Mononucleated and binucleated cardiomyocytes in left atrium and pulmonary vein have different electrical activity and calcium dynamics

Progress in Biophysics and Molecular Biology

Volumn 108, Issue 1-2, 2012, Pages 64-73

  Huang, Chun Feng ^a,b,c   Chen, Yao Chang ^e   Yeh, Hung I ^f   Chen, Shih Ann ^d  

^a Saint Mary's Hospital   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NURSING AND MANAGEMENT COLLEGE   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^f MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Atrial fibrillation; Calcium homeostasis; Electrophysiology; Nucleus number

Indexed keywords

CALCIUM;

ANIMAL; CELL MEMBRANE; CELL NUCLEUS; CYTOLOGY; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; HEART ATRIUM; HEART MUSCLE CELL; HOMEOSTASIS; MALE; METABOLISM; PULMONARY VEIN; RABBIT; REVIEW;

ANIMALS; CALCIUM; CELL MEMBRANE; CELL NUCLEUS; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGICAL PROCESSES; HEART ATRIA; HOMEOSTASIS; MALE; MYOCYTES, CARDIAC; PULMONARY VEINS; RABBITS;

EID: 84855826312     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbiomolbio.2011.09.007     Document Type: Review

References (27)

1. Ambrosino C., Nebreda A.R. Cell cycle regulation by p38 MAP kinases. Bio. Cell 2001, 93:47-51.
2. Barbera A., Giraud G.D., Reller M.D., Maylie J., Morton M.J., Thornburg K.L. Right ventricular systolic pressure load alters myocyte maturation in fetal sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 279:R1157-R1164.
3. 2+ stores potentially determine the spontaneous activity of pulmonary vein cardiomyocytes. Life Sci. 2008, 83:284-292.
4. Chen S.A., Hsieh M.H., Tai C.T., Tsai C.F., Prakash V.S., Yu W.C., Hsu T.L., Ding Y.A., Chang M.S. Initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins: electrophysiological characteristics, pharmacological responses, and effects of radiofrequency ablation. Circulation 1999, 100:1879-1886.
5. Chen Y.J., Chen S.A., Chen Y.C., Yeh H.I., Chan P., Chang M.S., Lin C.I. Effects of rapid atrial pacing on the arrhythmogenic activity of single cardiomyocytes from pulmonary veins: implication in initiation of atrial fibrillation. Circulation 2001, 104:2849-2854.
6. Chen Y.C., Chen S.A., Chen Y.J., Chang M.S., Chan P., Lin C.I. Effects of thyroid hormone on the arrhythmogenic activity of pulmonary vein cardiomyocytes. J.Am. Coll. Cardiol. 2002, 39:366-372.
7. Chen Y.J., Chen S.A., Chen Y.C., Yeh H.I., Chang M.S., Lin C.I. Electrophysiology of single cardiomyocytes isolated from rabbit pulmonary veins: implication in initiation of focal atrial fibrillation. Basic Res. Cardiol. 2002, 97:26-34.
8. Chen Y.C., Chen S.A., Chen Y.J., Tai C.T., Chan P., Lin C.I. T-type calcium current in electrical activity of cardiomyocytes isolated from rabbit pulmonary vein. J.Cardiovasc. Electrophysiol. 2004, 15:567-571.
9. Chen X., Wilson R.M., Kubo H., Berretta R.M., Harris D.M., Zhang X., Jaleel N., MacDonnell S.M., Bearzi C., Tillmanns J., Trofimova I., Hosoda T., Mosna F., Cribbs L., Leri A., Kajstura J., Anversa P., Houser S.R. Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties. Circ. Res. 2007, 100:536-544.
10. Chen Y.J., Chen Y.C., Wongcharoen W., Lin C.I., Chen S.A. Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes. Br. J. Pharmacol. 2008, 153:915-925.
