics": Mutant screens in zebrafish
-
Warren KS, Fishman MC. 1998. "Physiological genomics": mutant screens in zebrafish. Am. J. Physiol. 275:H1-H7
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Warren, K.S.1
Fishman, M.C.2
-
95
-
-
12644311273
-
Mutations affecting the cardiovascular system and other internal organs in zebrafish
-
Chen JN, Haffter P, Odenthal J, Vogelsang E, Brand M, et al. 1996. Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123:293-302 (Pubitemid 27056756)
-
(1996)
Development
, vol.123
, pp. 293-302
-
-
Chen, J.-N.1
Haffter, P.2
Odenthal, J.3
Vogelsang, E.4
Brand, M.5
Van Eeden, F.J.M.6
Furutani-Seiki, M.7
Granato, M.8
Hammerschmidt, M.9
Heisenberg, C.-P.10
Jiang, Y.-J.11
Kane, D.A.12
Kelsh, R.N.13
Mullins, M.C.14
Nusslein-Volhard, C.15
-
96
-
-
0346848889
-
Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia
-
DOI 10.1016/j.taap.2003.07.012
-
Langheinrich U, VacunG,WagnerT. 2003. Zebrafish embryos express an orthologue ofHERGand are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia. Toxicol. Appl. Pharmacol. 193:370-82 (Pubitemid 37543544)
-
(2003)
Toxicology and Applied Pharmacology
, vol.193
, Issue.3
, pp. 370-382
-
-
Langheinrich, U.1
Vacun, G.2
Wagner, T.3
-
97
-
-
21344463329
-
Refining detection of drug-induced proarrhythmia: QT interval and TRIaD
-
DOI 10.1016/j.hrthm.2005.03.023, PII S1547527105014451
-
Shah RR, Hondeghem LM. 2005. Refining detection of drug-induced proarrhythmia: QT interval and TRIaD. Heart Rhythm 2:758-72 (Pubitemid 40903686)
-
(2005)
Heart Rhythm
, vol.2
, Issue.7
, pp. 758-772
-
-
Shah, R.R.1
Hondeghem, L.M.2
-
98
-
-
25444529765
-
Molecular physiology of cardiac repolarization
-
DOI 10.1152/physrev.00002.2005
-
Nerbonne JM, Kass RS. 2005. Molecular physiology of cardiac repolarization. Physiol. Rev. 85:1205-53 (Pubitemid 41362269)
-
(2005)
Physiological Reviews
, vol.85
, Issue.4
, pp. 1205-1253
-
-
Nerbonne, J.M.1
Kass, R.S.2
-
99
-
-
33745237158
-
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization
-
DOI 10.1038/ng1790, PII N1790
-
Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, et al. 2006. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat. Genet. 38:644-51 (Pubitemid 43927305)
-
(2006)
Nature Genetics
, vol.38
, Issue.6
, pp. 644-651
-
-
Arking, D.E.1
Pfeufer, A.2
Post, W.3
Kao, W.H.L.4
Newton-Cheh, C.5
Ikeda, M.6
West, K.7
Kashuk, C.8
Akyol, M.9
Perz, S.10
Jalilzadeh, S.11
Illig, T.12
Gieger, C.13
Guo, C.-Y.14
Larson, M.G.15
Wichmann, H.E.16
Marban, E.17
O'Donnell, C.J.18
Hirschhorn, J.N.19
Kaab, S.20
Spooner, P.M.21
Meitinger, T.22
Chakravarti, A.23
more..
