Sublingual mucosa as a route for systemic drug delivery

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 3, Issue SUPPL. 2, 2011, Pages 18-22

  Narang, Neha ^a,b   Sharma, Jyoti ^a,b  

^a Shri Baba Mastnath Institute of Pharmaceutical Sciences and Research ^*  (India)

^b KURUKSHETRA UNIVERSITY   (India)

Author keywords

Dysphagia; Improved bioavailability; Oral cavity; Sublingual delivery

Indexed keywords

AMLODIPINE BESYLATE; APOMORPHINE; ASENAPINE; BUPRENORPHINE; BUPRENORPHINE PLUS NALOXONE; CAPTOPRIL; CORTISONE ACETATE; EDULAR; ESTRADIOL; FENTANYL; FENTANYL CITRATE; FUROSEMIDE; GLYCERYL TRINITRATE; HYDRAZINE; ISOSORBIDE DINITRATE; LORAZEPAM; MELATONIN; MORPHINE; NALOXONE; NICOTINE GUM; NICOTINE TARTRATE; NIFEDIPINE; ONDANSETRON; PHYSOSTIGMINE SALICYLATE; PROCHLORPERAZINE MALEATE; RETINOL; SALBUTAMOL SULFATE; SCOPOLAMINE; TERBUTALINE SULFATE; UNCLASSIFIED DRUG; VERAPAMIL; VINPOCETINE; ZOLPIDEM TARTRATE;

ANGINA PECTORIS; AREA UNDER THE CURVE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG METABOLISM; DRUG PENETRATION; DRUG SOLUBILITY; HEART SUPRAVENTRICULAR ARRHYTHMIA; HUMAN; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; LIPOPHILICITY; MAXIMUM PLASMA CONCENTRATION; MOUTH MUCOSA; OSMOSIS; PARTITION COEFFICIENT; REVIEW; SUBLINGUAL DRUG ADMINISTRATION; SUBLINGUAL GLAND; TABLET DISINTEGRATION TIME; TENSILE STRENGTH; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 84855471651     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Review

References (37)

