-
2
-
-
0029780526
-
The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications
-
Fauman, E.B.; Yuvaniyama, C.; Schubert, H.L.; Stuckey, J.A.; Saper, M.A. The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications. J. Biol. Chem., 1996, 271(31), 18780-18788.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.31
, pp. 18780-18788
-
-
Fauman, E.B.1
Yuvaniyama, C.2
Schubert, H.L.3
Stuckey, J.A.4
Saper, M.A.5
-
3
-
-
0030296869
-
Molecular mechanisms of the protein serine/threonine phosphatases
-
Barford, D. Molecular mechanisms of the protein serine/threonine phosphatases. Trends Biochem. Sci., 1996, 21(11), 407-412.
-
(1996)
Trends Biochem. Sci.
, vol.21
, Issue.11
, pp. 407-412
-
-
Barford, D.1
-
4
-
-
0031860103
-
The structure and mechanism of protein phosphatases: Insights into catalysis and regulation
-
Barford, D.; Das, A.K.; Egloff, M.P. The structure and mechanism of protein phosphatases: insights into catalysis and regulation. Annu. Rev. Biophys. Biomol. Struct., 1998, 27, 133-164.
-
(1998)
Annu. Rev. Biophys. Biomol. Struct
, vol.27
, pp. 133-164
-
-
Barford, D.1
Das, A.K.2
Egloff, M.P.3
-
5
-
-
0030297891
-
Form and function in protein dephosphorylation
-
Denu, J.M.; Stuckey, J.A.; Saper, M.A.; Dixon, J.E. Form and function in protein dephosphorylation. Cell, 1996, 87(3), 365-368.
-
(1996)
Cell
, vol.87
, Issue.3
, pp. 365-368
-
-
Denu, J.M.1
Stuckey, J.A.2
Saper, M.A.3
Dixon, J.E.4
-
6
-
-
0029583122
-
Crystal structure of the catalytic subunit of human protein phosphatase and its complex with tungstate
-
Egloff, M.P.; Cohen, P.T.; Reinemer, P.; Barford, D. Crystal structure of the catalytic subunit of human protein phosphatase and its complex with tungstate. J. Mol. Biol., 1995, 254(5), 942-959.
-
(1995)
J. Mol. Biol.
, vol.254
, Issue.5
, pp. 942-959
-
-
Egloff, M.P.1
Cohen, P.T.2
Reinemer, P.3
Barford, D.4
-
7
-
-
2942581416
-
Protein tyrosine phosphatases in the human genome
-
Alonso, A.; Sasin, J.; Bottini, N.; Friedberg, I.; Osterman, A.; Godzik, A.; Hunter, T.; Dixon, J.; Mustelin, T. Protein tyrosine phosphatases in the human genome. Cell, 2004, 117(6) 699-711.
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 699-711
-
-
Alonso, A.1
Sasin, J.2
Bottini, N.3
Friedberg, I.4
Osterman, A.5
Godzik, A.6
Hunter, T.7
Dixon, J.8
Mustelin, T.9
-
8
-
-
60549090245
-
Is Cdc25 a Druggable Target? Anticancer Agents
-
Lazo, J.S.; Wipf, P. Is Cdc25 a Druggable Target? Anticancer Agents Med. Chem., 2008, 8(8), 837-842.
-
(2008)
Med. Chem.
, vol.8
, Issue.8
, pp. 837-842
-
-
Lazo, J.S.1
Wipf, P.2
-
9
-
-
34848812587
-
What if higher plants lack a CDC25 phosphatase?
-
Boudolf, V., Inze, D.; De Veylder, L. What if higher plants lack a CDC25 phosphatase? Trends Plant Sci., 2006, 11(10), 474-479.
-
(2006)
Trends Plant Sci.
, vol.11
, Issue.10
, pp. 474-479
-
-
Boudolf, V.1
Inze, D.2
de Veylder, L.3
-
10
-
-
0026319225
-
Specific activation of Cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
-
Galaktionov, K.; Beach, D. Specific activation of Cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell, 1991, 67(6), 1181-1194.
-
(1991)
Cell
, vol.67
, Issue.6
, pp. 1181-1194
-
-
Galaktionov, K.1
Beach, D.2
-
11
-
-
0025324692
-
Human homolog of fission yeast Cdc25 mitotic inducer is predominantly expressed in G2
-
Sadhu, K.; Reed, S.I.; Richardson, H.; Russell, P. Human homolog of fission yeast Cdc25 mitotic inducer is predominantly expressed in G2. Proc. Natl. Acad. Sci. USA, 1990, 87(13), 5139-5143.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, Issue.13
, pp. 5139-5143
-
-
Sadhu, K.1
Reed, S.I.2
Richardson, H.3
Russell, P.4
-
12
-
-
0026234297
-
An additional homolog of the fission yeast Cdc25 gene occurs in humans and is highly expressed in some cancer cells
-
Nagata, A.; Igarashi, M.; Jinno, S.; Suto, K.; Okayama, H. An additional homolog of the fission yeast Cdc25 gene occurs in humans and is highly expressed in some cancer cells. New Biol. 1991, 3(10), 959-968.
-
(1991)
New Biol
, vol.3
, Issue.10
, pp. 959-968
-
-
Nagata, A.1
Igarashi, M.2
Jinno, S.3
Suto, K.4
Okayama, H.5
-
13
-
-
0033646929
-
Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C
-
Wegener, S.; Hampe, W.; Herrmann, D.; Schaller, H.C. Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C. Eur. J. Cell Biol., 2000, 79(11), 810-815.
-
(2000)
Eur. J. Cell Biol.
, vol.79
, Issue.11
, pp. 810-815
-
-
Wegener, S.1
Hampe, W.2
Herrmann, D.3
Schaller, H.C.4
-
14
-
-
0030919764
-
Alternative splicing of the human CDC25B tyrosine phoshatase. Possible implications for growth control?
