Improved proteomic approach for the discovery of potential vaccine targets in Trypanosoma cruzi

Journal of Proteome Research

Volumn 11, Issue 1, 2012, Pages 237-246

  Nakayasu, Ernesto S ^a,c   Sobreira, Tiago J P ^b   Torres, Rafael ^a   Ganiko, Luciane ^a   Oliveira, Paulo S L ^b   Marques, Alexandre F ^a   Almeida, Igor C ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

^b BRAZILIAN CENTER FOR RESEARCH IN ENERGY AND MATERIALS CNPEM   (Brazil)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Chagas disease; epitope prediction; immunoinformatics; proteomic analysis; Trypanosoma cruzi; trypomastigote stage; vaccine development

Indexed keywords

BALANCED SALT SOLUTION; EPITOPE; GLYCOSYLPHOSPHATIDYLINOSITOL; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOINFORMATICS; CELL INVASION; CHAGAS DISEASE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOST CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEOMICS; SEPARATION TECHNIQUE; T LYMPHOCYTE; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ANIMALS; ANTIGENS, PROTOZOAN; CELL LINE; CERCOPITHECUS AETHIOPS; CHAGAS DISEASE; CHROMATOGRAPHY, REVERSE-PHASE; COMPUTER SIMULATION; EPITOPE MAPPING; EPITOPES, B-LYMPHOCYTE; GPI-LINKED PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; PEPTIDE FRAGMENTS; PROTEOME; PROTEOMICS; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; TANDEM MASS SPECTROMETRY; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 84855558173     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200806s     Document Type: Article

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