-
100
-
-
77953711916
-
High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish
-
Shin JT, Pomerantsev EV, Mably JD, MacRae CA. 2010. High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish. Physiol. Genomics 42:300-9
-
(2010)
Physiol. Genomics
, vol.42
, pp. 300-9
-
-
Shin, J.T.1
Pomerantsev, E.V.2
Mably, J.D.3
MacRae, C.A.4
-
101
-
-
77950384564
-
Mercury-induced hepatotoxicity in zebrafish: In vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation
-
Ung CY, Lam SH, Hlaing MM, Winata CL, Korzh S, et al. 2010. Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation. BMC Genomics 11:212
-
(2010)
BMC Genomics
, vol.11
, pp. 212
-
-
Ung, C.Y.1
Lam, S.H.2
Hlaing, M.M.3
Winata, C.L.4
Korzh, S.5
-
102
-
-
17644368516
-
Acute renal failure in zebrafish: A novel system to study a complex disease
-
DOI 10.1152/ajprenal.00386.2004
-
Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. 2005. Acute renal failure in zebrafish: a novel system to study a complex disease. Am. J. Physiol. Ren. Physiol. 288:F923-29 (Pubitemid 40569758)
-
(2005)
American Journal of Physiology - Renal Physiology
, vol.288
, Issue.5
-
-
Hentschel, D.M.1
Kwon, M.P.2
Cilenti, L.3
Zervos, A.S.4
Drummond, I.5
Bonventre, J.V.6
-
103
-
-
40549095721
-
Non-associative learning in larval zebrafish
-
DOI 10.1038/sj.npp.1301489, PII 1301489
-
Best JD, Berghmans S, Hunt JJ, Clarke SC, Fleming A, et al. 2008. Non-associative learning in larval zebrafish. Neuropsychopharmacology 33:1206-15 (Pubitemid 351367546)
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.5
, pp. 1206-1215
-
-
Best, J.D.1
Berghmans, S.2
Hunt, J.J.F.G.3
Clarke, S.C.4
Fleming, A.5
Goldsmith, P.6
Roach, A.G.7
-
104
-
-
0028883523
-
A behavioral screen for isolating zebrafish mutants with visual system defects
-
Brockerhoff SE, Hurley JB, Janssen-Bienhold U, Neuhauss SC, Driever W, Dowling JE. 1995. A behavioral screen for isolating zebrafish mutants with visual system defects. Proc. Natl. Acad. Sci. USA 92:10545-49
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10545-10549
-
-
Brockerhoff, S.E.1
Hurley, J.B.2
Janssen-Bienhold, U.3
Neuhauss, S.C.4
Driever, W.5
Dowling, J.E.6
-
106
-
-
74549126594
-
Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation
-
Rihel J, Prober DA, Arvanites A, Lam K, Zimmerman S, et al. 2010. Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science 327:348-51
-
(2010)
Science
, vol.327
, pp. 348-351
-
-
Rihel, J.1
Prober, D.A.2
Arvanites, A.3
Lam, K.4
Zimmerman, S.5
-
107
-
-
36849045916
-
The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity
-
DOI 10.1172/JCI32741.
-
Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, et al. 2007. The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J. Clin. Investig. 117:3940-51 (Pubitemid 350224103)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3940-3951
-
-
Hanai, J.-I.1
Cao, P.2
Tanksale, P.3
Imamura, S.4
Koshimizu, E.5
Zhao, J.6
Kishi, S.7
Yamashita, M.8
Phillips, P.S.9
Sukhatme, V.P.10
Lecker, S.H.11
-
108
-
-
50049103885
-
Zebrafish-based assays for the assessment of cardiac, visual and gut function-potential safety screens for early drug discovery
-
Berghmans S, Butler P, Goldsmith P, Waldron G, Gardner I, et al. 2008. Zebrafish-based assays for the assessment of cardiac, visual and gut function-potential safety screens for early drug discovery. J. Pharmacol. Toxicol. Methods 58:59-68
-
(2008)
J. Pharmacol. Toxicol. Methods
, vol.58
, pp. 59-68
-
-
Berghmans, S.1
Butler, P.2
Goldsmith, P.3
Waldron, G.4
Gardner, I.5
-
109
-
-
60649102106
-
Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish
-
Field HA, Kelley KA, Martell L, Goldstein AM, Serluca FC. 2009. Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish. Neurogastroenterol. Motil. 21:304-12
-
(2009)
Neurogastroenterol. Motil.
