CD73 protects kidney from ischemia-reperfusion injury through reduction of free radicals

APMIS

Volumn 120, Issue 2, 2012, Pages 130-138

  Jian, Rongrong ^a   Sun, Yong ^a   Wang, Yingjian ^b   Yu, Jerry ^a,c   Zhong, Lingling ^a   Zhou, Ping ^a  

^a FUDAN UNIVERSITY   (China)

^b CHINA JAPAN UNION HOSPITAL OF JILIN UNIVERSITY   (China)

^c UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Adenosine; CD73; Complement activation; Free radicals

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; FREE RADICAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; KIDNEY ISCHEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PURINE SYNTHESIS; RENAL PROTECTION; REPERFUSION INJURY;

5'-NUCLEOTIDASE; ADENOSINE; ANIMALS; FEMALE; HISTOCYTOCHEMISTRY; KIDNEY; MALE; MALONDIALDEHYDE; MICE; MICE, KNOCKOUT; REPERFUSION INJURY;

EID: 84855694483     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2011.02827.x     Document Type: Article

References (48)

1. Zimmermann H. 5′-Nucleotidase: molecular structure and functional aspects. Biochem J 1992;285:345-65.
2. Linden J. Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection. Annu Rev Pharmacol Toxicol 2001;41:775-87.
3. Palmer TM, Stiles GL. Adenosine receptors. Neuropharmacology 1995;34:683-94.
4. Sitkovsky MV, Lukashev D. Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors. Nat Rev Immunol 2005;5:712-21.
5. Sitkovsky MV, Lukashev D, Apasov S, Kojima H, Koshiba M, Caldwell C, et al. Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors. Annu Rev Immunol 2004;22:657-82.
6. Resta R, Yamashita Y, Thompson LF. Ecto-enzyme and signaling functions of lymphocyte CD73. Immunol Rev 1998;161:95-109.
7. Airas L, Niemelä J, Salmi M, Puurunen T, Smith DJ, Jalkanen S. Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule on lymphocytes and endothelial cells. J Cell Biol 1997;136:421-31.
8. Moriwaki Y, Yamamoto T, Higashino K. Enzymes involved in purine metabolism - a review of histochemical localization and functional implications. Histol Histopathol 1999;14:1321-40.
9. Umemoto E, Tanaka T, Kanda H, Jin S, Tohya K, Otani K, et al. Nepmucin, a novel HEV sialomucin, mediates l-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion underflow. J Exp Med 2006;203:1603-14.
10. Baxter GF. Role of adenosine in delayed preconditioning of myocardium. Cardiovasc Res 2002;55:483-94.
11. Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ 2007;14:1315-23.
12. Mubagwa K, Flameng W. Adenosine, adenosine receptors and myocardial protection: an updated overview. Cardiovasc Res 2001;52:25-39.
13. Ohta A, Sitkovsky M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 2001;414:916-20.
14. Lee HT, Xu H, Nasr SH, Schnermann J, Emala CW. A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion. Am J Physiol Renal Physiol 2004;286:F298-306.
15. Day YJ, Huang L, Ye H, Li L, Linden J, Okusa MD. Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. J Immunol 2006;176:3108-14.
16. Day YJ, Huang L, McDuffie MJ, Rosin DL, Ye H, Chen JF, et al. Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. J Clin Invest 2003;112:883-91.
17. Thompson LF, Eltzschig HK, Ibla JC, Van De Wiele CJ, Resta R, Morote-Garcia JC, et al. Crucial role for ecto-5′-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med 2004;200:1395-405.
18. Braun N, Zhu Y, Krieglstein J, Culmsee C, Zimmermann H. Upregulation of the enzyme chain hydrolyzing extracellular ATP after transient forebrain ischemia in the rat. J Neurosci 1998;18:4891-900.
19. Eltzschig HK, Ibla JC, Furuta GT, Leonard MO, Jacobson KA, Enjyoji K, et al. Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med 2003;198:783-96.
20. Delabar U, Kloor D, Luippold G, Mühlbauer B. Simultaneous determination of adenosine, S-adenosylhomocysteine and S-adenosylmethionine in biological samples using solid-phase extraction and high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 1999;724:231-8.
21. Deussen A. Metabolic flux rates of adenosine in the heart. Naunyn-Schmiedeberg's Arch Pharmacol 2000;362:351-63.