11. Chen Y.C., Kao Y.H., Huang C.F., Cheng C.C., Chen Y.J., Chen S.A. Heat stress responses modulate calcium regulations and electrophysiological characteristics in atrial myocytes. J.Mol. Cell Cardiol. 2010, 48:781-788.
12. Chou C., Nihei M., Zhou S., Tan A., Kawase A., Macias E.S., Fishbein M.C., Lin S.F., Chen P.S. Intracellular calcium dynamics and anisotropic reentry in isolated canine pulmonary veins and left atrium. Circulation 2005, 111:2889-2897.
13. Fujiki A., Yoshida S., Sasayama S. Paroxysmal atrial fibrillation with and without primary atrial vulnerability. J.Electrocardiol. 1989, 22:153-157.
14. Grajek S., Lesiak M., Pyda M., Zajac M., Paradowski S.T. Hypertrophy or hyperplasia in cardiac muscle. Post-mortem human morphometric study. Eur. Heart J. 1993, 14:40-47.
15. Haissaguerre M., Jais P., Shah D.C., Gencel L., Pradeau V., Gappigues S., Chouairi S., Hocini M., Metayer P.L.E., Roudaut R., Clementy J. Right and left atrial radiofrequency catheter ablation therapy of paroxysmal atrial fibrillation. J.Cardiovasc. Electrophysiol. 1996, 7:1132-1144.
16. Haissaguerre M., Jais P., Shah D.C., Takahashi A., Hocini M., Quiniou G., Garrigue S., Mouroux A.L., Metayer P.L., Clementy J. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N.Engl. J. Med. 1998, 339:659-666.
17. Ter Keurs H.E., Boyden P.A. Calcium and arrhythmogenesis. Physiol. Rev. 2007, 87:457-506.
18. Liang Q., Molkentin J.D. Redefing the roles of p38 and JNK signaling in cardiac hypertrophy. dichotomy between cultured myocytes and animal models. J.Mol. Cell Cardiol. 2003, 35:1385-1394.
19. Liu J., Bi H., Zhu M.Z., Zheng Q.S., Lu S.P. Effects of short-term atrial fibrillation on effective refractory period and L-type calcium current of rabbit pulmonary vein cardiomyocytes. Chin. Heart J. 2007, 19:25-27.
20. Melnyk P., Ehrlich J.R., Pourrier M., Villeneuve L., Cha T.J., Nattel S. Comparison of ion channel distribution and expression in cardiomyocytes of canine pulmonary veins versus left atrium. Cardiovasc. Res. 2005, 65:104-116.
21. Michelucci A., Padeletti L., Fradella G.A. Atrial refractoriness and spontaneous or induced atrial fibrillation. Acta Cardiol. 1982, 37:333-344.
22. Pogwizd S.M., Schlotthauer K., Li L., Yuan W., Bers D.M. Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ. Res. 2001, 88:1159-1167.
23. Rota M., Hosoda T., De Angelis A., Arcarese M.L., Esposito G., Rizzi R., Tillmanns J., Tugal D., Musso E., Rimoldi O., Bearzi C., Urbanek K., Anversa P., Leri A., Kajstura J. The young mouse heart is composed of myocytes heterogeneous in age and function. Circ. Res. 2007, 17(101):387-399.
24. Sundgren N.C., Giraud G.D., Stork P.J.S., Maylie J.G., Thornburg K.L. Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes. J.Physiol. 2003, 548:881-891.
25. Suzuki G., Lee T.C., Fallavollita J.A., Canty J.M. Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle. Circ. Res. 2005, 96:767-775.
26. Walden A.P., Dibb K.M., Trafford A.W. Differences in intracellular calcium homeostasis between atrial and ventricular myocytes. J.Mol. Cell Cardiol. 2009, 46:463-473.
27. Yeh H.I., Lai Y.J., Lee S.H., Lee Y.N., Ko Y.S., Chen S.A., Severs N.J., Tsai C.H. Heterogeneity of myocardial sleeve morphology and gap junctions in canine superior vena cava. Circulation 2001, 104:3152-3157.