, vol.21
, pp. 304-312
-
-
Field, H.A.1
Kelley, K.A.2
Martell, L.3
Goldstein, A.M.4
Serluca, F.C.5
-
110
-
-
34248159331
-
Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver
-
DOI 10.1152/physiolgenomics.00201.2005
-
Lam SH, Winata CL, Tong Y, Korzh S, LimWS, et al. 2006. Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver. Physiol. Genomics 27:351-61 (Pubitemid 46708786)
-
(2006)
Physiological Genomics
, vol.27
, Issue.3
, pp. 351-361
-
-
Siew, H.L.1
Winata, C.L.2
Tong, Y.3
Korzh, S.4
Wen, S.L.5
Korzh, V.6
Spitsbergen, J.7
Mathavan, S.8
Miller, L.D.9
Liu, E.T.10
Gong, Z.11
-
111
-
-
40949115532
-
Arsenate and perchlorate toxicity, growth effects, and thyroid histopathology in hypothyroid zebrafish Danio rerio
-
Liu F, Gentles A, Theodorakis CW. 2008. Arsenate and perchlorate toxicity, growth effects, and thyroid histopathology in hypothyroid zebrafish Danio rerio. Chemosphere 71:1369-76
-
(2008)
Chemosphere
, vol.71
, pp. 1369-1376
-
-
Liu, F.1
Gentles, A.2
Theodorakis, C.W.3
-
112
-
-
34347211064
-
New waves of discovery: Modeling cancer in zebrafish
-
DOI 10.1200/JCO.2006.08.9821
-
Goessling W, North TE, Zon LI. 2007. New waves of discovery: modeling cancer in zebrafish. J. Clin. Oncol. 25:2473-79 (Pubitemid 46999219)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.17
, pp. 2473-2479
-
-
Goessling, W.1
North, T.E.2
Zon, L.I.3
-
113
-
-
74049133918
-
Zebrafish tumor assays: The state of transplantation
-
Taylor AM, Zon LI. 2009. Zebrafish tumor assays: the state of transplantation. Zebrafish 6:339-46
-
(2009)
Zebrafish
, vol.6
, pp. 339-346
-
-
Taylor, A.M.1
Zon, L.I.2
-
114
-
-
38849171163
-
Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos
-
DOI 10.1002/cbic.200700565
-
Koide K, Song F, de Groh ED, Garner AL, Mitchell VD, et al. 2008. Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. ChemBioChem 9:214-18 (Pubitemid 351196789)
-
(2008)
ChemBioChem
, vol.9
, Issue.2
, pp. 214-218
-
-
Koide, K.1
Song, F.2
De Groh, E.D.3
Garner, A.L.4
Mitchell, V.D.5
Davidson, L.A.6
Hukriede, N.A.7
-
115
-
-
78349237831
-
Identification and developmental expression of the full complement of Cytochrome P450 genes in zebrafish
-
Goldstone JV, McArthur AG, Kubota A, Zanette J, Parente T, et al. 2010. Identification and developmental expression of the full complement of Cytochrome P450 genes in zebrafish. BMC Genomics 11:643
-
(2010)
BMC Genomics
, vol.11
, pp. 643
-
-
Goldstone, J.V.1
McArthur, A.G.2
Kubota, A.3
Zanette, J.4
Parente, T.5
-
116
-
-
0015821183
-
Opiate agonists and antagonists discriminated by receptor binding in brain
-
Pert CB, Pasternak G, Snyder SH. 1973. Opiate agonists and antagonists discriminated by receptor binding in brain. Science 182:1359-61
-
(1973)
Science
, vol.182
, pp. 1359-1361
-
-
Pert, C.B.1
Pasternak, G.2
Snyder, S.H.3
-
117
-
-
0029932598
-
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
-
Taunton J, Hassig CA, Schreiber SL. 1996. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272:408-11 (Pubitemid 26138177)
-
(1996)
Science
, vol.272
, Issue.5260
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
118
-
-
33846876695
-
Relating protein pharmacology by ligand chemistry
