The effect of hypoxia and work intensity on insulin resistance in type 2 diabetes

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 1, 2012, Pages 155-162

  Mackenzie, R ^a   Elliott, B ^a   Maxwell, N ^b   Brickley, G ^b   Watt, P ^b  

^a UNIVERSITY OF WESTMINSTER   (United Kingdom)

^b UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LACTIC ACID;

ADULT; ARTICLE; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; EXERCISE INTENSITY; GLUCOSE METABOLISM; HOMEOSTASIS; HUMAN; HYPOXIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TASK PERFORMANCE;

ADULT; ANOXIA; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; EXERCISE; FASTING; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; PHYSICAL EXERTION; WORKLOAD;

EID: 84855492456     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-1843     Document Type: Article

References (37)

1. Larkin M 2001 Diet and exercise delay onset of type 2 diabetes, say US experts. Lancet 358:565
2. Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M; Finnish Diabetes Prevention Study Group 2001 Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343-1350
3. Vermeire E, Wens J, Van Royen P, Biot Y, Hearnshaw H, Lindenmeyer A 2005 Interventions for improving adherence to treatment recommendations in people with type 2 diabetes mellitus. Cochrane Database Syst Rev 2:CD003638
4. Baynard T, Franklin RM, Goulopoulou S, Carhart Jr R, Kanaley JA 2005 Effect of a single vs multiple bouts of exercise on glucose control in women with type 2 diabetes. Metabolism 54:989-994 (Pubitemid 41033097)
5. 2*) in individuals with type 2 diabetes. Diabetes Metab Res Rev 27:94-101
6. Hayashi Y, Nagasaka S, Takahashi N, Kusaka I, Ishibashi S,Numao S, Lee DJ, Taki Y, Ogata H, Tokuyama K, Tanaka K 2005 A single bout of exercise at higher intensity enhances glucose effectiveness in sedentary men. J Clin Endocrinol Metab 90:4035-4040 (Pubitemid 41058168)
7. KraniouGN,Cameron-Smith D, HargreavesM2006 Acute exercise and GLUT4 expression in human skeletal muscle: influence of exercise intensity. J Appl Physiol 101:934-937 (Pubitemid 44352310)
8. Cartee GD, Douen AG, Ramlal T, Klip A, Holloszy JO 1991 Stimulation of glucose transport in skeletal muscle by hypoxia. J Appl Physiol 70:1593-1600
9. Chiu LL, Chou SW, Cho YM, Ho HY, Ivy JL, Hunt D, Wang PS, Kuo CH 2004 Effect of prolonged intermittent hypoxia and exercise training on glucose tolerance and muscle GLUT4 protein expression in rats. J Biomed Sci 11:838-846 (Pubitemid 39664238)
10. Azevedo Jr JL, Carey JO, Pories WJ, Morris PG, Dohm GL 1995 Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle. Diabetes 44:695-698
11. Kennedy JW, Hirshman MF, Gervino EV, Ocel JV, Forse RA, Hoenig SJ, Aronson D, Goodyear LJ, Horton ES 1999 Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes. Diabetes 48:1192-1197 (Pubitemid 29226370)
12. Fisher JS, Gao J, Han DH, Holloszy JO, Nolte LA 2002 Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin. Am J Physiol Endocrinol Metab 282:E18-E23 (Pubitemid 34654101)
13. Heller JB 2007 Metformin overdose in dogs and cats. Vet Med 4:231-233
14. Kashiwazaki H, Inaoka T, Suzuki T, Kondo Y 1986 Correlations of pedometer readings with energy expenditure in workers during freeliving daily activities. Eur J Appl Physiol Occup Physiol 54:585-590 (Pubitemid 16148432)
15. Uwaifo GI, Fallon EM, Chin J, Elberg J, Parikh SJ, Yanovski JA 2002 Indices of insulin action, disposal, and secretion derived from fasting samples and clamps in normal glucose-tolerant Black and White children. Diabetes Care 25:2081-2087
16. Brooks GA, Butterfield GE, Wolfe RR, Groves BM, Mazzeo RS, Sutton JR, Wolfel EE, Reeves JT 1991 Increased dependence on blood glucose after acclimatization to 4,300 m. J Appl Physiol 70:919-927
17. Salt IP, Connell JM, Gould GW 2000 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes 49:1649-1656
