The vimentin-tubulin binding site peptide (Vim-TBS.58-81) crosses the plasma membrane and enters the nuclei of human glioma cells

International Journal of Pharmaceutics

Volumn 423, Issue 1, 2012, Pages 77-83

  Balzeau, Julien ^a   Peterson, Alan ^a   Eyer, Joel ^a  

^a UNIVERSITÉ D'ANGERS   (France)

Author keywords

Cell penetrating peptide; Glioblastoma; Nuclear localization; Tubulin binding site; Vimentin

Indexed keywords

TUBULIN; VIMENTIN;

BINDING SITE; CELL MEMBRANE; CELL NUCLEUS; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; ENDOCYTOSIS; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ADENOSINE TRIPHOSPHATE; CAVEOLAE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL-PENETRATING PEPTIDES; CHOLERA TOXIN; CYCLIN-DEPENDENT KINASES; CYTOPLASM; DEOXYGLUCOSE; ENDOCYTOSIS; GLIOBLASTOMA; HUMANS; MICROSCOPY, FLUORESCENCE; NEUROFILAMENT PROTEINS; PEPTIDE FRAGMENTS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN INTERACTION DOMAINS AND MOTIFS; SODIUM AZIDE; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TEMPERATURE; TRANSFERRIN; TUBULIN; VIMENTIN;

EID: 84855768645     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.067     Document Type: Conference Paper

References (31)