22. Rajakumar SV, Lu B, Crikis S, Robson SC, d'Apice AJ, Cowan PJ, et al. Protective role of ecto-5′-nucleotidase CD73 in renal ischemia. J Am Soc Nephrol 2007;18:833-45.
23. Li X, Zhou T, Zhi X, Zhao F, Yin L, Zhou P. Effect of hypoxia/reoxygenation on CD73 (ecto-5′-nucleotidase) in mouse microvessel endothelial cell lines. Microvasc Res 2006;72:48-53.
24. Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, et al. The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med 2008;5:e137.
25. Hart ML, Henn M, Köhler D, Kloor D, Mittelbronn M, Gorzolla IC, et al. Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury. FASEB J 2008;22:2784-97.
26. Gorlach A. Control of adenosine transport by hypoxia. Circ Res 2005;97:1-3.
27. Jaeschke H, Farhood A, Bautista AP, Spolarics Z, Spitzer JJ. Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia. Am J Physiol 1993;264:G801-9.
28. Chakraborti T, Mandal A, Mandal M, Das S, Chakraborti S. Complement activation in heart diseases: role of oxidants. Cell Signal 2000;12:607-17.
29. Chávez-Cartaya RE, DeSola GP, Wright L, Jamieson NV, White DJ. Regulation of the complement cascade by soluble complement receptor type 1. Protective effect in experimental liver ischemia and reperfusion. Transplantation 1995;59:1047-52.
30. de Vries B, Walter SJ, Peutz-Kootstra CJ, Wolfs TG, van Heurn LW, Buurman WA. The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury. Am J Pathol 2004;165:1677-88.
31. Møller-Kristensen M, Wang W, Ruseva M, Thiel S, Nielsen S, Takahashi K, et al. Mannan-binding lectin recognizes structures on ischaemic reperfused mouse kidneys and is implicated in tissue injury. Scand J Immunol 2005;61:426-34.
32. Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, et al. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia. Nat Immunol 2009;10:195-202.
33. Eckle T, Faigle M, Grenz A, Laucher S, Thompson LF, Eltzschig HK. A2B adenosine receptor dampens hypoxia-induced vascular leak. Blood 2008;111:2024-35.
34. Eltzschig HK, Abdulla P, Hoffman E, Hamilton KE, Daniels D, Schönfeld C, et al.HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia. J Exp Med 2005;202:1493-505.
35. Semenza GL. Life with oxygen. Science 2007;318:62-4.
36. Kaelin WG Jr, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell 2008;30:393-402.
37. Synnestvedt K, Furuta GT, Comerford KM, Louis N, Karhausen J, Eltzschig HK, et al. Eeto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest 2002;110:993-1002.
38. Eckle T, Köhler D, Lehmann R, El Kasmi KC, Eltzschig HK. Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning. Circulation 2008;118:166-75.
39. Morote-Garcia JC, Rosenberger P, Kuhlicke J, Eltzschig HK. HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak. Blood 2008;111:5571-80.
40. Morote-Garcia JC, Rosenberger P, Nivillac NM, Coe IR, Eltzschig HK. Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia. Gastroenterology 2009;136:607-18.
41. Eckle T, Krahn T, Grenz A, Kohler D, Mittelbronn M, Ledent C, et al. Cardioprotection by ecto-5′-nucleotidase (CD73) and A2B adenosine receptors. Circulation 2007;115:1581-90.
42. Kong T, Westerman KA, Faigle M, Eltzschig HK, Colgan SP. HIF-dependent induction of adenosine A2B receptor in hypoxia. FASEB J 2006;20:2242-50.
43. Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology 2009;111:904-15.
44. Eckle T, Grenz A, Laucher S, Eltzschig HK. A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest 2008;118:3301-15.
45. Köhler D, Eckle T, Faigle M, Grenz A, Mittelbronn M, Laucher S, et al.CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury. Circulation 2007;116:1784-94.
46. Ly NP, Komatsuzaki K, Fraser IP, Tseng AA, Prodhan P, Moore KJ, et al. Netrin-1 inhibits leukocyte migration in vitro and in vivo. Proc Natl Acad Sci USA 2005;102:14729-34.
47. Hampton MB, Kettle AJ, Winterbourn CC. Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 1998;92:3007-17.
48. Di Pierro D, Tavazzi B, Lazzarino G, Giardina B. Malondialdehyde is a biochemical marker of peroxidative damage in the isolated reperfused rat heart. Mol Cell Biochem 1992;116:193-6.