-
1
-
-
21144438189
-
Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer
-
DOI 10.1200/JCO.2005.01.529
-
Smith MR, Kabbinavar F, Saad F, Hussain A, Gittelman MC, Bilhartz DL, Wynne C, Murray R, Zinner NR, Schulman C, Linnartz R, Zheng M, Goessl C, Hei YJ, Small EJ, Cook R, Higano CS,. Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer. J Clin Oncol 2005; 23: 2918-2925. (Pubitemid 46224110)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.13
, pp. 2918-2925
-
-
Smith, M.R.1
Kabbinavar, F.2
Saad, F.3
Hussain, A.4
Gittelman, M.C.5
Bilhartz, D.L.6
Wynne, C.7
Murray, R.8
Zinner, N.R.9
Schulman, C.10
Linnartz, R.11
Zheng, M.12
Goessl, C.13
Hei, Y.-J.14
Small, E.J.15
Cook, R.16
Higano, C.S.17
-
2
-
-
58149302446
-
Progression of prostate cancer: Multiple pathways to androgen independence
-
Devlin HL, Mudryj M,. Progression of prostate cancer: Multiple pathways to androgen independence. Cancer Lett 2009; 274: 177-186.
-
(2009)
Cancer Lett
, vol.274
, pp. 177-186
-
-
Devlin, H.L.1
Mudryj, M.2
-
3
-
-
69449095475
-
Stroma-epithelium crosstalk in prostate cancer
-
Niu YN, Xia SJ,. Stroma-epithelium crosstalk in prostate cancer. Asian J Androl 2009; 11: 28-35.
-
(2009)
Asian J Androl
, vol.11
, pp. 28-35
-
-
Niu, Y.N.1
Xia, S.J.2
-
4
-
-
27644452640
-
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
-
DOI 10.1158/1078-0432.CCR-05-0525
-
Titus MA, Schell MJ, Lih FB, Tomer KB, Mohler JL,. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 2005; 11: 4653-4657. (Pubitemid 41557182)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.13
, pp. 4653-4657
-
-
Titus, M.A.1
Schell, M.J.2
Lih, F.B.3
Tomer, K.B.4
Mohler, J.L.5
-
5
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, Febbo PG, Balk SP,. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 2006; 66: 2815-2825.
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
Febbo, P.G.7
Balk, S.P.8
-
6
-
-
53749090666
-
Phase i clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
Attard G, Reid AH, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper CS, Kaye SB, Dearnaley D, Lee G, de Bono JS,. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol 2008; 26: 4563-4571.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4563-4571
-
-
Attard, G.1
Reid, A.H.2
Yap, T.A.3
Raynaud, F.4
Dowsett, M.5
Settatree, S.6
Barrett, M.7
Parker, C.8
Martins, V.9
Folkerd, E.10
Clark, J.11
Cooper, C.S.12
Kaye, S.B.13
Dearnaley, D.14
Lee, G.15
De Bono, J.S.16
-
7
-
-
77951523950
-
Phase i clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy
-
Ryan CJ, Smith MR, Fong L, Rosenberg JE, Kantoff P, Raynaud F, Martins V, Lee G, Kheoh T, Kim J, Molina A, Small EJ,. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. J Clin Oncol 2010; 28: 1481-1488.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1481-1488
-
-
Ryan, C.J.1
Smith, M.R.2
Fong, L.3
Rosenberg, J.E.4
Kantoff, P.5
Raynaud, F.6
Martins, V.7
Lee, G.8
Kheoh, T.9
Kim, J.10
Molina, A.11
Small, E.J.12
-
8
-
-
77951518711
-
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
-
Reid AH, Attard G, Danila DC, Oommen NB, Olmos D, Fong PC, Molife LR, Hunt J, Messiou C, Parker C, Dearnaley D, Swennenhuis JF, Terstappen LW, Lee G, Kheoh T, Molina A, Ryan CJ, Small E, Scher HI, de Bono JS,. Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. J Clin Oncol 2010; 28: 1489-1495.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1489-1495
-
-
Reid, A.H.1
Attard, G.2
Danila, D.C.3
Oommen, N.B.4
Olmos, D.5
Fong, P.C.6
Molife, L.R.7
Hunt, J.8
Messiou, C.9
Parker, C.10
Dearnaley, D.11
Swennenhuis, J.F.12
Terstappen, L.W.13
Lee, G.14
Kheoh, T.15
Molina, A.16
Ryan, C.J.17
Small, E.18
Scher, H.I.19
De Bono, J.S.20
more..
