Effects of phenytoin sodium on dura mater healing in a rat model of csf leakage

Turkish Neurosurgery

Volumn 21, Issue 4, 2011, Pages 471-476

  Ergun, Ertan ^a   Kurt, Gokhan ^a   Tonge, Mehmet ^a   Aytar, Hamit ^a   Tas, Murat ^a   Baykaner, Kemali ^a   viker, Necdet Ce ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

CSF leakage; Dura mater; Healing; Phenytoin sodium

Indexed keywords

EID: 84855832327     PISSN: 10195149     EISSN: None     Source Type: Journal    
DOI: 10.5137/1019-5149.Jtn.4165-11.2     Document Type: Article

References (24)

1. Anstead GM, Hart LM, Sunahara JF, Liter ME: Phenytoin in wound healing. Ann Pharmacother 30:768-775, 1996
2. Bansal NK, Mukul: Comparison of topical phenytoin with normal saline in the treatment of chronic trophic ulcers in leprosy. Int J Dermatol 32:210-213, 1993
3. Bhatia A, Prakash S: Topical phenytoin for wound healing. Dermatol Online J 10(1):5, 2004
4. Conn RD: Diphenylhydantoin sodium in cardiac arrhythmias. N Eng J Med 272:277-282, 1965
5. Czapinski P, Blaszczyk B, Czucwar SJ: Mechanisms of action of antiepileptic drugs. Curr Top Med Chem 5(1):3-14, 2005
6. El Zayat SG: Preliminary experience with topical phenytoin in wound healing in a war zone. Mil Med 154:178-180, 1989
7. Ettinger AB, Argoff CE: Use of antiepileptic drugs for nonepileptic conditions: Psychiatric disorders and chronic pain. Neurotherapeutics 4(1)75-83
8. Jensen TS: Anticonvulsants in neuropathic pain: Rationale and clinical evidence. European Journal of Pain 2002 6(Suppl):61-68, 2007
9. Kimball OP: The treatment of epilepsy with sodium diphenyl hydantoine. J Am Med Assoc 112(13):1244-1245, 1939
10. Lodha SC, Lohiya ML, Vyas MC, Bhandari S, Goyal RR, Harsh MK: Role of phenytoin in healing of large abscess cavities. Br J Surg 78:105-108, 1991
11. McDonald RL, Kelly KM: Antiepileptic drug mechanisms of action. Epilepsia 36 Suppl 2:S2-12, 1995
12. Merritt HH, Putnam TJ: Landmark article Sept 17, 1938: Sodium diphenyl hydantoinate in the treatment of convulsive disorders. By H. Houston Merritt and Tracy J. Putnam. JAMA 251(8):1062-1067, 1984
13. Modaghegh S, Salehian B, Tavassoli M, Djamshidi A, Rezai AS: Use of phenytoin in healing of war and non-war wounds. A pilot study of 25 cases. Int J Dermatol 28:347-350, 1989
14. Moy LS, Tan EM, Holness R, Uitto J: Phenytoin modulates connective tissue metabolism and cell proliferation in human skin fibroblast cultures. Arch Dermatol 121:79-83, 1985
15. Mulleners WM, Chronicle EP: Anticonvulsants in migraine prophylaxis: A cochrane review. Cephalalgia 28:585-597, 2008
16. Oluwatosin OM, Olabanji JK, Oluwatosin OA, Tijani LA, Onyechi HU: A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers. Afr J Med Sci 29:31-34, 2000
17. Ozisik PA, Inci S, Soylemezoglu F, Orhan H, Ozgen T: Comparative dural closure techniques: A safety study in rats. Surgical Neurology 65:42-47, 2006
18. Pendse AK, Sharma A, Sodani A, Hada S: Topical phenytoin in wound healing. Int J Dermatol 32:214-217, 1993
19. Preul MC, Bichard WD, Spetzler RF: Toward optimal tissue sealants for neurosurgery: Use of a novel hydrogel sealant in a canine durotomy repair model. Neurosurgery 53:1189-1198, 2003
20. Shafer WG: Effect of dilantin sodium analogues on cell proliferation in tissue culture. Proc Soc Exp Biol Med 106: 205-207, 1961
21. Shapiro M: Acceleration of gingival wound healing in nonepileptic patients recieving diphenylhydantoin sodium (dilantin, epanutin) Exp Med Surg 16(1):41-53, 1958
22. Sugawara T, Itoh Y, Hirano Y, Higashiyama N, Shimada Y, Kinouchi H: Novel duramater closure technique using polyglactin acid sheet prevents cerebrospinal fluid leakage after spinal surgery. Neurosurgery 57:290-294, 2005
23. Talas G, Brown RA, McGrouther DA: Role of phenytoin in wound healing-a wound pharmacology perspective. Biochem Pharmacol 57:1085-1094, 1999
24. Yadav JK, Singhvi AM, Kumar N, Garg S: Topical phenytoin in the treatment of splitt hickness skin autograft donor sites: A comparative study with polyurethane membrane drape and conventional dressing. Burns 19:306-310, 1993