Can axillary node dissection be omitted in a subset of patients with low local and regional failure rates?

Breast Journal

Volumn 18, Issue 1, 2012, Pages 23-27

  Barkley, Christina ^a   Burstein, Harold ^b   Smith, Barbara ^c   Bellon, Jennifer ^b   Wong, Julia ^b   Gadd, Michele ^c   Taghian, Alphonse ^c   Winer, Eric ^b   Iglehart, James Dirk ^a   Harris, Jay ^c   Golshan, Mehra ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

axillary node dissection; breast cancer; sentinel node biopsy

Indexed keywords

TRASTUZUMAB;

ADULT; ARTICLE; AXILLARY NODE DISSECTION; BREAST CANCER; CANCER HORMONE THERAPY; CANCER RADIOTHERAPY; CLINICAL DECISION MAKING; DISTANT METASTASIS; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MICROMETASTASIS; PATIENT SELECTION; SENTINEL LYMPH NODE BIOPSY; SURGICAL TECHNIQUE; TREATMENT FAILURE;

AXILLA; BREAST NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM MICROMETASTASIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RETROSPECTIVE STUDIES; SENTINEL LYMPH NODE BIOPSY; TREATMENT OUTCOME;

EID: 84855682346     PISSN: 1075122X     EISSN: 15244741     Source Type: Journal    
DOI: 10.1111/j.1524-4741.2011.01178.x     Document Type: Article

References (33)