-
Baldin, V.; Cans, C.; Superti-Furga, G.; Ducommun, B. Alternative splicing of the human CDC25B tyrosine phoshatase. Possible implications for growth control? Oncogene, 1997, 14(20), 2485-2495.
-
(1997)
Oncogene
, vol.14
, Issue.20
, pp. 2485-2495
-
-
Baldin, V.1
Cans, C.2
Superti-Furga, G.3
Ducommun, B.4
-
15
-
-
0033526819
-
Multiple splicing variants of Cdc25B regulate G2/M progression
-
Forrest, A.R.; McCormack, A.K.; De Souza, C.P.; Sinnamon, J.M.; Tonks, I.D.; Hayward, N.K.; Ellem, K.A.; Gabrielli, B.G. Multiple splicing variants of Cdc25B regulate G2/M progression. Biochem. Biophys. Res. Commun., 1999, 260(2), 510-515.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.260
, Issue.2
, pp. 510-515
-
-
Forrest, A.R.1
McCormack, A.K.2
de Souza, C.P.3
Sinnamon, J.M.4
Tonks, I.D.5
Hayward, N.K.6
Ellem, K.A.7
Gabrielli, B.G.8
-
16
-
-
60549094422
-
Cell Cycle Control by the CDC25 Phosphatases. Anti-Cancer Agents
-
Aressy, B.; Ducommun B. Cell Cycle Control by the CDC25 Phosphatases. Anti-Cancer Agents Med. Chem., 2008, 8(8), 818-824.
-
(2008)
Med. Chem.
, vol.8
, Issue.8
, pp. 818-824
-
-
Aressy, B.1
Ducommun, B.2
-
17
-
-
0034543444
-
An additional transcript of the cdc25C gene from A431 cells encodes a functional protein
-
Bureik, M.; Rief, N.; Drescher, R.; Jungbluth, A.; Montenarh, M.; Wagner, P. An additional transcript of the cdc25C gene from A431 cells encodes a functional protein. Int. J. Oncol., 2000, 17(6), 1251-1258.
-
(2000)
Int. J. Oncol.
, vol.17
, Issue.6
, pp. 1251-1258
-
-
Bureik, M.1
Rief, N.2
Drescher, R.3
Jungbluth, A.4
Montenarh, M.5
Wagner, P.6
-
18
-
-
27644480747
-
Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer
-
Ozen M, Ittmann M. Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer. Clin. Cancer Res., 2005, 11(13), 4701-4706
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.13
, pp. 4701-4706
-
-
Ozen, M.1
Ittmann, M.2
-
19
-
-
0028314952
-
Cdc25A is a novel phosphatase functioning early in the cell cycle
-
Jinno, S.; Suto, K.; Nagata, A.; Igashari, M.; Kanaoka, Y.; Nojima, H.; Okayama, H. Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J., 1994, 13(7), 1549-1556.
-
(1994)
EMBO J.
, vol.13
, Issue.7
, pp. 1549-1556
-
-
Jinno, S.1
Suto, K.2
Nagata, A.3
Igashari, M.4
Kanaoka, Y.5
Nojima, H.6
Okayama, H.7
-
20
-
-
34250865564
-
CDC25 phosphatases in cancer cells:Key players? Good targets?
-
Boutros, R.; Lobjois V.; Ducommun, B. CDC25 phosphatases in cancer cells:key players? Good targets? Nat. Rev. Cancer, 2007, 7(7), 495-507.
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.7
, pp. 495-507
-
-
Boutros, R.1
Lobjois, V.2
Ducommun, B.3
-
21
-
-
33947646873
-
Cdc25 phosphatases: Structure, specificity, and mechanism
-
Rudolph, J. Cdc25 phosphatases: structure, specificity, and mechanism. Biochemistry, 2007, 46(12), 3595-3604.
-
(2007)
Biochemistry
, vol.46
, Issue.12
, pp. 3595-3604
-
-
Rudolph, J.1
-
22
-
-
0033538847
-
Cdc25b and Cdc25c Differ Markedly in Their Properties as Initiators of Mitosis
-
Karlsson, C.; Katich, S.; Hagting, A.; Hoffmann, I.; Pines, J.J. Cdc25b and Cdc25c Differ Markedly in Their Properties as Initiators of Mitosis. Cell Biol., 1999, 146(3), 573-584.
-
(1999)
Cell Biol.
, vol.146
, Issue.3
, pp. 573-584
-
-
Karlsson, C.1
Katich, S.2
Hagting, A.3
Hoffmann, I.4
Pines, J.J.5
-
23
-
-
0034232093
-
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis
-
Molinari, M.; Mercurio, C.; Dominguez, J.; Goubin, F.; Draetta, G.F. Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis. EMBO Rep., 2000, 1, 71-79.
-
(2000)
EMBO Rep
, vol.1
, pp. 71-79
-
-
Molinari, M.1
Mercurio, C.2
Dominguez, J.3
Goubin, F.4
Draetta, G.F.5
-
24
-
-
33644856152
-
The when and wheres of CDC25 phosphatases
-
Boutros, R.; Dozier, C.; Ducommun, B. The when and wheres of CDC25 phosphatases. Curr. Opin. Cell Biol., 2006, 18(2),185-191.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, Issue.2
, pp. 185-191
-
-
Boutros, R.1
Dozier, C.2
Ducommun, B.3
-
25
-
-
33344476097
-
DNA damage checkpoints in mammals
-
Niida, H.; Nakanishi, M. DNA damage checkpoints in mammals. Mutagenesis, 2006, 21, 3-9.