1. A. Astriab-Fisher, D. Sergueev, M. Fisher, B. Ramsay Shaw, and R.L. Juliano Conjugates of antisense oligonucleotides with the Tat and Antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions Pharm. Res. 19 2002 744 754 (Pubitemid 34686732)
2. R.D. Baker, J. Howl, and I.D. Nicholl A sychnological cell penetrating peptide mimic of p21(WAF1/CIP1) is pro-apoptogenic Peptides 28 2007 731 740 (Pubitemid 46349324)
3. J.A. Barltrop, T.C. Owen, A.H. Cory, and J.G. Cory 5-(3- Carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5- diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans as cell-viability indicators Bioorg. Med. Chem. Lett. 1 1991 611
4. A. Bocquet, R. Berges, R. Frank, P. Robert, A.C. Peterson, and J. Eyer Neurofilaments bind tubulin and modulate its polymerization J. Neurosci. 29 2009 11043 11054
5. A.H. Cory, T.C. Owen, J.A. Barltrop, and J.G. Cory Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture Cancer Commun. 3 1991 207 212
6. N. Darbinian, G.L. Gallia, J. King, L. Del Valle, E.M. Johnson, and K. Khalili Growth inhibition of glioblastoma cells by human Pur alpha J. Cell. Physiol. 189 2001 334 340 (Pubitemid 33063301)
7. D. Derossi, A.H. Joliot, G. Chassaing, and A. Prochiantz The 3rd helix of the Antennapedia homeodomain translocates through biological-membranes J. Biol. Chem. 269 1994 10444 10450 (Pubitemid 24198241)
8. A. Ferrari, V. Pellegrini, C. Arcangeli, A. Fittipaldi, M. Giacca, and F. Beltram Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time Mol. Ther. 8 2003 284 294 (Pubitemid 37062838)
9. A. Fittipaldi, A. Ferrari, M. Zoppe, C. Arcangeli, V. Pellegrini, F. Beltram, and M. Giacca Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins J. Biol. Chem. 278 2003 34141 34149 (Pubitemid 37553255)
10. H. Flores-Rozas, Z. Kelman, F.B. Dean, Z.Q. Pan, J.W. Harper, S.J. Elledge, M. O'Donnell, and J. Hurwitz Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme Proc. Natl. Acad. Sci. U.S.A. 91 1994 8655 8659 (Pubitemid 24273723)
11. A.D. Frankel, and C.O. Pabo Cellular uptake of the Tat protein from human immunodeficiency virus Cell 55 1988 1189 1193 (Pubitemid 19020071)
12. S. Futaki, T. Suzuki, W. Ohashi, T. Yagami, S. Tanaka, K. Ueda, and Y. Sugiura Arginine-rich peptides - an abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery J. Biol. Chem. 276 2001 5836 5840
13. J.A. Hanover, M.C. Willingham, and I. Pastan Kinetics of transit of transferrin and epidermal growth-factor through clathrin-coated membranes Cell 39 1984 283 293 (Pubitemid 15191211)
14. F. Heitz, M.C. Morris, and G. Divita Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics Br. J. Pharmacol. 157 2009 195 206
15. S.V. Heyningen Cholera toxin: interaction of subunits with ganglioside GM1 Science 183 1974 656 657
16. S.L. Lo, and S. Wang An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection Biomaterials 29 2008 2408 2414
17. G. Maga, and U. Hubscher Proliferating cell nuclear antigen (PCNA): a dancer with many partners J. Cell Sci. 116 2003 3051 3060 (Pubitemid 37038954)
18. E.W. Marsh, P.L. Leopold, N.L. Jones, and F.R. Maxfield Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment J. Cell Biol. 129 1995 1509 1522
19. J. Metuzals, and We Mushynsk Electron-microscope and experimental investigations of neurofilamentous network in Deiters neurons - relationship with cell-surface and nuclear-pores J. Cell Biol. 61 1974 701 722
20. M.C. Morris, P. Vidal, L. Chaloin, F. Heitz, and G. Divita A new peptide vector for efficient delivery of oligonucleotides into mammalian cells Nucleic Acid Res. 25 1997 2730 2736 (Pubitemid 27299785)
21. M. Mutoh, F.D. Lung, Y.Q. Long, P.P. Roller, R.S. Sikorski, and P.M. O'Connor A p21(Waf1/Cip1) carboxyl-terminal peptide exhibited cyclin-dependent kinase-inhibitory activity and cytotoxicity when introduced into human cells Cancer Res. 59 1999 3480 3488 (Pubitemid 29334512)
22. U. Niesner, C. Halin, L. Lozzi, M. Günthert, P. Neri, H. Wunderli-Allenspach, L. Zardi, and D. Neri Quantitation of the tumor-targeting properties of antibody fragments conjugated to cell-permeating HIV-1 TAT peptides Bioconjug. Chem. 13 2002 729 736 (Pubitemid 34801114)
23. J.P. Richard, K. Melikov, E. Vives, C. Ramos, B. Verbeure, M.J. Gait, L.V. Chernomordik, and B. Lebleu Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake J. Biol. Chem. 278 2003 585 590 (Pubitemid 36043612)
24. R.L. Shoeman, R. Hartig, and P. Traub Characterization of the nucleic acid binding region of the intermediate filament protein vimentin by fluorescence polarization Biochemistry 38 1999 16802 16809
25. E.L. Snyder, and S.F. Dowdy Recent advances in the use of protein transduction domains for the delivery of peptides, proteins and nucleic acids in vivo Expert Opin. Drug Deliv. 2 2005 43 51 (Pubitemid 40123882)
26. V.P. Torchilin, T.S. Levchenko, R. Rammohan, N. Volodina, B. Papahadjopoulos-Sternberg, and G.G. D'Souza Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes Proc. Natl. Acad. Sci. U.S.A. 100 2003 1972 1977 (Pubitemid 36254558)
27. P. Traub, W.J. Nelson, S. Kuhn, and C.E. Vorgias The interaction in vitro of the intermediate filament protein vimentin with naturally-occurring RNAs and DNAs J. Biol. Chem. 258 1983 1456 1466 (Pubitemid 13101351)
28. P. Traub, C.E. Vorgias, and W.J. Nelson Interaction in vitro of the neurofilament triplet proteins from porcine spinal-cord with natural RNA and DNA Mol. Biol. Rep. 10 1985 129 136
29. E. Vives, P. Brodin, and B. Lebleu A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus J. Biol. Chem. 272 1997 16010 16017 (Pubitemid 27265584)
30. E. Warbrick, D.P. Lane, D.M. Glover, and L.S. Cox A small peptide inhibitor of DNA-replication defines the site of interaction between the cyclin-dependant kinase inhibitor p21(WAF1) and proliferating cell nuclear antigen Curr. Biol. 5 1995 275 282
31. P.G. Yancey, W.V. Rodriqueza, E.P.C. Kilsdonk, G.W. Stoudt, W.J. Johnson, M.C. Phillips, and G.H. Rothblat Cellular cholesterol effect mediated by cyclodextrins - demonstration of kinetic pools and mechanism of efflux J. Biol. Chem. 271 1996 16026 16034 (Pubitemid 26236215)