Glycemic memory

Current Opinion in Lipidology

Volumn 23, Issue 1, 2012, Pages 24-29

  El Osta, Assam ^a,b,c  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

chromatin; diabetic vascular complications; epigenetic; histones; hyperglycemic memory; methylation

Indexed keywords

GLYOXALASE; HEXOSAMINE; HISTONE DEACETYLASE; HISTONE H3; LYSINE; PROTEIN KINASE C; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SYNAPTOTAGMIN I;

BLOOD GLUCOSE MONITORING; CELL METABOLISM; CHROMATIN; DIABETIC PATIENT; DIABETIC RETINOPATHY; DNA REPAIR; DNA REPLICATION; ELECTRON TRANSPORT; EPIGENETICS; GENETIC REGULATION; GENOME; GLYCEMIC CONTROL; HISTONE METHYLATION; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MEMORY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; BLOOD GLUCOSE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONES; HUMANS; HYPERGLYCEMIA; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE OXYGEN SPECIES;

EID: 84855858220     PISSN: 09579672     EISSN: 14736535     Source Type: Journal    
DOI: 10.1097/MOL.0b013e32834f319d     Document Type: Review

References (52)

1. Gotzsche O, Gundersen HJ, Osterby R. Irreversibility of glomerular basement membrane accumulation despite reversibility of renal hypertrophy with islet transplantation in early experimental diabetes. Diabetes 1981; 30:481-485. (Pubitemid 11023367)
2. Engerman RL, Kern TS. Progression of incipient diabetic retinopathy during good glycemic control. Diabetes 1987; 36:808-812. (Pubitemid 17145301)
3. Roy S, Sala R, Cagliero E, Lorenzi M. Overexpression of fibronectin induced by diabetes or high glucose: phenomenon with a memory. Proc Natl Acad Sci USA 1990; 87:404-408.
4. Brown A, Reynolds LR, Bruemmer D. Intensive glycemic control and cardiovascular disease: an update. Nat Rev Cardiol 2010; 7:369-375.
5. Chalmers J, Cooper ME. UKPDS and the legacy effect. N Engl J Med 2008; 359:1618-1620.
6. Writing Team for the Diabetes Control and Complications Trial EoDIaCRG. Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the epidemiology of diabetes interventions and complications (EDIC) study. JAMA 2003; 290:2159-2167.
7. Nathan DM, Cleary PA, Backlund JY, et al. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005; 353:2643-2653. (Pubitemid 41817713)
8. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of longterm complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329:977-986.
9. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med 2000; 342:381-389.
10. Ceriello A, Ihnat MA, Thorpe JE. Clinical review 2: the 'metabolic memory'-is more than just tight glucose control necessary to prevent diabetic complications? J Clin Endocrinol Metab 2009; 94:410-415.
11. Ihnat MA, Thorpe JE, Kamat CD, et al. Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling. Diabetologia 2007; 50:1523-1531. (Pubitemid 46879013)
12. Holman RR, Paul SK, Bethel MA, et al. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008; 359:1577-1589.
13. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352:837-853.
14. Patel A, MacMahon S, Chalmers J, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358:2560-2572. (Pubitemid 351831357)
15. Gerstein HC, Miller ME, Byington RP, et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008; 358:2545-2559. (Pubitemid 351831356)
16. Duckworth W, Abraira C, Moritz T, et al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009; 360:129-139.
17. Ismail-Beigi F, Moghissi E, Tiktin M, et al. Individualizing glycemic targets in type 2 diabetes mellitus: implications of recent clinical trials. Ann Intern Med 2011; 154:554-559.
18. Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010; 107:1058-1070.
19. Yao D, Brownlee M. Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands. Diabetes 2010; 59:249-255.
20. El-Osta A, Brasacchio D, Yao D, et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med 2008; 205:2409-2417.
21. Brasacchio D, Okabe J, Tikellis C, et al. Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes 2009; 58:1229-1236.
22. Zhong Q, Kowluru RA. Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy. Diabetes 2011; 60:1304-1313.