-
DOI 10.1038/nbt1284, PII NBT1284
-
Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. 2007. Relating protein pharmacology by ligand chemistry. Nat. Biotechnol. 25:197-206 (Pubitemid 46227119)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.2
, pp. 197-206
-
-
Keiser, M.J.1
Roth, B.L.2
Armbruster, B.N.3
Ernsberger, P.4
Irwin, J.J.5
Shoichet, B.K.6
-
119
-
-
0028146327
-
Mapping the auxin-binding site of auxin-binding protein 1
-
Brown JC, Jones AM. 1994. Mapping the auxin-binding site of auxin-binding protein 1. J. Biol. Chem. 269:21136-40 (Pubitemid 24266486)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.33
, pp. 21136-21140
-
-
Brown, J.C.1
Jones, A.M.2
-
120
-
-
0033117634
-
The identification of myriocin-binding proteins
-
DOI 10.1016/S1074-5521(99)80038-6
-
Chen JK, Lane WS, Schreiber SL. 1999. The identification of myriocin-binding proteins. Chem. Biol. 6:221-35 (Pubitemid 29368410)
-
(1999)
Chemistry and Biology
, vol.6
, Issue.4
, pp. 221-235
-
-
Chen, J.K.1
Lane, W.S.2
Schreiber, S.L.3
-
121
-
-
0024472603
-
A receptor for the immunosupressant FK506 is a cis-trans peptidyl-prolyl isomerase
-
DOI 10.1038/341758a0
-
HardingMW, Galat A, UehlingDE, Schreiber SL. 1989. A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Nature 341:758-60 (Pubitemid 19260893)
-
(1989)
Nature
, vol.341
, Issue.6244
, pp. 758-760
-
-
Harding, M.W.1
Galat, A.2
Uehling, D.E.3
Schreiber, S.L.4
-
122
-
-
0025021789
-
Identification and isolation of a membrane protein necessary for leukotriene production
-
Miller DK, Gillard JW, Vickers PJ, Sadowski S, Leveille C, et al. 1990. Identification and isolation of a membrane protein necessary for leukotriene production. Nature 343:278-81
-
(1990)
Nature
, vol.343
, pp. 278-281
-
-
Miller, D.K.1
Gillard, J.W.2
Vickers, P.J.3
Sadowski, S.4
Leveille, C.5
-
123
-
-
0033877274
-
High-performance affinity beads for identifying drug receptors
-
DOI 10.1038/78496
-
Shimizu N, Sugimoto K, Tang J, Nishi T, Sato I, et al. 2000. High-performance affinity beads for identifying drug receptors. Nat. Biotechnol. 18:877-81 (Pubitemid 30640915)
-
(2000)
Nature Biotechnology
, vol.18
, Issue.8
, pp. 877-881
-
-
Shimizu, N.1
Sugimoto, K.2
Tang, J.3
Nishi, T.4
Sato, I.5
Hiramoto, M.6
Aizawa, S.7
Hatakeyama, M.8
Ohba, R.9
Hatori, H.10
Yoshikawa, T.11
Suzuki, F.12
Oomori, A.13
Tanaka, H.14
Kawaguchi, H.15
Watanabe, H.16
Handa, H.17
-
124
-
-
26644443924
-
Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish
-
DOI 10.1039/b417765g
-
Jung DW,Williams D, Khersonsky SM, Kang TW, Heidary N, et al. 2005. Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish. Mol. Biosyst. 1:85-92 (Pubitemid 43349734)
-
(2005)
Molecular BioSystems
, vol.1
, Issue.1
, pp. 85-92
-
-
Jung, D.-W.1
Williams, D.2
Khersonsky, S.M.3
Kang, T.-W.4
Heidary, N.5
Chang, Y.-T.6
Orlow, S.J.7
-
125
-
-
0037009971
-
A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening
-
Moon HS, Jacobson EM, Khersonsky SM, Luzung MR, Walsh DP, et al. 2002. A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. J. Am. Chem. Soc. 124:11608-9
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 11608-9
-
-
