Efficacy of hydrosurgical debridement and nanocrystalline silver dressings for infection prevention in type II and III open injuries

International Wound Journal

Volumn 9, Issue 1, 2012, Pages 7-13

  Keen, Jeffrey S ^a   Desai, Pratik P ^a   Smith, Christopher S ^a   Suk, Michael ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b GEISINGER HEALTH SYSTEM   (United States)

Author keywords

Hydrosurgical debridement; Open fractures; Silver dressings

Indexed keywords

ANTIBIOTIC AGENT; CEFALEXIN; GENTAMICIN; NANOCRYSTALLINE SILVER; SILVER DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DEBRIDEMENT; EMERGENCY WARD; FEMALE; FRACTURE FIXATION; HUMAN; INFECTION RATE; INJURY SEVERITY; LENGTH OF STAY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; OPEN FRACTURE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCALPEL; SCHOOL CHILD; SCORING SYSTEM; SURGICAL TECHNIQUE; TISSUE CULTURE; TREATMENT OUTCOME; WOUND DRESSING; WOUND HEALING; WOUND INFECTION; WOUND IRRIGATION;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; BANDAGES; CHILD; DEBRIDEMENT; FEMALE; FOLLOW-UP STUDIES; FRACTURES, OPEN; HUMANS; MALE; METAL NANOPARTICLES; MIDDLE AGED; PRESSURE; RETROSPECTIVE STUDIES; SILVER; TREATMENT OUTCOME; WATER; WOUND HEALING; WOUND INFECTION; YOUNG ADULT;

EID: 84855616250     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/j.1742-481X.2011.00822.x     Document Type: Article

References (33)

1. Olson SA, Schemitsch EH. Open fractures of the tibial shaft: an update. Instr Course Lect 2003;52:623-31.
2. Gosselin RA, Roberts I, Gillespie WJ. Antibiotics for preventing infection in open limb fractures. Cochrane Database Syst Rev 2004;CD003764.
3. Papachristou DN, Barters R. Resection of the liver with a water jet. Br J Surg 1982;69:93-4.
4. Terzis AJ, Nowak G, Rentzsch O, Arnold H, Diebold J, Baretton, G. A new system for cutting brain tissue preserving vessels: water jet cutting. Br J Neurosurg 1989;3:361-6.
5. Oertel J, Gaab MR, Knapp A, Essig H, Warzok R, Piek J. Water jet dissection in neurosurgery: experimental results in the porcine cadaveric brain. Neurosurgery 2003;52:153-9.
6. Brett DW. A discussion of silver as an antimicrobial agent: alleviating the confusion. Ostomy Wound Manage 2006;52:34-41.
7. Wright JB, Hansen DL, Burrell RE. The comparative efficacy of two antimicrobial barrier dressings. Wounds 1998;10:179-88.
8. Poon VK, Burd A. In vitro cytotoxity of silver: implication for clinical wound care. Burns 2004;30:140-7.
9. Fraser JF, Cuttle L, Kempf M, Kimble RM. Cytotoxicity of topical antimicrobial agents used in burn wounds in Australasia. ANZ J Surg 2004;74:139-42.
10. Supp AP, Neely AN, Supp DM, Warden GD, Boyce ST. Evaluation of cytotoxicity and antimicrobial activity of Acticoat burn dressing for management of microbial contamination in cultured skin substitutes grafted to athymic mice. J Burn Care Rehabil 2005;26:238-46.
11. Dunn K, Edwards-Jones V. The role of Acticoat with nanocrystalline silver in the management of burns. Burns 2004;30(1 Suppl):S1-9.
12. Tredget EE, Shankowsky HA, Groeneveld A, Burrell R. A matched-pair, randomized study evaluating the efficacy and safety of Acticoat silver-coated dressing for the treatment of burn wounds. J Burn Care Rehabil 1998;19: 531-7.
13. Wright JB, Lam K, Burrell RE. Wound management in an era of increasing bacterial antibiotic resistance: a role for topical silver treatment. Am J Infect Control 1998;26:572-7.
14. Demling RH, DeSanti L. Effects of silver on wound management. Wounds 2001;13 Suppl A:4.
15. Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg Am 1976;58:453-8.
16. Gustilo RB, Mendoza RM, Williams DN. Problems in the management of type III (severe) open fractures: a new classification of type III open fractures. J Trauma 1984;24:742-46.
17. Green SA, Moore TA, Spohn PJ. Nonunion of the tibial shaft. Orthopaedics 1988;11:1149-57.
18. Brueckmann FR, Roberts GJ. Complications of open tibial fractures. Indiana Med 1989;82:694-8.
19. Malik MH, Harwood P, Diggle P, Khan SA. Factors affecting rate of infection and nonunion in intramedullary nailing. J Bone Joint Surg Br 2004;86:556-60.
20. Karladani AH, Granhed H, Karrholm J, Styf J. The influence of fracture etiology and type on fracture healing: a review of 104 consecutive tibial shaft fractures. Arch Orthop Trauma Surg 2001;121:325-8.
21. Esterhai JL, Queenan J. Management of soft tissue wounds associated with type III open fractures. Orthop Clin North Am 1991;22:427-32.
22. Fischer MD, Gustilo RB, Varecka TF. The timing of flap coverage, bone-grafting, and intramedullary nailing in patients who have a fracture of the tibial shaft with extensive soft-tissue injury. J Bone Joint Surg Am 1991;73:1316-22.
23. Lenarz CJ, Watson T, Moed BR, Israel H, Mullen JD, MacDonald JB. Timing of wound closure in open fractures based on cultures obtained after debridement. J Bone Joint Surg 2010;92:1921-6.
24. Adili A, Bhandari M, Schemitsch EH. The biomechanical effect of high-pressure irrigation on diaphyseal fracture healing in vivo. J Orthop Trauma 2002;16:413-7.
25. Boyd JI III, Wongworawat MD. High-pressure pulsatile lavage causes soft tissue damage. Clin Orthop Relat Res 2004;427:13-7.
26. Park SH, Silva M, Bahk WJ, McKellop H, Lieberman JR. Effect of repeated irrigation and debridement on fracture healing in an animal model. J Orthop Res 2002;20:1197-204.
27. Petrisor B, Jeray K, Schemitsch E, Hanson B, Sprague S, Sanders D, Bhandari M, FLOW Investigators. Fluid lavage in patients with open fracture wounds (FLOW): an international survey of 984 surgeons. BMC Muskuloskelet Disord 2008;9:7.
28. Webb LX, Pape H. Current thought regarding the mechanism of action of negative pressure wound therapy with reticulated open cell foam. J Orthop Trauma 2008;22:135-7.
29. Stannard JP, Volgas DA, Stewart R, McGwin G Jr, Alonso JE. Negative pressure wound therapy after severe open fractures: a prospective randomized study. J Orthop Trauma 2009;23:552-7.
30. Schlatterer D, Hirshorn K. Negative pressure wound therapy with reticulated open cell foam-adjunctive treatment in the management of traumatic wounds of the leg: a review of the literature. J Orthop Trauma 2008;22:152-60.
31. Storm-Versloot MN, Vos CG, Ubbink DT, Vermeulen H. Topical silver for preventive wound infection. Cochrane Database Syst Rev 2010;CD006478. doi:10.1002/14651858. CD006478.pub2.
32. Patzakis MJ, Wilkins J. Factors influencing infection rate in open fracture wounds. Clin Orthop Relat Res 1989;243:36-40.
33. Gustilo RB, Gruninger RP, Davis T. Classification of type III (severe) open fractures relative to treatment and results. Orthopedics 1987;10:1781-8.