Cyclolobatriene, a novel prenylated germacrene diterpene, from the soft coral Lobophytum pauciflorum

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 2, 2012, Pages 687-692

  Govindam, Sudhakar V S ^a   Yoshioka, Yukio ^b   Kanamoto, Akihiko ^c   Fujiwara, Takeshi ^c   Okamoto, Tetsuji ^b   Ojika, Makoto ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c OP Bio Factory Co Ltd   (Japan)

Author keywords

Cyclolobatriene; Cytotoxic; Germacrene; Lobane diterpene; Lobophytum; Soft coral

Indexed keywords

2,3 DIHYDROCYCLOLOBATRIENE; 6,7 DIHYDROCYCLOLOBATRIENE; CYCLOLOBATRIENE; CYTOTOXIC AGENT; DITERPENE; EUNICOL; FUSCOL; GERMACRENE DERIVATIVE; LOBATRIENE; LOBOPHYTUM PAUCIFLORUM EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; CORAL; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STABILITY; DRUG STRUCTURE; HEATING; HUMAN; HUMAN CELL; IC 50; LOBOPHYTUM PAUCIFLORUM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSICAL CHEMISTRY; PRENYLATION; SQUAMOUS CELL CARCINOMA; THERMOSTABILITY;

ANIMALS; ANTHOZOA; CELL LINE, TUMOR; DITERPENES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION;

ALCYONACEA; LOBOPHYTUM; LOBOPHYTUM PAUCIFLORUM;

EID: 84855788959     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.12.012     Document Type: Article

References (26)

1. J.-M. Kornprobst Encyclopedia of Marine Natural Products Vol. 2 2010 Wiley-Blackwell Weinheim
2. R.W. Dunlop, and R.J. Wells Aust. J. Chem. 32 1979 1345
3. Y. Gopichand, and F.J. Schmitz Tetrahedron Lett. 39 1978 3641
4. J. Shin, and W. Fenical J. Org. Chem. 56 1991 3153
5. R.A. Edrada, P. Proksch, V. Wray, L. Witte, and L. van Ofwegen J. Nat. Prod. 61 1998 358
6. I. Bonnard, S.B. Jhaumeer-Laulloo, N. Bontemps, B. Banaigs, and M. Aknin Mar. Drugs 8 2010 359
7. C.B. Rao, S.M.D. Kumar, G. Trimurtulu, and D.V. Rao Indian J. Chem. 29B 1990 681
8. T. Hamada, T. Kusumi, M.O. Ishitsuka, and H. Kakisawa Chem. Lett. 1992 33
9. T. Kusumi, T. Hamada, M.O. Ishitsuka, I. Ohtani, and H. Kakisawa J. Org. Chem. 57 1992 1033
10. D.J. Faulkner Tetrahedron 33 1977 1421
11. J.C. Coll, B.F. Bowden, G.M. Konig, R. Braslau, and I.R. Price Bull. Soc. Chim. Belg. 95 1986 815
12. M.B. Saleh, and R.G. Kerr Aust. J. Chem. 63 2010 901
13. R.V.H. Jones, and M.D. Sutherland Aust. J. Chem. 21 1968 2255
14. K. Nishimura, N. Shinoda, and Y. Hirose Tetrahedron Lett. 10 1969 3097
15. A.J. Weinheimer, W.W. Youngblood, P.H. Washecheck, T.K.B. Karns, and L.S. Ciereszko Tetrahedron Lett. 11 1970 497
16. S.M. Colby, J. Crock, B. Dowdle-Rizzo, P.G. Lemaux, and R. Croteau Proc. Natl. Acad. Sci. U.S.A. 95 1998 2216
17. A.M. Adio Tetrahedron 65 2009 1533
18. E. Osawa, K. Shimada, M. Kodama, and S. Ito Tetrahedron Lett. 20 1979 2353
19. Y. Terada, and S. Yamamura Bull. Chem. Soc. Jpn. 55 1982 2495
20. D.M. Pawar, and E.A. Noe J. Am. Chem. Soc. 118 1996 12821
21. K. Tori, I. Horibe, H. Minato, and K. Takeda Tetrahedron Lett. 12 1971 4355
22. J.K. Sutherland Tetrahedron 30 1974 1651
23. J.A. Faraldos, S. Wu, J. Chappell, and R.M. Coates Tetrahedron 63 2007 7733
24. P.S. Wharton, Y.-C. Poon, and H.C. Kluender J. Org. Chem. 38 1973 735
25. J.-W. De Kraker, M.C.R. Franssen, A. De Groot, W.A. Konig, and H.J. Bouwmeester Plant Physiol. 117 1998 1381
26. K. Onodera, T. Fukatsu, N. Kawai, Y. Yoshioka, T. Okamoto, H. Nakamura, and M. Ojika Biosci. Biotechnol. Biochem. 68 2004 848