-
(2006)
Mutagenesis
, vol.21
, pp. 3-9
-
-
Niida, H.1
Nakanishi, M.2
-
26
-
-
4344718628
-
Cdc25 phosphatases and cancer
-
Kristjánsdóttir, K.; Rudolph, J. Cdc25 phosphatases and cancer. Chem. Biol., 2004, 11(8), 1043-1051.
-
(2004)
Chem. Biol.
, vol.11
, Issue.8
, pp. 1043-1051
-
-
Kristjánsdóttir, K.1
Rudolph, J.2
-
27
-
-
0037421958
-
Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer
-
Ngan, E.S.; Hashimoto, Y.; Ma, Z.Q.; Tsai, M.J.; Tsai, S.Y. Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer. Oncogene, 2003, 22(5), 734-739.
-
(2003)
Oncogene
, vol.22
, Issue.5
, pp. 734-739
-
-
Ngan, E.S.1
Hashimoto, Y.2
Ma, Z.Q.3
Tsai, M.J.4
Tsai, S.Y.5
-
28
-
-
0033796031
-
Role of the Cdc25A phosphatase in human breast cancer
-
Cangi, M.G.; Cukor, B.; Soung, P.; Signoretti, S.; Moreira, G. Jr.; Ranashinge, M.; Cady, B.; Pagano, M.; Loda, M. Role of the Cdc25A phosphatase in human breast cancer. J. Clin. Invest., 2000, 106(6), 753-61.
-
(2000)
J. Clin. Invest.
, vol.106
, Issue.6
, pp. 753-761
-
-
Cangi, M.G.1
Cukor, B.2
Soung, P.3
Signoretti, S.4
Moreira Jr., G.5
Ranashinge, M.6
Cady, B.7
Pagano, M.8
Loda, M.9
-
29
-
-
77952484477
-
Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes
-
Wang, Z.; Trope, C.G.; Flørenes, V.A.; Suo, Z.; Nesland, J.M.; Holm, R. Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes. BMC Cancer, 2010, 10, 233.
-
(2010)
BMC Cancer
, vol.10
, pp. 233
-
-
Wang, Z.1
Trope, C.G.2
Flørenes, V.A.3
Suo, Z.4
Nesland, J.M.5
Holm, R.6
-
30
-
-
0034688873
-
Cdc25a and the splicing variant Cdc25b2, but not Cdc25B1,-B3 or-C, are over-expressed in aggressive human non-Hodgkin's lymphomas
-
Hernández, S.; Hernández, L.; Bea, S.; Pinyol, M.; Nayach, I., Bellosillo, B.; Nadal, A.; Ferrer, A.; Fernandez, P.L.; Montserrat, E.; Cardesa, A.; Campo, E. Cdc25a and the splicing variant Cdc25b2, but not Cdc25B1,-B3 or-C, are over-expressed in aggressive human non-Hodgkin's lymphomas. Int. J. Cancer, 2000, 89(2), 148-52.
-
(2000)
Int. J. Cancer
, vol.89
, Issue.2
, pp. 148-152
-
-
Hernández, S.1
Hernández, L.2
Bea, S.3
Pinyol, M.4
Nayach, I.5
Bellosillo, B.6
Nadal, A.7
Ferrer, A.8
Fernandez, P.L.9
Montserrat, E.10
Cardesa, A.11
Campo, E.12
-
31
-
-
0027423987
-
Amino acid sequence similarity between CL100, a dual-specificity MAP kinase phosphatase and Cdc25
-
Keyse S.M.; Ginsburg, M. Amino acid sequence similarity between CL100, a dual-specificity MAP kinase phosphatase and Cdc25. Trends Biochem. Sci., 1993, 18(10), 377-378.
-
(1993)
Trends Biochem. Sci.
, vol.18
, Issue.10
, pp. 377-378
-
-
Keyse, S.M.1
Ginsburg, M.2
-
32
-
-
33846388965
-
Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase
-
Sohn, J.; Buhrman, G.; Rudolph, J. Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase. Biochemistry, 2007, 46(3), 807-818.
-
(2007)
Biochemistry
, vol.46
, Issue.3
, pp. 807-818
-
-
Sohn, J.1
Buhrman, G.2
Rudolph, J.3
-
33
-
-
16844367916
-
Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond
-
Buhrman, G.K.; Parker, B.; Sohn, J.; Rudolph, J.; Mattos, C. Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond. Biochemistry, 2005, 44(20), 5307-5316.
-
(2005)
Biochemistry
, vol.44
, Issue.20
, pp. 5307-5316
-
-
Buhrman, G.K.1
Parker, B.2
Sohn, J.3
Rudolph, J.4
Mattos, C.5
-
34
-
-
18144432725
-
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
-
Fauman, E.B.; Cogswell, J.P.; Lovejoy, B.; Rocque, W.J.; Holmes, W.; Montana, V. G.; Piwnica-Worms, H.; Rink, M.J.; Saper, M.A. Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A. Cell, 1998, 93(4), 617-625.
-
(1998)
Cell
, vol.93
, Issue.4
, pp. 617-625
-
-
Fauman, E.B.1
Cogswell, J.P.2
Lovejoy, B.3
Rocque, W.J.4
Holmes, W.5
Montana, V.G.6
Piwnica-Worms, H.7
Rink, M.J.8
Saper, M.A.9
-
35
-
-
0032738102
-
Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle
-
Reynolds, R. A.; Yem, A. W.; Wolfe, C. L.; Deibel, M. R. Jr; Chidester, C. G.; Watenpaugh, K. D. Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle. J. Mol. Biol., 1999, 293(3), 559-68.
