-
1
-
-
79251504260
-
Current practices of process validation for drug substances and intermediates
-
Anderson N.G., Burdick D.C., Reeve M.M. Current practices of process validation for drug substances and intermediates. Org. Process Res. Dev. 2011, 15:162-172.
-
(2011)
Org. Process Res. Dev.
, vol.15
, pp. 162-172
-
-
Anderson, N.G.1
Burdick, D.C.2
Reeve, M.M.3
-
2
-
-
49149122787
-
Alternative to the microreactor
-
Ashe R. Alternative to the microreactor. Process Eng. 2008, 89:17-18.
-
(2008)
Process Eng.
, vol.89
, pp. 17-18
-
-
Ashe, R.1
-
3
-
-
84856587948
-
-
BASF Corporation, Tetrahydrofuran (THF) Storage and Handling. Material Safety Data Sheet. (retrieved 03/03/2010).
-
BASF Corporation, 1998. Tetrahydrofuran (THF) Storage and Handling. Material Safety Data Sheet. (retrieved 03/03/2010). http://www2.basf.us/diols/pdfs/thf_brochure.pdf.
-
(1998)
-
-
-
4
-
-
84856573146
-
Go with the flow
-
Boswell C. Go with the flow. ICIS Chem. Bus. Am. 2007, 271:26-27.
-
(2007)
ICIS Chem. Bus. Am.
, vol.271
, pp. 26-27
-
-
Boswell, C.1
-
7
-
-
63249085787
-
Quantifying experience in powder processing
-
Freeman T. Quantifying experience in powder processing. Pharm. Technol. Eur. 2009, 21:16-21.
-
(2009)
Pharm. Technol. Eur.
, vol.21
, pp. 16-21
-
-
Freeman, T.1
-
8
-
-
33749845639
-
Process development and production concepts for the manufacturing of organic fine chemicals at LONZA
-
Heckmann G., Previdoli F., Reidel T., Ruppen D., Veghini D., Zacher U. Process development and production concepts for the manufacturing of organic fine chemicals at LONZA. Chimia 2006, 60:530-533.
-
(2006)
Chimia
, vol.60
, pp. 530-533
-
-
Heckmann, G.1
Previdoli, F.2
Reidel, T.3
Ruppen, D.4
Veghini, D.5
Zacher, U.6
-
9
-
-
3042682174
-
Selectivity gains and energy savings for the industrial phenyl boronic acid process using micromixer/tubular reactors
-
Hessel V., Hofmann C., Löwe H., Meudt A., Scherer S., Schönfeld F., Werner B. Selectivity gains and energy savings for the industrial phenyl boronic acid process using micromixer/tubular reactors. Org. Process Res. Dev. 2004, 8:511-523.
-
(2004)
Org. Process Res. Dev.
, vol.8
, pp. 511-523
-
-
Hessel, V.1
Hofmann, C.2
Löwe, H.3
Meudt, A.4
Scherer, S.5
Schönfeld, F.6
Werner, B.7
-
10
-
-
79960496475
-
Key green engineering research areas for sustainable manufacturing: a perspective from pharmaceutical and fine chemicals manufacturers
-
Jimenéz-González C., Poechlauer P., Broxterman Q.B., Yang B., Ende D., Baird J., Bertsch C., Hannah.R.E., Dell'Orco P., Noorman H., Yee S., Reintjens R., Wells A., Massonneau V., Manley J. Key green engineering research areas for sustainable manufacturing: a perspective from pharmaceutical and fine chemicals manufacturers. Org. Process Res. Dev. 2011, 15:900-911.
-
(2011)
Org. Process Res. Dev.
, vol.15
, pp. 900-911
-
-
Jimenéz-González, C.1
Poechlauer, P.2
Broxterman, Q.B.3
Yang, B.4
Ende, D.5
Baird, J.6
Bertsch, C.7
Hannah, R.E.8
Dell'Orco, P.9
Noorman, H.10
Yee, S.11
Reintjens, R.12
Wells, A.13
Massonneau, V.14
Manley, J.15
-
11
-
-
84856584109
-
Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien.
