A review of rifaximin and bacterial overgrowth in poorly responsive celiac disease

Therapeutic Advances in Gastroenterology

Volumn 5, Issue 1, 2012, Pages 31-36

  Chang, Matthew S ^a   Green, Peter H R ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

Breath tests; Gluten free diet; Questionnaires; Small intestine

Indexed keywords

LACTULOSE; PLACEBO; RIFAXIMIN;

BACTERIAL OVERGROWTH; CELIAC DISEASE; GASTROINTESTINAL SYMPTOM; GLUTEN FREE DIET; HUMAN; HYDROGEN BREATH TEST; PRIORITY JOURNAL; REVIEW; SCORING SYSTEM;

EID: 84855556361     PISSN: 1756283X     EISSN: 17562648     Source Type: Journal    
DOI: 10.1177/1756283X11422264     Document Type: Review

References (42)

1. Abdallah H. Leffler D. Dennis M. Kelly C. (2007) Refractory celiac disease. Curr Gastroenterol Rep 9: 401–405.
2. Abdulkarim A.S. Burgart L.J. See J. Murray J.A. (2002) Etiology of nonresponsive celiac disease: results of a systematic approach. Am J Gastroenterol 97: 2016–2021.
3. Bassotti G. Villanacci V. Mazzocchi A. Mariano M. Incardona P. Clerici C. et al. (2008) Antroduodenojejunal motor activity in untreated and treated celiac disease patients. J Gastroenterol Hepatol 23(7 Part 2): e23–e28.
4. Cellier C. Delabesse E. Helmer C. Patey N. Matuchansky C. Jabri B. et al. (2000) Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. French Coeliac Disease Study Group. Lancet 356: 203–208.
5. Chang M.S. Minaya M.T. Cheng J. Connor B.A. Lewis S.K. Green P.H. (2011) Double-blind randomized controlled trial of rifaximin for persistent symptoms in patients with celiac disease. Dig Dis Sci (in press).
6. Chiarioni G. Bassotti G. Germani U. Battaglia E. Brentegani M.T. Morelli A. et al. (1997) Gluten-free diet normalizes mouth-to-cecum transit of a caloric meal in adult patients with celiac disease. Dig Dis Sci 42: 2100–2105.
7. Corazza G. Menozzi M. Strocchi A. Rasciti L. Vaira D. Lecchini R. et al. (1990) The diagnosis of small bowel bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing. Gastroenterology 98: 302–309.
8. Corazza G.R. Strocchi A. Gasbarrini G. (1987) Fasting breath hydrogen in celiac disease. Gastroenterology 93: 53–58.
9. Daum S. Cellier C. Mulder C.J. (2005) Refractory coeliac disease. Best Pract Res Clin Gastroenterol 19: 413–424.
10. Fan X. Sellin J.H. (2009) Review article: Small intestinal bacterial overgrowth, bile acid malabsorption and gluten intolerance as possible causes of chronic watery diarrhoea. Aliment Pharmacol Ther 29: 1069–1077.
11. Fine K.D. Meyer R.L. Lee E.L. (1997) The prevalence and causes of chronic diarrhea in patients with celiac sprue treated with a gluten-free diet. Gastroenterology 112: 1830–1838.
12. Ford A.C. Spiegel B.M. Talley N.J. Moayyedi P. (2009) Small intestinal bacterial overgrowth in irritable bowel syndrome: systematic review and meta-analysis. Clin Gastroenterol Hepatol 7: 1279–1286.
13. Fraquelli M. Colli A. Colucci A. Bardella M.T. Trovato C. Pometta R. et al. (2004) Accuracy of ultrasonography in predicting celiac disease. Arch Intern Med 164: 169–174.
14. Gasbarrini A. Corazza G.R. Gasbarrini G. Montalto M. Di Stefano M. Basilisco G. et al. (2009) Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference. Aliment Pharmacol Ther 29(Suppl. 1): 1–49.
15. Ghoshal U. Ghoshal U. Misra A. Choudhuri G. (2004) Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance. BMC Gastroenterol 4: 10.
16. Gonda T.A. Khan S.U. Cheng J. Lewis S.K. Rubin M. Green P.H. (2010) Association of intussusception and celiac disease in adults. Dig Dis Sci 55: 2899–2903.
17. Green P. Cellier C. (2007) Celiac disease. N Engl J Med 357: 1731–1743.
18. Khoshini R. Dai S.C. Lezcano S. Pimentel M. (2008) A systematic review of diagnostic tests for small intestinal bacterial overgrowth. Dig Dis Sci 53: 1443–1454.