-
(1999)
J. Mol. Biol.
, vol.293
, Issue.3
, pp. 559-568
-
-
Reynolds, R.A.1
Yem, A.W.2
Wolfe, C.L.3
Deibel Jr., M.R.4
Chidester, C.G.5
Watenpaugh, K.D.6
-
36
-
-
9344254385
-
Remote hot spots mediate protein substrate recognition for the Cdc25 phosphatase
-
Sohn, J.; Kristjansdottir, K.A.; Safi, B.; Parker, B.; Kiburz; Rudolph, J. Remote hot spots mediate protein substrate recognition for the Cdc25 phosphatase. Proc Natl Acad Sci U S A., 2004, 101(47),16437-16441.
-
(2004)
Proc Natl Acad Sci U S A.
, vol.101
, Issue.47
, pp. 16437-16441
-
-
Sohn, J.1
Kristjansdottir, K.A.2
Safi, B.3
Parker, B.4
Kiburz5
Rudolph, J.6
-
37
-
-
0036773411
-
Quantification of protein surfaces, volumes and atom-atom contacts using a constrained Voronoi procedure
-
McConkey, B.J.; Sobolev, V.; Edelman, M. Quantification of protein surfaces, volumes and atom-atom contacts using a constrained Voronoi procedure. Bioinformatics, 2002, 18(10), 1365-1373.
-
(2002)
Bioinformatics
, vol.18
, Issue.10
, pp. 1365-1373
-
-
McConkey, B.J.1
Sobolev, V.2
Edelman, M.3
-
38
-
-
58149250722
-
Toward a Molecular Understanding of the Interaction of Dual Specificity Phosphatases with Substrates: Insights from Structure-Based Modeling and High Throughput Screening
-
Bakan, A.; Lazo J.S.; Wipf, P.; Brummond, K.M.; Bahar, I. Toward a Molecular Understanding of the Interaction of Dual Specificity Phosphatases with Substrates: Insights from Structure-Based Modeling and High Throughput Screening. Curr. Med. Chem. 2008, 15(25), 2536-2544.
-
(2008)
Curr. Med. Chem
, vol.15
, Issue.25
, pp. 2536-2544
-
-
Bakan, A.1
Lazo, J.S.2
Wipf, P.3
Brummond, K.M.4
Bahar, I.5
-
39
-
-
77957946203
-
Flexibility and inhibitor binding in Cdc25 phosphatases
-
Arantes, G.M. Flexibility and inhibitor binding in Cdc25 phosphatases. Proteins, 2010, 78(14), 3017-3032.
-
(2010)
Proteins
, vol.78
, Issue.14
, pp. 3017-3032
-
-
Arantes, G.M.1
-
40
-
-
0035935711
-
Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25
-
Lazo, J.S.; Aslan, D.C.; Southwick, E.C.; Cooley, K.A.; Ducruet, A.P.; Joo, B.; Vogt, A.; Wipf, P. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J. Med. Chem., 2001, 44(24), 4042-4049.
-
(2001)
J. Med. Chem.
, vol.44
, Issue.24
, pp. 4042-4049
-
-
Lazo, J.S.1
Aslan, D.C.2
Southwick, E.C.3
Cooley, K.A.4
Ducruet, A.P.5
Joo, B.6
Vogt, A.7
Wipf, P.8
-
41
-
-
0037777745
-
Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones
-
Sohn, J.; Kiburz, B.; Li, Z.; Deng, L.; Safi, A.; Pirrung, M.C.; Rudolph, J. Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones. J. Med. Chem., 2003, 46(13), 2580-2588.
-
(2003)
J. Med. Chem.
, vol.46
, Issue.13
, pp. 2580-2588
-
-
Sohn, J.1
Kiburz, B.2
Li, Z.3
Deng, L.4
Safi, A.5
Pirrung, M.C.6
Rudolph, J.7
-
42
-
-
0035935711
-
Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25
-
Lazo, J.S.; Aslan, D.C.; Southwick, E.C.; Cooley, K.A.; Ducruet, A.P.; Joo, B.; Vogt, A.; Wipf, P. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J. Med. Chem., 2001, 44(24), 4042-4049.
-
(2001)
J. Med. Chem.
, vol.44
, Issue.24
, pp. 4042-4049
-
-
Lazo, J.S.1
Aslan, D.C.2
Southwick, E.C.3
Cooley, K.A.4
Ducruet, A.P.5
Joo, B.6
Vogt, A.7
Wipf, P.8
-
43
-
-
33847235757
-
Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases
-
Brault, L.; Denancé, M.; Banaszak, E.; Maadidi, S. E.; Battaglia, E.; Bagrel, D.; Samadi, M. Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases. Eur. J. Med. Chem., 2007, 42(2), 243-247.
-
(2007)
Eur. J. Med. Chem.
, vol.42
, Issue.2
, pp. 243-247
-
-
Brault, L.1
Denancé, M.2
Banaszak, E.3
Maadidi, S.E.4
Battaglia, E.5
Bagrel, D.6
Samadi, M.7
-
44
-
-
33144467432
-
Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases
-
Huang, W.; Li, J.; Zhang, W.; Zhou, Y.; Xie, C.; Luo, Y.; Li, Y.; Wang, J.; Li, J.; Lu, W. Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases. Bioorg. Med. Chem. Lett., 2006, 16(7), 1905-1908.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, Issue.7
, pp. 1905-1908
-
-
Huang, W.1
Li, J.2
Zhang, W.3
Zhou, Y.4
Xie, C.5
Luo, Y.6
Li, Y.7
Wang, J.8
Li, J.9
Lu, W.10
-
45
-
-
18344375627
-
Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors
-
Lazo, J.S.; Nemoto, K.; Pestell, K.E.; Cooley, K.; Southwick, E.C.; Mitchell, D.A.; Furey, W.; Gussio, R.; Zaharevitz, D.W.; Joo, B.; Wipf, P. Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Mol. Pharmacol., 2002, 61(4), 720-728.