1. Krag D, Single R,. Breast cancer survival according to number of nodes removed. Ann Surg Oncol 2003; 10: 1152-9. (Pubitemid 40486809)
2. Grube BJ, Giuliano AE,. Observation of the breast cancer patient with a tumor-positive sentinel node: implications of the ACOSOG Z0011 trial. Semin Surg Oncol 2001; 20: 23-237.
3. Morrow M,. Axillary dissection: when and how radical? Semin Surg Oncol 1996; 12: 321-7. (Pubitemid 26300010)
4. Bilimoria KY, Bentrem DJ, Hansen NM, et al. Comparison of sentinel lymph node biopsy alone and completion axillary lymph node dissection for node-positive breast cancer. J Clin Oncol 2009; 27: 2946-53.
5. Hwang RF, Gonzalez-Angulo AM, Yi M, et al. Low locoregional failure rates in selected breast cancer patients with tumor-positive sentinel lymph nodes who do not undergo completion axillary dissection. Cancer 2007; 110: 723-30. (Pubitemid 47257646)
6. Jeruss JS, Winchester DJ, Sener SF, et al. Axillary recurrence after sentinel node biopsy. Ann Surg Oncol 2005; 12: 34-40. (Pubitemid 40486639)
7. Naik AM, Fey J, Gemignani M, et al. The risk of axillary relapse after sentinel lymph node biopsy for breast cancer is comparable with that of axillary node dissection: a follow-up study of 4008 procedures. Ann Surg 2004; 240: 462-8.
8. Fant JS, Grant MD, Knox SM, et al. Preliminary outcome analysis in patients with breast cancer and a positive sentinel node who declined axillary dissection. Ann Surg Oncol 2003; 10: 126-30. (Pubitemid 40485931)
9. Gadd M, Harris J, Taghian A, et al. Prospective study of axillary radiation without axillary dissection for breast cancer patients with a positive sentinel node. Presented at: The Annual San Antonio Breast Cancer Symposium, San Antonio, TX, USA, 8-11 Dec 2005 (abstract 25).
10. Straver ME, Meijnen P, van Tienhoven G, et al. Sentinel node identification rate and nodal involvement in the EORTC 10981-22023 AMAROS trial. Ann Surg Oncol 2010; 17: 1854-61.
11. Mabry H, Giuliano AE,. Sentinel node mapping for breast cancer: progress to date and prospects for the future. Surg Oncol Clin N Am 2007; 16: 55-70.
12. Golshan M, Smith B,. Prevention and management of arm lymphedema in the patient with breast cancer. J Support Oncol 2006; 4: 381-6. (Pubitemid 44541012)
13. Van Zee KJ, Manasseh DM, Bevilacqua JL,. A nomogram for predicting the likelihood of additional nodal metastases in breast cancer patients with a positive sentinel node biopsy. Ann Surg Oncol 2003; 10: 1140-51. (Pubitemid 40486808)
14. Gur AS, Unal B, Johnson R, et al. Predictive probability of four different breast cancer nomograms for nonsentinel node metastasis in positive sentinel node biopsy. J Am Coll Surg 2009; 208: 229-35.
15. Soni NK, Carmalt HL, Gillett DJ, et al. Evaluation of a breast cancer nomogram for prediction of non-sentinel lymph node positivity. Eur J Surg Oncol 2005; 31: 958-64. (Pubitemid 41671108)
16. Smidt ML, Kuster DM, van der Wilt GJ, et al. Can the memorial sloan kettering nomogram predict the likelihood of nonsentinel lymph node metastasis in breast cancer patients in the Netherlands? Ann Surg Oncol 2005; 12: 1066-72. (Pubitemid 41660683)
17. de Boer M, van Deurzen CH, van Dijck JA, et al. Micrometastases or isolated cells and the outcome of breast cancer. N Eng J Med 2009; 361: 653-6.
18. Hansen NM, Grube B, Ye X, et al. Impact of micrometastases in the sentinel node of patients with invasive breast cancer. J Clin Oncol 2009; 27: 4679-84.
19. Tjan-Heijnen VC, Pepels MJ, de Boer M, et al. Impact of omission of completion axillary node dissection (cALND) or axillary radiotherapy (ax RT) in breast cancer patients with macrometastatic (pN1mi) or isolated tumor cells (pN0i+) in the sentinel lymph node (SN): results from the Mirror Study. JCO 2009; 27: 18S. (June 20 supplement).
20. Giuliano AE, McCall L, Beitsch P, et al. Locoregional recurrence after sentinel node dissection with or without axillary dissection in patients with sentinel node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial. Ann Surg 2010; 252: 426-32. Discussion 432-3.
21. Galper S, Recht A, Silver B, Bernardo MV, Gelman R, Wong J,. Is radiation alone adequate treatment to the axilla for patients with limited axillary surgery? Implications for treatment after a positive sentinel node biopsy. Int J Radiat Oncol Biol Phys 2000; 48: 125-32. (Pubitemid 30488222)
22. Ganaraj A, Kuhn JA, Jones RC, Grant MD, Andrews VR, Knox SM,. Predictors for nonsentinel node involvement in breast cancer patients with micrometastases in the sentinel lymph node. Proc (Bayl Univ Med Cent) 2003; 16: 3-6.
23. Guenther JM, Hansen NM, DiFronzo LA, et al. Axillary dissection is not required for all patients with breast cancer and positive sentinel nodes. Arch Surg 2003; 138: 52-6. (Pubitemid 36055648)
24. Fournier K, Schiller A, Perry RR, Laronga C,. Micrometastasis in the sentinel lymph node of breast cancer does not mandate completion axillary dissection. Ann Surg 2004; 239: 859-63.
25. Fan YG, Tan YY, Wu CT, et al. The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer. Ann Surg Oncol 2005; 12: 705-11.
26. Schrenk P, Konstantiniuk P, Wolfi S, Bogner S, Haid A, Nemes C,. Prediction of non-sentinel lymph node status in breast cancer with a micrometastatic sentinel node. Br J Surg 2005; 92: 707-13. (Pubitemid 40863189)
27. Carlo JT, Grant MD, Knox SM, Jones RC, Hamilton CS, Livingston SA,. Survival analysis following sentinel lymph node biopsy: a validation trial demonstrating its accuracy in staging early breast cancer. Proc (Bayl Univ Med Cent) 2005; 18: 103-7.
28. Chagpar A, Middleton LP, Sahin AA, Meric-Bernstam F, Kuerer HM, Feig BW,. Clinical outcome of patients with lymph node-negative breast carcinoma who have sentinel lymph node metastasis detected by immunohistochemistry. Cancer 2005; 103: 1581-6. (Pubitemid 40490018)
29. Takei H, Suemasu K, Kurosumi M, et al. Recurrence after sentinel lymph node biopsy with or without axillary lymph node dissection in patients with breast cancer. Breast Cancer 2007; 14: 16-24.
30. Zakaria S, Pantvaidya G, Reynolds CA, et al. Sentinel node positive breast cancer patients who do not undergo axillary dissections: are they different? Surgery 2008; 143: 641-7.
31. Langer I, Guller U, Berclaz G, Koechli OR, Schaer G, Fehr MK,. Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN and completion axillary lymph node dissection after breast cancer surgery: a prospective Swiss multicenter study on 659 patients. Ann Surg 2007; 245: 452-61. (Pubitemid 46673142)
32. Golshan M, Bellon J, Smith B, et al. Can axillary node dissection be omitted in a subset of patients with low local and regional failure rates? American Society of Clinical Oncology Breast Cancer Symposium, San Francisco, CA, USA, 8-10 October 2009 (Abstract 219).
33. Pernas S, Gil M, Benitez A, et al. Avoiding axillary treatment in sentinel lymph node micrometastases of breast cancer: a prospective analysis of axillary or distant recurrence. Ann Surg Oncol 2010; 17: 772-7.