-
Merck Patent G.m.b.H., Germany DE 10001317.
-
Koop, U., Krummradt, H., Schwarz, M., Stoldt, J., Eckstein, J., Zehner, S., 2001. Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien. Merck Patent G.m.b.H., Germany DE 10001317.
-
(2001)
-
-
Koop, U.1
Krummradt, H.2
Schwarz, M.3
Stoldt, J.4
Eckstein, J.5
Zehner, S.6
-
12
-
-
84856587951
-
Think small
-
Kossik J. Think small. Pharm. Manuf. 2002, 1:34-37.
-
(2002)
Pharm. Manuf.
, vol.1
, pp. 34-37
-
-
Kossik, J.1
-
13
-
-
33745266376
-
The microreactor a systematic and efficient tool for the transition from batch to continuous process?
-
Lomel S., Falk L., Commenge J.M., Houzelot J.L., Ramdani K. The microreactor a systematic and efficient tool for the transition from batch to continuous process?. Chem. Eng. Res. Des. 2006, 84:363-369.
-
(2006)
Chem. Eng. Res. Des.
, vol.84
, pp. 363-369
-
-
Lomel, S.1
Falk, L.2
Commenge, J.M.3
Houzelot, J.L.4
Ramdani, K.5
-
14
-
-
84856576962
-
-
(Food and Drug Administration), 2010. In: Proceedings of the ISPE Nordic Affiliate Conference on Continuous Manufacturing and PAT, Copenhagen, Handouts, 2 August
-
Moore, C. (Food and Drug Administration), 2010. In: Proceedings of the ISPE Nordic Affiliate Conference on Continuous Manufacturing and PAT, Copenhagen, Handouts, 2 August 2010.
-
(2010)
-
-
Moore, C.1
-
15
-
-
79551706348
-
Continuous oscillatory baffled reactor technology
-
Ni X. Continuous oscillatory baffled reactor technology. Innovations Pharm. Technol. 2006, 20:90-96.
-
(2006)
Innovations Pharm. Technol.
, vol.20
, pp. 90-96
-
-
Ni, X.1
-
16
-
-
84856584108
-
Novel Reactor Design for Organic-chemical Production of Pharmaceuticals.
-
M.Sc. Thesis. Department of Chemical and Biochemical Engineering, Technical University of Denmark.
-
Pedersen, M., 2009. Novel Reactor Design for Organic-chemical Production of Pharmaceuticals. M.Sc. Thesis. Department of Chemical and Biochemical Engineering, Technical University of Denmark.
-
(2009)
-
-
Pedersen, M.1
-
17
-
-
22744441634
-
Continuous processing in the pharmaceutical industry: changing the mind set
-
Plumb K. Continuous processing in the pharmaceutical industry: changing the mind set. Chem. Eng. Res. Des. 2005, 83:730-738.
-
(2005)
Chem. Eng. Res. Des.
, vol.83
, pp. 730-738
-
-
Plumb, K.1
-
19
-
-
77949915742
-
Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions
-
Riva E., Gagliardi S., Martinelli M., Passarella D., Vigo D., Rencurosi A. Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions. Tetrahedron 2010, 66:3242-3247.
-
(2010)
Tetrahedron
, vol.66
, pp. 3242-3247
-
-
Riva, E.1
Gagliardi, S.2
Martinelli, M.3
Passarella, D.4
Vigo, D.5
Rencurosi, A.6
-
20
-
-
15944366532
-
Microreactor technology: a revolution for the fine chemical and pharmaceutical industries?
-
Roberge D.M., Ducry L., Bieler N., Cretton P., Zimmermann B. Microreactor technology: a revolution for the fine chemical and pharmaceutical industries?. Chem. Eng. Technol. 2005, 28:318-323.