-
9
-
-
68949094223
-
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
Attard G, Reid AH, A'Hern R, Parker C, Oommen NB, Folkerd E, Messiou C, Molife LR, Maier G, Thompson E, Olmos D, Sinha R, Lee G, Dowsett M, Kaye SB, Dearnaley D, Kheoh T, Molina A, de Bono JS,. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 2009; 27: 3742-3748.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
Parker, C.4
Oommen, N.B.5
Folkerd, E.6
Messiou, C.7
Molife, L.R.8
Maier, G.9
Thompson, E.10
Olmos, D.11
Sinha, R.12
Lee, G.13
Dowsett, M.14
Kaye, S.B.15
Dearnaley, D.16
Kheoh, T.17
Molina, A.18
De Bono, J.S.19
-
10
-
-
77951591066
-
Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer
-
Danila DC, Morris MJ, de Bono JS, Ryan CJ, Denmeade SR, Smith MR, Taplin ME, Bubley GJ, Kheoh T, Haqq C, Molina A, Anand A, Koscuiszka M, Larson SM, Schwartz LH, Fleisher M, Scher HI,. Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. J Clin Oncol 2010; 28: 1496-1501.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1496-1501
-
-
Danila, D.C.1
Morris, M.J.2
De Bono, J.S.3
Ryan, C.J.4
Denmeade, S.R.5
Smith, M.R.6
Taplin, M.E.7
Bubley, G.J.8
Kheoh, T.9
Haqq, C.10
Molina, A.11
Anand, A.12
Koscuiszka, M.13
Larson, S.M.14
Schwartz, L.H.15
Fleisher, M.16
Scher, H.I.17
-
11
-
-
78649919788
-
Abiraterone acetate (AA) plus low dose prednisone (P) improves overall survival (OS) in patients (PTS) with metastatic castration-resistant prostate cancer (MCRPC) who have progressed after docetaxel-based chemotherapy (CHEMO): Results of COU-AA-301, a randomized, double-blind, placebo-controlled phase III study [abstract]
-
on behalf of the COU-AA-301 Investigators.:. Abstract LBA5.
-
de Bono JS, Logothetis CJ, Fizazi K, North S, Chu L, Chi KN, Kheoh T, Haqq C, Molina A, Scher HI, on behalf of the COU-AA-301 Investigators. Abiraterone acetate (AA) plus low dose prednisone (P) improves overall survival (OS) in patients (PTS) with metastatic castration-resistant prostate cancer (MCRPC) who have progressed after docetaxel-based chemotherapy (CHEMO): Results of COU-AA-301, a randomized, double-blind, placebo-controlled phase III study [abstract]. Ann Oncol 2010; 21: viii3. Abstract LBA5.
-
(2010)
Ann Oncol
, vol.21
-
-
De Bono, J.S.1
Logothetis, C.J.2
Fizazi, K.3
North, S.4
Chu, L.5
Chi, K.N.6
Kheoh, T.7
Haqq, C.8
Molina, A.9
Scher, H.I.10
-
13
-
-
79851511355
-
Safety, pharmacokinetics, and efficacy of TAK-700 in castration- resistant, metastatic prostate cancer: A phase I/II, open-label study
-
Abstract presented at March 5-7 San Francisco, CA
-
Dreicer R, Agus DB, MacVicar GR, MacLean D, Zhang T, Stadler WM,. Safety, pharmacokinetics, and efficacy of TAK-700 in castration-resistant, metastatic prostate cancer: A phase I/II, open-label study. Abstract presented at: 2010 Genitourinary Cancers Symposium; March 5-7, 2010; San Francisco, CA.
