Tissue preparation for the in situ MALDI MS imaging of proteins, lipids, and small molecules at cellular resolution

Methods in Molecular Biology

Volumn 656, Issue , 2010, Pages 415-431

  Agar, Nathalie Y R ^a   Kowalski, Jane Marie ^b   Kowalski, Paul J ^b   Wong, John H ^c   Agar, Jeffrey N ^c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BRUKER DALTONIK GMBH   (Germany)

^c BRANDEIS UNIVERSITY   (United States)

Author keywords

imaging; Mass spectrometry; matrix solution fixation; optimization; single cell

Indexed keywords

LIPID; PROTEIN;

ANIMAL; ARTICLE; CHEMISTRY; CONFOCAL MICROSCOPY; DIAGNOSTIC IMAGING; MASS SPECTROMETRY; METHODOLOGY; MOUSE; SCANNING ELECTRON MICROSCOPY; TRANSGENIC MOUSE;

ANIMALS; DIAGNOSTIC IMAGING; LIPIDS; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84855468116     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-746-4_24     Document Type: Article

References (22)

1. Gusev, A. I., Vasseur, O. J., Proctor, A., Sharkey, A. G., Hercules, D.M. (1995) Imaging of thin-layer chromatograms using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem, 67, 4565-4570.
2. Aerni, H. R., Cornett, D. S., Caprioli, R. M. (2006) Automated acoustic matrix deposition for MALDI sample preparation. Anal Chem, 78, 827-834.
3. Sloane, A. J., Duff, J. L., Wilson, N. L., Gandhi, P. S., Hill, C. J., Hopwood, F. G., Smith, P. E., Thomas, M. L., Cole, R. A., Packer, N. H., et al. (2002) High throughput peptide mass fingerprinting and protein macroarray analysis using chemical printing strategies.Mol Cell Proteomics, 1, 490-499.
4. Schwartz, S. A., Reyzer, M. L., Caprioli, R. M. (2003) Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: Practical aspects of sample preparation. J Mass Spectrom, 38, 699-708.
5. Jurchen, J. C., Rubakhin, S. S., Sweedler, J. V. (2005) MALDI-MS imaging of features smaller than the size of the laser beam. J Am Soc Mass Spectrom, 16, 1654-1659.
6. Puolitaival, S. M., Burnum, K. E., Cornett, D. S., Caprioli, R. M. (2008) Solvent-free matrix dry-coating for MALDI imaging of phospholipids. J Am Soc Mass Spectrom, 19, 882-886.
7. Lemaire, R., Wisztorski, M., Desmons, A., Tabet, J. C., Day, R., Salzet, M., Fournier, I. (2006) MALDI-MS direct tissue analysis of proteins: Improving signal sensitivity using organic treatments. Anal Chem, 78, 7145-7153.
8. Agar, N. Y., Yang, H. W., Carroll, R. S., Black, P. M., Agar, J. N. (2007) Matrix Tissue Preparation for the In Situ MALDI MS Imaging 431 solution fixation: Histology-compatible tissue preparation for MALDI mass spectrometry imaging. Anal Chem, 79, 7416-7423.
9. Clarke, J. L. (1851) Researches into the structure of the spinal cord. Phil Trans Roy Soc, 141, 601-622.
10. Carnoy, J. B. (1887) La cytodierese de l'oeuf. Cellule, 3, 6.
11. Blum, F. (1893) Der Formaldehyde als Hartungsmittel. Vorlaufige Mittheilung. Z.w.M., 10, 314-315.
12. Prausnitz, J. M. (2003) Molecular thermodynamics for some applications in biotechnology. Pure Appl Chem, 75, 859-873.
13. Xu, B. J., Li, J., Beauchamp, R. D., Shyr, Y., Li, M., Washington, M. K., Yeatman, T. J., Whitehead, R. H., Coffey, R. J., Caprioli, R. M. (2009) Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS. Mol Cell Proteomics, 8, 936-945.
14. Neupert, S., Johard, H. A., Nassel, D. R., Predel, R. (2007) Single-cell peptidomics of drosophila melanogaster neurons identified by Gal4-driven fluorescence. Anal Chem, 79, 3690-3694.
15. Monroe, E. B., Jurchen, J. C., Koszczuk, B. A., Losh, J. L., Rubakhin, S. S. Sweedler, J. V. (2006) Massively parallel sample preparation for the MALDI MS analyses of tissues. Anal Chem, 78, 6826-6832.
16. Holle, A., Haase, A., Kayser, M., Hohndorf, J. (2006) Optimizing UV laser focus profiles for improved MALDI performance. J Mass Spectrom, 41, 705-716.
17. Spengler, B., Hubert, M. (2002) Scanning microprobe matrix-assisted laser desorption ionization (SMALDI) mass spectrometry: Instrumentation for sub-micrometer resolved LDI and MALDI surface analysis. J Am Soc Mass Spectrom, 13, 735-748.
18. Luxembourg, S. L., Mize, T. H., McDonnell, L. A., Heeren, R. M. (2004) Highspatial resolution mass spectrometric imaging of peptide and protein distributions on a surface. Anal Chem, 76, 5339-5344.
19. Luxembourg, S. L., McDonnell, L. A., Mize, T. H., Heeren, R. M. (2005) Infrared mass spectrometric imaging below the diffraction limit. J Proteome Res, 4, 671-673.
20. Goodwin, R. J., Dungworth, J. C., Cobb, S. R., Pitt, A. R. (2008) Time-dependent evolution of tissue markers by MALDI-MS imaging. Proteomics, 8, 3801-3808.
21. Schaefer, A. M., Sanes, J. R., Lichtman, J. W. (2005) A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis. J Comp Neurol, 490, 209-219.
22. Lemaire, R., Tabet, J. C., Ducoroy, P., Hendra, J. B., Salzet, M., Fournier, I. (2006) Solid ionic matrixes for direct tissue analysis and MALDI imaging. Anal Chem, 78, 809-819.