Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro

Connective Tissue Research

Volumn 53, Issue 1, 2012, Pages 14-20

  Yamanouchi, Kaori ^a   Tsuruga, Eichi ^a   Oka, Kyoko ^a   Sawa, Yoshihiko ^a   Ishikawa, Hiroyuki ^a  

^a FUKUOKA DENTAL COLLEGE   (Japan)

Author keywords

ciliary zonule; fibrillin; microfibrils; oxytalan fibers

Indexed keywords

FIBRILLIN 1; FIBRILLIN 2; SMALL INTERFERING RNA;

ARTICLE; CILIARY BODY EPITHELIUM; CONNECTIVE TISSUE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OXYTALAN FIBER; WESTERN BLOTTING;

CELLS, CULTURED; CILIARY BODY; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICROFILAMENT PROTEINS; PIGMENTATION; RNA, SMALL INTERFERING;

EID: 84855772299     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008207.2011.602767     Document Type: Article

References (30)

1. Mecham, R., and Davis, E. (1994). Extracellular matrix assembly and structure. In Elastic Fiber Structure and Assembly, P. Yurchenco, D. Birk, and R. Mecham (eds.) pp. 281-314. New York: Academic Press.
2. Kielty, C.M. (2006). Elastic fibres in health and disease. Expert. Rev. Mol. Med. 8:1-23. (Pubitemid 44203758)
3. Lin, G., Tiedemann, K., Vollbrandt, T., Peters, H., Batge, B., Brinckmann, J., and Reinhardt, D.P. (2002). Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils. J. Biol. Chem. 277:50795-50804. (Pubitemid 36042244)
4. Charbonneau, N.L., Dzamba, B.J., Ono, R.N., Keene, D.R., Corson, G.M., Reinhardt, D.P., and Sakai, L.Y. (2003). Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences. J. Biol. Chem. 278:2740-2749. (Pubitemid 36801355)
5. Kielty, C.M., Sherratt, M.J., and Shuttleworth, C.A. (2002). Elastic fibres. J. Cell Sci. 115:2817-2828.
6. Fullmer, H.M., and Lillie, R.D. (1958). The oxytalan fiber: A previously undescribed connective tissue fiber. J. Histochem. Cytochem. 6:425-430.
7. Raviola, G. (1971). The fine structure of the ciliary zonule and ciliary epithelium. With special regard to the organization and insertion of the zonular fibrils. Invest. Ophthalmol. 10:851-869.
8. Hiraoka, M., Inoue, K., Ohtaka-Maruyama, C., Ohsako, S., Kojima, N., Senoo, H., and Takada, M. (2010). Intracapsular organization of ciliary zonules in monkey eyes. Anat. Rec. (Hoboken) 293:1797-1804.
9. Hanssen, E., Franc, S., and Garrone, R. (2001). Synthesis and structural organization of zonular fibers during development and aging. Matrix Biol. 20:77-85. (Pubitemid 32396758)
10. Tsuruga, E., Irie, K., and Yajima, T. (2007). Fibrillin-2 degradation by matrix metalloproteinase-2 in periodontium. J. Dent. Res. 86:352-356.
11. Tsuruga, E., Nakashima, K., Ishikawa, H., Yajima, T., and Sawa, Y. (2009). Stretching modulates oxytalan fibers in human periodontal ligament cells. J. Periodontal Res. 44:170-174.
12. Dietz, H.C., Ramirez, F., and Sakai, L.Y. (1994). Marfan's syndrome and other microfibrillar diseases. Adv. Hum. Genet. 22:153-186.
13. Putnam, E.A., Zhang, H., Ramirez, F., and Milewicz, D.M. (1995). Fibrillin-2 (FBN2) mutations result in the Marfan-like disorder, congenital contractural arachnodactyly. Nat. Genet. 11:456-458.
14. Hollister, D.W., Godfrey, M., Sakai, L.Y., and Pyeritz, R.E. (1990). Immunohistologic abnormalities of the microfibrillarfiber system in the Marfan syndrome. N. Engl. J. Med. 323:152-159. (Pubitemid 20219943)