-
(2010)
2010 Genitourinary Cancers Symposium
-
-
Dreicer, R.1
Agus, D.B.2
MacVicar, G.R.3
MacLean, D.4
Zhang, T.5
Stadler, W.M.6
-
14
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL,. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 2009; 324: 787-790.
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
Chen, Y.4
Watson, P.A.5
Arora, V.6
Wongvipat, J.7
Smith-Jones, P.M.8
Yoo, D.9
Kwon, A.10
Wasielewska, T.11
Welsbie, D.12
Chen, C.D.13
Higano, C.S.14
Beer, T.M.15
Hung, D.T.16
Scher, H.I.17
Jung, M.E.18
Sawyers, C.L.19
-
15
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
-
Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E, Rathkopf D, Shelkey J, Yu EY, Alumkal J, Hung D, Hirmand M, Seely L, Morris MJ, Danila DC, Humm J, Larson S, Fleisher M, Sawyers CL,. Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study. Lancet 2010; 375: 1437-1446.
-
(2010)
Lancet
, vol.375
, pp. 1437-1446
-
-
Scher, H.I.1
Beer, T.M.2
Higano, C.S.3
Anand, A.4
Taplin, M.E.5
Efstathiou, E.6
Rathkopf, D.7
Shelkey, J.8
Yu, E.Y.9
Alumkal, J.10
Hung, D.11
Hirmand, M.12
Seely, L.13
Morris, M.J.14
Danila, D.C.15
Humm, J.16
Larson, S.17
Fleisher, M.18
Sawyers, C.L.19
-
16
-
-
0034772250
-
Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
-
George DJ, Halabi S, Shepard TF, Vogelzang NJ, Hayes DF, Small EJ, Kantoff PW,. Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 2001; 7: 1932-1936. (Pubitemid 32994827)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.7
, pp. 1932-1936
-
-
George, D.J.1
Halabi, S.2
Shepard, T.F.3
Vogelzang, N.J.4
Hayes, D.F.5
Small, E.J.6
Kantoff, P.W.7
-
17
-
-
0027717345
-
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma
-
Weidner N, Carroll PR, Flax J, Blumenfeld W, Folkman J,. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 1993; 143: 401-409. (Pubitemid 24058195)
-
(1993)
American Journal of Pathology
, vol.143
, Issue.2
, pp. 401-409
-
-
Weidner, N.1
Carroll, P.R.2
Flax, J.3
Blumenfeld, W.4
Folkman, J.5
-
18
-
-
77951644363
-
Phase II trial of bevacizumab, thalidomide, docetaxel, and prednisone in patients with metastatic castration-resistant prostate cancer
-
Ning YM, Gulley JL, Arlen PM, Woo S, Steinberg SM, Wright JJ, Parnes HL, Trepel JB, Lee MJ, Kim YS, Sun H, Madan RA, Latham L, Jones E, Chen CC, Figg WD, Dahut WL,. Phase II trial of bevacizumab, thalidomide, docetaxel, and prednisone in patients with metastatic castration-resistant prostate cancer. J Clin Oncol 2010; 28: 2070-2076.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2070-2076
-
-
Ning, Y.M.1
Gulley, J.L.2
Arlen, P.M.3
Woo, S.4
Steinberg, S.M.5
Wright, J.J.6
Parnes, H.L.7
Trepel, J.B.8
Lee, M.J.9
Kim, Y.S.10
Sun, H.11
Madan, R.A.12
Latham, L.13
Jones, E.14
Chen, C.C.15
Figg, W.D.16
Dahut, W.L.17
-
19
-
-
77955714649
-
A randomized, double-blind, placebo-controlled phase III trial comparing docetaxel, prednisone, and placebo with docetaxel, prednisone, and bevacizumab in men with metastatic castration-resistant prostate cancer (mCRPC): Survival results of CALGB 90401 [abstract]
-
Abstract LBA4511.
