Pathologic fractures in children with acute Staphylococcus aureus osteomyelitis

Journal of Bone and Joint Surgery

Volumn 94, Issue 1, 2012, Pages 34-42

  Belthur, Mohan V ^a   Birchansky, Sherri B ^b   Verdugo, Alejandro A ^b   Mason, Edward O ^b   Hulten, Kristina G ^b   Kaplan, Sheldon L ^b   Smith, E O'Brian ^b   Phillips, William A ^b   Weinberg, Jacob ^c  

^a SINAI HOSPITAL OF BALTIMORE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

^c Orthopaedic Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; METICILLIN;

ADOLESCENT; AGE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM ISOLATE; BONE MARROW; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; LONG BONE; MALE; MEDICAL RECORD REVIEW; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MICROBIOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOMYELITIS; PATHOLOGIC FRACTURE; PERIOSTEUM; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; SEX; STAPHYLOCOCCUS AUREUS; SURGICAL TECHNIQUE;

EID: 84855522618     PISSN: 00219355     EISSN: 15351386     Source Type: Journal    
DOI: 10.2106/JBJS.J.01915     Document Type: Article

References (42)

1. Copley LAB. Musculoskeletal infection in children. Curr Opin Orthop. 2005;16: 445-450. (Pubitemid 41682206)
2. Frank G, Mahoney HM, Eppes SC. Musculoskeletal infections in children. Pediatr Clin North Am. 2005;52:1083-106, ix. (Pubitemid 40961616)
3. Krogstad P. Osteomyelitis. In: Feigin RD, Cherry JD, Demmler GJ, Kaplan SL, editors. Feigin and Cherry's textbook of pediatric infectious diseases. 6th ed. Philadelphia: Saunders Elsevier; 2009. p 725-42.
4. McCarthy JJ, Dormans JP, Kozin SC, Pizzutillo P. Musculoskeletal infections in children: basic treatment principles and recent advancements. J Bone Joint Surg Am. 2004;86:850-63. (Pubitemid 38436733)
5. Nade S. Acute haematogenous osteomyelitis in infancy and childhood. J Bone Joint Surg Br. 1983;65:109-19. (Pubitemid 13114790)
6. Waldvogel FA, Medoff G, Swartz MN. Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects. N Engl J Med. 1970;282:198-206.
7. Browne LP, Mason EO, Kaplan SL, Cassady CI, Krishnamurthy R, Guillerman RP. Optimal imaging strategy for community-acquired Staphylococcus aureus musculoskeletal infections in children. Pediatr Radiol. 2008;38:841-7.
8. Copley LA. Pediatric musculoskeletal infection: trends and antibiotic recommendations. J Am Acad Orthop Surg. 2009;17:618-26.
9. Arnold SR, Elias D, Buckingham SC, Thomas ED, Novais E, Arkader A, Howard C. Changing patterns of acute hematogenous osteomyelitis and septic arthritis: emergence of community-associated methicillin-resistant Staphylococcus aureus. J Pediatr Orthop. 2006;6:703-8. (Pubitemid 44655534)
10. Gafur OA, Copley LA, Hollmig ST, Browne RH, Thornton LA, Crawford SE. The impact of the current epidemiology of pediatric musculoskeletal infection on evaluation and treatment guidelines. J Pediatr Orthop. 2008;28:777-85.
11. Gwynne-Jones DP, Stott NS. Community-acquired methicillin-resistant Staphylococcus aureus: a cause of musculoskeletal sepsis in children. J Pediatr Orthop. 1999;19:413-6. (Pubitemid 29214992)
12. Saavedra-Lozano J, Mejías A, Ahmad N, Peromingo E, Ardura MI, Guillen S, Syed A, Cavuoti D, Ramilo O. Changing trends in acute osteomyelitis in children: impact of methicillin-resistant Staphylococcus aureus infections. J Pediatr Orthop. 2008;28:569-75.
13. Zetola N, Francis JS, Nuermberger EL, Bishai WR. Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat. Lancet Infect Dis. 2005;5:275-86. (Pubitemid 40602247)
14. Martínez-Aguilar G, Avalos-Mishaan A, Hulten K, Hammerman W, Mason EO Jr, Kaplan SL. Community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus musculoskeletal infections in children. Pediatr Infec Dis J. 2004;23:701-6. (Pubitemid 39063283)
15. McCaskill ML, Mason EO Jr, Kaplan SL, Hammerman W, Lamberth LB, Hultén KG. Increase of the USA300 clone among community-acquired methicillinsusceptible Staphylococcus aureus causing invasive infections. Pediatr Infec Dis J. 2007;26:1122-7. (Pubitemid 350190944)
16. Sattler CA, Mason EO Jr, Kaplan SL. Prospective comparison of risk factors and demographic and clinical characteristics of community-acquired, methicillinresistant versus methicillin-susceptible Staphylococcus aureus infection in children. Pediatr Infect Dis J. 2002;21:910-7.
17. Bocchini CE, Hulten KG, Mason EO Jr, Gonzalez BE, Hammerman WA, Kaplan SL. Panton-Valentine leukocidin genes are associated with enhanced inflammatory response and local disease in acute hematogenous Staphylococcus aureus osteomyelitis in children. Pediatrics. 2006;117:433-40. (Pubitemid 46071606)
18. Crémieux AC, Dumitrescu O, Lina G, Vallee C, Côté JF, Muffat-Joly M, Lilin T, Etienne J, Vandenesch F, Saleh-Mghir A. Panton-valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis. PLoS ONE. 2009;4:e7204.
