Supplementation of vitamin C reduces blood glucose and improves glycosylated hemoglobin in type 2 diabetes mellitus: A randomized, double-blind study

Advances in Pharmacological Sciences

Volumn 2011, Issue , 2011, Pages

  Dakhale, Ganesh N ^a   Chaudhari, Harshal V ^a   Shrivastava, Meena ^b  

^a GOVERNMENT MEDICAL COLLEGE   (India)

^b Shri Sathya Sai Medical College and Research Institute   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; GLUCOSE; HEMOGLOBIN A1C; METFORMIN; PLACEBO;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEMOGLOBIN DETERMINATION; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

EID: 84855593860     PISSN: 16876334     EISSN: 16876342     Source Type: Journal    
DOI: 10.1155/2011/195271     Document Type: Article

References (23)

1. Mesallamy H. E., Suwailem S., Hamdy N., Evaluation of C-reactive protein, endothelin-1, adhesion molecule(s), and lipids as inflammatory markers in type 2 diabetes mellitus patients Mediators of Inflammation 2007 2007 7
2. Alamdari D. H., Paletas K., Pegiou T., Sarigianni M., Befani C., Koliakos G. A., A novel assay for the evaluation of the prooxidant-antioxidant balance, before and after antioxidant vitamin administration in type II diabetes patients Clinical Biochemistry 2007 40 3-4 248 254 (Pubitemid 46108709)
3. Gupta M., Chari S., Proxidant and antioxidant status in patients of type II diabetes mellitus with IHD Indian Journal of Clinical Biochemistry 2006 21 2 118 122 (Pubitemid 44756936)
4. Bianchi C., Miccoli R., Daniele G., Penno G., Del Prato S., Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity/mortality? yes Diabetes care 2009 32 2 342 348
5. Fadupin G. T., Akpoghor A. U., Okunade K. A., A comparative study of serum ascorbic acid level in people with and without type 2 diabetes in Ibadan, Nigeria African Journal of Medicine and Medical Sciences 2007 36 4 335 339
6. Ardekani M. A., Ardekani A. S., Effect of vitamin C on blood glucose, serum lipids serum insulin in type II diabetes patients Indian Journal of Medical Research 2007 126 5 471 474
7. Sargeant L. A., Wareham N. J., Bingham S., Day N. E., Luben R. N., Oakes S., Welch A., Khaw K. T., Vitamin C and hyperglycemia in the European prospective investigation into cancerNorfolk (EPIC-Norfolk) study: a population based study Diabetes Care 2000 23 6 726 732 (Pubitemid 30414183)
8. Bishop N., Schorah C. J., Wales J. K., The effect of vitamin C supplementation on diabetic hyperlipidaemia: a double blind, crossover study Diabetic Medicine 1995 2 2 121 124
9. Kyaw A., A simple colorimetric method for ascorbic acid determination in blood plasma Clinica Chimica Acta 1978 86 2 153 157 (Pubitemid 8349344)
10. Sridulyakul P., Chakraphan D., Patumraj S., Vitamin C supplementation could reverse diabetes-induced endothelial cell dysfunction in mesenteric microcirculation in STZ-rats Clinical Hemorheology and Microcirculation 2006 34 1-2 315 321 (Pubitemid 43351045)
11. Ardekani M. A., Mohiti J., Amirchaghmaghi E., Modarresi M., The effect of vitamin C supplementation on insulin level, HbA1c and blood glucose in type 2 diabetic patients Journal of Kerman University of Medical Sciences 2006 11 12 18
12. Bonnefont R. D., Bastard J. P., Jaudon M. C., Delattre J., Consequences of the diabetic status on the oxidant/antioxidant balance Diabetes and Metabolism 2000 26 3 163 176 (Pubitemid 30435761)
13. Ceriello A., Bortolotti N., Crescentini A., Motz E., Lizzio S., Russo A., zsol Z., Tonutti L., Taboga C., Antioxidant defences are reduced during the oral glucose tolerance test in normal and non-insulin-dependent diabetic subjects European Journal of Clinical Investigation 1998 28 4 329 333 (Pubitemid 28188309)
14. Hirsch I. B., Atchley D. H., Tsai E., Labbé R. F., Chait A., Ascorbic acid clearance in diabetic nephropathy Journal of Diabetes and its Complications 1998 12 5 259 263 (Pubitemid 28423396)
15. Vincent T. E., Mendiratta S., May J. M., Inhibition of aldose reductase in human erythrocytes by vitamin C Diabetes Research and Clinical Practice 1998 43 1 1 8
16. Srivatsan R., Das S., Gadde R., Manoj-Kumar K., Taduri S., Rao N., Ramesh B., Baharani A., Shah K., Kamireddy S. C., Priyatham G., Balakumaran T. A., Seshadri S., Kamath A., Rao A., Antioxidants and lipid peroxidation status in diabetic patients with and without complications Archives of Iranian Medicine 2009 12 2 121 127
17. Eriksson J., Kohvakka A., Magnesium and ascorbic acid supplementation in diabetes mellitus Annals of Nutrition and Metabolism 1995 39 4 217 223
18. Eriksson J., Kohvakka A., Kagan V. E., Melhem M., Studer R. K., Effects of supplementation with vitamin C or E on albuminuria, glomerular IGF- and glomerular size in diabetics Journal of the American Society of Nephrology 1997 89 9 1405 1414
19. Sridulyakul P., Chakraphan D., Patumraj S., Vitamin C supplementation could reverse diabetes-induced endothelial cell dysfunction in mesenteric microcirculation in STZ-rats Clinical Hemorheology and Microcirculation 2006 34 1-2 315 321 (Pubitemid 43351045)
20. Davie S. J., Gould B. J., Yudkin J. S., Effect of vitamin C on glycosylation of proteins Diabetes 1992 41 2 167 173
21. Szaleczky E., Prechl J., Ruzicska E., Feher J., Braun L., Banhegyi G., Csala M., Mandi J., Somogyi A., Reduction of glycated hemoglobin levels by long term, high dose ascorbic acid supplementation in healthy and diabetic patients Medical Science Monitor 1998 4 2 241 244 (Pubitemid 28216009)
22. Jukka M., Paul K., Ritva J., Antti R., Dietary antioxidant intake and risk of type 2 diabetes Diabetes Care 2004 27 2 362 366
23. Sébastien C., Aline C., Sandrine B., Anne-Claire V., Luc D., Serge H., Hercberg S., Antioxidant supplementation does not affect fasting plasma glucose in the supplementation with antioxidant vitamins and minerals (SU.VI.MAX) study in France: association with dietary intake and plasma concentrations American Journal of Clinical Nutrition 2006 84 2 395 399 (Pubitemid 44699151)