Polymorphism of apolipoprotein E gene and the risk of multiple sclerosis

Journal of Research in Medical Sciences

Volumn 16, Issue 12, 2011, Pages 1519-1524

  Sadeghi, Hamid Mirmohammad ^a   Sabzghabaee, Ali Mohammad ^a   Mousavian, Zeinab ^a   Saadatnia, Mohammad ^b   Shirani, Shahin ^b   Moazen, Fatemeh ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Allele; Apolipoprotein E; Gene; Multiple sclerosis; Polymorphism

Indexed keywords

ADULT; APOLIPOPROTEIN E GENE; ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; DNA EXTRACTION; EXPANDED DISABILITY STATUS SCALE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SCREENING; GENOTYPE; HUMAN; IRAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; MUTATOR GENE; ONSET AGE; POLYMERASE CHAIN REACTION; SEX DIFFERENCE;

EID: 84855783478     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Penkowa M, Hidalgo J. Treatment with metallothionein prevents demyelination and axonal damage and increases oligodendrocyte precursors and tissue repair during experimental autoimmune encephalomyelitis. J Neurosci Res 2003; 72(5): 574-86.
2. Oksenberg JR, Barcellos LF. Multiple sclerosis genetics: leaving no stone unturned. Genes Immun 2005; 6(5): 375-87.
3. Dyment DA, Ebers GC, Sadovnick AD. Genetics of multiple sclerosis. Lancet Neurol 2004; 3(2): 104-10.
4. Mustafina OE, Bakhtiiarova KZ, Mikhailova AM, Tuktarova IA, Khusainova AN, Nasibullin TR, et al. Analysis of the association of allelic variants of apolypoprotein E and interleukin 1 beta genes with multiple sclerosis in ethnic Tatars. Genetika 2008; 44(3): 407-13.
5. Kurtzke JF. Multiple sclerosis in time and space--geographic clues to cause. J Neurovirol 2000; 6(Suppl 2): S134-S140.
6. Burwick RM, Ramsay PP, Haines JL, Hauser SL, Oksenberg JR, Pericak-Vance MA, et al. APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology 2006; 66(9): 1373-83.
7. Hogh P, Oturai A, Schreiber K, Blinkenberg M, Jorgensen OS, Ryder L, et al. Apoliprotein E and multiple sclerosis: impact of the epsilon-4 allele on susceptibility, clinical type and progression rate. Mult Scler 2000; 6(4): 226-30.
8. Ballerini C, Campani D, Rombola G, Gran B, Nacmias B, Amato MP, et al. Association of apolipoprotein E polymorphism to clinical heterogeneity of multiple sclerosis. Neurosci Lett 2000; 296(2-3): 174-6.
9. Chapman J, Vinokurov S, Achiron A, Karussis DM, Mitosek-Szewczyk K, Birnbaum M, et al. APOE genotype is a major predictor of long-term progression of disability in MS. Neurology 2001; 56(3): 312-6.
10. Parmenter BA, Denney DR, Lynch SG, Middleton LS, Harlan LM. Cognitive impairment in patients with multiple sclerosis: association with the APOE gene and promoter polymorphisms. Mult Scler 2007; 13(1): 25-32.
11. Zong Y, Liu Z, Bi H, Yao Y, Guo J, Qu S. Cloning and expression of apolipoprotein E3 and its variant apoE2 and apoE4. J Huazhong Univ Sci Technolog Med Sci 2006; 26(1): 1-3
12. Rall SC, Jr., Weisgraber KH, Mahley RW. Human apolipoprotein E. The complete amino acid sequence. J Biol Chem 1982; 257(8): 4171-8.
13. Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988; 240(4852): 622-30.
14. Pirttila T, Haanpaa M, Mehta PD, Lehtimaki T. Apolipoprotein E (APOE) phenotype and APOE concentrations in multiple sclerosis and acute herpes zoster. Acta Neurol Scand 2000; 102(2): 94-8.
15. Mustafina OE, Mikhailova AM, Bakhtiiarova KZ, Nasibulin TR, Tuktarova IA, Makarycheva OI, et al. Polymorphism of APOE gene and risk of development of the multiple sclerosis at ethnic Russians. Mol Biol (Mosk) 2008; 42(6): 957-64.
16. Michikawa M, Fan QW, Isobe I, Yanagisawa K. Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 2000; 74(3): 1008-16.
17. Masterman T, Zhang Z, Hellgren D, Salter H, Anvret M, Lilius L, et al. APOE genotypes and disease severity in multiple sclerosis. Mult Scler 2002; 8(2): 98-103.
18. Enzinger C, Ropele S, Strasser-Fuchs S, Kapeller P, Schmidt H, Poltrum B, et al. Lower levels of N-acetylaspartate in multiple sclerosis patients with the apolipoprotein E epsilon4 allele. Arch Neurol 2003; 60(1): 65-70.
19. Schmidt S, Barcellos LF, DeSombre K, Rimmler JB, Lincoln RR, Bucher P, et al. Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. Am J Hum Genet 2002; 70(3): 708-17.
20. Stone DJ, Rozovsky I, Morgan TE, Anderson CP, Finch CE. Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease. J Neurosci 1998; 18(9): 3180-5.
21. Oh MJ, Chung EK, Shin YM, Lee KO, Park YS. The apolipoprotein E genotyping using the PCR-RFLP was useful to linkage analysis of Alzheimer's disease families. Exp Mol Med 1997; 29(3): 161-4.
22. Zhang Z, Yang X, Meng L, Liu F, Shen C, Yang W. Enhanced amplification of GC-rich DNA with two organic reagents. Biotechniques 2009; 47(3): 775-9.
23. Rall SC, Jr., Weisgraber KH, Innerarity TL, Mahley RW. Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects. Proc Natl Acad Sci U S A 1982; 79(15): 4696-700.
24. Utermann G, Langenbeck U, Beisiegel U, Weber W. Genetics of the apolipoprotein E system in man. Am J Hum Genet 1980; 32(3): 339-47.