1. Ishikawa T, Koizumi N, Mukai B. Pharmacokinetics of acetaminophen from rapidly disintegrating compressed tablet prepared using microcrystalline cellulose (PH-M-06) and spherical sugar granules. Chem Pharm Bull (Tokyo) 2001; 49: 230-232.
2. Price TM, Blauer KL, Hansen M, Stanczyk F, Lobo R, Bates GW. Single-dose pharmacokinetics of sublingual versus oral administration of micronized 17 beta-estradiol. Obstet Gynecol 1997; 89: 340-345.
3. R.P Walton Absorption of drugs through the oral mucosa. III Fat-water solubility coefficient of alkaloids. Proc Soc Exp Bio Med 1935; 32: 1488.
4. Kurosaki Y, Takatori T, Nishimura H, Nakayama T, Kimura T Regional variation in oral mucosal drug absorption permeability and degree of keratinization in hamster oral cavity. Pharm Res 1991; 8: 1297-1301.
5. Ghosh TK, Chatterjee DJ, Pfister WR. Quick dissolving oral dosage forms: Scientific and regulatory considerations from a clinical pharmacology and biopharmaceutical perspective. In: Ghosh TK and Pfister WR (Eds). Drug Delivery to the Oral Cavity Molecules to Market. NY, USA: CRC Press, 2005: 337-356.
6. Shojaie AH. Buccal mucosa as a route for systemic drug delivery: A review. J Pharm Pharm Sci 1998; 1(1):15-30.
7. Richman MD, Fox D, Shangraw RF. Preparation and stability of glyceryl trinitrate sublingual tablets prepared by direct compression. J Pharm Sci 1965; 54(3): 447-451.
8. John DN, Fort S, Lewis MJ, Luscombe DK. Pharmacokinetics and pharmacodynamics of Verapamil following sublingual and oral administration to healthy volunteers. Br J Clin Pham 1992; 33: 623-627.
9. McElnay JC, Al-Furaih TA, Hughes CM, Scott MG, Elborn JS, Nicholls DP. The effect of pH on the buccal and sublingual absorption of captopril. Eur J Clin Pharmacol 1995; 48(5): 373-379.
10. Mary Elizabeth RN, Martelli BS. Sublingual and buccal medication administration. Encyclopedia of Nursing and Allied Health, 20050229
11. Lea L. Sublingual Administration. Colon Health 1996; 13
12. Boer D et al. Drug absorption by sublingual and rectal routes. British J Anaesthesia 1984; 56: 69-82.
13. Al-Ghananeem AM, Malkawi AH, Crooks PA. Effect of pH on Sublingual Absorption of Oxycodone Hydrochloride. AAPS PharmSciTech 2006; 7(1): Article 23.
14. Katz M, Barr M. A study of sublingual absorption I. Several factors influencing the rate of adsorption. J Am Pharm Assoc Am Pharm Assoc (Baltim) 1955; 44(7): 419-423.
15. Allen LV. Rapid-dissolve technology: an interview Int J Pharm Technol 2003; 7:449-450.
16. Fu Y, Yang S, Jeong SH, Kimura S, Park K. Orally fast disintegrating tablets: developments, technologies, tastemaking and clinical studies. Crit Rev Ther Drug Carrier Syst 2004; 21: 433-476.
17. Weinberger M. Pharmacological management of Asthma. J Adolescent Health Care 1987; 8(1): 74-83.
18. Nafee NA, Boraie NA, Ismail FA, Mortada IM. Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride. Acta Pharm 2003; 53: 199-212.
19. Koland M, Sandeep VP, Charyulu NR. Fast dissolving sublingual films of ondansetron hydrochloride: effect of additives on invitro drug release and mucosal permeation. J Young Pharm 2010; 2(3): 216-222.
20. Bottenbrg P, Cleymact R, dc Muynck C, Reymon JP, Coomans D, Michotte Y et al. Development and testing of fluoride containing slow release tablets for oral use. J Pharm Pharmacol 1991; 43: 457-464.
21. Peh KK, Wong CF. Polymeric films as vehicles for buccal delivery; swelling, mechanical, and bioadhesive properties. J Pharm Sci 1999; 2: 53-61.
22. USP/NF. Physical Tests: Disintegration (701) 22/17 ed. Rockville, MD: United States Pharmacopoeial Convention Inc; 1990.
23. USP/NF. Official Monographs: Nitroglycerin Tablets. 22/17 ed. Rockville, MD: United States Pharmacopoeial Convention Inc; 1990.
24. Bi Y, Sunada H, Yonezawa Y, Danjo K, Otsuka A, Iida K. Preparation and evaluation of a compressed tablet rapidly disintegrating in the oral cavity. Chem Pharm Bull (Tokyo) 1996; 44: 2121-2127.
25. Narendra C, Srinath MS, Rao PB. Formulation and evaluation of a sublingual tablet containing terbutaline sulphate: optimization and in vivo studies. Ars Pharmaceutica 2005; 46(2): 139-158.
26. Patel MV, Prajapati BG, Patel MM. Effect of hydrophilic polymers on buccoadhesive Eudragit patches of propranolol hydrochloride using factorial design. AAPS PharmSciTech 2007; 8: Article 45.
27. Semalty M, Semalty A, Kumar G. Formulation and characterization of mucoadhesive buccal films of glipizide. Indian J Pharm Sci 2008; 70:43-48.
28. Bolourtchian N, Hadidi N, Foroutan SM, Shafaghi B. Development and optimization of sublingual tablet formulation for Physostigmine Salicylate. Acta Pharm 2009; 59: 301-312.
29. Al-Ghananeem AM, Malkawi AH, Crooks PA. Scopolamine sublingual spray: an alternative route of delivery for the treatment of motion sickness. Drug Dev Ind Pharm, 2007; 33(5):577-582.
30. Bolourtchian N, Hadidi N, Foroutan SM, Shafaghi B. Formulation and optimization of captopril sublingual tablet using D-Optimal design. Iranian J Pharm Res 2008; 7(4): 259-267.
31. Haegeli L, Brunner-La Rocca HP, Wenk M, Pfisterer M, Drewe J, Krahenbuhl S. Sublingual administration of furosemide: new application of an old drug. B J Clin Pharmcol 2007; 64(6): 804-809.
32. Sheeba FR, Acharya GD, Rameshwari S, Jeya AJ. Formulation and evaluation of nifedipine sublingual tablets. Asian J Pharm Clinical Res 2009; 2(3): 44-48.
33. Centkowska K, Sznitowska M. Comparison of sublingual tablets with nitroglycerin complexed with β-Cyclodextrin or titrated with crosspovidone - Technological approach. Acta Pol Pharm- Drug Res 2008; 65(5): 585-589.
34. Aburahma MH, El-Laithy HM, Hamza YE. Preparation and In Vitro/In Vivo Characterization of porous sublingual tablets containing ternary kneaded solid system of Vinpocetine with β- Cyclodextrin and hydroxy acid. Sci Pharm 2010; 78; 363-379.
35. Narendra C, Srinath MS, Rao PB. Formulation and evaluation of sublingual tablet containing terbutaline sulphate: optimization and in vivo studies. Ars Pharm 2005; 46(2): 138-158. 36
36. Bhardwaj V, Shukla V, Goyal N, Salim MD, Sharma PK. Formulation and evaluation of fast disintegrating sublingual tablets of amlodipine besylate using different superdisintegrants. Int J Pharmacy Pharm Sci 2010; 2(3): 89-92.
37. Sutariya V, Mashru R, Sankalia M. Development of fast dissolving sublingual film of salbutamol sulphate for acute asthmatic attack management: In vitro and In vivo study AAPS PharmSciTech 2006-001051.