-
(2002)
Mol. Pharmacol.
, vol.61
, Issue.4
, pp. 720-728
-
-
Lazo, J.S.1
Nemoto, K.2
Pestell, K.E.3
Cooley, K.4
Southwick, E.C.5
Mitchell, D.A.6
Furey, W.7
Gussio, R.8
Zaharevitz, D.W.9
Joo, B.10
Wipf, P.11
-
46
-
-
33646776011
-
Modeling of Cdc25B dual specifity protein phosphatase inhibitors: Docking of ligands and enzymatic inhibition mechanism
-
Lavecchia, A.; Cosconati, S.; Limongelli, V.; Novellino, E. Modeling of Cdc25B dual specifity protein phosphatase inhibitors: docking of ligands and enzymatic inhibition mechanism. Chem. Med. Chem. 2006, 1(5), 540-550.
-
(2006)
Chem. Med. Chem
, vol.1
, Issue.5
, pp. 540-550
-
-
Lavecchia, A.1
Cosconati, S.2
Limongelli, V.3
Novellino, E.4
-
47
-
-
52449110024
-
Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening
-
Park, H.; Bahn, Y. J.; Jung, S.-K.; Jeong, D. G.; Lee, S.-H.; Seo, I.; Yoon, T.-S.; Kim, S. J.; Ryu, S. E. Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening. J. Med. Chem. 2008, 51(18), 5533-5541.
-
(2008)
J. Med. Chem
, vol.51
, Issue.18
, pp. 5533-5541
-
-
Park, H.1
Bahn, Y.J.2
Jung, S.-K.3
Jeong, D.G.4
Lee, S.-H.5
Seo, I.6
Yoon, T.-S.7
Kim, S.J.8
Ryu, S.E.9
-
48
-
-
60549090062
-
Cdc25B phosphatase inhibitors in cancer therapy: Latest developments, trends and medicinal chemistry perspective
-
Lavecchia A, Coluccia A, Di Giovanni C, Novellino E. Cdc25B phosphatase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective. Anticancer Agents Med. Chem., 2008, 8(8), 843-856.
-
(2008)
Anticancer Agents Med. Chem.
, vol.8
, Issue.8
, pp. 843-856
-
-
Lavecchia, A.1
Coluccia, A.2
Di Giovanni, C.3
Novellino, E.4
-
49
-
-
68449102462
-
CDC25A and B dualspecificity phosphatase inhibitors: Potential agents for cancer therapy
-
Lavecchia A, Di Giovanni C, Novellino E. CDC25A and B dualspecificity phosphatase inhibitors: potential agents for cancer therapy. Curr. Med. Chem. 2009, 16(15):1831-1849.
-
(2009)
Curr. Med. Chem
, vol.16
, Issue.15
, pp. 1831-1849
-
-
Lavecchia, A.1
Di Giovanni, C.2
Novellino, E.3
-
50
-
-
77649085550
-
Inhibitors of Cdc25 phosphatases as anticancer agents: A patent review. Expert Opin
-
Lavecchia A, Di Giovanni C, Novellino E. Inhibitors of Cdc25 phosphatases as anticancer agents: a patent review. Expert Opin. Ther. Pat., 2010, 20(3), 405-425.
-
(2010)
Ther. Pat.
, vol.20
, Issue.3
, pp. 405-425
-
-
Lavecchia, A.1
Di Giovanni, C.2
Novellino, E.3
-
51
-
-
70249108449
-
LGH00031, a novel ortho-quinonoid inhibitor of cell division cycle 25B, inhibits human cancer cells via ROS generation
-
Zhou, Y.B.; Feng, X.; Wang, L.N.; Du, J.Q.; Zhou, Y.Y.; Yu, H.P.; Zang, Y.; Li, J.Y.; Li, J. LGH00031, a novel ortho-quinonoid inhibitor of cell division cycle 25B, inhibits human cancer cells via ROS generation. Acta Pharmacol. Sin., 2009, 30(9):1359-1368.
-
(2009)
Acta Pharmacol. Sin.
, vol.30
, Issue.9
, pp. 1359-1368
-
-
Zhou, Y.B.1
Feng, X.2
Wang, L.N.3
Du, J.Q.4
Zhou, Y.Y.5
Yu, H.P.6
Zang, Y.7
Li, J.Y.8
Li, J.9
-
52
-
-
67649934675
-
Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitors
-
Park, H.;. Bahn, Y.J.; Ryu, S.E. Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitors. Bioorg. Med. Chem. Lett., 2009, 19(15), 4330-4334.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, Issue.15
, pp. 4330-4334
-
-
Park, H.1
Bahn, Y.J.2
Ryu, S.E.3
-
53
-
-
52449110024
-
Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening
-
Park, H.; Bahn, Y. J.; Jung, S.-K.; Jeong, D. G.; Lee, S.-H.; Seo, I.; Yoon, T.-S.; Kim, S. J.; Ryu, S. E. Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening. J. Med. Chem., 2008, 51(18), 5533-5541.
-
(2008)
J. Med. Chem.
, vol.51
, Issue.18
, pp. 5533-5541
-
-
Park, H.1
Bahn, Y.J.2
Jung, S.-K.3
Jeong, D.G.4
Lee, S.-H.5
Seo, I.6
Yoon, T.-S.7
Kim, S.J.8
Ryu, S.E.9
-
54
-
-
39449138498
-
Receptor-based virtual ligand screening for the identification of novel CDC25 phosphatase inhibitors
-
Montes, M.; Braud, E.; Miteva, M.A.; Goddard, M.L.; Mondésert, O.; Kolb, S.; Brun, M.P.; Ducommun, B.; Garbay, C.; Villoutreix, B.O. J. Receptor-based virtual ligand screening for the identification of novel CDC25 phosphatase inhibitors. Chem. Inf. Model. 2008, 48(1), 157-165.