-
Kelly WK, Halabi S, Carducci MA, George DJ, Mahoney JF, Stadler WM, Morris MJ, Kantoff PW, Monk JP, Small EJ,. A randomized, double-blind, placebo-controlled phase III trial comparing docetaxel, prednisone, and placebo with docetaxel, prednisone, and bevacizumab in men with metastatic castration-resistant prostate cancer (mCRPC): Survival results of CALGB 90401 [abstract]. J Clin Oncol 2010; 28: Abstract LBA4511.
-
(2010)
J Clin Oncol
, vol.28
-
-
Kelly, W.K.1
Halabi, S.2
Carducci, M.A.3
George, D.J.4
Mahoney, J.F.5
Stadler, W.M.6
Morris, M.J.7
Kantoff, P.W.8
Monk, J.P.9
Small, E.J.10
-
20
-
-
0037143764
-
VEGF-Trap: A VEGF blocker with potent antitumor effects
-
DOI 10.1073/pnas.172398299
-
Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, Boland P, Leidich R, Hylton D, Burova E, Ioffe E, Huang T, Radziejewski C, Bailey K, Fandl JP, Daly T, Wiegand SJ, Yancopoulos GD, Rudge JS,. VEGF-Trap: A VEGF blocker with potent antitumor effects. Proc Natl Acad Sci USA 2002; 99: 11393-11398. (Pubitemid 34920936)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.17
, pp. 11393-11398
-
-
Holash, J.1
Davis, S.2
Papadopoulos, N.3
Croll, S.D.4
Ho, L.5
Russell, M.6
Boland, P.7
Leidich, R.8
Hylton, D.9
Burova, E.10
Ioffe, E.11
Huang, T.12
Radziejewski, C.13
Bailey, K.14
Fandl, J.P.15
Daly, T.16
Wiegand, S.J.17
Yancopoulos, G.D.18
Rudge, J.S.19
-
21
-
-
74949119167
-
Phase i study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors
-
Lockhart AC, Rothenberg ML, Dupont J, Cooper W, Chevalier P, Sternas L, Buzenet G, Koehler E, Sosman JA, Schwartz LH, Gultekin DH, Koutcher JA, Donnelly EF, Andal R, Dancy I, Spriggs DR, Tew WP,. Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors. J Clin Oncol 2010; 28: 207-214.
-
(2010)
J Clin Oncol
, vol.28
, pp. 207-214
-
-
Lockhart, A.C.1
Rothenberg, M.L.2
Dupont, J.3
Cooper, W.4
Chevalier, P.5
Sternas, L.6
Buzenet, G.7
Koehler, E.8
Sosman, J.A.9
Schwartz, L.H.10
Gultekin, D.H.11
Koutcher, J.A.12
Donnelly, E.F.13
Andal, R.14
Dancy, I.15
Spriggs, D.R.16
Tew, W.P.17
-
22
-
-
74949101370
-
Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors
-
Tew WP, Gordon M, Murren J, Dupont J, Pezzulli S, Aghajanian C, Sabbatini P, Mendelson D, Schwartz L, Gettinger S, Psyrri A, Cedarbaum JM, Spriggs DR,. Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors. Clin Cancer Res 2010; 16: 358-366.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 358-366
-
-
Tew, W.P.1
Gordon, M.2
Murren, J.3
Dupont, J.4
Pezzulli, S.5
Aghajanian, C.6
Sabbatini, P.7
Mendelson, D.8
Schwartz, L.9
Gettinger, S.10
Psyrri, A.11
Cedarbaum, J.M.12
Spriggs, D.R.13
-
23
-
-
77952223624
-
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
-
Olsson A, Bjork A, Vallon-Christersson J, Isaacs JT, Leanderson T,. Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. Mol Cancer 2010; 9: 107.