19. Lauritano E. Gabrielli M. Lupascu A. Santoliquido A. Nucera G. Scarpellini E. et al. (2005) Rifaximin dose-finding study for the treatment of small intestinal bacterial overgrowth. Aliment Pharmacol Ther 22: 31–35.
20. Leffler D.A. Dennis M. Hyett B. Kelly E. Schuppan D. Kelly C.P. (2007) Etiologies and predictors of diagnosis in nonresponsive celiac disease. Clin Gastroenterol Hepatol 5: 445–450.
21. Midhagen G. Hallert C. (2003) High rate of gastrointestinal symptoms in celiac patients living on a gluten-free diet: controlled study. Am J Gastroenterol 98: 2023–2026.
22. O'Mahony S. Howdle P. Losowsky M. (1996) Review article: management of patients with non-responsive coeliac disease. Aliment Pharmacol Ther 10: 671–680.
23. Pelosini I. Scarpignato C. (2005) Rifaximin, a peculiar rifamycin derivative: established and potential clinical use outside the gastrointestinal tract. Chemotherapy 51(Suppl. 1): 122–130.
24. Pimentel M. Chow E.J. Lin H.C. (2000) Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome. Am J Gastroenterol 95: 3503–3506.
25. Pimentel M. Chow E.J. Lin H.C. (2003) Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome. A double-blind, randomized, placebo-controlled study. Am J Gastroenterol 98: 412–419.
26. Prizont R. Hersh T. Floch M.H. (1970) Jejunal bacterial flora in chronic small bowel disease. I. Celiac disease. II. Regional enteritis. Am J Clin Nutr 23: 1602–1607.
27. Quigley E. Quera R. (2006) Small Intestinal Bacterial Overgrowth: Roles of Antibiotics, Prebiotics, and Probiotics. Gastroenterology 130: S78–S90.
28. Rana S. Bhardwaj S. (2008) Small intestinal bacterial overgrowth. Scand J Gastroenterol 43: 1030–1037.
29. Rana S.V. Sinha S.K. Lal S. Sikander A. Singh K. (2007) Small intestinal bacterial overgrowth in North Indian patients with celiac disease. Trop Gastroenterol 28: 159–161.
30. Rettenbacher T. Hollerweger A. Macheiner P. Huber S. Gritzmann N. (1999) Adult celiac disease: US signs. Radiology 211: 389–394.
31. Roufail W.M. Ruffin J.M. (1966) Effect of antibiotic therapy on gluten-sensitive enteropathy. Am J Dig Dis 11: 587–593.
32. Rubin C.E. Eidelman S. Weinstein W.M. (1970) Sprue by any other name. Gastroenterology 58: 409–413.
33. Rubio-Tapia A. Barton S.H. Rosenblatt J.E. Murray J.A. (2009) Prevalence of small intestine bacterial overgrowth diagnosed by quantitative culture of intestinal aspirate in celiac disease. J Clin Gastroenterol 43: 157–161.
34. Ryan B.M. Kelleher D. (2000) Refractory celiac disease. Gastroenterology 119 (1): 243–251.
35. Scarpellini E. Gabrielli M. Lauritano E. Lupascu A. Merra G. Cammarota G. et al. (2007) High dosage rifaximin for the treatment of small intestinal bacterial overgrowth. Aliment Pharmacol Ther 25: 781–786.
36. Sharara A.I. Aoun E. Abdul-Baki H. Mounzer R. Sidani S. Elhajj I. (2006) A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence. Am J Gastroenterol 101: 326–333.
37. Svedlund J. Sjodin I. Dotevall G. (1988) GSRS - a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci 33: 129–134.
38. Tomei E. Diacinti D. Marini M. Mastropasqua M. Di Tola M. Sabbatella L. et al. (2005) Abdominal CT findings may suggest coeliac disease. Dig Liver Dis 37: 402–406.
39. Trier J.S. Falchuk Z.M. Carey M.C. Schreiber D.S. (1978) Celiac sprue and refractory sprue. Gastroenterology 75: 307–316.
40. Tursi A. (2004) Gastrointestinal motility disturbances in celiac disease. J Clin Gastroenterol 38: 642–645.
41. Tursi A. Brandimarte G. Giorgetti G. (2003) High prevalence of small intestinal bacterial overgrowth in celiac patients with persistence of gastrointestinal symptoms after gluten withdrawal. Am J Gastroenterol 98: 839–843.
42. Walters B. Vanner S.J. (2005) Detection of bacterial overgrowth in IBS using the lactulose H 2 breath test: comparison with 14C-D-xylose and healthy controls. Am J Gastroenterol 100: 1566–1570.