Genetic diversity of Ascaris in southwestern Uganda

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 106, Issue 2, 2012, Pages 75-83

  Betson, Martha ^a   Nejsum, Peter ^b   Llewellyn Hughes, Julia ^c   Griffin, Claire ^c   Atuhaire, Aaron ^d   Arinaitwe, Moses ^d   Adriko, Moses ^d   Ruggiana, Andrew ^d   Turyakira, Grace ^e   Kabatereine, Narcis B ^d   Stothard, J Russell ^a  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c DEPARTMENT OF LIFE SCIENCES   (United Kingdom)

^d MINISTRY OF HEALTH   (Uganda)

^e Vector Control Division   (Uganda)

Author keywords

Ascaris; Cytochrome c oxidase subunit 1; Evolution; Microsatellite; Population genetics; Uganda

Indexed keywords

ALBENDAZOLE; CYTOCHROME C OXIDASE; GENOMIC DNA; MICROSATELLITE DNA; PRAZIQUANTEL; PYRANTEL EMBONATE;

ADULT; AMPLIFIED FRAGMENT LENGTH POLYMORPHISM; ANEMIA; ARTICLE; ASCARIASIS; ASCARIS; ASCARIS LUMBRICOIDES; CHILD; DNA EXTRACTION; DNA SEQUENCE; FECES CULTURE; GENE LOCUS; GENE REGULATORY NETWORK; GENETIC ANALYSIS; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INFECTION CONTROL; MAJOR CLINICAL STUDY; MALARIA; MICROSATELLITE MARKER; MORBIDITY; PARASITE IDENTIFICATION; PREVALENCE; PUBLIC HEALTH PROBLEM; SCHISTOSOMA MANSONI; SEQUENCE ANALYSIS; TRICHURIASIS; UGANDA; URINALYSIS;

ADOLESCENT; ADULT; ANIMALS; ASCARIASIS; ASCARIS; CHILD; CHILD, PRESCHOOL; CYCLOOXYGENASE 1; DNA, HELMINTH; FEMALE; HUMANS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MOLECULAR EPIDEMIOLOGY; MOLECULAR SEQUENCE DATA; MOTHERS; POLYMORPHISM, GENETIC; UGANDA; YOUNG ADULT;

ASCARIS; VERMES;

EID: 84855562516     PISSN: 00359203     EISSN: 18783503     Source Type: Journal    
DOI: 10.1016/j.trstmh.2011.10.011     Document Type: Article

References (34)