-
(2005)
Chem. Eng. Technol.
, vol.28
, pp. 318-323
-
-
Roberge, D.M.1
Ducry, L.2
Bieler, N.3
Cretton, P.4
Zimmermann, B.5
-
21
-
-
58149114898
-
Microreactor technology and continuous processes in the fine chemical and pharmaceutical industry: is the revolution underway?
-
Roberge D.M., Zimmermann B., Rainone F., Gottsponer M., Eyholzer M., Kockmann N. Microreactor technology and continuous processes in the fine chemical and pharmaceutical industry: is the revolution underway?. Org. Process Res. Dev. 2008, 12:905-910.
-
(2008)
Org. Process Res. Dev.
, vol.12
, pp. 905-910
-
-
Roberge, D.M.1
Zimmermann, B.2
Rainone, F.3
Gottsponer, M.4
Eyholzer, M.5
Kockmann, N.6
-
22
-
-
80052348570
-
Economic analysis of integrated continuous and batch pharmaceutical manufacturing: a case study
-
Schaber S.D., Gerogiorgis D.I., Ramachandran R., Evans J.M.B., Barton P.I., Trout B.L. Economic analysis of integrated continuous and batch pharmaceutical manufacturing: a case study. Ind. Eng. Chem. Res. 2011, 50:10083-10092.
-
(2011)
Ind. Eng. Chem. Res.
, vol.50
, pp. 10083-10092
-
-
Schaber, S.D.1
Gerogiorgis, D.I.2
Ramachandran, R.3
Evans, J.M.B.4
Barton, P.I.5
Trout, B.L.6
-
24
-
-
84856581950
-
Norvatis, MIT pair to improve drugmaking
-
(1 p.)
-
Swichtenberg B. Norvatis, MIT pair to improve drugmaking. Pharm. Manuf. 2007, 6:11. (1 p.).
-
(2007)
Pharm. Manuf.
, vol.6
, pp. 11
-
-
Swichtenberg, B.1
-
25
-
-
72449200368
-
Moving beyond the batch
-
Swichtenberg B. Moving beyond the batch. Pharm. Manuf. 2008, 7:24-26.
-
(2008)
Pharm. Manuf.
, vol.7
, pp. 24-26
-
-
Swichtenberg, B.1
-
26
-
-
84856587950
-
The reality of small scale continuous processes.
-
In: Proceedings of the Switching from Batch to Continuous Processing Conference. IChemE, London, 22-23 November 2004
-
Thomas, H., 2004. The reality of small scale continuous processes. In: Proceedings of the Switching from Batch to Continuous Processing Conference. IChemE, London, 22-23 November 2004.
-
(2004)
-
-
Thomas, H.1
-
27
-
-
33745210137
-
Evolving concepts in OSF plant design: part 2
-
Vu J., Lhoest W. Evolving concepts in OSF plant design: part 2. Pharm. Technol. Eur. 2006, 18:1-7.
-
(2006)
Pharm. Technol. Eur.
, vol.18
, pp. 1-7
-
-
Vu, J.1
Lhoest, W.2
-
28
-
-
0037704669
-
Continuous flow reactors for drug discovery
-
Watts P., Haswell S.J. Continuous flow reactors for drug discovery. Drug Discovery Today 2003, 8:586-593.
-
(2003)
Drug Discovery Today
, vol.8
, pp. 586-593
-
-
Watts, P.1
Haswell, S.J.2
-
29
-
-
53749090735
-
Continuous flow reactors, a tool for the modern synthetic chemist
-
Wiles C., Watts P. Continuous flow reactors, a tool for the modern synthetic chemist. Eur. J. Org. Chem. 2008, 2008:1655-1671.
-
(2008)
Eur. J. Org. Chem.
, vol.2008
, pp. 1655-1671
-
-
Wiles, C.1
Watts, P.2
|