Moon, H.S.1
Jacobson, E.M.2
Khersonsky, S.M.3
Luzung, M.R.4
Walsh, D.P.5
-
126
-
-
0036583926
-
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
-
Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, et al. 2002. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell. Proteomics 1:376-86
-
(2002)
Mol. Cell. Proteomics
, vol.1
, pp. 376-386
-
-
Ong, S.E.1
Blagoev, B.2
Kratchmarova, I.3
Kristensen, D.B.4
Steen, H.5
-
127
-
-
19944432197
-
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
-
Ross PL,HuangYN,Marchese JN, WilliamsonB,ParkerK, et al. 2004. Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol. Cell. Proteomics 3:1154-69
-
(2004)
Mol. Cell. Proteomics
, vol.3
, pp. 1154-1169
-
-
Ross, P.L.1
Huang, Y.N.2
Marchese, J.N.3
Williamson, B.4
Parker, K.5
-
128
-
-
0036737213
-
2,3,7,8-tetrachlorodibenzo-pdioxin toxicity in the zebrafish embryo: Local circulation failure in the dorsal midbrain is associated with increased apoptosis
-
Dong W, Teraoka H, Yamazaki K, Tsukiyama S, Imani S, et al. 2002. 2,3,7,8-tetrachlorodibenzo-pdioxin toxicity in the zebrafish embryo: local circulation failure in the dorsal midbrain is associated with increased apoptosis. Toxicol. Sci. 69:191-201
-
(2002)
Toxicol. Sci.
, vol.69
, pp. 191-201
-
-
Dong, W.1
Teraoka, H.2
Yamazaki, K.3
Tsukiyama, S.4
Imani, S.5
-
129
-
-
44649196430
-
Use of non-mammalian alternative models for neurotoxicological study
-
Peterson RT, Nass R, Boyd WA, Freedman JH, Dong K, Narahashi T. 2008. Use of non-mammalian alternative models for neurotoxicological study. Neurotoxicology 29:546-55
-
(2008)
Neurotoxicology
, vol.29
, pp. 546-555
-
-
Peterson, R.T.1
Nass, R.2
Boyd, W.A.3
Freedman, J.H.4
Dong, K.5
Narahashi, T.6
-
130
-
-
48349111923
-
The zebrafish embryomodel in environmental risk assessment-applications beyond acute toxicity testing
-
Scholz S, Fischer S, GundelU, Kuster E, Luckenbach T, VoelkerD. 2008. The zebrafish embryomodel in environmental risk assessment-applications beyond acute toxicity testing. Environ. Sci. Pollut. Res. Int. 15:394-404
-
(2008)
Environ. Sci. Pollut. Res. Int.
, vol.15
, pp. 394-404
-
-
Scholz, S.1
Fischer, S.2
Gundel, U.3
Kuster, E.4
Luckenbach, T.5
Voelker, D.6
-
131
-
-
34447122644
-
Pharmacogenomics: Challenges and opportunities
-
Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, et al. 2006. Pharmacogenomics: challenges and opportunities. Ann. Intern. Med. 145:749-57 (Pubitemid 351650355)
-
(2006)
Annals of Internal Medicine
, vol.145
, Issue.10
, pp. 749-757
-
-
Roden, D.M.1
Altman, R.B.2
Benowitz, N.L.3
Flockhart, D.A.4
Giacomini, K.M.5
Johnson, J.A.6
Krauss, R.M.7
McLeod, H.L.8
Ratain, M.J.9
Relling, M.V.10
Ring, H.Z.11
Shuldiner, A.R.12
Weinshilboum, R.M.13
Weiss, S.T.14
-
132
-
-
4644285301
-
Strain-dependent effects of developmental ethanol exposure in zebrafish
-
DOI 10.1016/j.ntt.2004.06.017, PII S0892036204000959
-
Loucks E, Carvan MJ, 3rd. 2004. Strain-dependent effects of developmental ethanol exposure in zebrafish. Neurotoxicol. Teratol. 26:745-55 (Pubitemid 39296759)
-
(2004)
Neurotoxicology and Teratology
, vol.26
, Issue.6 SPEC. ISS.
, pp. 745-755
-
-
Loucks, E.1
Carvan III, M.J.2
|