23. Metzger E, Schule R. The expanding world of histone lysine demethylases. Nat Struct Mol Biol 2007; 14:252-254. (Pubitemid 46608329)
24. Trojer P, Reinberg D. Histone lysine demethylases and their impact on epigenetics. Cell 2006; 125:213-217.
25. Metzger E, Wissmann M, Yin N, et al. LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 2005; 437:436-439. (Pubitemid 41613508)
26. Shi Y, Lan F, Matson C, et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004; 119:941-953. (Pubitemid 40037608)
27. Wissmann M, Yin N, Muller JM, et al. Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol 2007; 9:347-353.
28. Tsukada Y, Fang J, Erdjument-Bromage H, et al. Histone demethylation by a family of JmjC domain-containing proteins. Nature 2006; 439:811-816. (Pubitemid 43255695)
29. Shi Y, Sawada J, Sui G, et al. Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature 2003; 422:735-738. (Pubitemid 36514114)
30. Lan F, Zaratiegui M, Villen J, et al. S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Mol Cell 2007; 26:89-101. (Pubitemid 46550935)
31. Klose RJ, Yamane K, Bae Y, et al. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature 2006; 442:312-316. (Pubitemid 44114907)
32. Yamane K, Toumazou C, Tsukada Y, et al. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 2006; 125:483-495.
33. Tateishi K, Okada Y, Kallin EM, Zhang Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 2009; 458:757-761.
34. Cooper ME, El-Osta A. Epigenetics: mechanisms and implications for diabetic complications. Circ Res 2010; 107:1403-1413.
35. Villeneuve LM, Kato M, Reddy MA, et al. Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes 2010; 59:2904-2915.
36. Pirola L, Balcerczyk A, Tothill RW, et al. Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells. Genome Res 2011; 21:1601-1615.
37. Feinberg AP, Irizarry RA, Fradin D, et al. Personalized epigenomic signatures that are stable over time and covary with body mass index. Sci Transl Med 2010; 2:49ra67.
38. Jufvas A, Stralfors P, Vener AV. Histone variants and their posttranslational modifications in primary human fat cells. PLoS One 2011; 6:e15960.
39. VilleneuveLM, Reddy MA, Lanting LL, et al. Epigenetic histoneH3lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proc Natl Acad Sci USA 2008; 105:9047-9052.
40. Miao F, Smith DD, Zhang L, et al. Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes. Diabetes 2008; 57:3189-3198.
41. Miao F, Wu X, Zhang L, et al. Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes. J Immunol 2008; 180:2264-2269.
42. Miao F, Wu X, Zhang L, et al. Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. J Biol Chem 2007; 282:13854-13863. (Pubitemid 47100501)
43. Wang B, Moya N, Niessen S, et al. A hormone-dependent module regulating energy balance. Cell 2011; 145:596-606.
44. Mihaylova MM, Vasquez DS, Ravnskjaer K, et al. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell 2011; 145:607-621.
45. Baker KD, Thummel CS. Diabetic larvae and obese flies-emerging studies of metabolism in drosophila. Cell Metab 2007; 6:257-266. (Pubitemid 47450188)
46. Hawkins RD, Hon GC, Ren B. Next-generation genomics: an integrative approach. Nat Rev Genet 2010; 11:476-486.
47. Syreeni A, El-Osta A, Forsblom C, et al. Genetic Examination of SETD7 and SUV39H1/H2 methyltransferases and the risk of diabetes complications in patients with type 1 diabetes. Diabetes 2011; 60:3073-3080.
48. Nikoshkov A, Sunkari V, Savu O, et al. Epigenetic DNA methylation in the promoters of the Igf1 receptor and insulin receptor genes in db/db mice. Epigenetics 2011; 6:405-409.
49. Sapienza C, Lee J, Powell J, et al. DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy. Epigenetics 2011; 6:20-28.
50. Greer EL, Maures TJ, Ucar D, et al. Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature 2011; 479:365-371.
51. Greer EL, Maures TJ, Hauswirth AG, et al. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature 2010; 466:383-387.
52. Jin C, Li J, Green CD, et al. Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab 2011; 14:161-172.