IL28B polymorphism, explanation for different responses to therapy in hepatitis C patients

Hepatitis Monthly

Volumn 11, Issue 12, 2011, Pages 958-959

  Sharafi, Heidar ^a   Alavian, Seyed Moayed ^b  

^a Armin Pathobiology Laboratory   (Iran)

^b BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Genetic hepatitis C; Human; IL28B protein; Polymorphism

Indexed keywords

INSULIN; PEGINTERFERON; RIBAVIRIN; VIRUS RNA;

AGE DISTRIBUTION; BODY MASS; DISEASE ASSOCIATION; DRUG RESPONSE; EDITORIAL; ETHNIC DIFFERENCE; FIBROSIS; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEPATITIS C; HUMAN; IL28B GENE; INSULIN RESISTANCE; MIXED INFECTION; NONHUMAN; PREDICTION; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 84855817536     PISSN: 1735143X     EISSN: 17353408     Source Type: Journal    
DOI: 10.5812/kowsar.1735143X.794     Document Type: Editorial

References (17)

1. Alavian SM. New globally faces of hepatitis B and C in the world. Gastro Hepat FBB. 2011;4(4):171-4.
2. Alavian SM, Tabatabaei SV, Keshvari M, Behnava B, Miri SM, Elizee pK, et al. peginterferon alpha-2a and ribavirin treatment of pa- tients with haemophilia and hepatitis C virus infection: a single- centre study of 367 cases. Liver Int. 2010;30(8):1173-80.
3. Alavian SM. Are the Real HCV Infection Features in Iranian patients the Same As What Is expected? Hepat Mon. 2005;5(1):3-5.
4. Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, et al. Genetic variation in IL28B predicts hepatitis C treatment- induced viral clearance. Nature. 2009;461(7262):399-401.
5. Suppiah V, Moldovan M, Ahlenstiel G, Berg T, Weltman M, Abate ML, et al. IL28B is associated with response to chronic hepati- tis C interferon-alpha and ribavirin therapy. Nature Genetics. 2009;41(10):1100-4.
6. Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nature Genetics. 2009;41(10):1105-9.
7. Rauch A, Kutalik Z, Descombes P, Cai T, Di Iulio J, Mueller T, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastro- enterology. 2010;138(4):1338-45.
8. Li S, Hu P, Zhang QQ, Liu YH, Hu HD, Zhang DZ, et al. Single nucleotide polymorphisms of the IL28B and sustained virologic response of patients with chronic hepatitis C to peG-interferon/ ribavirin therapy: A meta-analysis: Meta-analysis of IL28B. Hepat Mon. 2011;11(3):163-72.
9. Asselah T, De Muynck S, Broet P, Masliah-planchon J, Blanluet M, Bieche I, et al. IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C. J Hepatol. 2011:[Epub ahead of print].
10. De nicola S, Aghemo A, Rumi MG, Galmozzi E, Valenti L, Soffredini R, et al. An IL28B polymorphism predicts pegylated interferon plus ribavirin treatment outcome in chronic hepatitis c geno-type 4. Hepatology. 2011:[Epub ahead of print].
11. Mangia A, Thompson AJ, Santoro R, piazzolla V, Tillmann HL, patel K, et al. An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology. 2010;139(3):821-7.
12. Moghaddam A, Melum E, Reinton N, Ring-Larsen H, Verbaan H, Bjoro K, et al. IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection. Hepatology. 2011;53(3):746-54.
13. Sarrazin C, Susser S, Doehring A, Lange CM, Muller T, Schlecker C, et al. Importance of IL28B gene polymorphisms in hepatitis C vi- rus genotype 2 and 3 infected patients. J Hepatol. 2011;54(3):415-21.
14. European Association for the Study of the L. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol. 2011;55(2):245-64.
15. Ghany MG, Nelson DR, Strader DB, Thomas DL, Seeff LB, American Association for Study of Liver D. An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology. 2011;54(4):1433-44.
16. Sporea I, popescu A, Curescu M, Sirli R, Dan I, Goldi A, et al. The Correlation of Il28B Genotype With Sustained Virologic Response In Romanian patients With Chronic Hepatitis C. Hepat Mon. 2011;11(12):956-7.
17. Yonan AL, palmer AA, Gilliam TC. Hardy-Weinberg disequilibrium identified genotyping error of the serotonin transporter (SL- C6A4) promoter polymorphism. Psychiatr Genet. 2006;16(1):31-4.