Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model

Journal of Controlled Release

Volumn 157, Issue 2, 2012, Pages 235-242

  Bazan Peregrino, Miriam ^a   Arvanitis, Costas D ^a   Rifai, Bassel ^a   Seymour, Leonard W ^a   Coussios, Constantin C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Breast cancer; Cavitation; HIFU; Oncolytic adenovirus; Ultrasound; Virotherapy

Indexed keywords

ACOUSTIC ENERGY; BREAST CANCER; BROADBAND EMISSION; CANCER CELLS; CELL VIABILITY; DUTY CYCLES; EXPOSURE CONDITIONS; FLUID CHANNELS; FOCAL VOLUME; GEL MATRIX; HIFU; HUMAN BREAST CANCER CELLS; IN-VITRO; INERTIAL CAVITATION; MATRIX; MECHANISM OF ACTION; MICROBUBBLES; ONCOLYTIC ADENOVIRUS; RECEPTOR CELLS; SONOPORATION; STABLE CAVITATION; THERAPEUTIC EFFICACY; TRANSGENE EXPRESSION; TUMOUR CELLS; ULTRASONIC PRESSURE; ULTRASOUND BEAMS; ULTRASOUND-INDUCED CAVITATION; VIROTHERAPY;

BLOOD; BLOOD VESSELS; CELLS; DISEASES; GELS; TUMORS; ULTRASONICS; VIRUSES;

CAVITATION;

LUCIFERASE; ONCOLYTIC ADENOVIRUS;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CANCER MODEL; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; EXTRAVASATION; GENE EXPRESSION REGULATION; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROBUBBLE; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PRIORITY JOURNAL; TRANSGENE; TUMOR VASCULARIZATION; ULTRASOUND; ULTRASOUND INDUCED CAVITATION;

ACOUSTICS; ADENOVIRIDAE; ANIMALS; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; HUMANS; MICE;

EID: 84855811617     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.09.086     Document Type: Article

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