Effect of antibiotic prescribing in primary care on meticillin-resistant Staphylococcus aureus carriage in community-resident adults: A controlled observational study

International Journal of Antimicrobial Agents

Volumn 39, Issue 2, 2012, Pages 135-141

  Costelloe, Céire ^a   Lovering, Andrew ^b   Montgomery, Alan ^a   Lewis, Deirdre ^c   McNulty, Cliodna ^d   Hay, Alastair D ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

Author keywords

Antibiotics; Drug resistance; MRSA; Patient level data; Primary health care

Indexed keywords

ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CEFOXITIN; CIPROFLOXACIN; DOXYCYCLINE; ERYTHROMYCIN; METICILLIN; TRIMETHOPRIM;

ADULT; AGE DISTRIBUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; COMMUNITY CARE; CONTROLLED STUDY; ELECTRONIC MEDICAL RECORD; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OBSERVATIONAL STUDY; PRESCRIPTION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; UNITED KINGDOM;

ADULT; AGED; ANTI-BACTERIAL AGENTS; CARRIER STATE; CEFOXITIN; FEMALE; GREAT BRITAIN; HUMANS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; NOSE; PRESCRIPTIONS; PRIMARY HEALTH CARE; QUESTIONNAIRES; STAPHYLOCOCCAL INFECTIONS;

EID: 84855511995     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2011.09.022     Document Type: Article

References (28)

1. Klevens RM, Morrison MA, Nadle J, Petit S, Gershman K, Ray S, et al. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 2007;298:1763-71. (Pubitemid 47598444)
2. Tiemersma EW, Bronzwaer SL, Lyytikainen O, Degener JE, Schrijnemakers P, Bruinsma N, et al. Methicillin-resistant Staphylococcus aureus in Europe, 1999-2002. Emerg Infect Dis 2004;10:1627-34. (Pubitemid 39201515)
3. Diekema DJ, Boots Miller BJ, Vaughn TE, Woolson RF, Yankey JW, Ernst EJ, et al. Antimicrobial resistance trends and outbreak frequency in United States hospitals. Clin Infect Dis 2004;38:78-85. (Pubitemid 38045876)
4. Thompson K, Torriani F. Community-associated methicillin-resistant Staphylococcus aureus in the patient with HIV infection. Curr HIV/AIDS Rep 2006;3:107-12. (Pubitemid 44874995)
5. Thompson M. An audit demonstrating a reduction in MRSA infection in a specialised vascular unit resulting from a change in infection control protocol. Eur J Vasc Endovasc Surg 2006;31:609-15. (Pubitemid 43792956)
6. Mainous 3rd AG, Hueston WJ, Everett CJ, Diaz VA. Nasal carriage of Staphylococcus aureus and methicillin-resistant S. aureus in the United States, 2001-2002. Ann Fam Med 2006;4:132-7.
7. Lu PL, Chin LC, Peng CF, Chiang YH, Chen TP, Ma L, et al. Risk factors and molecular analysis of community methicillin-resistant Staphylococcus aureus carriage. J Clin Microbiol 2005;43:132-9. (Pubitemid 40096290)
8. Cooke J. Report of the Prescribing Subgroup of the Specialist Advisory Committee on Antimicrobial Resistance (SACAR). J Antimicrob Chemother 2007;60(Suppl. 1):i9-13.
9. Mulqueen J, Cafferty F, Cormican M, Keane JD, Rossney A. Nasal carriage of meticillin-resistant Staphylococcus aureus in GPs in the West of Ireland. Br J Gen Pract 2007;57:811-3. (Pubitemid 47595530)
10. Harbarth S, Samore MH. Antimicrobial resistance determinants and future control. Emerg Infect Dis 2005;11:794-801. (Pubitemid 40720837)
11. Asensio A, Guerrero A, Quereda C, Lizan M, Martinez-Ferrer M. Colonization and infection with methicillin-resistant Staphylococcus aureus: associated factors and eradication. Infect Control Hosp Epidemiol 1996;17:20-8. (Pubitemid 126482558)
12. David MZ, Daum RS. Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev 2010;23:616-87.
13. Crossley K. Long-term care facilities as sources of antibiotic-resistant nosocomial pathogens. Curr Opin Infect Dis 2001;14:455-9. (Pubitemid 32675493)
14. Hershow RC, Khayr WF, Smith NL. A comparison of clinical virulence of nosocomially acquired methicillin-resistant and methicillin-sensitive Staphylococcus aureus infections in a university hospital. Infect Control Hosp Epidemiol 1992;13:587-93.
15. Perl TM, Golub JE. New approaches to reduce Staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriage. Ann Pharmacother 1998;32:S7-16.
16. Corbella X, Dominguez MA, Pujol M, Ayats J, Sendra M, Pallares R, et al. Staphylococcus aureus nasal carriage as a marker for subsequent staphylococcal infections in intensive care unit patients. Eur J Clin Microbiol Infect Dis 1997;16:351-7. (Pubitemid 27271822)
17. Ellis MW, Hospenthal DR, Dooley DP, Gray PJ, Murray CK. Natural history of community-acquired methicillin-resistant Staphylococcus aureus colonization and infection in soldiers. Clin Infect Dis 2004;39:971-9. (Pubitemid 39313452)
18. Standing Medical Advisory Committee. The path of least resistance. London, UK: Department of Health; 1998.
19. Costelloe C, Metcalfe C, Lovering A, Mant D, Hay AD. Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis. BMJ 2010;340:c2096.
20. Hay AD, Thomas M, Montgomery A, Wetherell M, Lovering A, McNulty C, et al. The relationship between primary care antibiotic prescribing and bacterial resistance in adults in the community: a controlled observational study using individual patient data. J Antimicrob Chemother 2005;56:146-53. (Pubitemid 41418349)
21. Tacconelli E, De Angelis G, Cataldo MA, Pozzi E, Cauda R. Does antibiotic exposure increase the risk of methicillin-resistant Staphylococcus aureus (MRSA) isolation? A systematic review and meta-analysis. J Antimicrob Chemother 2008;61:26-38.
22. Andrews JM. Determination of minimum inhibitory concentrations. J Antimicrob Chemother 2001;48:5-16.
23. Fernandes CJ, Fernandes LA, Collignon P; Australian Group on Antimicrobial Resistance. Cefoxitin resistance as a surrogate marker for the detection of methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 2005;55:506-10. (Pubitemid 40542591)
24. British National Formulary. British National Formulary. 53rd ed. London, UK: Pharmaceutical Press; 2007.
25. Delaney JA, Schneider-Lindner V, Brassard P, Suissa S. Mortality after infection with methicillin-resistant Staphylococcus aureus (MRSA) diagnosed in the community. BMC Med 2008;6:2.
26. O'Donoghue MM, Boost MV. The prevalence and source of methicillin-resistant Staphylococcus aureus (MRSA) in the community in Hong Kong. Epidemiol Infect 2004;132:1091-7. (Pubitemid 39642390)
27. Baggett HC, Hennessy TW, Rudolph K, Bruden D, Reasonover A, Parkinson A, et al. Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton - Valentine leukocidin during a furunculosis outbreak in rural Alaska. J Infect Dis 2004;189:1565-73. (Pubitemid 38648283)
28. Charlebois ED, Bangsberg DR, Moss NJ, Moore MR, Moss AR, Chambers HF, et al. Population-based community prevalence of methicillin-resistant Staphylococcus aureus in the urban poor of San Francisco. Clin Infect Dis 2002;34:425-33. (Pubitemid 34112261)