-
(2010)
Mol Cancer
, vol.9
, pp. 107
-
-
Olsson, A.1
Bjork, A.2
Vallon-Christersson, J.3
Isaacs, J.T.4
Leanderson, T.5
-
24
-
-
70349952393
-
Open-label, clinical phase i studies of tasquinimod in patients with castration-resistant prostate cancer
-
Bratt O, Haggman M, Ahlgren G, Nordle O, Bjork A, Damber JE,. Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer. Br J Cancer 2009; 101: 1233-1240.
-
(2009)
Br J Cancer
, vol.101
, pp. 1233-1240
-
-
Bratt, O.1
Haggman, M.2
Ahlgren, G.3
Nordle, O.4
Bjork, A.5
Damber, J.E.6
-
25
-
-
77955710046
-
A randomized, multicenter, international phase II study of tasquinimod in chemotherapy naïve patients with metastatic castrate-resistant prostate cancer (CRPC) [abstract]
-
Abstract 4510.
-
Pili R, Haggman M, Stadler WM, Gingrich JR, Assikis VJ, Björk A, Forsberg G, Carducci MA, Armstrong AJ,. A randomized, multicenter, international phase II study of tasquinimod in chemotherapy naïve patients with metastatic castrate-resistant prostate cancer (CRPC) [abstract]. J Clin Oncol 2010; 28: Abstract 4510.
-
(2010)
J Clin Oncol
, vol.28
-
-
Pili, R.1
Haggman, M.2
Stadler, W.M.3
Gingrich, J.R.4
Assikis, V.J.5
Björk, A.6
Forsberg, G.7
Carducci, M.A.8
Armstrong, A.J.9
-
27
-
-
69249203584
-
Castration-resistant prostate cancer: From new pathophysiology to new treatment targets
-
Chi KN, Bjartell A, Dearnaley D, Saad F, Schroder FH, Sternberg C, Tombal B, Visakorpi T,. Castration-resistant prostate cancer: From new pathophysiology to new treatment targets. Eur Urol 2009; 56: 594-605.
-
(2009)
Eur Urol
, vol.56
, pp. 594-605
-
-
Chi, K.N.1
Bjartell, A.2
Dearnaley, D.3
Saad, F.4
Schroder, F.H.5
Sternberg, C.6
Tombal, B.7
Visakorpi, T.8
-
28
-
-
35648968713
-
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
-
DOI 10.1002/cncr.22996
-
Carducci MA, Saad F, Abrahamsson PA, Dearnaley DP, Schulman CC, North SA, Sleep DJ, Isaacson JD, Nelson JB,. A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer. Cancer 2007; 110: 1959-1966. (Pubitemid 350036854)
-
(2007)
Cancer
, vol.110
, Issue.9
, pp. 1959-1966
-
-
Carducci, M.A.1
Saad, F.2
Abrahamsson, P.-A.3
Dearnaley, D.P.4
Schulman, C.C.5
North, S.A.6
Sleep, D.J.7
Isaacson, J.D.8
Nelson, J.B.9
-
29
-
-
55549112219
-
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
-
Nelson JB, Love W, Chin JL, Saad F, Schulman CC, Sleep DJ, Qian J, Steinberg J, Carducci M,. Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 2008; 113: 2478-2487.
-
(2008)
Cancer
, vol.113
, pp. 2478-2487
-
-
Nelson, J.B.1
Love, W.2
Chin, J.L.3
Saad, F.4
Schulman, C.C.5
Sleep, D.J.6
Qian, J.7
Steinberg, J.8
Carducci, M.9
-
30
-
-
51449109131
-
ZD4054: A specific endothelin A receptor antagonist with promising activity in metastatic castration-resistant prostate cancer
-
Warren R, Liu G,. ZD4054: A specific endothelin A receptor antagonist with promising activity in metastatic castration-resistant prostate cancer. Expert Opin Invest Drugs 2008; 17: 1237-1245.