-
(2008)
Chem. Inf. Model
, vol.48
, Issue.1
, pp. 157-165
-
-
Montes, M.1
Braud, E.2
Miteva, M.A.3
Goddard, M.L.4
Mondésert, O.5
Kolb, S.6
Brun, M.P.7
Ducommun, B.8
Garbay, C.9
Villoutreix, B.O.J.10
-
55
-
-
65549135298
-
Development of novel thiazolopyrimidines as CDC25B phosphatase inhibitors
-
Kolb, S.; Mondesert, O.; Goddard, M. L.; Jullien, D.; Villoutreix, B. O.; Ducommun, B.; Garbay, C.; Braud, E Development of novel thiazolopyrimidines as CDC25B phosphatase inhibitors. Chem. Med. Chem. 2009, 4(4), 633-648.
-
(2009)
Chem. Med. Chem
, vol.4
, Issue.4
, pp. 633-648
-
-
Kolb, S.1
Mondesert, O.2
Goddard, M.L.3
Jullien, D.4
Villoutreix, B.O.5
Ducommun, B.6
Garbay, C.7
Braud, E.8
-
56
-
-
70449435021
-
Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ screening
-
Duval, R.; Kolb, S.; Braud, E.; Genest, D.; Garbay, C. Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ screening. J. Comb. Chem., 2009, 11(6), 947-950.
-
(2009)
J. Comb. Chem.
, vol.11
, Issue.6
, pp. 947-950
-
-
Duval, R.1
Kolb, S.2
Braud, E.3
Genest, D.4
Garbay, C.5
-
57
-
-
77957590019
-
Synthesis and biological evaluation of novel coumarin-based inhibitors of Cdc25 phosphatases
-
Valente, S.; Bana, E.; Viry, E.; Bagrel, D.; Kirsch, G. Synthesis and biological evaluation of novel coumarin-based inhibitors of Cdc25 phosphatases. Bioorg. Med. Chem. Lett., 2010, 20(19), 5827-5830.
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, Issue.19
, pp. 5827-5830
-
-
Valente, S.1
Bana, E.2
Viry, E.3
Bagrel, D.4
Kirsch, G.5
-
58
-
-
43949126193
-
Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells
-
Deep, G.; Oberlies, N. H.; Kroll, D. J.; Agarwal, R. Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells. Int. J. Cancer, 2008, 123(1), 41-50.
-
(2008)
Int. J. Cancer
, vol.123
, Issue.1
, pp. 41-50
-
-
Deep, G.1
Oberlies, N.H.2
Kroll, D.J.3
Agarwal, R.4
-
59
-
-
70350140452
-
Cdc25B Dual-Specificity Phosphatase Inhibitors Identified in a High-Throughput Screen of the NIH Compound Library. Assay Drug
-
Johnston, P.A.; Foster, C.A.; Tierno, M.B.; Shun, T.Y.; Shinde, S.N.; Paquette, W.D.; Brummond, K.M.; Wipf, P.; Lazo, J.S. Cdc25B Dual-Specificity Phosphatase Inhibitors Identified in a High-Throughput Screen of the NIH Compound Library. Assay Drug. Dev. Technol., 2009, 7(3), 250-265.
-
(2009)
Dev. Technol.
, vol.7
, Issue.3
, pp. 250-265
-
-
Johnston, P.A.1
Foster, C.A.2
Tierno, M.B.3
Shun, T.Y.4
Shinde, S.N.5
Paquette, W.D.6
Brummond, K.M.7
Wipf, P.8
Lazo, J.S.9
-
60
-
-
77950860029
-
Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B
-
Chen, H.J.; Liu, Y.; Wang, L.N.; Shen, Q.; Li, J.; Nan, F.J. Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B. Bioorg. Med. Chem. Lett., 2010, 20(9), 2876-2879.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, Issue.9
, pp. 2876-2879
-
-
Chen, H.J.1
Liu, Y.2
Wang, L.N.3
Shen, Q.4
Li, J.5
Nan, F.J.6
-
61
-
-
0035010504
-
Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia
-
Wardman, P. Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia. Curr. Med. Chem., 2001, 8(7) 739-761.
-
(2001)
Curr. Med. Chem
, vol.8
, Issue.7
, pp. 739-761
-
-
Wardman, P.1
-
62
-
-
0028868944
-
Growth inhibition of hepatoma cells induced by vitamin K and its analogs
-
Nishikawa, Y.; Carr, B. I.; Wang, M.; Kar, S.; Finn, F.; Dowd, P.; Zheng, Z. B.; Kerns, J.; Naganathan, S. J. Growth inhibition of hepatoma cells induced by vitamin K and its analogs. J. Biol. Chem., 1995, 270(47), 28304-28310.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.47
, pp. 28304-28310
-
-
Nishikawa, Y.1
Carr, B.I.2
Wang, M.3
Kar, S.4
Finn, F.5
Dowd, P.6
Zheng, Z.B.7
Kerns, J.8
Naganathan, S.J.9
-
63
-
-
3042594182
-
Fluorinated quinoid inhibitor: Possible "pure" arylator predicted by the simple theoretical calculation
-
Ham, S. W.; Choe, J. I.; Wang, M. F.; Peyregne, V.; Carr, B. I. Fluorinated quinoid inhibitor: possible "pure" arylator predicted by the simple theoretical calculation. Bioorg. Med. Chem. Lett. 2004, 14(15), 4103-4105.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, Issue.15
, pp. 4103-4105
-
-
Ham, S.W.1
Choe, J.I.2
Wang, M.F.3
Peyregne, V.4
Carr, B.I.5
-
64
-
-
33750215412
-
Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK
-
Kar, S.; Wang, M.; Ham, S. W.; Carr, B. I. Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK. Biochem. Pharmacol., 2006, 72(10), 1217-1227.