19. Dohin B, Gillet Y, Kohler R, Lina G, Vandenesch F, Vanhems P, Floret D, Etienne J. Pediatric bone and joint infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus. Pediatr Infect Dis J. 2007;26:1042-8. (Pubitemid 350287588)
20. Gillet Y, Dohin B, Dumitrescu O, Lina G, Vandenesch F, Etienne J, Floret D. [Osteoarticular infections with staphylococcus aureus secreting Panton-Valentine leucocidin]. Arch Pediatr. 2007;14 Suppl 2:S102-7French.
21. Hawkshead JJ 3rd, Patel NB, Steele RW, Heinrich SD. Comparative severity of pediatric osteomyelitis attributable to methicillin-resistant versus methicillinsensitive Staphylococcus aureus. J Pediatr Orthop. 2009;29:85-90.
22. Barczyński A, Gaździk TS, Pasierbek M. Atypical course of hematogenous osteomyelitis of the hip: a case report and clinical considerations. Orthop Traumatol Rehabil. 2003;5:92-9. (Pubitemid 38647703)
23. Daoud A, Saighi-Bouaouina A. Treatment of sequestra, pseudarthroses, and defects in the long bones of children who have chronic hematogenous osteomyelitis. J Bone Joint Surg Am. 1989;71:1448-68. (Pubitemid 20054461)
24. Devnani AS. Management of pathological fracture neck of the femur following recent osteomyelitis in a child. Singapore Med J. 2002;43:205-7.
25. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-1995. A previously well, 29 year-old woman with a pathologic fracture of the femur. N Engl J Med. 1995;333:507-11.
26. Ebong WW. Pathological fracture complicating long bone osteomyelitis in patients with sickle cell disease. J Pediatr Orthop. 1986;6:177-81. (Pubitemid 16154041)
27. Gelfand MS, Cleveland KO, Heck RK, Goswami R. Pathological fracture in acute osteomyelitis of long bones secondary to community-acquired methicillin-resistant Staphylococcus aureus: two cases and review of the literature. Am J Med Sci. 2006;322:357-60. (Pubitemid 46005832)
28. Pick RY, Segal D. Case report. Pathological subtrochanteric fracture in an infant: an unusual disease complex and a successful result. J Pediatr Orthop. 1981;1:209- 13.
29. Taylor MN, Chaudhuri R, Davis J, Novelli V, Jaswon MS. Childhood osteomyelitis presenting as a pathological fracture. Clin Radiol. 2008;63:348-51. (Pubitemid 351222661)
30. Walmsley BH. Pathological fracture in acute osteomyelitis in an adult. J R Soc Med. 1983;76:77-8. (Pubitemid 13176323)
31. Herigon JC, Hersh AL, Gerber JS, Zaoutis TE, Newland JG. Antibiotic management of Staphylococcus aureus infections in US children's hospitals, 1999-2008. Pediatrics. 2010;125:e1294-300.
32. Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, Kaplan SL, Karchmer AW, Levine DP, Murray BE, J Rybak M, Talan DA, Chambers HF. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary. Clin Infect Dis. 2011;52:285-92.
33. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: 19th informational supplement M100-S19. Clinical and Laboratory Standards Institute: Wayne, PA; 2009.
34. Hultén KG, Kaplan SL, Gonzalez BE, Hammerman WA, Lamberth LB, Versalovic J, Mason EO Jr. Three-year surveillance of community onset health care-associated staphylococcus aureus infections in children. Pediatr Infect Dis J. 2006;25:349-53.
35. Pugh J, Sherry HS, Futterman B, Frankel VH. Biomechanics of pathologic fractures. Clin Orthop Relat Res. 1982;169:109-14. (Pubitemid 12021016)
36. Ortiz EJ, Isler MH, Navia JE, Canosa R. Pathologic fractures in children. Clin Orthop Relat Res. 2005;432:116-26. (Pubitemid 40326254)
37. Damron T, Morgan H, Prakash D, Grant W, Aronowitz J, Heiner J. Metastatic disease of long bones. Clin Orthop Relat Res. 2003;415:201-7.
38. Quraishi NA, Davidson RN, Steele N, Grand F. Histoplasmosis as the cause of a pathological fracture. J Bone Joint Surg Br. 2003;85:732-3. (Pubitemid 36927042)
39. Seddon DJ, Thanabalasingham T, Weinberg J. Spontaneous fracture of the ulna complicating tuberculous osteomyelitis. Postgrad Med J. 1989;65:939-40. (Pubitemid 20013663)
40. Vander Have KL, Karmazyn B, Verma M, Caird MS, Hensinger RN, Farley FA, Lubicky JP. Community-associated methicillin-resistant Staphylococcus aureus in acute musculoskeletal infection in children: a game changer. J Pediatr Orthop. 2009;29:927-31.
41. Leong NL, Anderson ME, Gebhardt MC, Snyder BD. Computed tomographybased structural analysis for predicting fracture risk in children with benign skeletal neoplasms: comparison of specificity with that of plain radiographs. J Bone Joint Surg Am. 2010;92:1827-33.
42. Snyder BD, Hauser-Kara DA, Hipp JA, Zurakowski D, Hecht AC, Gebhardt MC. Predicting fracture through benign skeletal lesions with quantitative computed tomography. J Bone Joint Surg Am. 2006;88:55-70. (Pubitemid 43062773)