-
(2008)
Expert Opin Invest Drugs
, vol.17
, pp. 1237-1245
-
-
Warren, R.1
Liu, G.2
-
31
-
-
62649134676
-
Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial
-
James ND, Caty A, Borre M, Zonnenberg BA, Beuzeboc P, Morris T, Phung D, Dawson NA,. Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial. Eur Urol 2009; 55: 1112-1123.
-
(2009)
Eur Urol
, vol.55
, pp. 1112-1123
-
-
James, N.D.1
Caty, A.2
Borre, M.3
Zonnenberg, B.A.4
Beuzeboc, P.5
Morris, T.6
Phung, D.7
Dawson, N.A.8
-
32
-
-
84855688378
-
Zibotentan (ZD4054): A specific endothelin-A receptor antagonist with potential for the treatment of castrate-resistant prostate cancer
-
Poster presented at December 3-4 Bethesda, MD
-
Dawson NA, Growcott JW, Morris T, Phung DH, James ND,. Zibotentan (ZD4054): A specific endothelin-A receptor antagonist with potential for the treatment of castrate-resistant prostate cancer. Poster presented at: Society of Urologic Oncology's 10 Annual Meeting in Conjunction with the World Urological Oncology Federation; December 3-4, 2009; Bethesda, MD.
-
(2009)
Society of Urologic Oncology's 10 Annual Meeting in Conjunction with the World Urological Oncology Federation
-
-
Dawson, N.A.1
Growcott, J.W.2
Morris, T.3
Phung, D.H.4
James, N.D.5
-
35
-
-
73149115110
-
Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
-
Yu EY, Wilding G, Posadas E, Gross M, Culine S, Massard C, Morris MJ, Hudes G, Calabro F, Cheng S, Trudel GC, Paliwal P, Sternberg CN,. Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer. Clin Cancer Res 2009; 15: 7421-7428.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7421-7428
-
-
Yu, E.Y.1
Wilding, G.2
Posadas, E.3
Gross, M.4
Culine, S.5
Massard, C.6
Morris, M.J.7
Hudes, G.8
Calabro, F.9
Cheng, S.10
Trudel, G.C.11
Paliwal, P.12
Sternberg, C.N.13
-
36
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1731
-
Nam S, Kim D, Cheng JQ, Zhang S, Lee JH, Buettner R, Mirosevich J, Lee FY, Jove R,. Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res 2005; 65: 9185-9189. (Pubitemid 41507982)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.-H.5
Buettner, R.6
Mirosevich, J.7
Lee, F.Y.8
Jove, R.9
-
37
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with Sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
DOI 10.1200/JCO.2005.04.5252
-
Small EJ, Schellhammer PF, Higano CS, Redfern CH, Nemunaitis JJ, Valone FH, Verjee SS, Jones LA, Hershberg RM,. Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 2006; 24: 3089-3094. (Pubitemid 46638945)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.19
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
Redfern, C.H.4
Nemunaitis, J.J.5
Valone, F.H.6
Verjee, S.S.7
Jones, L.A.8
Hershberg, R.M.9
-
38
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammer PF, Small EJ, Burch PA, Nemunaitis J, Yuh L, Provost N, Frohlich MW,. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 2009; 115: 3670-3679.
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
Burch, P.A.4
Nemunaitis, J.5
Yuh, L.6
Provost, N.7
Frohlich, M.W.8
-
39
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
for the IMPACT Study Investigators.
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, Redfern CH, Ferrari AC, Dreicer R, Sims RB, Xu Y, Frolich MW, Schellhammer PF, for the IMPACT Study Investigators. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363: 411-422.
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
Redfern, C.H.7
Ferrari, A.C.8
Dreicer, R.9
Sims, R.B.10
Xu, Y.11
Frolich, M.W.12
Schellhammer, P.F.13
-
40
-
-
30544449854
-
A phase i trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer
-
Dipaola RS, Plante M, Kaufman H, Petrylak DP, Israeli R, Lattime E, Manson K, Schuetz T,. A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer. J Transl Med 2006; 4: 1.
