Correlating computed tomography perfusion changes in the pharyngeal constrictor muscles during head-and-neck radiotherapy to dysphagia outcome

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 2, 2012, Pages

  Truong, Minh Tam ^a   Lee, Richard ^a   Saito, Naoko ^a   Qureshi, Muhammad M ^a   Ozonoff, Al ^b   Romesser, Paul B ^a   Wang, Jimmy ^a   Sakai, Osamu ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

CT perfusion imaging; Dysphagia; Functional imaging; Head and neck cancer; Intensity modulated radiotherapy; Pharyngeal constrictor muscles; Radiotherapy

Indexed keywords

CT PERFUSION IMAGING; DYSPHAGIA; FUNCTIONAL IMAGING; HEAD-AND-NECK CANCER; INTENSITY-MODULATED RADIOTHERAPY;

BLOOD; DISEASES; HEMODYNAMICS; MULTIVARIANT ANALYSIS; MUSCLE; RADIOTHERAPY; TOMOGRAPHY;

COMPUTERIZED TOMOGRAPHY;

CETUXIMAB; CISPLATIN; IOVERSOL;

ADULT; AGED; ARTICLE; BLOOD VOLUME; CANCER PATIENT; CANCER RADIOTHERAPY; CAPILLARY PERMEABILITY; CHEMORADIOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE SEVERITY; DYSPHAGIA; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HUMAN; HYPOPHARYNX CANCER; MALE; MUSCLE; MUSCLE BLOOD FLOW; MUSCLE PERFUSION; NASOPHARYNX CANCER; OROPHARYNX CANCER; OUTCOME ASSESSMENT; PHARYNGEAL CONSTRICTOR MUSCLE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; RADIATION INJURY;

AGED; BLOOD VOLUME; CHEMORADIOTHERAPY; DEGLUTITION DISORDERS; FEMALE; FOLLOW-UP STUDIES; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIVARIATE ANALYSIS; PHARYNGEAL MUSCLES; PROSPECTIVE STUDIES; RADIOTHERAPY, INTENSITY-MODULATED; REGIONAL BLOOD FLOW; SMOKING; TIME FACTORS; TUMOR BURDEN;

EID: 84855842742     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.04.058     Document Type: Article

References (25)

1. N.P. Nguyen, S. Sallah, and U. Karlsson Combined chemotherapy and radiation therapy for head and neck malignancies: Quality of life issues Cancer 94 2002 1131 1141
2. C.L. Lazarus, J.A. Logemann, and B.R. Pauloski Swallowing disorders in head and neck cancer patients treated with radiotherapy and adjuvant chemotherapy Laryngoscope 106 1996 1157 1166
3. N.P. Nguyen, C.C. Moltz, and C. Frank Dysphagia following chemoradiation for locally advanced head and neck cancer Ann Oncol 15 2004 383 388
4. F.Y. Feng, H.M. Kim, and T.H. Lyden Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: Early dose-effect relationships for the swallowing structures Int J Radiat Oncol Biol Phys 68 2007 1289 1298
5. A. Eisbruch, M. Schwartz, and C. Rasch Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: Which anatomic structures are affected and can they be spared by IMRT? Int J Radiat Oncol Biol Phys 60 2004 1425 1439
6. P.C. Levendag, D.N. Teguh, and P. Voet Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: A dose-effect relationship Radiother Oncol 85 2007 64 73
7. B.R. Pauloski Rehabilitation of dysphagia following head and neck cancer Phys Med Rehabil Clin N Am 19 2008 889 928 x
8. B.D. Kulbersh, E.L. Rosenthal, and B.M. McGrew Pretreatment, preoperative swallowing exercises may improve dysphagia quality of life Laryngoscope 116 2006 883 886
9. S.A. Bhide, S. Gulliford, and R. Kazi Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer Radiother Oncol 93 2009 539 544
10. D. Gandhi, E.G. Hoeffner, and R.C. Carlos Computed tomography perfusion of squamous cell carcinoma of the upper aerodigestive tract. Initial results J Comput Assist Tomogr 27 2003 687 693
11. R. Hermans, M. Meijerink, and W. Van den Bogaert Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy Int J Radiat Oncol Biol Phys 57 2003 1351 1356
12. Z. Rumboldt, R. Al-Okaili, and J.P. Deveikis Perfusion CT for head and neck tumors: Pilot study AJNR Am J Neuroradiol 26 2005 1178 1185
13. Truong MT, Saito N, Wang, JW, et al. Prediction of locoregional control in head and neck squamous cell carcinoma with serial CT perfusion during radiotherapy. Am J Neuroradiol. In press.
14. K.A. Miles Perfusion CT for the assessment of tumour vascularity: Which protocol? Br J Radiol 76 Spec. No 1 2003 S36 S42
15. A. Trotti, A.D. Colevas, and A. Setser CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment Semin Radiat Oncol 13 2003 176 181
16. American Joint Committee on Cancer Cancer staging manual 2002 Springer-Verlag New York
17. J.J. Caudell, P.E. Schaner, and R.A. Desmond Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck Int J Radiat Oncol Biol Phys 76 2010 403 409
18. A. Eisbruch, P.C. Levendag, and F.Y. Feng Can IMRT or brachytherapy reduce dysphagia associated with chemoradiotherapy of head and neck cancer? The Michigan and Rotterdam experiences Int J Radiat Oncol Biol Phys 69 2007 S40 S42
19. W. Zhao, D.I. Diz, and M.E. Robbins Oxidative damage pathways in relation to normal tissue injury Br J Radiol 80 Spec. No 1 2007 S23 S31
20. F. Paris, Z. Fuks, and A. Kang Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice Science 293 2001 293 297
21. K. Surlan-Popovic, S. Bisdas, and Z. Rumboldt Changes in perfusion CT of advanced squamous cell carcinoma of the head and neck treated during the course of concomitant chemoradiotherapy AJNR Am J Neuroradiol 31 2010 570 575
22. S. Bisdas, Z. Rumboldt, and K. Surlan-Popovic Perfusion CT in squamous cell carcinoma of the upper aerodigestive tract: Long-term predictive value of baseline perfusion CT measurements AJNR Am J Neuroradiol 31 2010 576 581
23. A. Popovtzer, Y. Cao, and F.Y. Feng Anatomical changes in the pharyngeal constrictors after chemo-irradiation of head and neck cancer and their dose-effect relationships: MRI-based study Radiother Oncol 93 2009 510 515
24. H.B. Caglar, R.B. Tishler, and M. Othus Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy Int J Radiat Oncol Biol Phys 72 2008 1110 1118
25. K. Dornfeld, S. Hopkins, and J. Simmons Posttreatment FDG-PET uptake in the supraglottic and glottic larynx correlates with decreased quality of life after chemoradiotherapy Int J Radiat Oncol Biol Phys 71 2008 386 392