A case of acute valproic acid poisoning treated successfully with L-carnitine

European Journal of Emergency Medicine

Volumn 19, Issue 1, 2012, Pages 57-58

  Papaseit, Esther ^a   Farré, Magí ^a   López, Maria Jesus ^a   Clemente, Carlos ^a   Campodarve, Isabel ^a  

^a HOSPITAL DEL MAR   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; AMMONIA; CARNITINE; GLUCOSE; VALPROIC ACID;

ADULT; AMMONIA BLOOD LEVEL; CASE REPORT; CONFUSION; DISORIENTATION; DRUG BLOOD LEVEL; DRUG INTOXICATION; DRUG MEGADOSE; FLUID THERAPY; FOCAL EPILEPSY; GLUCOSE BLOOD LEVEL; HUMAN; HYPERSOMNIA; LETHARGY; LETTER; MALE; OXYGEN SUPPLY; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SINGLE DRUG DOSE; SUSTAINED RELEASE PREPARATION;

ACUTE DISEASE; ADULT; ANTICONVULSANTS; CARNITINE; EPILEPSIES, PARTIAL; HUMANS; MALE; VALPROIC ACID; VITAMIN B COMPLEX;

EID: 84855782224     PISSN: 09699546     EISSN: 14735695     Source Type: Journal    
DOI: 10.1097/MEJ.0b013e328345d67e     Document Type: Letter

References (5)

1. Verrotti A, Trotta D, Morgese G, Chiarelli F. Valproate-induced hyperammonemic encephalopathy. Metab Brain Dis 2002; 17:367-373. (Pubitemid 36204766)
2. Coulter DL. Carnitine, valproate, and toxicity. J Child Neurol 1991; 6:7-14.
3. Lheureux PE, Hantson P. Carnitine in the treatment of valproic acid-induced toxicity. Clin Toxicol (Phila) 2009; 47:101-111.
4. Wadzinski J, Franks R, Roane D, Bayard M. Valproate-associated hyperammonemic encephalopathy. J Am Board Fam Med 2007; 20:499-502. (Pubitemid 350096953)
5. Chan YC, Tse ML, Lau FL. Two cases of valproic acid poisoning treated with L-carnitine. Hum Exp Toxicol 2007; 26:967-969. (Pubitemid 351650815)