Teaching an old scaffold new tricks: Monobodies constructed using alternative surfaces of the FN3 scaffold

Journal of Molecular Biology

Volumn 415, Issue 2, 2012, Pages 393-405

  Koide, Akiko ^a   Wojcik, John ^a   Gilbreth, Ryan N ^a   Hoey, Robert J ^a   Koide, Shohei ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

antibody mimic; combinatorial library; phage display; protein design; protein protein interaction

Indexed keywords

AMINO ACID; ANTIBODY; BINDING PROTEIN; FIBRONECTIN; FIBRONECTIN TYPE 3; IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; COMBINATORIAL LIBRARY; COMPLEX FORMATION; CRYSTAL STRUCTURE; MOLECULAR LIBRARY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SURFACE PROPERTY;

EID: 84855802142     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.12.019     Document Type: Article

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