18. Fernandez-Real JM, Vayreda M, Richart C, Gutierrez C, Broch M, Vendrell J, Ricart W 2001 Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women. J Clin Endocrinol Metab 86:1154-1159 (Pubitemid 32322997)
19. Katsuki A, Sumida Y, Gabazza EC, Murashima S, Furuta M, Araki- Sasaki R, Hori Y, Yano Y, Adachi Y 2001 Homeostasis model assessment is a reliable indicator of insulin resistance during follow-up of patients with type 2 diabetes. Diabetes Care 24:362-365
20. Steele R 1959 Influences of glucose loading and of injected insulin on hepatic glucose output. Ann NY Acad Sci 82:420-430
21. Gastaldelli A, Coggan AR, Wolfe RR 1999 Assessment of methods for improving tracer estimation of non-steady-state rate of appearance. J Appl Physiol 87:1813-1822
22. Rosenblatt J, Chinkes D, Wolfe M, Wolfe RR 1992 Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects. Am J Physiol 263(3 Pt 1):E584-E596
23. Finegood DT, Miles PD, Lickley HL, Vranic M 1992 Estimation of glucose production during exercise with a one-compartment variable-volume model. J Appl Physiol 72:2501-2509
24. DeFronzo RA, Ferrannini E, Sato Y, Felig P, Wahren J 1981 Synergistic interaction between exercise and insulin on peripheral glucose uptake. J Clin Invest 68:1468-1474 (Pubitemid 12194401)
25. Dela F, Mikines KJ, Sonne B, Galbo H 1994 Effect of training on interaction between insulin and exercise in human muscle. J Appl Physiol 76:2386-2393 (Pubitemid 24184757)
26. Rose AJ, Richter EA 2005 Skeletal muscle glucose uptake during exercise: how is it regulated? Physiology 20:260-270 (Pubitemid 41215200)
27. Roy D, Jóhannsson E, Bonen A, Marette A 1997 Electrical stimulation induces fiber type-specific translocation of GLUT-4 to T tubules in skeletal muscle. Am J Physiol 273(4 Pt 1):E688-E694
28. Chen ZP, Stephens TJ, Murthy S, Canny BJ, Hargreaves M, Witters LA, Kemp BE, McConell GK 2003 Effect of exercise intensity on skeletal muscle AMPK signaling in humans. Diabetes 52:2205-2212 (Pubitemid 37059489)
29. Wadley GD, Lee-Young RS, Canny BJ, Wasuntarawat C, Chen ZP, Hargreaves M, Kemp BE, McConell GK 2006 Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans. Am J Physiol Endocrinol Metab 290:E694-702
30. Kang J, Kelley DE, Robertson RJ, Goss FL, Suminski RR, Utter AC, Dasilva SG 1999 Substrate utilization and glucose turnover during exercise of varying intensities in individuals with NIDDM. Med Sci Sports Exerc 31:82-89 (Pubitemid 29036363)
31. Bordenave S, Brandou F, Manetta J, Fédou C, Mercier J, Brun JF 2008 Effects of acute exercise on insulin sensitivity, glucose effectiveness and disposition index in type 2 diabetic patients. Diabetes Metab 34:250-257
32. Wojtaszewski JF, MacDonald C, Nielsen JN, Hellsten Y, Hardie DG, Kemp BE, Kiens B, Richter EA 2003 Regulation of 5 AMP activated protein kinase activity and substrate utilization in exercising human skeletal muscle. Am J Physiol Endocrinol Metab 284:E813-E822 (Pubitemid 36323876)
33. Hughson RL, Green HJ, Sharratt MT 1995 Gas exchange, blood lactate, and plasma catecholamines during incremental exercise in hypoxia and normoxia. J Appl Physiol 79:1134-1141
34. Koval JA, DeFronzo RA, O'Doherty RM, Printz R, Ardehali H, Granner DK, Mandarino LJ 1998 Regulation of hexokinase II activity and expression in human muscle by moderate exercise. Am J Physiol 274(2 Pt 1):E304-E308
35. 3-AMPK trimeric complex in skeletal muscle during exercise in humans. Am J Physiol Endocrinol Metab 292: E715-722
36. Akerstrom TC, Birk JB, Klein DK, Erikstrup C, Plomgaard P, Pedersen BK, Wojtaszewski J 2006 Oral glucose ingestion attenuates exercise-induced activation of 5-AMP-activated protein kinase in human skeletal muscle. Biochem Biophys Res Commun 14:949-955 (Pubitemid 43320489)
37. Witters LA, Kemp BE 1992 Insulin activation of acetyl-CoA carboxylase accompanied by inhibition of the 5′-AMP-activated protein kinase. J Biol Chem 267:2864-2867