-
(2006)
Biochem. Pharmacol.
, vol.72
, Issue.10
, pp. 1217-1227
-
-
Kar, S.1
Wang, M.2
Ham, S.W.3
Carr, B.I.4
-
65
-
-
33947582226
-
Fluorinated NSC as a Cdc25 inhibitor
-
2354
-
Park, H.; Carr, B. I.; Li, M.; Ham, S. W. Fluorinated NSC as a Cdc25 inhibitor. Bioorg. Med. Chem. Lett., 2007, 17(8), 2351-2354.-2354
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, Issue.8
, pp. 2351-2354
-
-
Park, H.1
Carr, B.I.2
Li, M.3
Ham, S.W.4
-
66
-
-
77950860956
-
Cytotoxicity of new alkylamino-and phenylamino-containing polyfluorinated derivatives of 1,4-naphthoquinone
-
Zakharova, O.D.; Ovchinnikova, L.P.; Goryunov, L.I.; Troshkova, N.M.; Shteingarts, V.D.; Nevinsky, G.A. Cytotoxicity of new alkylamino-and phenylamino-containing polyfluorinated derivatives of 1,4-naphthoquinone. Eur. J. Med. Chem., 2010, 45(6), 2321-2326.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, Issue.6
, pp. 2321-2326
-
-
Zakharova, O.D.1
Ovchinnikova, L.P.2
Goryunov, L.I.3
Troshkova, N.M.4
Shteingarts, V.D.5
Nevinsky, G.A.6
-
67
-
-
72049102404
-
Cytotoxicity of new nbutylamino and sulfur-containing derivatives of polyfluorinated 1,4-naphthoquinone
-
Zakharova, O.D.; Ovchinnikova, L.P.; Goryunov, L.I.; Troshkova, N.M.; Shteingarts, V.D.; Nevinsky, G.A. Cytotoxicity of new nbutylamino and sulfur-containing derivatives of polyfluorinated 1,4-naphthoquinone. Eur. J. Med. Chem., 2010, 45(1), 270-274.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, Issue.1
, pp. 270-274
-
-
Zakharova, O.D.1
Ovchinnikova, L.P.2
Goryunov, L.I.3
Troshkova, N.M.4
Shteingarts, V.D.5
Nevinsky, G.A.6
-
68
-
-
78650727345
-
Cytotoxicity of new polyfluorinated 1,4-naphtoquinones with diverse substituents in the quinone moiety
-
Zakharova, O.D.; Ovchinnikova, L.P.; Goryunov, L.I.; Troshkova, N.M.; Shteingarts, V.D.; Nevinsky, G.A. Cytotoxicity of new polyfluorinated 1,4-naphtoquinones with diverse substituents in the quinone moiety. Bioorg. Med. Chem., 2011, 19(1), 256-260.
-
(2011)
Bioorg. Med. Chem.
, vol.19
, Issue.1
, pp. 256-260
-
-
Zakharova, O.D.1
Ovchinnikova, L.P.2
Goryunov, L.I.3
Troshkova, N.M.4
Shteingarts, V.D.5
Nevinsky, G.A.6
-
69
-
-
84855838940
-
CDC25 inhibitors
-
December 09
-
Nussbaum, F.; Ebbinghaus A.; Mayer-Bartschmid, A.; Zitzmann, W.; Wiese W.B.; Stadler M.; Anlauf, S. CDC25 inhibitors. E. P. Patent 2, 130, 831, December 09, 2009.
-
(2009)
E. P. Patent 2, 130, 831
-
-
Nussbaum, F.1
Ebbinghaus, A.2
Mayer-Bartschmid, A.3
Zitzmann, W.4
Wiese, W.B.5
Stadler, M.6
Anlauf, S.7
-
70
-
-
84855824130
-
Antibiotic Diazaquionomycin a derivative
-
April 09
-
Omura S.; Tanaka, H.; Tsuzuki, K.; Murata, Y. Antibiotic Diazaquionomycin a derivative. Jp. Patent, 6,307,983,0, April 09, 1988.
-
(1988)
Jp. Patent, 6,307,983,0
-
-
Omura, S.1
Tanaka, H.2
Tsuzuki, K.3
Murata, Y.4
-
71
-
-
84855824131
-
Antitumoral aza-and diazaanthracenes
-
December 15
-
Avendano, C.;. Alonso, M. A.; Espada, M.; Garcia Gravalos, D.; Antitumoral aza-and diazaanthracenes. E. P. Patent 0, 574, 195, December 15, 1993.
-
(1993)
E. P. Patent 0, 574, 195
-
-
Avendano, C.1
Alonso, M.A.2
Espada, M.3
Garcia Gravalos, D.4
-
72
-
-
84855849987
-
Anthraquinonic derivatives having an antitumor activity and applications thereof
-
February 10
-
Avendano Lopez C.; Garcia Gravalos, D. Anthraquinonic derivatives having an antitumor activity and applications thereof. U.S. Patent 5,716,963, February 10, 1998.
-
(1998)
U.S. Patent 5,716,963
-
-
Avendano Lopez, C.1
Garcia Gravalos, D.2
-
73
-
-
84855860207
-
Triaminopyrimidine derivatives as inhibitors of CDC25 phosphatase
-
March 06
-
Prevost, G.; Liberatore, A.M.; Bigg, D.; Pons, D. Triaminopyrimidine derivatives as inhibitors of CDC25 phosphatase. U.S. Patent 0, 137, 275, March 06, 2010.