15. Kielty, C.M., Davies, S.J., Phillips, J.E., Jones, C.J., Shuttleworth, C.A., and Charles, S.J. (1995). Marfan syndrome: Fibrillin expression and microfibrillar abnormalities in a family with predominant ocular defects. J. Med. Genet. 32:1-6.
16. Pessier, A.P., and Potter, K.A. (1996). Ocular pathology in bovine Marfan's syndrome with demonstration of altered fibrillin immunoreactivity in explanted ciliary body cells. Lab. Invest. 75:87-95. (Pubitemid 26250276)
17. Tsuruga, E., Irie, K., Sakakura, Y., and Yajima, T. (2002). Expression of fibrillins and tropoelastin by human gingival and periodontal ligament fibroblasts in vitro. J. Periodontal Res. 37:23-28.
18. Tsuruga, E., Irie, K., and Yajima, T. (2002). Gene expression and accumulation of fibrillin-1, fibrillin-2, and tropoelastin in cultured periodontal fibroblasts. J. Dent. Res. 81:771-775.
19. Tsuruga, E., Irie, K., Sakakura, Y., and Yajima, T. (2002). Tropoelastin expression by periodontal fibroblasts. J. Dent. Res. 81:198-202.
20. Nakatomi, Y., Tsuruga, E., Nakashima, K., Sawa, Y., and Ishikawa, H. (2011). EMILIN-1 regulates the amount of oxytalan fiber formation in periodontal ligaments in vitro. Connect. Tissue Res. 52:30-35.
21. Mecham, R.P., and Davis, E.C. (1994). Elastic fiber structure and assembly. In Extracellular Matrix Assembly and Structure, P.D. Yurchenco, D.E. Birk, and R.P. Mecham (eds.) pp. 281- 314. New York: Academic Press.
22. Sims, M.R. (1973). Oxytalan fiber system of molars in the mouse mandible. J. Dent. Res. 52:797-802.
23. Carta, L., Pereira, L., Arteaga-Solis, E., Lee-Arteaga, S.Y., Lenart, B., Starcher, B., Merkel, C.A., Sukoyan, M., Kerkis, A., Hazeki, N., Keene, D.R., Sakai, L.Y., and Ramirez, F. (2006). Fibrillins 1 and 2 perform partially overlapping functions during aortic development. J. Biol. Chem. 281:8016-8023. (Pubitemid 43847419)
24. Cain, S.A., Morgan, A., Sherratt, M.J., Ball, S.G., Shuttleworth, C.A., and Kielty, C.M. (2006). Proteomic analysis of fibrillin-rich microfibrils. Proteomics 6:111-122. (Pubitemid 43142938)
25. Farnsworth, P.N., Burke, P., Dotto, M.E., and Cinotti, A.A. (1977). Ultrastructural abnormalities in a Marfan's syndrome lens. Arch. Ophthalmol. 95:1601-1606. (Pubitemid 8192938)
26. Bressan, G.M., Daga-Gordini, D., Colombatti, A., Castellani, I., Marigo, V., and Volpin, D. (1993). Emilin, a component of elastic fibers preferentially located at the elastin-microfibrils interface. J. Cell Biol. 121:201-212. (Pubitemid 23097376)
27. Nakamura, T., Ruiz-Lozano, P., Lindner, V., Yabe, D., Taniwaki, M., Furukawa, Y., Kobuke, K., Tashiro, K., Lu, Z., Andon, N.L., Schaub, R., Matsumori, A., Sasayama, S., Chien, K.R., and Honjo, T. (1999). DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries. J. Biol. Chem. 274:22476-22483.
28. Zanetti, M., Braghetta, P., Sabatelli, P., Mura, I., Doliana, R., Colombatti, A., Volpin, D., Bonaldo, P., and Bressan, G.M. (2004). EMILIN-1 deficiency induces elastogenesis and vascular cell defects. Mol. Cell Biol. 24:638-650. (Pubitemid 38057916)
29. Hisanaga, Y., Nakashima, K., Tsuruga, E., Nakatomi, Y., Hatakeyama, Y., Ishikawa, H., and Sawa, Y. (2009). Fibulin- 5 contributes to microfibril assembly in human periodontal ligament cells. Acta Histochem. Cytochem. 42:151-157.
30. Kielty, C.M., Baldock, C., Lee, D., Rock, M.J., Ashworth, J.L., and Shuttleworth, C.A. (2002). Fibrillin: From microfibril assembly to biomechanical function. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 357:207-217. (Pubitemid 34276212)