-
(2006)
J Transl Med
, vol.4
, pp. 1
-
-
Dipaola, R.S.1
Plante, M.2
Kaufman, H.3
Petrylak, D.P.4
Israeli, R.5
Lattime, E.6
Manson, K.7
Schuetz, T.8
-
41
-
-
77949895922
-
Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer
-
Kantoff PW, Schuetz TJ, Blumenstein BA, Glode LM, Bilhartz DL, Wyand M, Manson K, Panicali DL, Laus R, Schlom J, Dahut WL, Arlen PM, Gulley JL, Godfrey WR,. Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol 2010; 28: 1099-1105.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1099-1105
-
-
Kantoff, P.W.1
Schuetz, T.J.2
Blumenstein, B.A.3
Glode, L.M.4
Bilhartz, D.L.5
Wyand, M.6
Manson, K.7
Panicali, D.L.8
Laus, R.9
Schlom, J.10
Dahut, W.L.11
Arlen, P.M.12
Gulley, J.L.13
Godfrey, W.R.14
-
42
-
-
34250223096
-
A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer
-
DOI 10.1158/1078-0432.CCR-06-2318
-
Small EJ, Tchekmedyian NS, Rini BI, Fong L, Lowy I, Allison JP,. A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res 2007; 13: 1810-1815. (Pubitemid 46952950)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.6
, pp. 1810-1815
-
-
Small, E.J.1
Tchekmedyian, N.S.2
Rini, B.I.3
Fong, L.4
Lowy, I.5
Allison, J.P.6
-
43
-
-
78449265248
-
A randomized phase II study of ipilimumab with androgen ablation compared with androgen ablation alone in patients with advanced prostate cancer
-
Abstract presented at March 5-7 San Francisco, CA
-
Tollefson MK, Karnes RJ, Thompson RH, Granberg CF, Hillman DW, Breau RH, Allison JP, Blute ML, Kwon ED,. A randomized phase II study of ipilimumab with androgen ablation compared with androgen ablation alone in patients with advanced prostate cancer. Abstract presented at: The American Society of Clinical Oncology Genitourinary Cancers Symposium; March 5-7, 2010; San Francisco, CA.
-
(2010)
The American Society of Clinical Oncology Genitourinary Cancers Symposium
-
-
Tollefson, M.K.1
Karnes, R.J.2
Thompson, R.H.3
Granberg, C.F.4
Hillman, D.W.5
Breau, R.H.6
Allison, J.P.7
Blute, M.L.8
Kwon, E.D.9
-
44
-
-
69049105440
-
Denosumab in men receiving androgen-deprivation therapy for prostate cancer
-
Smith MR, Egerdie B, Hernandez TN, Feldman R, Tammela TL, Saad F, Heracek J, Szwedowski M, Ke C, Kupic A, Leder BZ, Goessl C,. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med 2009; 361: 745-755.
-
(2009)
N Engl J Med
, vol.361
, pp. 745-755
-
-
Smith, M.R.1
Egerdie, B.2
Hernandez, T.N.3
Feldman, R.4
Tammela, T.L.5
Saad, F.6
Heracek, J.7
Szwedowski, M.8
Ke, C.9
Kupic, A.10
Leder, B.Z.11
Goessl, C.12
-
45
-
-
78349290889
-
A randomized phase III trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer [abstract]
-
Abstract LBA4507.
-
Fizazi K, Carducci MA, Smith MR, Damião R, Brown JE, Karsh L, Milecki P, Wang H, Dansey RD, Goessl CD,. A randomized phase III trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer [abstract]. J Clin Oncol 2010; 28: Abstract LBA4507.
