Effects of leptin on the expression of fatty acid-binding proteins in human placental cell cultures

Molecular Medicine Reports

Volumn 5, Issue 2, 2012, Pages 497-502

  Mousiolis, Athanasios V ^a   Kollia, Panagoula ^a   Skentou, Chara ^a   Messinis, Ioannis E ^a  

^a UNIVERSITY OF THESSALY   (Greece)

Author keywords

FAT CD36; H FABP; Human placenta; L FABP; Leptin

Indexed keywords

FATTY ACID BINDING PROTEIN; LEPTIN; MEMBRANE PROTEIN; RNA;

ARTICLE; CHORION VILLUS SAMPLING; CYTOTROPHOBLAST; DRUG EFFECT; FATTY ACID METABOLISM; GESTATIONAL AGE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; NUCLEOTIDE SEQUENCE; PLACENTA; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SUPERNATANT; TROPHOBLAST; WESTERN BLOTTING;

ANTIGENS, CD36; CELLS, CULTURED; FATTY ACID-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LEPTIN; LIPID METABOLISM; PLACENTA; PREGNANCY;

EID: 84855667028     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.686     Document Type: Article

References (18)

1. Hamilton JA and Kamp F: How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids? Diabetes 48: 2255-2269, 1999. (Pubitemid 30395415)
2. Schaffer JE: Fatty acid transport: the roads taken. Am J Physiol Endocrinol Metab 282: E239-E246, 2002.
3. Haggarty P: Placental regulation of fatty acid delivery and its effect on fetal growth - a review. Placenta 23 (Suppl A): 28-38, 2002.
4. Bonen A, Luiken JJ, Arumugam Y, Glatz JF and Tandon NN: Acute regulation of fatty acid uptake involves the cellular redistribution of fatty acid translocase. J Biol Chem 275: 14501.14508, 2000.
5. Steinberg GR, Dyck DJ, Calles-Escandon J, et al: Chronic leptin administration decreases fatty acid uptake and fatty acid transporters in rat skeletal muscle. J Biol Chem 277: 8854-8860, 2002. (Pubitemid 34952953)
6. Guilbert LJ, Winkler-Lowen B, Sherburne R, Rote NS, Li H and Morrish DW: Preparation and functional characterization of villous cytotrophoblasts free of syncytial fragments. Placenta 23: 175-183, 2002. (Pubitemid 41110517)
7. Glatz JF and van der Vusse GJ: Cellular fatty acid-binding proteins: their function and physiological significance. Prog Lipid Res 35: 243-282, 1996. (Pubitemid 27092444)
8. Glatz JF, Luiken JJ, van Nieuwenhoven FA and van der Vusse GJ: Molecular mechanism of cellular uptake and intracellular translocation of fatty acids. Prostaglandins Leukot Essent Fatty Acids 57: 3-9, 1997. (Pubitemid 27300211)
9. Glatz JF, van Nieuwenhoven FA, Luiken JJ, Schaap FG and van der Vusse GJ: Role of membrane-associated and cytoplasmic fatty acid-binding proteins in cellular fatty acid metabolism. Prostaglandins Leukot Essent Fatty Acids 57: 373-378, 1997. (Pubitemid 27504728)
10. Campbell FM, Bush PG, Veerkamp JH and Dutta-Roy AK: Detection and cellular localization of plasma membrane-associated and cytoplasmic fatty acid-binding proteins in human placenta. Placenta 19: 409-415, 1998. (Pubitemid 28327700)
11. Chabowski A, Coort SL, Calles-Escandon J, et al: Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm. Am J Physiol Endocrinol Metab 287: E781-E789, 2004. (Pubitemid 39237909)
12. Glatz JF, Bonen A and Luiken JJ: Exercise and insulin increase muscle fatty acid uptake by recruiting putative fatty acid transporters to the sarcolemma. Curr Opin Clin Nutr Metab Care 5: 365-370, 2002. (Pubitemid 40684656)
13. Ibrahimi A, Bonen A, Blinn WD, et al: Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem 274: 26761-26766, 1999.
14. Zhang J, Phillips DI, Wang C and Byrne CD: Human skeletal muscle PPARalpha expression correlates with fat metabolism gene expression but not BMI or insulin sensitivity. Am J Physiol Endocrinol Metab 286: E168-E175, 2004. (Pubitemid 38140306)
15. Bonen A, Benton CR, Campbell SE, et al: Plasmalemmal fatty acid transport is regulated in heart and skeletal muscle by contraction, insulin and leptin, and in obesity and diabetes. Acta Physiol Scand 178: 347-356, 2003. (Pubitemid 36960425)
16. Abumrad N, Coburn C and Ibrahimi A: Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochim Biophys Acta 1441: 4-13, 1999. (Pubitemid 29469432)
17. Spitsberg VL, Matitashvili E and Gorewit RC: Association and coexpression of fatty-acid-binding protein and glycoprotein CD36 in the bovine mammary gland. Eur J Biochem 230: 872-878, 1995.
18. Das T, Sa G and Mukherjea M: Characterization of cardiac fatty-acid-binding protein from human placenta. Comparison with placenta hepatic types. Eur J Biochem 211: 725-730, 1993. (Pubitemid 23050046)