1. de Silva N.R., Brooker S., Hotez P.J., Montresor A., Engels D., Savioli L. Soil-transmitted helminth infections: updating the global picture. Trends Parasitol 2003, 19:547-551.
2. WHO. Neglected tropical diseases. Diseases covered by NTD Department. Geneva: World Health Organization; ©2011. [accessed 7 June 2011]. http://www.who.int/neglected_diseases/diseases/en/.
3. WHO Preventative chemotherapy in human helminthiasis 2006, World Health Organization, Geneva.
4. Brooker S., Kabatereine N.B., Tukahebwa E.M., Kazibwe F. Spatial analysis of the distribution of intestinal nematode infections in Uganda. Epidemiol Infect 2004, 132:1065-1071.
5. Kabatereine N.B., Tukahebwa E.M., Kazibwe F., Twa-Twa J.M., Barenzi J.F., Zaramba S., et al. Soil-transmitted helminthiasis in Uganda: epidemiology and cost of control. Trop Med Int Health 2005, 10:1187-1189.
6. Uganda Districts Information Handbook. 2nd ed. Kampala: Fountain Publishers; 2007.
7. Fleming F.M., Fenwick A., Tukahebwa E.M., Lubanga R.G., Namwangye H., Zaramba S., et al. Process evaluation of schistosomiasis control in Uganda, 2003 to 2006: perceptions, attitudes and constraints of a national programme. Parasitology 2009, 136:1759-1769.
8. Kabatereine N.B., Brooker S., Tukahebwa E.M., Kazibwe F., Onapa A.W. Epidemiology and geography of Schistosoma mansoni in Uganda: implications for planning control. Trop Med Int Health 2004, 9:372-380.
9. Kabatereine N.B., Fleming F.M., Nyandindi U., Mwanza J.C., Blair L. The control of schistosomiasis and soil-transmitted helminths in East Africa. Trends Parasitol 2006, 22:332-339.
10. Kolaczinski J.H., Kabatereine N.B., Onapa A.W., Ndyomugyenyi R., Kakembo A.S., Brooker S. Neglected tropical diseases in Uganda: the prospect and challenge of integrated control. Trends Parasitol 2007, 23:485-493.
11. Stothard J.R., Pleasant J., Oguttu D., Adriko M., Galimaka R., Ruggiana A., et al. Strongyloides stercoralis: a field-based survey of mothers and their preschool children using ELISA, Baermann and Koga plate methods reveals low endemicity in western Uganda. J Helminthol 2008, 82:263-269.
12. Anderson T.J. Ascaris infections in humans from North America: molecular evidence for cross-infection. Parasitology 1995, 110(Pt 2):215-219.
13. Nejsum P., Parker E.D., Frydenberg J., Roepstorff A., Boes J., Haque R., et al. Ascariasis is a zoonosis in Denmark. J Clin Microbiol 2005, 43:1142-1148.
14. Anderson T.J. The dangers of using single locus markers in parasite epidemiology: Ascaris as a case study. Trends Parasitol 2001, 17:183-188.
15. Criscione C.D., Anderson J.D., Sudimack D., Subedi J., Upadhayay R.P., Jha B., et al. Landscape genetics reveals focal transmission of a human macroparasite. PLoS Negl Trop Dis 2010, 4:e665.
16. Peng W., Yuan K., Hu M., Zhou X., Gasser R.B. Mutation scanning-coupled analysis of haplotypic variability in mitochondrial DNA regions reveals low gene flow between human and porcine Ascaris in endemic regions of China. Electrophoresis 2005, 26:4317-4326.
17. Peng W., Yuan K., Zhou X., Hu M., Abs ELOYG, Gasser R.B. Molecular epidemiological investigation of Ascaris genotypes in China based on single-strand conformation polymorphism analysis of ribosomal DNA. Electrophoresis 2003, 24:2308-2315.
18. Zhou C., Li M., Yuan K., Hu N., Peng W. Phylogeography of Ascaris lumbricoides and A. suum from China. Parasitol Res 2011, 109:329-338.
19. Betson M., Halstead F.D., Nejsum P., Imison E., Khamis I.S., Sousa-Figueiredo J.C., et al. A molecular epidemiological investigation of Ascaris on Unguja, Zanzibar using isoenyzme analysis, DNA barcoding and microsatellite DNA profiling. Trans R Soc Trop Med Hyg 2011, 105:370-379.
20. Knopp S., Mohammed K.A., Stothard J.R., Khamis I.S., Rollinson D., Marti H., et al. Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs. PLoS Negl Trop Dis 2010, 4:e681.
21. Olsen A., Namwanje H., Nejsum P., Roepstorff A., Thamsborg S.M. Albendazole and mebendazole have low efficacy against Trichuris trichiura in school-age children in Kabale District, Uganda. Trans R Soc Trop Med Hyg 2009, 103:443-446.
22. Katz N., Chaves A., Pellegrino J. A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo 1972, 14:397-400.
23. Montresor A., Crompton D.W.T., Hall A., Bundy D.A., Savioli L. Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level 1998, World Health Organization, Geneva.
24. Criscione C.D., Anderson J.D., Raby K., Sudimack D., Subedi J., Rai D.R., et al. Microsatellite markers for the human nematode parasite Ascaris lumbricoides: development and assessment of utility. J Parasitol 2007, 93:704-708.
25. Excoffier L., Laval G., Schneider S. Arlequin (version 3.0): an integrated software package for population genetics data analysis. Evol Bioinform Online 2005, 1:47-50.
26. Raymond M., Rousset F. GENEPOP (version 1.2): population software for exact tests and ecumenism. J Heredity 1995, 86:248-249.
27. Goudet J. FSTAT: A program to calculate F-statistics, version 1.2. J Heredity 1995, 86:485-486.
28. Weir B.S., Cockerham C.C. Estimating F-statistics for the analysis of population structure. Evolution 1984, 38:1358-1370.
29. Meirmans P.G. Using the AMOVA framework to estimate a standardized genetic differentiation measure. Evolution 2006, 60:2399-2402.
30. Pritchard J.K., Stephens M., Donnelly P. Inference of population structure using multilocus genotype data. Genetics 2000, 155:945-959.
31. Hubisz M.J., Falush D., Stephens M., Pritchard J.K. Inferring weak population structure with the assistance of sample group information. Mol Ecol Resour 2009, 9:1322-1332.
32. Nissen S., Poulsen I.H., Nejsum P., Olsen A., Roepstorff A., Rubaire-Akiiki C., et al. Prevalence of gastrointestinal nematodes in growing pigs in Kabale District in Uganda. Trop Anim Health Prod 2011, 43:567-572.
33. Criscione C.D., Anderson J.D., Sudimack D., Peng W., Jha B., Williams-Blangero S., et al. Disentangling hybridization and host colonization in parasitic roundworms of humans and pigs. Proc Biol Sci 2007, 274:2669-2677.
34. Anderson T.J., Jaenike J. Host specificity, evolutionary relationships and macrogeographic differentiation among Ascaris populations from humans and pigs. Parasitology 1997, 115(Pt 3):325-342.