-
(2010)
J Clin Oncol
, vol.28
-
-
Fizazi, K.1
Carducci, M.A.2
Smith, M.R.3
Damião, R.4
Brown, J.E.5
Karsh, L.6
Milecki, P.7
Wang, H.8
Dansey, R.D.9
Goessl, C.D.10
-
46
-
-
59449102526
-
Phase i and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
-
Mita AC, Denis LJ, Rowinsky EK, Debono JS, Goetz AD, Ochoa L, Forouzesh B, Beeram M, Patnaik A, Molpus K, Semiond D, Besenval M, Tolcher AW,. Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clin Cancer Res 2009; 15: 723-730.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 723-730
-
-
Mita, A.C.1
Denis, L.J.2
Rowinsky, E.K.3
Debono, J.S.4
Goetz, A.D.5
Ochoa, L.6
Forouzesh, B.7
Beeram, M.8
Patnaik, A.9
Molpus, K.10
Semiond, D.11
Besenval, M.12
Tolcher, A.W.13
-
47
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I, Gravis G, Bodrogi I, Mackenzie MJ, Shen L, Roessner M, Gupta S, Sartor AO,. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial. Lancet 2010; 376: 1147-1154.
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
MacHiels, J.P.5
Kocak, I.6
Gravis, G.7
Bodrogi, I.8
MacKenzie, M.J.9
Shen, L.10
Roessner, M.11
Gupta, S.12
Sartor, A.O.13
-
49
-
-
34347244905
-
Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study
-
DOI 10.1016/S1470-2045(07)70147-X, PII S147020450770147X
-
Nilsson S, Franzen L, Parker C, Tyrrell C, Blom R, Tennvall J, Lennernas B, Petersson U, Johannessen DC, Sokal M, Pigott K, Yachnin J, Garkavij M, Strang P, Harmenberg J, Bolstad B, Bruland OS,. Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study. Lancet Oncol 2007; 8: 587-594. (Pubitemid 46995621)
-
(2007)
Lancet Oncology
, vol.8
, Issue.7
, pp. 587-594
-
-
Nilsson, S.1
Franzen, L.2
Parker, C.3
Tyrrell, C.4
Blom, R.5
Tennvall, J.6
Lennernas, B.7
Petersson, U.8
Johannessen, D.C.9
Sokal, M.10
Pigott, K.11
Yachnin, J.12
Garkavij, M.13
Strang, P.14
Harmenberg, J.15
Bolstad, B.16
Bruland, O.S.17
-
50
-
-
84855666342
-
Radium-223 chloride, a first-in-class alpha-pharmaceutical with a benign safety profile for patients with castration resistant prostate cancer (CRPC) and bone metastases: Combined analysis of phase i and II clinical trials [abstract]
-
Abstract 4678.
-
Nilsson S, Parker C, Haugen I, Lokna A, Aksnes A, Bolstad B, O'Bryan-Tear G, Bruland OS,. Radium-223 chloride, a first-in-class alpha-pharmaceutical with a benign safety profile for patients with castration resistant prostate cancer (CRPC) and bone metastases: Combined analysis of phase I and II clinical trials [abstract]. J Clin Oncol 2010; 28: Abstract 4678.
-
(2010)
J Clin Oncol
, vol.28
-
-
Nilsson, S.1
Parker, C.2
Haugen, I.3
Lokna, A.4
Aksnes, A.5
Bolstad, B.6
O'Bryan-Tear, G.7
Bruland, O.S.8
-
51
-
-
0038514138
-
Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer
-
DOI 10.1200/JCO.2003.06.100
-
Halabi S, Small EJ, Kantoff PW, Kattan MW, Kaplan EB, Dawson NA, Levine EG, Blumenstein BA, Vogelzang NJ,. Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer. J Clin Oncol 2003; 21: 1232-1237. (Pubitemid 46606398)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.7
, pp. 1232-1237
-
-
Halabi, S.1
Small, E.J.2
Kantoff, P.W.3
Kattan, M.W.4
Kaplan, E.B.5
Dawson, N.A.6
Levine, E.G.7
Blumenstein, B.A.8
Vogelzang, N.J.9
|