-
(2010)
U.S. Patent 0, 137, 275
-
-
Prevost, G.1
Liberatore, A.M.2
Bigg, D.3
Pons, D.4
-
74
-
-
84855824133
-
Triaminopyrimidine cyclobutenedione derivatives used as phosphatase CDC25 inhibitors
-
August 07
-
Liberatore, A.M.; Pons, D.; Bigg, D.; Prevost, G.; Brezak Pannetier, M.C. Triaminopyrimidine cyclobutenedione derivatives used as phosphatase CDC25 inhibitors. U.S. Patent 0,173,910, August 07, 2010.
-
(2010)
U.S. Patent 0,173,910
-
-
Liberatore, A.M.1
Pons, D.2
Bigg, D.3
Prevost, G.4
Brezak Pannetier, M.C.5
-
75
-
-
84855824134
-
Method for obtaining human CDC25 phosphatases and method for identifying human CDC25 phosphatase modulators
-
June 21
-
Goubin-Gramatica, F.; Ducommun, B.; Prevost, G.; Method for obtaining human CDC25 phosphatases and method for identifying human CDC25 phosphatase modulators. W.O. Patent 0, 144, 467, June 21, 2001.
-
(2001)
W.O. Patent 0, 144, 467
-
-
Goubin-Gramatica, F.1
Ducommun, B.2
Prevost, G.3
-
76
-
-
84855849989
-
Triaminopyrimidine derivatives as CDC25 phosphatase inhibitors
-
November 18
-
Liberatore, A.M.; Prevost, G. Auvin, S.; Brehu, L.; Triaminopyrimidine derivatives as CDC25 phosphatase inhibitors. W.O. Patent 1, 309, 00, November 18, 2010.
-
(2010)
W.O. Patent 1, 309, 00
-
-
Liberatore, A.M.1
Prevost, G.2
Auvin, S.3
Brehu, L.4
-
77
-
-
34250834968
-
What's new on CDC25 phosphatase inhibitors
-
Contour-Galcera, M.O.; Sidhu, A.; Prévost, G.; Bigg, D.; Ducommun, B. What's new on CDC25 phosphatase inhibitors. Pharmacol. Ther., 2006, 115(1), 1-12.
-
(2006)
Pharmacol. Ther.
, vol.115
, Issue.1
, pp. 1-12
-
-
Contour-Galcera, M.O.1
Sidhu, A.2
Prévost, G.3
Bigg, D.4
Ducommun, B.5
-
78
-
-
43049129579
-
Targeting PTPs with small molecule inhibitors in cancer treatment
-
Jiang, Z.X.; Zhang, Z.Y. Targeting PTPs with small molecule inhibitors in cancer treatment. Cancer Metastasis Rev., 2008, 27(2), 263-272.
-
(2008)
Cancer Metastasis Rev.
, vol.27
, Issue.2
, pp. 263-272
-
-
Jiang, Z.X.1
Zhang, Z.Y.2
-
79
-
-
29244437883
-
Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate
-
Sohn, J.; Parks, J.M.; Buhrman, G.; Brown, P.; Kristjánsdóttir, K.; Safi A.; Edelsbrunner, H.; Yang, W.; Rudolph, J. Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate. Biochemistry, 2005, 44(50), 16563-16573.
-
(2005)
Biochemistry
, vol.44
, Issue.50
, pp. 16563-16573
-
-
Sohn, J.1
Parks, J.M.2
Buhrman, G.3
Brown, P.4
Kristjánsdóttir, K.5
Safi, A.6
Edelsbrunner, H.7
Yang, W.8
Rudolph, J.9
-
80
-
-
27844590828
-
Redox regulation of Cdc25B by cell-active quinolinediones
-
Brisson, M.; Nguyen, T.; Wipf, P.; Joo, B.; Day, B.W.; Skoko, J.S.; Schreiber, E.M.; Foster, C.; Bansal, P.; Lazo, J.S. Redox regulation of Cdc25B by cell-active quinolinediones. Mol Pharmacol., 2005, 68(6),1810-1820.
-
(2005)
Mol Pharmacol.
, vol.68
, Issue.6
, pp. 1810-1820
-
-
Brisson, M.1
Nguyen, T.2
Wipf, P.3
Joo, B.4
Day, B.W.5
Skoko, J.S.6
Schreiber, E.M.7
Foster, C.8
Bansal, P.9
Lazo, J.S.10
-
81
-
-
33845878529
-
Independent mechanistic inhibition of cdc25 phosphatases by a natural product caulibugulone
-
Brisson, M.; Foster, C.; Wipf, P.; Joo, B.; Tomko, R.J. Jr.; Nguyen, T.; Lazo, J.S. Independent mechanistic inhibition of cdc25 phosphatases by a natural product caulibugulone. Mol. Pharmacol. 2007, 71(1), 184-192.
-
(2007)
Mol. Pharmacol
, vol.71
, Issue.1
, pp. 184-192
-
-
Brisson, M.1
Foster, C.2
Wipf, P.3
Joo, B.4
Tomko Jr., R.J.5
Nguyen, T.6
Lazo, J.S.7
-
82
-
-
52749098453
-
Computational design, synthesis and biological evaluation of para-quinone based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B
-
Keinan, S.; Paquette, W.D.; Skoko, J.J.; Beratan, D.N.; Yang, W.; Shinde, S.; Johnston, P.A.; Lazo J.S.; Wipf, P. Computational design, synthesis and biological evaluation of para-quinone based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B. Org. Biomol. Chem., 2008, 6(18), 3256-3263.
-
(2008)
Org. Biomol. Chem.
, vol.6
, Issue.18
, pp. 3256-3263
-
-
Keinan, S.1
Paquette, W.D.2
Skoko, J.J.3
Beratan, D.N.4
Yang, W.5
Shinde, S.6
Johnston, P.A.7
Lazo, J.S.8
Wipf, P.9
|